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Illuminating the no-man's land of waters' surface

Researchers challenge a long-held hypothesis on water's surface charge, finding that intrinsic properties of water molecules are responsible. Using advanced techniques like nonlinear optics and light diffusion, scientists detect negative charges even in the absence of impurities.

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How do protein binding sites stay dry in water?

Researchers studied model cavity and tunnel structures resembling protein binding sites to understand their ability to stay dry. Geometric shields prevent water molecules from penetrating at the nanoscale.

In the pursuit of dangerous clumps

Researchers at Helmholtz-Zentrum Dresden-Rossendorf develop a system to recreate amyloid formation on artificial surfaces, providing insights into disease mechanisms. The customized mica surface exhibits hydrophobic properties, facilitating the formation of oligomers and fibrils that can destroy cell surfaces.

New lab-on-chip advance uses low-cost, disposable paper strips

Researchers at Purdue University have developed a technique to create microfluidic devices on paper strips, enabling more complex chemical assays and applications in medicine and research. The approach uses a laser to modify paper with patterns, allowing for the detection of specific chemicals and biological molecules.

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Triblock spheres provide a simple path to complex structures

University of Illinois researchers developed a simple method to create intricate lattice structures using triblock Janus spheres. The innovative material exhibits self-assembly capabilities, enabling the creation of porous sheets with tailored properties for specialized filtering applications.

Nanoparticle gives antimicrobial ability to fight Listeria longer

A Purdue University research team developed a nanoparticle that can hold and release an antimicrobial agent, preserving its effectiveness against Listeria monocytogenes for up to three weeks. The nanoparticle attracts and stabilizes nisin, a food-based antimicrobial peptide, allowing for extended use in foods susceptible to Listeria.

Mimicking nature, scientists can now extend redox potentials

Researchers at the University of Illinois have discovered a way to fine-tune the reduction potential of copper-containing proteins, enabling the creation of efficient water-soluble redox agents. This breakthrough allows for greater control over electron-transfer properties and extends the range of redox potentials.

Boron-based compounds trick a biomedical protein

Researchers at the University of Oregon have successfully demonstrated that specially synthesized boron compounds can be accepted by biologically active enzymes. This breakthrough could lead to new drug design strategies and boost boron's expanding use in medicine.

MIT: Extending the shelf life of antibody drugs

A new computer model developed at MIT allows researchers to design more stable antibodies, reducing clumping and aggregation issues. The model identifies regions responsible for aggregation and enables mutation of amino acids to increase stability without affecting function.

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Research gives clues for self-cleaning materials, water-striding robots

Scientists at the University of Nebraska-Lincoln and RIKEN institute developed a computer simulation to design nanostructured surfaces with superhydrophobic properties. This technology can help create self-cleaning materials and water-striding robots, which are inspired by nature's ability to repel water.

Bristly spheres as capsules

Scientists have produced amphiphilic hybrid particles consisting of water-insoluble inorganic nanoparticles at the core surrounded by bristle-like layers of hydrophilic polymer chains. The nature of these aggregates depends on the density of polymer

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Cellular construction methods emulated

The Dutch team used two types of self-aggregating compounds: surfactants and gelators. They formed aggregates that coexisted without interfering with each other, resulting in complex structures with separate compartments. This orthogonal self-aggregation enables the creation of versatile compartmentalized systems.

UT-ORNL governor's chair unlocks secrets of protein folding

Researchers reveal driving force behind protein folding involving water interactions and hydrophobic areas of peptides. This insight builds on previous theories, allowing for the determination of a peptide's structure from its amino acid sequence.

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Emulsion with a round-trip ticket

Researchers successfully create a double inversion of an emulsion by adding surfactant to a nanoparticle-containing mixture. The process, which uses silica nanoparticles and a specific type of surfactant, allows for the conversion between oil-in-water and water-in-oil emulsions.

Water theory is watertight, researchers say

A team of researchers from the University of Illinois and Argonne National Laboratory has confirmed a long-standing theoretical prediction about water's behavior on hydrophobic surfaces. They found a thin layer of depleted water at the interface, contradicting previous findings of nanobubbles.

Bio-inspired assembly of nanoparticle building blocks

Researchers at Rice University have discovered a novel method for assembling gold and silver nanoparticle building blocks into larger structures, inspired by the self-assembly of lipid membranes that surround every living cell. The new technique allows for the creation of ultra-potent cancer drugs and efficient catalysts.

Mind the gap

A team of scientists used high-energy X-rays to study the hydrophobic water gap, revealing its size and characteristics. The study provides new insights into protein folding and stability, which are crucial in biological systems.

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CU, Scripps researchers provide evidence of how proteins fold

A study by CU, Scripps researchers provides evidence of how proteins fold to create their characteristic shapes and biological functions. They propose that nonpolar groups in a polypeptide chain are responsible for initial folding, which then propagates to form the final folded structure.

Sandia researchers solve mystery of attractive surfaces

Sandia researchers found that rough hydrophobic surfaces exhibit longer-range attractive forces, which may help explain protein folding and the self-cleaning 'Lotus effect'. By inserting rough surfaces into experiments, they slowed down the reaction to measure the attraction and observe its origin, a cavitation bridge between the subme...

UCSD chemists develop self-assembling silicon particles

Researchers at UCSD create tiny silicon chips, 'smart dust,' that can detect chemical or biological compounds and report information to the outside world. The dual-sided particles can collect at a target and self-assemble into a larger reflector for remote sensing applications.

Non-toxic anti-fouling coating for ships

Researchers at Cornell University have developed a non-toxic paint that effectively prevents marine fouling by creating a self-cleaning surface. The hydrophilic and hydrophobic materials, tested by the ONR and other collaborators, deny bacteria a compatible surface to grow on, reducing fouling.

Reversible switch presages new paradigm for surface design

The UCSB team has developed a reversible switch for surface design, allowing for dynamic regulation of macroscopic properties. The technology uses alkanethiolates to create nanometer-thin interfaces that can be controlled as a function of space and time.

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