Researchers at the Helmholtz Centre for Infection Research established profilin as a master regulator of Arp2/3 complex-dependent actin networks, resolving controversies in cell migration research. The study's findings provide insights into the molecular logic of building branched actin networks driving membrane protrusion.
Apusomonads display a clear avoidance response to blue light by asymmetrizing their posterior flagellum and contracting their cell body. This primitive mechanism provides clues to the evolution of high-speed flagellar movements in opisthokonts.
A new study in The American Journal of Pathology found that inhibiting neuropilin 2 in smooth muscle can enhance contraction and motility of the distal colon. This could provide opportunities to regulate smooth muscle activity in patients with colonic disorders.