Articles tagged with Hydrogels
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Researchers have developed a hydrogel-based carrier that can deliver siRNAs directly to tumors, overcoming the challenge of rapid degradation and limited cellular entry. This innovative technology has the potential to improve the effectiveness of siRNA-based cancer treatments and enable more efficient delivery of biologics.
Researchers have developed a self-assembling peptide hydrogel that increases blood vessel regrowth and neuronal survival in rats with traumatic brain injuries. The treatment also improves the survival of brain cells and shows signs of new blood vessel formation.
Researchers developed a CRISPR-responsive hydrogel system that can be programmed to release compounds, nanoparticles, or live cells in response to specific DNA targets. The system's sensitivity and versatility make it suitable for various biomedical applications, including tissue engineering, bio-electronics, and biosensing.
Researchers from UCLA School of Dentistry developed a new hydrogel that promotes tissue repair and regeneration, inducing stem cell migration to enhance bone healing. The clay-enhanced hydrogel has a more porous structure, improving its ability to deliver cells to defective areas.
The Korea Institute of Science and Technology developed a transfer-printing technology for creating high-performance sensors on diverse shapes and structures. The KIST team used hydrogel and nano ink to easily create electrodes, overcoming limitations in traditional transfer printing processes.
Researchers at Kazan Federal University and Fox Chase Cancer Center have developed a safer alternative to existing drainage methods for malignant pleural effusion. The new hydrogel-based approach improved patient outcomes by stalling health deterioration and increasing survival rates by 55% compared to standard therapy.
Researchers at UMass Lowell have discovered that eggshell particles can increase bone cells' ability to grow and harden, potentially resulting in faster healing. The technique uses crushed eggshells in a hydrogel mixture to support bone growth, offering a sustainable alternative to traditional methods.
Researchers developed a process to release multiple active ingredients in sequence under conditions similar to the human body, using hydrogels and artificial DNA. The particles are released one by one, with each stage triggered by the previous release.
Researchers have developed a double-duty hydrogel that both kills bacteria and promotes bone regrowth using lysostaphin and BMP-2. This breakthrough therapy shows promise in treating orthopedic bone infections with fewer surgeries and accelerated healing.
Three researchers win IADR Innovation in Oral Care Awards for developing novel treatments for craniofacial bone defects and periodontitis, with focus on growth-factor-free approaches.
Researchers have developed a process for 3D printing biological tissues without scaffolds using stem cells in a hydrogel bead bath. The printed cells form stable connections and mature into functional tissues, offering potential applications in tissue engineering and regenerative medicine.
Researchers created a hydrogel-based adhesive inspired by snails' mucus, combining strength and reversibility. The PHEMA gel achieves adhesive strengths comparable to superglues, with 'shape adaptation and memory' properties.
Researchers have created a new type of hydrogel that can grow new tissue to heal wounds, eliminating the need for external growth factors. The hydrogels are made with biomolecules anchored in crosslinkers and can be mixed at room temperature.
A team of researchers has developed a nano-sized hydrogel that can scavenge nitric oxide and effectively treat rheumatoid arthritis. The hydrogel was shown to be more effective than current therapeutic drugs in suppressing the onset of the disease, with minimal side effects.
A Texas A&M research team has developed a new class of hydrogel bioinks loaded with therapeutic proteins, which can be used for precise deposition of protein therapeutics in 3D. The bioink formulation has unique shear-thinning properties that allow it to stay in place after injection, making it suitable for 3D bioprinting applications.
A team of scientists at Shinshu University used a newly customized tool to study hydrogel microspheres, observing structural differences that were previously unexplained. The study reveals that the method of production greatly affects the structure and behavior of thermoresponsive microgels.
Researchers are developing a top-down lithography method to create complex tissues and their anatomical microstructures. This approach uses light sheet illumination and special hydrogels to form branched chain structures that serve as a matrix for cell colonization.
Researchers create molecular tethers to attach proteins to scaffolds, allowing for reversible functionalization while preserving activity. This approach enables precise control of protein signals, promoting tissue growth and differentiation.
Scientists have developed a technique to produce highly ordered particle layers using tiny gold particles encapsulated in soft polymer beads. The resulting ultrathin superlattices exhibit collective resonances when excited by light, enabling potential applications in optoelectronics and nanophotonics.
A study directly compares chondrogenic induction by hydrogels containing MSCs as either single cell suspensions or 100-500-cell micropellets. The results show that micropellet-encapsulated MSCs outperform single cells in cartilage regeneration, providing guidance for future cartilage engineering efforts.
