Articles tagged with Biomaterials
A coral-inspired 3D-printed scaffold reprograms immune cells to promote angiogenesis and bone regeneration, shifting macrophages from inflammatory M1 state to reparative M2 state. The scaffold also enhances angiogenesis, new bone formation, and reconstruction of bone defects.
Researchers have developed a new hydrogel made from peptides that can transport ions, generate electrical signals when squeezed, or interact with cells and biological molecules. The gel has tiny water channels and is electrically polarized due to its highly organized structure made from nanofibers.
A team in Japan has created a propellor-shaped lipid mimic molecule that forms stable 'islands' in a 'sea' of lipid, achieving phase separation and high thermal stability. This new design principle can be used to engineer domains in artificial membrane materials for various applications.
Kyushu University researchers create a self-healing hydrogel packaging that tracks food spoilage through color changes, extending shelf life by 12 hours. The material can also repair itself, making it more durable and reliable in practical use.
Scientists at North Carolina State University have created a highly-porous, superadhesive mesh that can capture both large and small microplastic particles, including those as small as tens of nanometers. The mesh is made from sustainable biopolymers and can clean microplastics from both saltwater and freshwater.
Researchers explore how engineered lanthanide carriers can tune the optical and magnetic properties of ions for improved signal contrast and reduced background signals in biomedical imaging. The study highlights opportunities for multimodal imaging, theranostics, and AI-guided probe design.
A University of Virginia researcher received a $2.1 million grant to develop advanced laboratory tissue models that could improve drug testing, deepen scientists' understanding of disease, and reduce the need for animal testing.
Recent progress in lanthanide carriers is mapped to improve biomedical imaging and diagnosis, combining optical, X-ray, and magnetic resonance imaging techniques. These carriers enable high-resolution imaging with tunability for different applications, reducing tissue damage and enhancing image clarity.
Researchers have developed a way to quickly create customizable synthetic blood vessel grafts in just minutes using additive manufacturing. The new technique, called Focused Rotary Jet Spinning, allows for precise control over diameter and wall thickness, making it ideal for acute trauma situations and complex pediatric heart surgeries.
Scientists at the University of Osaka have created a new technique to build blood supply systems for artificial tissues. They successfully fabricated tubular hydrogel structures with controlled lumen sizes and complex geometries, paving the way for creating vascular models that can investigate the development of fully synthetic tissues.
A new study reveals that lignin can be transformed into a bioactive material that promotes the formation of bone-like minerals while supporting the growth of bone-forming cells. The material also degrades gradually under physiological conditions, making it suitable for scaffolds intended to be replaced by newly formed bone during healing.
Researchers have designed a tough, fatigue-resistant, and multifunctional biogel for next-gen wearable electronics. The biogel enables self-powered devices for gesture recognition and robotic hand control with high precision.
JMIR Publications is sponsoring the upcoming BioMedEng26 conference to promote biomedical engineering innovation. The journal JMIR Biomedical Engineering will be highlighted during the event, with Dr. Javad Sarvestan discussing its focus on cutting-edge engineering applications and peer-review process.
Scientists at Murdoch University mapped the genes of Salinivibrio bacteria from Rottnest Island's salt lakes, revealing their potential for producing biodegradable plastic. The study found seven new genes that may enable some strains to break down the plastic.
Researchers at Hiroshima University have developed a new way to detect subtle, early-stage changes in human skin collagen using advanced optical imaging and chiroptical spectroscopy. The study reveals that the molecular organization and supramolecular chirality of dermal collagen collapses prior to visible fiber thinning or fragmentation.
Researchers developed nanoparticles that retain their protective coating in normal tissue but shed it upon reaching tumor tissue, releasing anticancer drugs. This technology reduces systemic side effects and enhances treatment efficacy.
A novel, two-sided dressing made from sustainable polymers has been developed to deliver antibiotics directly to wounds during critical early stages of infection. The dressing reduces bacterial growth and biofilm formation by over 90%, promoting healing and reducing the risk of treatment failure.
New research reveals that asthma attacks cause overproduction of extracellular proteins and growth of blood vessels in the airways. Over time, these changes lead to constriction of breathing passages, resulting in long-term respiratory issues.
Researchers developed a multi-functional biomaterial that eradicates residual cancer cells, prevents bacterial colonization, and regenerates missing bone tissue. Gallium oxide selectively targets bone cancer cells overexpressing transferrin receptors, causing cell death, while preventing infection in surgical sites.
Scientists discovered a protein secreted by deep-sea extremophile Pyrodictium abyssi that self-assembles into a highly stable biofilm. This discovery opens new avenues for biomedical research and could lead to breakthroughs in wound dressing, medical device coatings, and tissue engineering.
