Articles tagged with Hydrogels
Dr. Kyungsuk Yum develops bioinspired 3D materials that can form complex shapes and motions in response to external signals. His research has potential applications in bioinspired soft robotics, biomedical devices, tissue engineering, and artificial muscles.
Researchers at Linköping University created a hydrogel that mimics the natural environment of cells, allowing for the growth of human liver cells on microchips. This innovation has the potential to simplify early stages of drug development and replace animal experiments.
Hokkaido University researchers have developed a strategy to fabricate materials that become stronger in response to mechanical stress. By employing 'double-network hydrogels,' they were able to create soft, yet tough materials that can adapt and strengthen based on surrounding conditions.
Researchers designed an ingestible pill that quickly inflates to track stomach temperature for 30 days, then deflates using calcium solution. The hydrogel-based design is softer and longer-lasting than current sensors, inspired by the pufferfish's defense mechanism.
A team of researchers has identified a genetic pathway that causes some individuals to develop an abnormal heart rhythm after experiencing a heart attack. They have also discovered a drug candidate that can block this pathway.
Researchers have developed an adhesive that can strongly adhere to wet materials like hydrogel and living tissue, and be easily detached with specific frequencies of light. This technology has the potential to enable painless detachment of wound dressings and transdermal drug delivery devices.
Researchers at UPV/EHU have created a starch and graphene hydrogel with electrical and antibacterial properties suitable for neural interfaces. The hydrogel was produced using click chemistry and is stable in an aqueous medium due to the addition of salvia extracts.
Researchers at KAUST developed a device that can capture its own weight in water from fresh air and release it when warmed by sunlight. The device uses deliquescent salt and a polymer hydrogel to absorb moisture from the air, which is then released continuously with the help of carbon nanotubes.
Researchers at EPFL have developed a biocompatible hydrogel that naturally adheres to cartilage and the meniscus, eliminating the need for special membranes and sutures. The composite double-network hydrogel has shown superior adhesive properties and is poised to revolutionize treatment for soft tissue injuries.
Researchers at the University of New Hampshire have developed a new, macroporous hydrogel that facilitates faster wound healing by allowing cells to migrate into the wound. The injectable formulation also enables slow release of protein drugs, such as platelet-derived growth factor, to aid in the healing process.
Kyungsuk Yum and his doctoral student Amirali Nojoomi developed a process to program 2-D hydrogels for space- and time-controlled swelling and shrinking, enabling the formation of complex 3-D shapes and motions. The technology has potential applications in bioinspired soft robotics and artificial muscles.
Researchers are developing a biodegradable and bioactive hydrogel material that can be injected into the heart to promote cardiac repair after a heart attack. The goal is to significantly increase stem cell recruitment, accelerate cardiac repair and improve cardiac function.
Scientists develop peptide hydrogel that stimulates new blood vessel and dental pulp growth in teeth after root canals. The material aims to preserve more of the existing dental pulp and help grow new tissue, making the procedure less invasive.
Researchers at Georgia Institute of Technology developed a molecular matrix that effectively delivers muscle satellite cells to injured muscle tissue, promoting healing and protection from immune reactions. The hydrogel therapy has potential to treat muscular dystrophy patients, including those with Duchene muscular dystrophy.
A composite hydrogel and MXene material offers unparalleled stretchability, self-healing, and strain sensitivity, opening doors to innovative applications such as wearable electronics, biodegradable patches, and biosensing technologies.
Researchers from SUTD and HUJI develop highly stretchable, UV-curable hydrogels suitable for high-resolution 3D printing. These hydrogels enable the fabrication of complex geometries and high-stretchability structures.
Researchers developed a novel gel-like material that effectively dehumidifies ambient air while harnessing the moisture in the air for various applications. The hydrogel can absorb water from surrounding air more than 2.5 times its weight and performs at least eight times better than commercial drying agents.
Researchers use hydrogels to safely remove pressure-sensitive tapes from paper artworks without solvents, preserving the underlying artwork. The technique reveals hidden inscriptions like Michelangelo's 'di mano di Michelangelo' on a 16th-century drawing.
Researchers at the University of Texas at Arlington have developed a highly elastic biodegradable hydrogel for bio-printing of materials that mimic natural human soft tissues. The material can generate multiple types of human soft tissues, including skin, skeletal muscles, blood vessels, and heart muscles.
Scientists at Brigham and Women's Hospital have created a hydrogel that responds to increased disease activity during flares, releasing drugs to alleviate symptoms. The technology has shown promise in preclinical models and could provide a new treatment option for patients with arthritis.
