A new study by Grant Brown and Braeden Donaldson found that juvenile convict cichlids exposed to high-risk alarm cues have brains 16% larger compared to low-risk groups, with noticeable increases in olfactory and optic bulbs. The brains revert to normal size after removal of the alarm cues.
SourceConcordia University·JournalProceedings of the Zoological Society·TypeRandomized controlled/clinical trial·DateSep 27, 2022
Researchers discover that male spotted lanternflies are strongly attracted to the smell of honeydew produced by male conspecifics, emitting specific sex-attractant profiles. This finding may lead to the development of new pest management tools to reduce the population and spread of this invasive species.
SourceFrontiers·JournalFrontiers in Insect Science·TypeExperimental study·DateSep 27, 2022
Apple iPhone 17 Pro
Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
A joint research team from Korea and Japan developed site-specific organelle fluorescent thermometers that visualize temperature changes in almost all typical organelles. The new thermometers, called Thermo Greens (TGs), provide quantitative images of heat generation at different organelles, offering insights into cellular processes.
SourcePohang University of Science & Technology (POSTECH)·JournalMaterials Today Bio·DateSep 26, 2022
Researchers from the Institute of Physical Chemistry, Polish Academy of Sciences, have developed a novel polymer-based solution that enables easy delivery of large molecules to cells. By applying hypertonic solutions, they can induce osmotic stress and relax the cell membrane, allowing for precise control over molecule transfer.
SourceInstitute of Physical Chemistry of the Polish Academy of Sciences·JournalJournal of Colloid and Interface Science·DateSep 22, 2022
A new DNA-based fluorescence technique using single-molecule electron-transfer kinetics can identify point mutations in mRNA, facilitating the diagnosis of gliomas and potentially treating the disease. This breakthrough may lead to real-time cancer diagnostics during surgical biopsies, reducing the need for multiple surgeries.
SourceOsaka University·JournalChem·TypeExperimental study·DateAug 31, 2022
Researchers found a strong association between ultra-processed food consumption and adverse mental health symptoms, including depression, anxiety, and mentally unhealthy days. The study suggests that the high sugar, salt, and saturated fat content of ultra-processed foods may contribute to these negative effects.
SourceFlorida Atlantic University·JournalPublic Health Nutrition·TypeMeta-analysis·DateAug 25, 2022
Apple AirPods Pro (2nd Generation, USB-C)
Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.
Researchers developed a label-free Raman spectroscopy approach with enhanced sensitivity and speed, allowing for non-invasive imaging of biological samples. The new CARS microscopy system can acquire microscopic images and identify biomolecules with unprecedented resolution and speed.
Researchers at Karolinska Institutet have developed a method to create a three-dimensional gel from spider silk proteins that can be designed to deliver functional proteins. The gel has the potential to revolutionize regenerative medicine, enabling controlled drug release and tissue engineering applications.
SourceKarolinska Institutet·JournalNature Communications·DateAug 15, 2022
The workshop will discuss recent advances, perspectives, and applications of medical cannabis and cannabinoids. Researchers will explore their chemistry, pharmacology, analysis, influence on mitochondria, and potential use as anticancer agents.
Researchers developed a mathematical model to predict the efficiency of nanoparticle delivery into cells, particularly in stem cells. They found that nanoparticles become trapped in bubble-like vesicles, preventing them from reaching their targets.
SourceXi'an Jiaotong-Liverpool University·JournalACS Nano·TypeExperimental study·DateJul 20, 2022
Researchers at Ohio State University have developed an artificial protein that could provide new insights into chemical evolution on early Earth. The protein, inspired by a key enzyme in energy production, has been shown to build molecules one step at a time, shedding light on how organic chemistry matured on the planet.
SourceOhio State University·JournalProceedings of the National Academy of Sciences·TypeExperimental study·DateJul 20, 2022
CalDigit TS4 Thunderbolt 4 Dock
CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.
Scientists have created new fluorescent chemical compounds for photodynamic therapy of cancerous tumors, which can stain affected tissues and destroy tumor cells without harm to healthy ones. The compound containing pyrene shows the highest fluorescent and anticancer activity.
