Articles tagged with Biomaterials
Researchers developed a multi-functional biomaterial that eradicates residual cancer cells, prevents bacterial colonization, and regenerates missing bone tissue. Gallium oxide selectively targets bone cancer cells overexpressing transferrin receptors, causing cell death, while preventing infection in surgical sites.
Scientists discovered a protein secreted by deep-sea extremophile Pyrodictium abyssi that self-assembles into a highly stable biofilm. This discovery opens new avenues for biomedical research and could lead to breakthroughs in wound dressing, medical device coatings, and tissue engineering.
New research reveals that asthma attacks cause overproduction of extracellular proteins and growth of blood vessels in the airways. Over time, these changes lead to constriction of breathing passages, resulting in long-term respiratory issues.
Researchers found that CAR3 coordinates bone formation and regeneration by forming a molecular complex with collagen type I alpha 1 and recruiting bone sialoprotein. The study identified CAR3 as a previously unrecognized regulator of osteoblast differentiation, highlighting its potential for treating bone disorders.
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
Researchers developed a bidirectional interface that uses muscle vibrations to restore natural sensations of movement in upper limb prosthetics. The system restored coordinated hand grasp movement patterns, or 'synergies,' similar to those felt by participants with different kinesthetic feedback systems.
New instruments promise precise measurement and manipulation of tiny nanomaterials used in manufacturing, aerospace and medicine. Researchers can now study the smallest heavy metals with water filters, developing more resilient structures.
Researchers Edward Lemke and Andreas Walther from Johannes Gutenberg University Mainz have been awarded ERC Advanced Grants for their innovative projects, Molecular Shape Microscopy and Protoecologies between Artificial Cells and Mammalian Cells. The grants aim to advance our understanding of protein function in living cells and explor...
Researchers at Shinshu University discovered a unique surface architecture in the petals of the hardy ice plant that produces glossy appearance. The parabolic ridge structures reflect and concentrate light, creating gloss across a broad range of viewing angles.
Researchers developed a topical gel formulation with 4-aminopyridine to treat burn wounds, achieving near-complete closure in 21 days. The gel delivers the drug directly to the wound site, avoiding systemic risks associated with prolonged use.
Researchers at Chalmers University of Technology developed a new bio-based material using yeast, cellulose, alginate, glycerol, and water. The material can be 3D printed, has customizable properties, and is biodegradable, offering an environmentally friendly alternative to traditional building materials.
Researchers developed a nanofiber drug delivery system that uses electrospun fiber membranes to deliver multiple drugs in concert, demonstrating improved efficacy against glioblastoma. The system enables localized long-term delivery of drugs directly at the tumor site after surgery.
Researchers at Institute of Science Tokyo genetically engineer cyanobacteria to produce sulfated polysaccharides, a sustainable route for manufacturing biomaterials. The study demonstrates the feasibility of engineering complex biosynthetic pathways in photosynthetic organisms.
Researchers summarize how AI is accelerating inorganic biomaterial development for various biomedical applications. AI-powered property prediction and inverse design tools are being used to discover effective materials with unique properties.
The NTU Singapore team developed a tiny seed-sized robot that can perform five surgical functions wirelessly, including cutting and releasing drugs. The robot is controlled by weak magnetic fields and takes under a second to switch between functions. It has the potential to make surgeries more precise and safer.
Researchers at the University of Bath discovered that a fungus can break down hard-to-recycle construction waste and turn it into sustainable insulation. The resulting biomaterial has comparable thermal performance to conventional insulation products with significantly lower carbon emissions.
The collaboration solves a main challenge in ocular wearables by integrating ultra-thin, durable, and stable energy storage. XPANCEO develops smart contact lenses with AR and health monitoring capabilities, while ITEN provides high-power-density solid-state batteries.
Researchers at the Smithsonian National Museum of Natural History analyzed 18 scorpion species and found striking patterns in metal concentration and distribution among their pincers and stingers. The study reveals that zinc plays a role beyond hardness, possibly enhancing durability, and provides insight into how organisms adapt to pr...