Researchers at the University of Texas at Austin have developed a new technology using combined gel-polymer hybrid materials to produce clean drinking water from any source. The system uses ambient solar energy to power evaporation, reducing energy consumption and increasing water volume.
A team of researchers from Texas A&M University has developed an injectable bandage using a gelling agent commonly used in pastries, which can stop bleeding and promote wound healing. The injectable hydrogels are made with kappa-carrageenan and nanosilicates to form a controlled release of therapeutics.
Engineered 3D morphogen gradients in hydrogels direct human salivary gland stem/progenitor cell differentiation into ductal and acinar cell phenotypes. Growth factor gradients support salivary gland cell motility and can serve as instructive matrices for tissue engineering.
Researchers at Rice University have developed a hydrogel that significantly accelerates wound healing in genetically diabetic rodents, promoting tissue growth and regeneration. The study's findings suggest that the hydrogel's cellular infiltration enhances wound closure rates, providing hope for improved treatment of diabetic ulcers.
Scientists have developed tiny, implantable sensors that can detect various body chemistries without triggering an immune response. The devices are being marketed in Europe and are expected to receive US approval, with potential applications including monitoring oxygen levels in patients with peripheral artery disease.
Researchers discovered that a hydrogel developed by the Rice University lab exhibits significant therapeutic properties, rapidly infiltrating host cells and promoting healing. The hydrogel can be delivered through a syringe and degrades over six weeks, leaving behind healthy tissue.
A Lehigh University professor has received a prestigious NSF CAREER Award to explore the role of human mesenchymal stem cells in remodeling hydrogel materials for wound healing. Her research aims to develop new biomaterials with optimal properties for tissue regeneration and structural integrity.
A new slow-release hydrogel has been developed to aid immunotherapy for cancer, providing a continuous dose of immunotherapy drugs to activate the immune system. The hydrogel, called STINGel, was tested in lab cultures and in vivo trials, showing promise in killing cancer cells and preventing further implantation of cancer cells.
Researchers have developed a new method to chemically bond multiple soft materials without sacrificing their properties. The technique allows for manufacturing of more complex soft machines, including wearable devices and flexible electronics.
Researchers developed an electric eel-inspired device that produced 110 volts from gels filled with varying strengths of salt water, leveraging ion gradients across hydrogels. The team hopes to increase the current and develop a power source for implantable devices utilizing existing human body ionic gradients.
Researchers at Rutgers University have created a 4D-printed shape-shifting smart gel that can morph over time and temperatures change. The gel can provide structural rigidity in organs like the lungs and create new applications in soft robotics, biomedical devices, and scaffolds for cell growth.
Researchers at UNIST created a new type of underwater adhesive that is stronger than natural biological glues used by mussels. The hydrogel-based adhesive exhibits strong adhesion under wet conditions due to reversible interlocking between reconfigurable microhook arrays.
Scientists at the University of Washington have developed a new biomaterial-based delivery system that releases therapeutics in response to specific physiological conditions. The system uses 'logic gates' programmed with Boolean logic to open and release cargo only when certain environmental cues are met.
Researchers developed a molecular printing technique, 3DEAL, to create complex hydrogel environments with controlled chemical composition. This allows for the design of new drug screening platforms and tissue-engineered constructs with spatially controlled gradients or patterns.
Researchers from NTU Singapore and CMU have developed a technique to direct the growth of hydrogel to mimic plant or animal tissue structure and shapes. The team's findings suggest new applications in tissue engineering and soft robotics, where hydrogel is commonly used.
Researchers have developed soft power cells that mimic the electric eel's ability to generate high-voltage electricity while consuming low current. The cells are made of hydrogel and salt and could potentially power implantable or wearable devices without toxicity or frequent recharging.
Scientists at USC have developed a temperature-sensitive gel that can seal eye injuries, allowing for faster treatment and reducing the risk of complications. The reversible seal can be easily removed with cool water, making it a promising solution for treating ocular injuries on the battlefield.
MIT engineers have devised a 3D printing technique that uses live bacteria cells to create interactive structures. The team printed a 'living tattoo' with branches that light up in response to different chemical stimuli, demonstrating the potential for wearable sensors and interactive displays.
A team of ETH researchers created a novel 3D printing platform that utilizes living matter to produce mini biochemical factories with various properties. The platform uses bacteria-containing ink to create objects with specific characteristics, such as biodegradable materials and sensors for toxic substances.
A team of biomedical engineers has developed a photocrosslinkable, thermoreversible type-I collagen bioink for 3D printing of scaffolds. The bioink allows for spatially controlled cross-linking and can be used to print scaffolds with macroscale features, facilitating tissue engineering and regenerative medicine applications.