SourceUral Federal University·JournalDyes and Pigments·DateJun 27, 2022
Rensselaer researchers will use a five-year grant to develop novel inhibitors of the SARS-CoV-2 virus's CLpro and PLpro proteases. The team aims to create an orally bioavailable drug that can be administered at home, with the potential for improved antiviral activity when combined with other drugs like remdesivir.
Scientists have developed artificial photosynthesis to produce food in the dark, bypassing sunlight's need. This technology converts CO2, electricity, and water into acetate, a key component of vinegar, boosting food production's conversion efficiency up to 18 times.
SourceUniversity of California - Riverside·JournalNature Food·TypeExperimental study·DateJun 23, 2022
Researchers at Karolinska Institutet have improved the ability of a protein to repair oxidative DNA damage, creating a new drug development concept. The technique can lead to improved treatments for diseases involving oxidative stress.
Researchers have developed innovative tests for multiple chemicals using plant-based molecules that can detect synthetic cannabinoids and banned pesticides. The system uses a simple and inexpensive approach to quickly signal the presence of nearly 20 different chemicals.
SourceUniversity of California - Riverside·JournalNature Biotechnology·DateJun 21, 2022
Garmin GPSMAP 67i with inReach
Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.
A collaborative initiative aims to establish common protocols for assessing and comparing diffuse optics systems used in medical diagnosis. The study presents the results of a multi-laboratory comparison of 12 institutions and 28 systems, proposing simple numeric values for easy comparison across instruments.
SourceSPIE--International Society for Optics and Photonics·JournalJournal of Biomedical Optics·DateJun 15, 2022
Researchers at Karolinska Institutet describe a new way of generating insulin-producing cells using a molecule that stimulates protein synthesis and boosts insulin production. The study shows promise for treating type 1 and 2 diabetes, potentially increasing the number of insulin-producing pancreatic β cells.
SourceKarolinska Institutet·JournalNature Chemical Biology·DateJun 13, 2022
Researchers found that chemical pre-treatment can help microorganisms break down plastics more quickly. The process makes carbon, oxygen, and hydrogen from the plastic's molecular structure more accessible for bacteria to use as food.
Apple Watch Series 11 (GPS, 46mm)
Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.
Researchers have identified a regulatory network controlling zinc accumulation in marine cyanobacteria, allowing them to vary their internal zinc levels by over two orders of magnitude. This network is unique among bacteria, enabling the extraordinary capacity to accumulate zinc.
SourceUniversity of Warwick·JournalNature Chemical Biology·DateJun 9, 2022
A new platform mimics live cellular environment to guide stem cell differentiation outside the body. Researchers from Chung-Ang University developed a novel platform based on metal-organic frameworks, which offers advantages over conventional methods for in vitro stem cell differentiation.
SourceChung Ang University·JournalScience Advances·TypeExperimental study·DateJun 9, 2022
A study published in Journal of Pharmaceutical Analysis found that the quality of mistletoe, a traditional Chinese medicine, is affected by its host plant. The researchers used metabolomics to investigate the influence of host plants and environmental factors on mistletoe's medicinal qualities. The results show that both host plants an...
SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateJun 8, 2022
Researchers at Nagoya University developed a chemical-only process to create customized mRNA vaccines, offering an inexpensive and large-scale production of mRNA. The new method allows for precise molecular design and stable mRNA with improved translational activity.
SourceNagoya University·JournalACS Chemical Biology·DateJun 7, 2022
Researchers have identified glycans in mucus that can prevent Candida albicans from causing infection. These molecules can be used to develop new antifungal medicines or make disease-causing fungus more susceptible to existing drugs.
SourceMassachusetts Institute of Technology·JournalNature Chemical Biology·DateJun 6, 2022
Meta Quest 3 512GB
Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.
A study published in eLife found that high-intensity interval training increases the production of proteins essential for energy metabolism and muscle contractions, as well as alters key metabolic proteins through acetylation. These changes may contribute to improved metabolic health.
