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Folding proteins feel the heat, and cold

Researchers refine theories on protein interactions with solutions, discovering new factors influencing folding, including thermal expansion and temperature. Atom-scale models reveal complex interactions between solvents and peptides, potentially changing our understanding of hydrophobic and hydrophilic effects.

SourceRice University·JournalThe Journal of Physical Chemistry Letters·DateNov 11, 2020

Pesticides can protect crops from hydrophobic pollutants

Researchers developed two approaches to control plant proteins related to hydrophobic pollutant transport. A pesticide that suppresses MLP gene expression reduced hydrophobic pollutant accumulation, while an MLP-binding pesticide inhibited binding to pollutants. This breakthrough enables safer crop production on contaminated soil.

SourceKobe University·JournalThe Science of The Total Environment·DateJul 27, 2020

Engineered botox is more potent and safer in mice

A new study engineered a form of botulinum toxin B with improved binding to nerve cells, increasing potency and reducing diffusion into surrounding tissue. The modified toxin demonstrated enhanced therapeutic potential and reduced adverse effects.

SourcePLOS·JournalPLOS Biology·DateMar 17, 2020

Physicists shed new light on how liquids behave with other materials

Physicists have made significant breakthroughs in understanding how liquids behave with other materials, including finding super-repellant substrates that can repel water. Their findings provide a comprehensive framework for tailoring material properties, which has important implications for various physical and biological systems.

SourceUniversity of Bristol·JournalProceedings of the National Academy of Sciences·DateOct 15, 2019

Charge change: How electric forces vary in colloids

The study highlights the importance of zeta potential in colloid surface chemistry and its effect on dispersion stability. The Navier boundary condition, considering relative velocity, is applied to particles with hydrophobic surfaces, leading to increased electrophoretic mobility and sedimentation potential.

SourceTokyo University of Science·JournalAdvances in Colloid and Interface Science·DateSep 12, 2019

Key evidence associating hydrophobicity with effective acid catalysis

A team of researchers from Tokyo Metropolitan University has demonstrated that the tunable hydrophobic nature of dense siloxane gels strongly correlates with their catalytic activity. The study shows that molecules with different hydrophobicity interact differently with surfaces, leading to increased or decreased catalytic activity.

SourceTokyo Metropolitan University·JournalJournal of the American Chemical Society·DateMar 23, 2019

Gip1 structure places G proteins in lockdown

Researchers at Osaka University have discovered the structure of Gip1, a protein that sequesters G proteins to block signaling processes. The unique molecular bonding arrangement allows interactions with G proteins, providing a better understanding of their mechanism.

SourceOsaka University·JournalNature Communications·DateNov 25, 2018

Antibacterial polymers

Researchers have synthesized a phosphonium polymer that exhibits extraordinary antibacterial activity despite lacking hydrophobic alkyl chains. The polymer's hydrophilic nature and balanced display of positive charges played a crucial role in its effectiveness.

SourceWiley·JournalAngewandte Chemie International Edition·DateSep 6, 2018

Future filters

Researchers at UCSB have identified a nuanced way to influence surface hydrophobicity, which affects how water interacts with solid surfaces. By varying the patterning of hydrophobic groups, they found that it can produce large effects on water dynamics, making it useful for designing more efficient membranes.

SourceUniversity of California - Santa Barbara·JournalProceedings of the National Academy of Sciences·DateAug 20, 2018

Tracking a solvation process step by step

Chemists at Ruhr-Universität Bochum tracked individual water molecules attaching to an organic molecule, exploring hydrophilicity and hydrophobicity. The study uses low-temperature scanning tunneling microscopy, providing insights into solvation processes.

SourceRuhr-University Bochum·JournalAngewandte Chemie International Edition·DateDec 21, 2017

Role of cooperativity in hydrophobic interactions revealed in real-time monitoring

Scientists have made a groundbreaking discovery using real-time monitoring to quantify cooperativity in hydrophobic interactions, demonstrating its critical role in stabilizing macromolecular assembly. The study's innovative microfluidic device enables precise tracking of solute molecule aggregation at sub-microsecond timescales.

SourceHong Kong University of Science and Technology·JournalNature Communications·DateJul 6, 2017

Nano-level lubricant tuning improves material for electronic devices and surface coatings

Researchers at University of Illinois developed a new approach to dynamically tune the micro- and nano-scale roughness of atomically thin MoS2, improving its hydrophobicity for various applications including waterproof electronics and medical devices. The study expands toolkit for tunable wettability of 2D materials.

University of Illinois researchers demonstrate tunable wetting and adhesion of graphene

University of Illinois researchers have demonstrated doping-induced tunable wetting and adhesion of graphene, revealing its unique properties. The findings show that graphene can exhibit switchable hydrophobic and hydrophilic behavior, enabling the creation of reusable, self-cleaning sensors with potential energy savings.

Gels go drugs

Physicists at Lomonosov Moscow State University propose a theoretical model for analyzing the conformational behavior of hydrophobically modified polymer gels in solution. The model explains experimentally observed phenomena and reveals new ways to control gel susceptibility, promising applications in drug delivery systems.

SourceLomonosov Moscow State University·JournalThe Journal of Chemical Physics·DateMay 30, 2016

Engineers create a better way to boil water -- with industrial, electronics applications

Researchers at Oregon State University have created a new technology to induce and control boiling bubble formation. This innovation has the potential to improve the efficiency of steam boilers in large electric generating facilities. The approach uses piezoelectric inkjet printing and zinc oxide nanostructures to precisely control bub...

SourceOregon State University·JournalScientific Reports·DateMay 4, 2016

New surfaces delay ice formation

Researchers create biphilic surface that repels water in some areas and attracts it in others, delaying frost formation even at 6 degrees below freezing. The unique condensation dynamics on the surface cause small droplets to merge and release energy, delaying freezing for over 3 hours.

SourceAmerican Institute of Physics·JournalApplied Physics Letters·DateOct 6, 2015

Dancing droplets launch themselves from thin fibers

The 'dancing droplets' phenomenon allows small droplets to launch themselves from moderately hydrophobic surfaces, enabling efficient removal of accumulated droplets in fibrous webs. This technology has potential applications in water purification and oil refining by reducing clogging and improving efficiency.

SourceDuke University·JournalPhysical Review Letters·DateAug 17, 2015

Recipe book for colloids

Researchers from Forschungszentrum Jülich create a comprehensive phase diagram that describes the material properties of colloids based on their structure and concentration. The study finds that the interaction length, which determines the solubility of the colloid solution, can be tuned to achieve specific macroscopic properties.

SourceForschungszentrum Juelich·JournalNanoscale·DateAug 14, 2015

How lipids are flipped

Researchers from ETH Zurich have determined the structure of a flippase, PglK, that flips lipid-linked oligosaccharides, revealing a novel mechanism. The discovery sheds light on fundamental biological processes and may lead to therapeutic approaches for diseases associated with glycosylation disorders.

SourceETH Zurich·JournalNature·DateAug 12, 2015

Like water for batteries

A University of Pittsburgh study reveals that graphite materials are actually hydrophilic due to airborne contaminants. This discovery has significant implications for lithium-ion batteries and super capacitors, which may lead to stronger and more durable devices.

SourceUniversity of Pittsburgh·JournalNature Materials·DateJul 29, 2013

Illinois chemical/bioengineers use adhesion to combine advantages of silicones and organic materials

University of Illinois bioengineers find way to permanently modify silicone polymer surface with organic material, resulting in stable adhesion for several months. The method enables practical applications in cell culture platforms, microfluidic devices, and tissue engineering.