Articles tagged with Biomaterials
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Bioengineers at Harvard John A. Paulson School of Engineering and Applied Sciences have developed a computational model called BrainFlow that simulates cerebrospinal fluid flow in the presence of shunt implants, providing insight into optimal shunt design and placement for hydrocephalus patients.
GeniPhys has received FDA clearance for its self-assembling collagen scaffold, Collymer Self-Assembling Scaffold (SAS), which supports cellular infiltration and vascularization. The technology is indicated for various wound types and anchors a growing intellectual property portfolio with nearly 20 issued or pending patents.
Tina Rost will use a $800,000 NSF CAREER award to control the disorder in high-entropy ceramics, making them stronger and more heat-resistant. Her team aims to develop new materials with tailored electrical, magnetic, and mechanical properties using machine learning-enhanced analysis.
The study highlights the challenges of commercializing renewable polymers, but also emphasizes the potential of chemical modification to improve their properties for clinical use. The research aims to provide a comprehensive overview of these sustainable materials in biomedical practice.
Researchers develop biodegradable material that cools temperatures by up to 9.2°C and reflects 99% of sun's rays, reducing energy consumption by 20% a year in hot cities.
Researchers developed biomaterial patches loaded with basic fibroblast growth factor to enhance esophageal anastomosis healing. The study showed improved mechanical strength, increased fibroblast proliferation, and enhanced collagen secretion in the experimental group compared to controls.
Researchers developed a novel amine-functionalized graphene oxide (NGO) membrane reactor for ultrafast synthesis of propranolol, achieving nearly 100% conversion and selectivity in under 4.63 seconds at 23°C. The NGO membrane exhibited higher catalytic flux and turnover frequency compared to the acidic graphene oxide (GO) membrane.
Bioengineering researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a soft, thin, stretchable bioelectronic device that can be implanted into a tadpole embryo's neural plate, recording electrical activity from single brain cells with millisecond precision.
Scientists at Penn State created mats from tiny fibers made from milk protein and cellulose, showing promise for sustainable food packaging, wound dressings, cosmetics, filtration and more. The fiber mats can be transformed into clear films that hold potential for food wrap.
Scientists replace toxic additives in hydrogels with D-sorbitol, a safe sugar alternative found in chewing gum, to create bioelectronic devices that are soft, safe, and integrated with natural tissue. The new material has increased biocompatibility and improved electronic performance.
The University of Houston has launched a $3M Cancer Immunotherapy Biomarker Core to accelerate early diagnosis and treatment response in cancer. The core will offer comprehensive targeted proteomic cancer biomarker screens, enabling researchers to identify better biomarkers for cancer.
Researchers at TU Wien have developed a method to create artificial blood vessels using ultrashort laser pulses, enabling the creation of mini organ models with precise control and reproducibility. The technology has been successfully applied to liver tissue models, resulting in improved metabolic activity and adequate nutrient supply.
The Stuttgart Cluster of Excellence IntCDC will continue to develop innovative construction methods that reduce resource consumption and CO2 emissions through computational design and engineering methods. The cluster aims to evolve its Co-Design approach into a Co-Agency approach, focusing on bio-based building materials, AI technologi...
Materials researchers at Harvard have created a way to produce natural rubber that retains its stretchiness and durability while improving its ability to resist cracking. The new material is four times better at resisting slow crack growth during repeated stretching and 10 times tougher overall.
Antonios Mikos, a leading expert in biomaterials and tissue engineering, has been elected to the European Academy of Sciences. He is recognized for his groundbreaking work in regenerative medicine, controlled drug delivery, gene therapy, and disease modeling.
Researchers found that microscopic structural changes in heart cells naturally narrow with age, stabilizing heart rhythm and reducing the risk of irregular heartbeats. This discovery challenges the idea that all age-related changes in the heart are harmful.
Researchers at Virginia Tech have designed a new metallic material alloy with superior mechanical properties, leveraging data-driven frameworks and explainable AI. This breakthrough accelerates the discovery of advanced metallic alloys, offering insights into materials' structure-property relationships.
Scientists have developed a sugar-coated nanotherapy that effectively traps misfolded proteins, neutralizing their toxic effects on neurons. The treatment significantly boosts the survival of lab-grown human neurons under stress from disease-causing proteins.
A synthetic lichen system developed by Texas A&M researchers enables concrete to heal itself without outside intervention. This innovation uses cyanobacteria and filamentous fungi to produce crack-filling minerals, setting it apart from previous self-healing concrete endeavors.
Researchers create silk iron microparticles that can be guided using a magnet to deliver drugs and treatments precisely to sites in the body. The development has potential applications in regenerative medicine, cancer therapies, and cardiovascular disease treatment.