Researchers have developed a new carbon capture method using sponge-like materials that can trap CO2 without degrading over time. The materials are made from sugar and low-cost alkali metal salts, making them a potentially cost-effective solution for reducing coal-fired power plant emissions.
SourceCornell University·JournalAngewandte Chemie·DateMay 23, 2022
Researchers at Rutgers University have created an automated tool to monitor biologic drugs during production, allowing for real-time quality control and enabling the production of biosimilars. The N-GLYcanyzer system can track changes in protein glycosylation and detect potential issues, improving drug safety and efficacy.
SourceRutgers University·JournalAnalytical Chemistry·DateMay 18, 2022
Researchers study the sea-surface microlayer, a biogeochemical reactor where organisms adapt to harsh conditions like UV radiation and fluctuating temperatures. The team aims to understand biological, chemical, and physical interactions in this thin layer, influencing global climate.
Apple MacBook Pro 14-inch (M4 Pro)
Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.
Researchers have discovered that a human enzyme converts marine sponge chemicals into cell-killing compounds, which could lead to the development of new cancer and infection treatments. The findings identified an untapped toolbox of natural and synthetic compounds that can be converted by widespread enzymes into potentially useful drugs.
Scientists at Scripps Research developed a new method called CATCH to image where drugs bind to their targets across different tissues and with higher precision than ever before. This technique allows for better understanding of why one drug is more potent or has a particular side effect compared to another.
SourceScripps Research Institute·JournalCell·DateApr 29, 2022
A mathematical model reveals that spontaneous symmetry breaking in chemical reactions leads to homochirality, optimizing energy harvesting from the environment. This phenomenon could explain how life developed on primordial Earth and has implications for the synthesis of chiral drug molecules.
SourceInstitute for Basic Science·JournalNature Communications·TypeComputational simulation/modeling·DateApr 26, 2022
A new technology developed by KIT researchers uses polymer membranes coated with titanium dioxide to break down steroid hormones and other micropollutants in wastewater. The process is efficient, removing hormone concentrations close to the World Health Organization's drinking water guideline.
SourceKarlsruher Institut für Technologie (KIT)·JournalNature Nanotechnology·TypeExperimental study·DateApr 22, 2022
Researchers at Aarhus University have developed improved DNA nanostructures that can assemble biomolecules with multiple functions, increasing the effectiveness of cancer treatment. The new structures are more stable, non-toxic, and immune system-friendly than previous versions.
SourceAarhus University·JournalAngewandte Chemie International Edition·TypeExperimental study·DateApr 20, 2022
Sky & Telescope Pocket Sky Atlas, 2nd Edition
Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.
A novel inhibitor has been discovered that stalls a critical enzyme inside tumour cells, locking them in place and preventing invasion into healthy tissue. The findings hold promise for the development of metastasis-blocking agents.
SourceUniversity of Konstanz·JournalCell Chemical Biology·DateApr 20, 2022
Researchers create complex mixtures of biomolecules that spontaneously form self-organized patterns in response to environmental changes. This breakthrough bridges the complexity gap between chemistry and biology.
SourceAdvanced Science Research Center, GC/CUNY·JournalChem·TypeExperimental study·DateApr 12, 2022
Researchers developed a novel protocol for the direct synthesis of amides via heterogeneous manganese oxide catalyzed successive cleavage and amidation of C-C bonds in alcohols. The method features good functional-group tolerance, cost-effective and recyclable catalyst, and broad substrate scope.
SourceDalian Institute of Chemical Physics, Chinese Academy Sciences·JournalChem·TypeCommentary/editorial·DateApr 1, 2022
Sky-Watcher EQ6-R Pro Equatorial Mount
Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.
Researchers use DNA to program metal nanoparticles to assemble into new configurations, resulting in the discovery of three new crystalline phases. The approach enables symmetry breaking and creation of complex colloidal crystal structures with unique optical and catalytic properties.
