Researchers found that male neurons more readily withered up and died under starvation, while female neurons conserved energy and stayed alive. The study revealed sex-dependent effects in brain cells, shedding light on metabolic differences between males and females.
SourceAmerican Society for Biochemistry and Molecular Biology·JournalJournal of Biological Chemistry·DateJan 16, 2009
A new study finds that high levels of FGF21 hormone cause mice to become resistant to growth hormone, stunting their growth. This discovery provides insights into the physiological role of FGF21 in energy conservation during food deprivation.
Researchers at Beth Israel Deaconess Medical Center have identified a 'food-related clock' that can supersede the body's primary biological rhythms, enabling better coping with changes in time zones and nighttime schedules. By adjusting eating schedules, humans may be able to adapt more quickly to new time zones.
SourceBeth Israel Deaconess Medical Center·JournalScience·DateMay 22, 2008
A team of researchers found that the protein TORC2 is crucial for glucose production and fat storage in Drosophila, a genetic switch that regulates metabolism in both flies and human livers. Without functional TORC, fly lifespan was cut in half and their ability to store energy was impaired.
SourceSalk Institute·JournalMolecular Cell·DateMay 6, 2008
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Research suggests that babies conceived during a period of famine are at increased risk of developing addictions later in life. The study, which examined the 1944-45 Dutch 'hunger winter,' found that pregnant women who experienced severe food shortages were more likely to have children with addictive disorders.
Researchers found that a key hormone called fibroblast growth factor 21 (FGF21) enables starving mice to alter their metabolism and induce a hibernation-like state, conserving energy. This discovery opens up new avenues for treating human obesity and metabolic disorders.
SourceUT Southwestern Medical Center·JournalCell Metabolism·DateJun 5, 2007
Researchers have identified a new 'starvation hormone' that plays a critical role in the metabolic shift seen in animals on low-carb, high-fat diets. Increased levels of liver-derived FGF21 hormone are required for mice to switch gears and begin burning fat.
SourceCell Press·JournalCell Metabolism·DateJun 5, 2007
Researchers have identified a conserved role for the muscarinic acetylcholine pathway in animal starvation responses, suggesting potential insights into eating disorders. The study found that starvation activates the MAPK enzyme in the pharyngeal muscles of C. elegans worms.
SourceCell Press·JournalCell Metabolism·DateApr 4, 2006
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Researchers discovered a biochemical reaction controlling how the worm feeds, which may help understand feeding disorders. The study suggests that inappropriate behavioral responses to starvation signals could be the cause of feeding disorders in mammals.
SourceUT Southwestern Medical Center·JournalCell Metabolism·DateApr 4, 2006
Diamond-back rattlesnakes survived for 5 ½ months without food, growing in length while reducing metabolic rate by 80%. The snakes used stored lipid energy sources and increased water content to maintain cellular shape.
Researchers have found that mitochondria function as oxygen sensors, producing reactive oxygen species in response to low oxygen conditions. However, a dual-mode mechanism involving the enzyme PHD emerges when oxygen levels are extremely low, suggesting a new strategy for enhancing the body's natural protective response.
SourceHoward Hughes Medical Institute·JournalCell Metabolism·DateJun 7, 2005
A study by PhD student Rebecca Cramp found that the green-striped burrowing frog can maintain its gut function despite prolonged starvation, allowing it to digest massive meals efficiently. The discovery has implications for human survival during starvation, as humans often experience severe gastrointestinal issues after re-feeding.
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A diverse network of marine protected areas may be essential for restoring depleted groundfish stocks. Older fish produce more eggs with increased survival chances for larvae, which can grow faster and survive starvation longer.
SourceOregon State University·JournalFisheries·DateJan 18, 2005
A new study by Mayo Clinic suggests that the ketogenic diet can be safely initiated as an outpatient treatment for children with epilepsy, offering improved acceptability and comfort. The study found no significant differences in long-term seizure control or mental improvement between inpatient and outpatient groups.
SourceMayo Clinic·JournalPediatric Neurology·DateOct 19, 2004
Researchers have found that penguins from the Punta Tombo reserve in southern Argentina travel more than 300 miles to find food, a significant increase from previously thought foraging ranges. The depletion of squid and other preferred foods is attributed to commercial fisheries and climate change.
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