Researchers created a synthetic material that combines the strengths of Kevlar with polyvinyl alcohol to mimic natural cartilage's properties. The new material boasts the same mechanism as natural cartilage, releasing water under stress and recovering by absorbing it later.
Scientists have successfully created tiny protein-based gelatin-like clumps called hydrogels inside living cells using a novel technique. This breakthrough advances research into the suspected contributions of hydrogels to human diseases, such as neurodegenerative disorders.
Researchers at Penn State create artificial system using DNA-laced hydrogel that releases signaling protein in response to chemical signal. The system, which uses aptamers and double-stranded helical molecules of DNA, can repeat the sequence, releasing proteins until there are no more to release.
Researchers created synthetic hydrogels that allowed human intestinal cells to grow and differentiate in a 3D environment, forming normal tissue structures. The hydrogels can be easily modified to support various cell types, offering a promising approach for treating gut injuries and potentially other organ damage.
Researchers at Scripps Research Institute have developed a method for creating modified DNA-based hydrogels with unique properties. These hydrogels can be dissolved, reformed, and retain their biochemical activity, making them suitable for various applications such as drug delivery and cell growth.
Researchers have developed an alginate hydrogel that can deliver angiogenic growth factors like VEGF and IGF to promote vascularization in ischemic tissues. The system increases blood flow and perfusion, improving muscle strength and tissue regeneration, with promising results in both young mice and aged rabbits.
Researchers at Johns Hopkins University have developed a new method to induce shape-changing in water-based gels using DNA molecules. By employing specific DNA sequences called 'hairpins,' they can cause a hydrogel sample to swell up to 100 times its original volume, and then halt the reaction with another DNA sequence.
Researchers at UBC Okanagan campus have created a new bio-ink made from cold-soluble gelatin, which shows promise for creating artificial organs. The hydrogel is thermally stable at room temperature, making it suitable for use in 3D bio-printing.
Scientists at University of Pittsburgh create vascularized pancreatic islet organoids using human pluripotent stem cells, offering potential treatment for Type I Diabetes. The innovative approach involves implanting blood vessel fragments into the islets before transplantation.
Scientists develop silver nanowire-coated textiles that provide multiple protection capabilities against extreme cold weather. These fabrics can capture sweat and maintain a consistent temperature, improving soldier comfort during missions.
Researchers developed a novel, tough, and triggerable hydrogel material that addresses safety concerns of traditional swallowable drug delivery systems. The new material can withstand gastrointestinal forces and release medication in a controlled manner.
Researchers at MIT have developed a gel-like material that can be coated onto standard plastic or rubber devices, providing a softer and more slippery exterior. The coating can also monitor and treat signs of infection, and could potentially replace common elastomers in medical devices.
A team of architects and chemists from the University of Cambridge has designed super-stretchy and strong fibres almost entirely composed of water. The new method improves upon earlier methods of making synthetic spider silk without high-energy procedures or extensive use of harmful solvents.
Researchers from HKUST created a B12-dependent light-sensing hydrogel by covalently stitching together photoreceptor proteins, enabling rapid gel-sol transition on light exposure. This allows for controlled release of stem cells and proteins with high spatiotemporal precision.
The study used FReI to investigate the folding stability and dynamics of proteins in hydrogels, revealing that hydrogels increase protein stability, speed up folding relaxation, and promote irreversible binding. The findings suggest that proteins may be destabilized when interacting with hydrogels.
A new hydrogel material combined with vascular endothelial growth factor (VEGF) has been shown to enhance the survival rate of transplanted insulin-producing cells in animal models. The technology could potentially treat more patients with type 1 diabetes and reduce the need for multiple donors.
Researchers at UC Riverside developed an inexpensive, biodegradable seaweed-based ant bait that reduced Argentine ant populations by 40-68% after four weeks. The hydrogel baits are highly absorbent and retain water to remain attractive to ants for extended periods.
Researchers develop a bacteria-fighting wound dressing made from the shells of crustaceans, which could prevent up to tens of thousands of infections annually. The dressing combines chitosan, an antibacterial and biodegradable substance extracted from crustacean shells, with hydrogel dressings to create a durable and elastic solution.
Hydrogels, jelly-like materials with water-based properties, require a better understanding of their structure and mechanical properties. Professor Ullal will use super-resolution microscopy techniques to characterize the structure of hydrogels and develop new materials.
A team of researchers at Duke University created a cartilage-mimicking material that can be 3D-printed to match the strength and elasticity of human cartilage, potentially easing damaged knees. The new material is custom-shaped to each patient's anatomy, providing improved shock absorption and reducing pain.