SourceDOE/Argonne National Laboratory·JournalNature Materials·DateMar 31, 2022
Researchers developed long-lived biological computers using RNA, which can persist inside cells. Unlike DNA-based devices, these RNA circuits are dependable and versatile, enabling continuous production in living cells.
SourceNational Institute of Standards and Technology (NIST)·JournalScience Advances·DateMar 23, 2022
Researchers have described a pioneering chemical technique that can degrade proteins implicated in cancer, potentially increasing the potency and selectivity of new and existing drugs. This technique, known as proteolysis targeting chimeras (PROTACs), targets specific structures within cancerous cells to reduce harmful side effects.
SourceUniversity of Leicester·JournalJournal of Medicinal Chemistry·TypeExperimental study·DateMar 17, 2022
SAMSUNG T9 Portable SSD 2TB
SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.
Researchers have designed a fast-acting injectable insulin based on the venom of the Conus kinoshitai marine snail, which doesn't form clusters like human insulin. The new hybrid insulin holds promise for better diabetes control with faster action and reduced clustering.
SourceUniversity of Utah Health·JournalNature Chemical Biology·TypeExperimental study·DateMar 15, 2022
Researchers found that sugar-decorated proteins in mucus can bind to the coronavirus, keeping it from infecting cells. This discovery may explain why SARS-CoV-2 is more likely to spread through airborne droplets rather than surface transmission.
SourceAmerican Chemical Society·JournalACS Central Science·DateMar 2, 2022
Scientists have developed a new computational tool that mimics the processes of natural selection, producing proteins for medicinal and household uses. This innovation reduces the time required for laboratory evolution from months or years to just days.
SourceCurtin University·JournalNature Chemical Biology·TypeRandomized controlled/clinical trial·DateFeb 24, 2022
AmScope B120C-5M Compound Microscope
AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.
Researchers discovered that gut bacteria can awaken dormant viruses by producing colibactin, leading to cell-killing infections. This finding suggests a possible link between colibactin-producing bacteria and cancer, potentially benefiting the bacteria's own survival.
SourceHoward Hughes Medical Institute·JournalNature·DateFeb 23, 2022
Researchers at University of Texas at Austin create first-ever biologically authentic computer model of HIV-1 virus liposome, shedding light on replication and infectivity. The study reveals key characteristics of the liposome's asymmetry and its role in shaping macroscopic properties.
SourceUniversity of Texas at Austin, Texas Advanced Computing Center·JournalPLOS Computational Biology·TypeComputational simulation/modeling·DateFeb 23, 2022
Researchers found that kitchen sponges provide an optimal environment for microbial diversity by mimicking the separation and communal spaces found in healthy soil. This complex structure supports both solitary and diverse bacterial communities, leading to higher biodiversity levels.
SourceDuke University·JournalNature Chemical Biology·TypeExperimental study·DateFeb 17, 2022
A recent study by ITQB NOVA scientists uncovered the crucial role of a small marker protein, DsrD, in increasing metabolic activity for sulfate respiration. The findings suggest that DsrD acts as an allosteric activator of the DsrAB dissimilatory sulfite reductase, enhancing energy efficiency in microbial metabolism.
SourceInstituto de Tecnologia Química e Biológica António Xavier da Universidade NOVA de Lisboa ITQB NOVA·JournalProceedings of the National Academy of Sciences·DateFeb 17, 2022
GoPro HERO13 Black
GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.
A new protein group has been identified that functions as a switch to regulate biological activity, found in all domains of life and essential for cellular activities such as gene expression and metabolism. The discovery opens up new possibilities for the development of novel drugs targeting these switches.
SourceUniversity of Göttingen·JournalNature Chemical Biology·TypeExperimental study·DateFeb 16, 2022
A University of Oklahoma chemist is engineering a sustainable method for producing valuable compounds found in nature, such as cannabinoids and squalenes, using enzymes and E. coli. This approach avoids the environmental and economic challenges associated with traditional plant-based methods.