Researchers developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure. The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack, showing effectiveness up to five weeks after injection.
Researchers at Carnegie Mellon University have developed a novel FRESH bioprinting technique that enables the creation of microphysiologic systems entirely out of collagen, cells, and other proteins. This advancement expands the capabilities of studying disease and building tissues for therapy, such as Type 1 diabetes.
Dr. Ali Khademhosseini, TIBI Director, receives the 2025 MRS Mid-Career Researcher Award for his groundbreaking contributions to biomaterials science and tissue engineering. His research has revolutionized engineered tissue constructs for drug discovery and regeneration.
Researchers highlight biodegradable plastics as a promising solution to single-use plastic waste, with the packaging segment accounting for half of single-use plastic production. The market is expected to reach $105 billion by 2024, driven by consumer awareness and corporate response.
Researchers have developed a building material that uses fungal mycelium and bacteria cells, which can self-repair for at least a month. This innovation has the potential to replace conventional building materials with high carbon footprints like cement, reducing emissions and promoting sustainability.
Researchers utilized machine learning models to identify key surface attributes modulating immune response, paving the way for improved implant materials. The study revealed pivotal factors regulating cytokine secretion and offered insights into designing alloys with optimized immunoregulatory functions.
Jennifer L. West, UVA Engineering Dean and Saunders Family Professor of Engineering, has been awarded the 2025 Pierre Galletti Award for her innovative research in biomaterials and nanomedicine. Her work has led to breakthroughs in treating cancer with precision, offering new hope to patients battling hard-to-treat cancers.
A team of scientists discovered a method to produce a stable and conductive bioelectric material without the need for a chemical crosslinker. The new process uses high heat to stabilize the material, producing devices with three times higher electrical conductivity and more consistent stability.
Researchers identified a Y chromosome-linked gene, UTY, as a key driver of valve calcification in males. In females, fibrotic tissue formation stiffens the valve, leading to different disease progression. The study highlights the importance of sex-based mechanisms in heart valve disease
Researchers developed magnetic micro swimmers covered in a thin coating of magnetic nanoparticles, unaffected by the coating. The algae maintained their swimming speed after magnetization and navigated 3D-printed channels using magnetic guidance.
Researchers have made significant progress in applying tissue engineering to spinal cord injury (SCI) repair. Biomaterials such as hydrogels and decellularized extracellular matrix promote nerve regeneration, while stem cells and exosomes enhance functional recovery.
Researchers at Institute of Science Tokyo designed a protein cage system that can control and visualize orientational changes in aromatic side chains through strategic binding of fluorescent ligands. This approach enables precise control over protein dynamics while enhancing fluorescence properties, with potential applications in biomo...
The article reviews additive manufacturing technology for biomedical metals, enabling customized implants with precise internal structures. It highlights the integration of AI and 4D printing, addressing challenges in production costs, regulatory compliance, and post-processing.
Researchers at the University of Sydney are using Zwitterions to create materials that can prevent blood clots from forming in medical devices and implants. They have successfully created a zwitterionic coating that repels water beyond the material's boundaries.
Researchers developed mini biohybrid rays using cardiomyocytes and rubber, demonstrating improved swimming efficiencies approximately two times greater than previous biomimetic designs. The application of machine-learning directed optimization enabled an efficient search for high-performance design configurations.
A Virginia Tech research team has made significant progress in understanding the role of physical properties in tuning the body's immune responses. By modifying biomaterials' size, shape, and stiffness, they aim to enhance immune cell behavior and stimulate antitumor immune responses.
A new biodegradable polymer-based delivery system efficiently transports mRNA, outperforming existing lipid nanoparticles in delivery efficiency and expression duration. The study also shows improved immune response results without liver accumulation or toxicity.
Three UVA engineering professors, James T. Burns, Coleen Carrigan, and Liheng Cai, have received the Presidential Early Career Award for Scientists and Engineers (PECASE) from President Biden. The award recognizes their innovative work in science and technology, including Burns' research on material fracture under unique conditions and...
Lehigh University bioengineering researcher Tomas Gonzalez-Fernandez is exploring how combining CRISPR with biomaterials can improve gene editing's safety and efficacy for therapeutic use. His NSF CAREER award-funded research aims to develop more targeted and controlled therapies for genetic diseases.
A new study by civil engineers and earth systems scientists at the University of California, Davis and Stanford University suggests that storing carbon in buildings could help reduce greenhouse gas emissions. The researchers calculated that using carbonated aggregates to make concrete could absorb a gigaton of CO2 annually.