Researchers at Tohoku University developed a strong, biodegradable material made from bamboo sheets and PHBH, which can be used to estimate biodegradation in seawater. The material's strength is linked to its degradation rate, providing a predictable usable lifetime for sustainable materials.
Oregon Health & Science University has received significant NIH funding to develop advanced microphysiologic models that mimic how cancers grow and respond to treatment within bone tissues. Two new awards focus on osteosarcoma and prostate cancer, aiming to improve understanding of disease spread and treatment responses.
Researchers found that extracellular vesicles from menstrual blood stromal cells can improve cartilage function and slow tissue degradation, even in older postmenopausal women. Biomimetic scaffolds are being developed to prolong the effects of these particles, offering a potential cell-free therapy for osteoarthritis.
A new clinical trial at the University of Cincinnati is testing a peptide solution to treat prosthetic joint infections after total knee replacement. The trial aims to reduce the need for repeat surgeries and expand the treatment window beyond two weeks.
A team of researchers has achieved a major milestone in developing a new treatment aimed at helping the body repair damaged joints at the source. The experimental treatments have shown promising results in animal models, restoring joint tissue to near-normal levels and significantly reducing pain markers for long periods.
A team of researchers at North Carolina State University has created an injectable microgel called B-knob triggered microgels (BK-TriGs) that can help reduce bleeding in infants during surgery. The microgel works by mimicking the mechanical properties of natural platelets, which helps to create fibrin networks and stanch bleeding.
New research demonstrates that restoring the physical stiffness of the gingival tissue can fundamentally change how cells respond to infection, potentially paving the way for new treatments. The study uses a hydrogel system to investigate how gum tissue stiffness impacts periodontal disease inflammation.
Researchers identify a three-way link between mechanical stress, integrin signaling, and endocytosis in osteoarthritis. Integrin trafficking may help explain why the same pathways have different effects across disease stages and tissue contexts.
The Terasaki Institute for Biomedical Innovation and UCLA Technology Development Group will co-curate an Advanced Organ and Tissue Repair (AToR) session at LABEST, featuring leading experts in regenerative medicine. The session aims to accelerate the translation of breakthrough technologies into real-world clinical solutions.
Researchers create living tissue at near-physiological cell density using a new bioprinting strategy called embedded 3D printing in a cell-dense suspension (EPICS). The method enables the precise fabrication of perfusable channels and dense cellular environments, mimicking real organs.
Researchers at Penn State have developed a new class of tunable biomaterials, known as granular aerogel scaffolds, to support tissue regeneration and vascularization in wound healing. The material offers improved cell infiltration and may help rapidly form new blood vessels and regenerate damaged tissue.
Researchers developed a spray shield that adheres to transplant organs using mussel-derived adhesive protein, reducing immune rejection and its side effects. This innovation enables targeted delivery of immunosuppressants directly to the transplanted site, increasing success rates in xenograft transplantation.
A research team from Xi'an Jiaotong University has developed a method to align cells in muscle tissue using electric forces during electrohydrodynamic bioprinting. This breakthrough allows for the creation of living muscle tissues with tightly aligned cells, enabling the production of functional muscle constructs.
Researchers introduce Fe₃O₄@mPEG-Ag nanoparticles as a non-antibiotic strategy to combat drug-resistant bacteria. The novel nanomaterial demonstrates strong antibacterial activity against clinically relevant multidrug-resistant strains.
Researchers at UNLV have created a 3D-printed synthetic California sea lion pelvic region, enabling medical professionals to conduct blood collection training on anatomically authentic models. This innovation has the potential to improve veterinary procedures and benefit human lives in the long run.
Researchers from the University of Ottawa have developed a groundbreaking biomaterial that combines strength, adaptability, and biological compatibility for soft tissue repair. The hydrogel is made from synthetic peptides and can be precisely tailored through chemical design, making it an attractive alternative to existing biomaterials.
Researchers at Tokyo Metropolitan University have created a neutral molecule that can carry DNA into biological cells using a process called annealing. This breakthrough promises more effective therapies by reducing inflammation and improving delivery efficiency.