A newly developed decoy protein has been found to be highly effective in preventing death and lung damage in humanized animal models of severe COVID-19 disease. The treatment works by competing for the spike protein of SARS-CoV-2, thereby neutralizing the virus before it can bind and enter cells.
SourceUniversity of Illinois Chicago·JournalNature Chemical Biology·TypeExperimental study·DateJan 19, 2022
Rigol DP832 Triple-Output Bench Power Supply
Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.
Scientists develop a sensitive electrochemical detector using cerium oxide nanozyme to identify organophosphate pesticides in plants. The method provides an unprecedented wider linear range and a detection limit of 0.06 mmol/L, making it suitable for detecting trace amounts of pesticide residues.
SourceCactus Communications·JournalJournal of Pharmaceutical Analysis·TypeExperimental study·DateJan 19, 2022
Researchers have created a new, simpler way to fabricate SERS nanostructures with superior stability and performance at low cost. By using a heat-resistant polymer called polyimide (PI), they can produce nanosurfaces with nanopillars that enhance signal intensity for efficient chemical detection. The new fabrication method has the pote...
SourcePusan National University·JournalSensors and Actuators B Chemical·TypeExperimental study·DateJan 17, 2022
Gladstone Institutes researchers have pioneered a new method to edit genes in human cells using retrons, which can produce abundant copies of template DNA from inside cells. The optimized system has shown improved efficiency and precision compared to current approaches.
SourceGladstone Institutes·JournalNature Chemical Biology·DateJan 5, 2022
Researchers discovered that bacteria use an ancient molecule called polyphosphate to silence problematic genetic elements, similar to heterochromatin in eukaryotes. This process helps protect the bacterial cell from harm and could enable scientists to develop new antibiotics.
SourceMichigan Medicine - University of Michigan·JournalScience Advances·DateJan 5, 2022
GQ GMC-500Plus Geiger Counter
GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.
Scientists created macroscopic living functional materials by adhering bacteria together, demonstrating improved mechanical properties and processability. The material can also self-heal within minutes and degrade organophosphate pesticides.
SourceChinese Academy of Sciences Headquarters·JournalNature Chemical Biology·DateJan 4, 2022
The study found that cell nuclei become less solid and more liquid-like as they differentiate, allowing them to commit to a specific path. This change is linked to the aggregation of chromatin and fine-tunes how responsive the nucleus is to external forces.
Scientists developed a breakthrough fabrication process for microneedle arrays capable of administering protein-based drugs without damaging the skin. The microneedles offer several advantages, including being painless and easy to dispose of.
SourceJapan Advanced Institute of Science and Technology·JournalBiomacromolecules·DateDec 27, 2021
Researchers at Washington University in St. Louis described for the first time the structure of CcsBA, a protein that transports heme and attaches it to cytochromes. The study revealed two conformational states of CcsBA, allowing scientists to characterize the enzyme mechanism.
SourceWashington University in St. Louis·JournalNature Chemical Biology·TypeExperimental study·DateDec 20, 2021
Scientists at Tokyo University of Science have developed a novel polymer-based hydrogel that can prevent postoperative pancreatic fistulae, a frequent complication of pancreatic surgery. The Exceval hydrogel shows great promise for clinical applications due to its adjustable properties and high absorption abilities.
SourceTokyo University of Science·JournalPolymers for Advanced Technologies·TypeExperimental study·DateDec 7, 2021
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.
A new approach has been developed to identify proteins affected by pollutants and chemicals, allowing for early detection of harmful biological effects. The method, called PISA, can be used to study the interactions between chemicals and proteins, revealing potential toxicity pathways.
SourceLinköping University·JournalJournal of Proteomics·TypeExperimental study·DateNov 29, 2021
Researchers in Japan have designed the first de novo-designed peptides that can form artificial nanopores to identify and enable single molecule-sorting of genetic material in a lipid membrane. The peptides can detect specific molecules, including DNA, and have the potential to mimic natural proteins' ability to detect specific proteins.
SourceTokyo University of Agriculture and Technology·JournalNature Nanotechnology·DateNov 24, 2021