Researchers developed a novel inhalable therapeutic delivery system for lung cancer using mucoadhesive protein nanoparticles inspired by marine mussels. The approach leverages the adhesive properties of mussel proteins to enable selective payload release and minimize adverse effects.
A new bone regeneration scaffold, Qx-D, shows promise in treating infected bone defects by exhibiting broad-spectrum antibacterial activity against various bacteria. The scaffold also supports the adhesion and differentiation of key cell types involved in bone regeneration.
A QUT-led study found that surgeons are slow to adopt newly developed biomaterials or tissue-engineered solutions for treating bone defects. The researchers surveyed 337 surgeons and 99 scientists, revealing a significant gap between their optimism about future advancements and the slow adoption of these innovations in clinical practice.
Researchers developed nanocomposites that effectively reduce noise and improve signal transmission for brain pacemakers. The materials use a combination of graphene and clay to absorb and disperse energy, reducing the impact of external electrical fields on patients.
The InteReg project aims to create interactive biomaterials that instruct cells to regenerate after brain or spinal cord injuries, potentially treating MS and other neurological disorders. The project, funded by the Carl Zeiss Foundation, brings together experts in biology, chemistry, medicine, and polymer research.
Advanced research identifies potential molecular instructions determining echinoderms' ability to adapt and regenerate tissues. The breakthrough could lead to new regenerative therapies and smart collagen-based biomaterials for treating human health conditions.
Researchers at Harvard University have developed a tissue-anchoring mechanism for medical devices, inspired by the circular hook-like attachment organ found in intestinal tapeworms. The device can be deployed in under 1 millisecond and anchors into soft tissue with minimal damage.
Researchers at Kyushu University develop a novel technique for building complex 3D microfluidic networks using plant roots and fungal hyphae in silica nanoparticles. This bio-inspired method enables the creation of intricate biological structures, opening new opportunities for research in plant and fungal biology.
Team Bath Heart, a team of students from the University of Bath, has won the second world Heart Hackathon title with their innovative artificial heart device. The team's prototype, which uses wireless charging and 3D printing, was praised for its novelty, progress, and presentation.
Researchers develop novel Ta-based implants with improved biocompatibility and osseointegration properties, enabling better bone growth and stability. The designs optimize mechanical and biological requirements for optimal clinical results.
Researchers developed porous dermal fillers that accelerate tissue healing and regeneration for diabetic wounds. The novel approach combining electrospinning and electrospraying technologies creates biocompatible microspheres that promote cell migration, granulation tissue formation, and neovascularization.
A Carnegie Mellon University-led team is developing a bioelectronic implant called ROGUE that can produce a year's supply of treatment for chronic diseases like Type 2 diabetes and obesity. The device will offer continuous, adjustable therapy deployment via a minimally invasive procedure.
Researchers found significant challenges in spider silk production, including scale-up issues and toxicity concerns. The study highlights potential host organisms for producing spider silk, such as microbes and bacteria, to address these challenges.
Researchers developed a novel approach to optimizing siRNA-loaded lipid nanoparticles using NMR-based molecular-level characterization. Pre-mixed LNPs exhibit superior gene-silencing effects due to a stacked bilayer structure that enhances gene silencing.
Researchers are working on a new method for preserving microbial samples using microfluidics, biomaterials, and protein engineering. The goal is to improve biosurveillance and protect soldiers and civilians from infectious diseases.
A team from the University of Michigan School of Dentistry has patented a new regenerative bone graft material that can regenerate about eight times more bone than existing scaffolds. The breakthrough could transform bone grafts for millions of people who require them, reducing costs and complications associated with traditional methods.
Researchers at Kyushu University developed a new organic thermoelectric device that can generate power from ambient temperature. The device, composed of copper phthalocyanine and fullerenes, achieved an open-circuit voltage of 384 mV and a short-circuit current density of 1.1 μA/cm².
The researchers synthesized supramolecular polymers with the ability to form larger complexes in response to external stimuli, which may shed light on biomolecular self-assembly and other ‘smart’ materials. The resulting shape of the assemblies can be controlled based on the concentration of a specific additive.
The Journal of Bioresources and Bioproducts is a leading open access journal fostering transformative research on bioresource conversion into biomaterials, biochemicals, and bioenergy. The journal's eight thematic areas focus on cutting-edge topics in sustainable energy and materials science.
Researchers at PolyU have invented a unique fluidic processor called Connected Polyhedral Frames (CPFs), which enables reversible switching between liquid capture and release. CPFs offer a versatile platform for various applications, including controlled multidrug release, biomaterial encapsulation, and air conditioning.