Researchers at Harvard's John A. Paulson School of Engineering and Applied Sciences have developed a new fabrication method for printing robotic devices with long filaments featuring precisely placed hollow channels. This allows the device to bend and deform in predetermined ways, enabling the creation of soft robots with predictable s...
Researchers at RCSI have developed an RNA-activated implant that delivers growth-promoting particles to injured nerve cells, encouraging them to regrow after spinal cord injury. The implant helps overcome molecular barriers by silencing a gene called PTEN.
Researchers have developed a biointegrated material that resists hydration and increases in strength to values above commodity plastics when wet. The process does not alter the biological nature of chitosan, enabling seamless reintegration into natural ecological cycles.
Researchers developed an oxygen-delivering gel to heal chronic wounds that fail to heal for more than a month. The gel conforms to the wound's shape and provides continuous oxygen levels, helping transform nonhealing wounds into normal injuries.
A study by University of Texas at Dallas bioengineers found that both cancerous and noncancerous colon tissue from young patients with colorectal cancer was mechanically stiffer than in older patients. This stiffness may promote the development of early-onset colorectal cancer, a condition rising over the past 30 years.
Researchers discovered functional gradients in elephant and cat whiskers, allowing for precise touch sensing. The stiff-to-soft transition enables elephants to navigate their environment with ease, including picking up delicate objects.
Researchers at TUM developed a coating that makes UV-A radiation visible using proteins and bacteria, opening up new possibilities for sustainable materials. The coating, which includes the protein mEosFP, reliably detects contact with UV-A light and can be integrated into paints and coatings without compromising material properties.
The Rice lab will produce bioprinted, vascularized kidney tissue that augments renal function in patients with kidney disease. The implantable kidney tissue will be made from a patient's own cells combined with a bioink that supports the long-term viability of the implanted cells.
Researchers developed smart 4D-printed vascular stents that expand naturally at body temperature, eliminating the need for external heating. The stents balance mechanical flexibility and radial strength, demonstrating long-term biomechanical compliance.
Researchers at Flinders University developed a high-performance coating made from peppermint essential oil that protects against infection, inflammation, and oxidative stress. The coating demonstrates strong antibacterial action against key pathogens, including E. coli and Pseudomonas aeruginosa.
A new hydrogel gel, inspired by nature's NETs, uses near-infrared light to kill bacteria and calm the immune system, promoting wound healing. Trials in mice and pigs show significant reduction in bacterial load and accelerated healing.
Researchers created eco-friendly, high-performance gas sensors with blended polymer films combining poly(3-hexylthiophene) and poly(butylene succinate). The sensors demonstrated stable performance and higher sensitivity to nitrogen dioxide and other gases.
LIST's patented infrared welding process enables rapid assembly of thick carbon-fibre-reinforced thermoplastic components, reducing weight, costs and environmental impact. The innovation is estimated to reduce CO2 emissions by 12.5 tonnes per wing rib.
Agricultural waste from crops like wheat, rice, and maize can act as a powerful carbon sink when diverted into construction products. The study finds that these materials can store carbon for decades rather than releasing it within months.
Researchers found that Ralstonia's unique exo polysaccharide 1 (EPS-1) film allows the bacteria to spread rapidly through plant xylem vessels, causing rapid wilting. The team used precise measurements of the viscoelastic properties of EPS-1 to understand its role in making Ralstonia a devastating plant killer.
A team of researchers has created an object identification system for prosthetic hands to guide appropriate grip strength decisions in real time. The system uses a camera and EMG sensor to determine the user's intent and predict the required grip strength, enabling users to focus on daily tasks without complex training or calibration.
The new manual provides comprehensive guidance on designing permanent bamboo structures, covering topics such as fire safety and durability. It aims to support the global use of bamboo construction, a low-carbon alternative with remarkable mechanical properties.
Researchers have developed a breakthrough light-responsive Janus dural patch using photocurable hyaluronic acid, providing strong wet adhesion and preventing unwanted tissue adhesion. The patch seals wounds within five seconds with minimal swelling and high biocompatibility.