Researchers found that CAR3 coordinates bone formation and regeneration by forming a molecular complex with collagen type I alpha 1 and recruiting bone sialoprotein. The study identified CAR3 as a previously unrecognized regulator of osteoblast differentiation, highlighting its potential for treating bone disorders.
Researchers developed a pH-triggered nanocomposite that synchronizes the release of therapeutic agents, combating bacterial biofilms and oxidative stress. The platform accelerates healing and promotes tissue repair in infected wounds.
Researchers developed a bidirectional interface that uses muscle vibrations to restore natural sensations of movement in upper limb prosthetics. The system restored coordinated hand grasp movement patterns, or 'synergies,' similar to those felt by participants with different kinesthetic feedback systems.
New instruments promise precise measurement and manipulation of tiny nanomaterials used in manufacturing, aerospace and medicine. Researchers can now study the smallest heavy metals with water filters, developing more resilient structures.
Researchers Edward Lemke and Andreas Walther from Johannes Gutenberg University Mainz have been awarded ERC Advanced Grants for their innovative projects, Molecular Shape Microscopy and Protoecologies between Artificial Cells and Mammalian Cells. The grants aim to advance our understanding of protein function in living cells and explor...
Researchers designed artificial proteins that simultaneously form pentagonal and hexagonal arrangements to create virus-like structures. These structures can stably carry drugs, genetic materials, and enzymes within their interior space.
Researchers at Shinshu University discovered a unique surface architecture in the petals of the hardy ice plant that produces glossy appearance. The parabolic ridge structures reflect and concentrate light, creating gloss across a broad range of viewing angles.
Researchers developed a topical gel formulation with 4-aminopyridine to treat burn wounds, achieving near-complete closure in 21 days. The gel delivers the drug directly to the wound site, avoiding systemic risks associated with prolonged use.
Researchers at Chalmers University of Technology developed a new bio-based material using yeast, cellulose, alginate, glycerol, and water. The material can be 3D printed, has customizable properties, and is biodegradable, offering an environmentally friendly alternative to traditional building materials.
Researchers at Institute of Science Tokyo genetically engineer cyanobacteria to produce sulfated polysaccharides, a sustainable route for manufacturing biomaterials. The study demonstrates the feasibility of engineering complex biosynthetic pathways in photosynthetic organisms.
Researchers developed a nanofiber drug delivery system that uses electrospun fiber membranes to deliver multiple drugs in concert, demonstrating improved efficacy against glioblastoma. The system enables localized long-term delivery of drugs directly at the tumor site after surgery.
Researchers summarize how AI is accelerating inorganic biomaterial development for various biomedical applications. AI-powered property prediction and inverse design tools are being used to discover effective materials with unique properties.
The NTU Singapore team developed a tiny seed-sized robot that can perform five surgical functions wirelessly, including cutting and releasing drugs. The robot is controlled by weak magnetic fields and takes under a second to switch between functions. It has the potential to make surgeries more precise and safer.
Researchers at the University of Bath discovered that a fungus can break down hard-to-recycle construction waste and turn it into sustainable insulation. The resulting biomaterial has comparable thermal performance to conventional insulation products with significantly lower carbon emissions.
Researchers developed a new class of stretchy bioelectronics that can stick to biological tissue and relieve hypertension while causing less damage to surrounding tissue. The CaroFlex device uses gentle electrical frequencies to modulate the baroreceptor reflex, providing effective treatment for drug-resistant hypertension.
Scientists at Tampere University created a 3D printed ceramic implant material that closely mimics real human bone. The findings advance personalized bone regeneration and may lead to more effective treatments for bone defects.
Researchers at Washington University in St. Louis have created protein-based materials that can be readily recycled and remade into the same fibers over multiple cycles. These biodegradable fibers, called SAM, are made from genetically engineered microbes and can dissolve in a formic acid solution within seconds.
Researchers have discovered that prickly pear cactus fibers can be extracted and used to create sustainable composite materials. The fibers' natural structure provides a honeycomb-like support system, making them suitable for lightweight, low-load applications.
Researchers discovered that sea squirts package adhesive materials into nanocondensates, which deliver them to the destination and unpack for use. This mechanism is distinct from mussels' adhesion strategy, providing clues for developing bio-adhesives to assist in seaweed cultivation.
A first-in-human trial demonstrates the potential of implantable cytokine factories for treating ovarian cancer, showing a favorable safety profile and encouraging disease stabilization in patients. The therapy successfully activated key immune cells without expanding regulatory T cells, revealing a promising mechanism of action.
Researchers create shape-morphing filaments using rotational multimaterial 3D printing, enabling programmable artificial muscles that bend and twist on demand. The breakthrough could accelerate the development of complex technologies such as soft robotics, energy damping, and biomedical devices.
