Articles tagged with Calcium Signaling
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OHSU research reveals calcium ions modulate auditory nerve cells' recharging after bursting signals. High levels of calcium can be toxic, but regulating sodium pump activity conserves energy and prevents cell death.
A team of Canadian researchers discovered a distinct dopamine signalling complex in the brain, which may have a significant role in understanding and treating schizophrenia. This novel target involves two different types of dopamine receptors that only create brain signals when both are stimulated at the same time.
Researchers discovered that presenilins act as calcium channels, controlling the balance of calcium within cells. This finding may suggest a new avenue for treating Alzheimer's disease by restoring normal calcium levels. The study also highlights the potential for combination therapies targeting both amyloid and calcium signaling.
Researchers discovered that calcium fills a small structure in cells, forcing muscles to relax when full. This understanding can help doctors treat patients more accurately with the body's natural mechanisms.
Researchers have found that deliberate damage to sensory receptor cells in the inner ear can trigger a cascade of signals through ATP release, leading to the spread of calcium ions. This mechanism is activated by loud noise levels commonly experienced in nightclubs and when using personal headphones.
Researchers use high-speed imaging to track movement of calcium waves in cell signaling, identifying a sequence of amino acids (LTL) that controls the pathway. The findings have implications for treating autoimmune diseases such as arthritis and uveitis.
Researchers discovered a molecular switch that guides cell communication before a message reaches the nucleus, adding complexity to understanding cellular signals. This switch determines which signal - calcium or cAMP - will be used, leading to different responses in target proteins and potential therapies for serious disorders.
The LAT protein is essential for T-cell activation and a normal immune response. Mutations in the protein can lead to unbalanced signaling pathways, potentially causing autoimmune disorders.
Researchers found that estrogen production protects females from cardiac hypertrophy, but not males. By blocking estrogen receptors, female mice developed cardiac enlargement similar to males.