Researchers at Johns Hopkins Medicine have created a synthetic soft tissue substitute that encourages growth of new tissue and blood vessels. The material, well-tolerated and retaining its shape, may lessen the need for implants or grafts in reconstructive surgeries.
Researchers have developed a method to print complex vascular networks in biocompatible hydrogels using food dye #5, mimicking the architecture of biological tissues. This breakthrough has significant implications for tissue engineering and organ transplantation.
Researchers created hydrogels that mimic muscle properties through mechanical training, producing strong, soft, and fatigue-resistant materials for medical implants and engineering applications. The trained hydrogels demonstrate improved tensile strength, soft flexibility, and high water content.
Researchers at Johns Hopkins Medicine developed a gel-like platform that activates and multiplies cancer-fighting T-cells, outperforming traditional methods in mouse experiments. The artificial lymph node technology has potential for regenerative immunology-based therapy.
Researchers develop a new polymer that can expand and contract in response to light, lifting a weight with minimal stimulation. The material has potential applications in biomedical fields, such as drug-delivery devices or artificial muscles.
Scientists have created a hydrogel matrix whose stiffness can be reversibly tuned using light, enabling the investigation of how cells respond to dynamic changes in their environment. The matrix has potential applications in cancer immunotherapy and understanding cell migration patterns.
A new thixogel called CNF hydrogel has been developed by SUTD researchers, offering improved cell encapsulation and delivery. The hydrogel combines the benefits of both solid and liquid forms, providing a protective environment for cells while conforming to host tissue geometry.
Brown University researchers create modular hydrogel components that can bend, twist, or stick together in response to treatment with certain chemicals. The components are designed for various
Researchers at UT Austin developed a solar-powered moisture harvester that captures and cleans water from the air using hydrogels. The system can produce up to 50 liters of clean water per kilogram of hydrogel, making it a promising solution for disaster situations, water crises, or poverty-stricken areas.
Researchers at UNH have developed a new hydrogel that deactivates matrix metalloproteinases (MMPs) responsible for corneal melting by removing zinc ions. This localized treatment avoids side effects common with existing MMP inhibitors, paving the way for a potential contact lens therapy.
Researchers discovered the lobster membrane is surprisingly tough and stretchy, making it a potential guide for designing flexible body armor. The membrane's layered structure, similar to plywood, provides exceptional strength and resistance to scratches and cuts, outperforming industrial rubber composites.
Dr. Kyungsuk Yum develops bioinspired 3D materials that can form complex shapes and motions in response to external signals. His research has potential applications in bioinspired soft robotics, biomedical devices, tissue engineering, and artificial muscles.
Researchers at Linköping University created a hydrogel that mimics the natural environment of cells, allowing for the growth of human liver cells on microchips. This innovation has the potential to simplify early stages of drug development and replace animal experiments.
Hokkaido University researchers have developed a strategy to fabricate materials that become stronger in response to mechanical stress. By employing 'double-network hydrogels,' they were able to create soft, yet tough materials that can adapt and strengthen based on surrounding conditions.
Researchers designed an ingestible pill that quickly inflates to track stomach temperature for 30 days, then deflates using calcium solution. The hydrogel-based design is softer and longer-lasting than current sensors, inspired by the pufferfish's defense mechanism.
A team of researchers has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm after experiencing a heart attack. They have also discovered a drug candidate that can block this pathway.
Researchers have developed an adhesive that can strongly adhere to wet materials like hydrogel and living tissue, and be easily detached with specific frequencies of light. This technology has the potential to enable painless detachment of wound dressings and transdermal drug delivery devices.
Researchers at UPV/EHU have created a starch and graphene hydrogel with electrical and antibacterial properties suitable for neural interfaces. The hydrogel was produced using click chemistry and is stable in an aqueous medium due to the addition of salvia extracts.
Researchers at KAUST developed a device that can capture its own weight in water from fresh air and release it when warmed by sunlight. The device uses deliquescent salt and a polymer hydrogel to absorb moisture from the air, which is then released continuously with the help of carbon nanotubes.
Researchers at EPFL have developed a biocompatible hydrogel that naturally adheres to cartilage and the meniscus, eliminating the need for special membranes and sutures. The composite double-network hydrogel has shown superior adhesive properties and is poised to revolutionize treatment for soft tissue injuries.