The collaboration solves a main challenge in ocular wearables by integrating ultra-thin, durable, and stable energy storage. XPANCEO develops smart contact lenses with AR and health monitoring capabilities, while ITEN provides high-power-density solid-state batteries.
Researchers at the Smithsonian National Museum of Natural History analyzed 18 scorpion species and found striking patterns in metal concentration and distribution among their pincers and stingers. The study reveals that zinc plays a role beyond hardness, possibly enhancing durability, and provides insight into how organisms adapt to pr...
Researchers at Tohoku University developed a strong, biodegradable material made from bamboo sheets and PHBH, which can be used to estimate biodegradation in seawater. The material's strength is linked to its degradation rate, providing a predictable usable lifetime for sustainable materials.
Oregon Health & Science University has received significant NIH funding to develop advanced microphysiologic models that mimic how cancers grow and respond to treatment within bone tissues. Two new awards focus on osteosarcoma and prostate cancer, aiming to improve understanding of disease spread and treatment responses.
A new clinical trial at the University of Cincinnati is testing a peptide solution to treat prosthetic joint infections after total knee replacement. The trial aims to reduce the need for repeat surgeries and expand the treatment window beyond two weeks.
Researchers found that extracellular vesicles from menstrual blood stromal cells can improve cartilage function and slow tissue degradation, even in older postmenopausal women. Biomimetic scaffolds are being developed to prolong the effects of these particles, offering a potential cell-free therapy for osteoarthritis.
A team of researchers has achieved a major milestone in developing a new treatment aimed at helping the body repair damaged joints at the source. The experimental treatments have shown promising results in animal models, restoring joint tissue to near-normal levels and significantly reducing pain markers for long periods.
A team of researchers at North Carolina State University has created an injectable microgel called B-knob triggered microgels (BK-TriGs) that can help reduce bleeding in infants during surgery. The microgel works by mimicking the mechanical properties of natural platelets, which helps to create fibrin networks and stanch bleeding.
New research demonstrates that restoring the physical stiffness of the gingival tissue can fundamentally change how cells respond to infection, potentially paving the way for new treatments. The study uses a hydrogel system to investigate how gum tissue stiffness impacts periodontal disease inflammation.
Researchers identify a three-way link between mechanical stress, integrin signaling, and endocytosis in osteoarthritis. Integrin trafficking may help explain why the same pathways have different effects across disease stages and tissue contexts.
The Terasaki Institute for Biomedical Innovation and UCLA Technology Development Group will co-curate an Advanced Organ and Tissue Repair (AToR) session at LABEST, featuring leading experts in regenerative medicine. The session aims to accelerate the translation of breakthrough technologies into real-world clinical solutions.
Researchers at Penn State have developed a new class of tunable biomaterials, known as granular aerogel scaffolds, to support tissue regeneration and vascularization in wound healing. The material offers improved cell infiltration and may help rapidly form new blood vessels and regenerate damaged tissue.
Researchers create living tissue at near-physiological cell density using a new bioprinting strategy called embedded 3D printing in a cell-dense suspension (EPICS). The method enables the precise fabrication of perfusable channels and dense cellular environments, mimicking real organs.
Researchers developed a spray shield that adheres to transplant organs using mussel-derived adhesive protein, reducing immune rejection and its side effects. This innovation enables targeted delivery of immunosuppressants directly to the transplanted site, increasing success rates in xenograft transplantation.
A research team from Xi'an Jiaotong University has developed a method to align cells in muscle tissue using electric forces during electrohydrodynamic bioprinting. This breakthrough allows for the creation of living muscle tissues with tightly aligned cells, enabling the production of functional muscle constructs.
Researchers introduce Fe₃O₄@mPEG-Ag nanoparticles as a non-antibiotic strategy to combat drug-resistant bacteria. The novel nanomaterial demonstrates strong antibacterial activity against clinically relevant multidrug-resistant strains.
Researchers at UNLV have created a 3D-printed synthetic California sea lion pelvic region, enabling medical professionals to conduct blood collection training on anatomically authentic models. This innovation has the potential to improve veterinary procedures and benefit human lives in the long run.
Researchers from the University of Ottawa have developed a groundbreaking biomaterial that combines strength, adaptability, and biological compatibility for soft tissue repair. The hydrogel is made from synthetic peptides and can be precisely tailored through chemical design, making it an attractive alternative to existing biomaterials.
Researchers at Tokyo Metropolitan University have created a neutral molecule that can carry DNA into biological cells using a process called annealing. This breakthrough promises more effective therapies by reducing inflammation and improving delivery efficiency.