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Hydrogel mimics human brain with memorizing and forgetting ability

Researchers at Hokkaido University developed a hydrogel that mimics the human brain's dynamic memory function, encoding information that fades with time depending on intensity. The hydrogel's memory system can be programmed by temperature and learning time, allowing for stable memory establishment and controlled forgetting processes.

SourceHokkaido University·JournalProceedings of the National Academy of Sciences·DateJul 27, 2020

New bioink for cell bioprinting in 3D

A research group at Linköping University has developed a dynamic bioink that allows cells to survive and thrive during 3D printing. The bioink's properties can be modified as required, enabling the creation of tissue-mimicking materials with tailored functionalities.

SourceLinköping University·JournalBiofabrication·DateJul 13, 2020

Lighting the path for cells

Researchers at ETH Zurich have developed a new method to distribute bioactive molecules in three-dimensional space, allowing them to guide the growth of nerve fibers and other biological processes. This innovation has potential benefits for medicine, including improving recovery from neural injuries.

SourceETH Zurich·JournalAdvanced Materials·DateMay 12, 2020

Active droplets

Researchers created 'active droplets' that release drugs at a constant rate over several days, reducing the risk of overdose. The droplets are stable for longer due to hydrolysis protection and can be loaded with varying doses.

SourceTechnical University of Munich (TUM)·JournalMaterials Horizons·DateFeb 20, 2020

Structual color barcode micromotors for multiplex biosensing

Researchers at Southeast University have developed a novel kind of microtort with stable structural color for multiplex assays. These micromotors can efficiently accelerate mixing speed and increase probe-target interactions, leading to faster and more sensitive detection. The unique structural color coding allows for simultaneous mult...

SourceScience China Press·JournalNational Science Review·DateJan 16, 2020

Lights on for germ-free wound dressings

Researchers have introduced a gel that is activated by red light to produce reactive oxygen compounds effectively killing bacteria and fungi. The hydrogel combines photodynamic antimicrobial chemotherapy with fully synthetic properties, overcoming previous biocompatibility issues.

SourceWiley·JournalAngewandte Chemie International Edition·DateJan 16, 2020

Hydrogels control inflammation to help healing

Researchers have developed injectable hydrogels that can tune the body's inflammatory response, promoting or reducing inflammation as needed. The study found that positively charged hydrogels triggered stronger responses for wound-healing and cancer treatment, while negatively charged gels were better suited for drug delivery.

SourceRice University·JournalBiomaterials·DateDec 16, 2019

Getting glued in the sea

Researchers at Hokkaido University developed adhesives inspired by mussels that utilize electrostatic interactions to stick to negatively charged surfaces in saltwater. The adhesiveness was largely thanks to the interaction between positively charged residues on the polymers and the negatively charged surfaces.

SourceHokkaido University·JournalNature Communications·DateNov 12, 2019

New 3D printing technique for biomaterials

Researchers at the University of Birmingham have developed a new 3D printing technique called Suspended Layer Additive Manufacturing (SLAM) that can create soft biomaterials for repairing body defects. The technique uses a polymer-based hydrogel with self-healing properties, allowing for precise detail and support without sagging.

SourceUniversity of Birmingham·JournalAdvanced Functional Materials·DateOct 4, 2019

High-tech gel aids delivery of drugs

Researchers have developed a hydrogel-based carrier that can deliver siRNAs directly to tumors, overcoming the challenge of rapid degradation and limited cellular entry. This innovative technology has the potential to improve the effectiveness of siRNA-based cancer treatments and enable more efficient delivery of biologics.

SourceUniversity of Illinois Chicago·JournalScience Advances·DateAug 28, 2019

CRISPR-responsive hydrogel system offers programmable approach to smart biomaterials

Researchers developed a CRISPR-responsive hydrogel system that can be programmed to release compounds, nanoparticles, or live cells in response to specific DNA targets. The system's sensitivity and versatility make it suitable for various biomedical applications, including tissue engineering, bio-electronics, and biosensing.

Uncovering microgel mysteries

A team of scientists at Shinshu University used a newly customized tool to study hydrogel microspheres, observing structural differences that were previously unexplained. The study reveals that the method of production greatly affects the structure and behavior of thermoresponsive microgels.

SourceShinshu University·JournalAngewandte Chemie International Edition·DateMay 30, 2019

Traffic control of cells

Scientists have created a hydrogel matrix whose stiffness can be reversibly tuned using light, enabling the investigation of how cells respond to dynamic changes in their environment. The matrix has potential applications in cancer immunotherapy and understanding cell migration patterns.

SourceUniversity of Freiburg·JournalAdvanced Materials·DateMar 25, 2019