Researchers at the University of New Hampshire have developed a new, macroporous hydrogel that facilitates faster wound healing by allowing cells to migrate into the wound. The injectable formulation also enables slow release of protein drugs, such as platelet-derived growth factor, to aid in the healing process.
Kyungsuk Yum and his doctoral student Amirali Nojoomi developed a process to program 2-D hydrogels for space- and time-controlled swelling and shrinking, enabling the formation of complex 3-D shapes and motions. The technology has potential applications in bioinspired soft robotics and artificial muscles.
Researchers are developing a biodegradable and bioactive hydrogel material that can be injected into the heart to promote cardiac repair after a heart attack. The goal is to significantly increase stem cell recruitment, accelerate cardiac repair and improve cardiac function.
Scientists develop peptide hydrogel that stimulates new blood vessel and dental pulp growth in teeth after root canals. The material aims to preserve more of the existing dental pulp and help grow new tissue, making the procedure less invasive.
Researchers at Georgia Institute of Technology developed a molecular matrix that effectively delivers muscle satellite cells to injured muscle tissue, promoting healing and protection from immune reactions. The hydrogel therapy has potential to treat muscular dystrophy patients, including those with Duchene muscular dystrophy.
A composite hydrogel and MXene material offers unparalleled stretchability, self-healing, and strain sensitivity, opening doors to innovative applications such as wearable electronics, biodegradable patches, and biosensing technologies.
Researchers from SUTD and HUJI develop highly stretchable, UV-curable hydrogels suitable for high-resolution 3D printing. These hydrogels enable the fabrication of complex geometries and high-stretchability structures.
Researchers developed a novel gel-like material that effectively dehumidifies ambient air while harnessing the moisture in the air for various applications. The hydrogel can absorb water from surrounding air more than 2.5 times its weight and performs at least eight times better than commercial drying agents.
Researchers use hydrogels to safely remove pressure-sensitive tapes from paper artworks without solvents, preserving the underlying artwork. The technique reveals hidden inscriptions like Michelangelo's 'di mano di Michelangelo' on a 16th-century drawing.
Researchers at the University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues. The material can generate multiple types of human soft tissues, including skin, skeletal muscles, blood vessels, and heart muscles.
Scientists at Brigham and Women's Hospital have created a hydrogel that responds to increased disease activity during flares, releasing drugs to alleviate symptoms. The technology has shown promise in preclinical models and could provide a new treatment option for patients with arthritis.
A team of researchers from Texas A&M University has developed an injectable bandage using a gelling agent commonly used in pastries, which can stop bleeding and promote wound healing. The injectable hydrogels are made with kappa-carrageenan and nanosilicates to form a controlled release of therapeutics.
Researchers at the University of Texas at Austin have developed a new technology using combined gel-polymer hybrid materials to produce clean drinking water from any source. The system uses ambient solar energy to power evaporation, reducing energy consumption and increasing water volume.
Engineered 3D morphogen gradients in hydrogels direct human salivary gland stem/progenitor cell differentiation into ductal and acinar cell phenotypes. Growth factor gradients support salivary gland cell motility and can serve as instructive matrices for tissue engineering.
Researchers at Rice University have developed a hydrogel that significantly accelerates wound healing in genetically diabetic rodents, promoting tissue growth and regeneration. The study's findings suggest that the hydrogel's cellular infiltration enhances wound closure rates, providing hope for improved treatment of diabetic ulcers.
Scientists have developed tiny, implantable sensors that can detect various body chemistries without triggering an immune response. The devices are being marketed in Europe and are expected to receive US approval, with potential applications including monitoring oxygen levels in patients with peripheral artery disease.
Researchers discovered that a hydrogel developed by the Rice University lab exhibits significant therapeutic properties, rapidly infiltrating host cells and promoting healing. The hydrogel can be delivered through a syringe and degrades over six weeks, leaving behind healthy tissue.
A Lehigh University professor has received a prestigious NSF CAREER Award to explore the role of human mesenchymal stem cells in remodeling hydrogel materials for wound healing. Her research aims to develop new biomaterials with optimal properties for tissue regeneration and structural integrity.
A new slow-release hydrogel has been developed to aid immunotherapy for cancer, providing a continuous dose of immunotherapy drugs to activate the immune system. The hydrogel, called STINGel, was tested in lab cultures and in vivo trials, showing promise in killing cancer cells and preventing further implantation of cancer cells.
Researchers have developed a new method to chemically bond multiple soft materials without sacrificing their properties. The technique allows for manufacturing of more complex soft machines, including wearable devices and flexible electronics.