Articles tagged with Biomaterials
Researchers at KTH Royal Institute of Technology created a 3D model of living brain cancer using cavitation molding technique. The model closely replicates human tissue and maintains cell viability, making it suitable for drug screening.
Researchers develop a novel nanoplatform that can deliver drugs directly to T cells, which play a crucial role in immune reactions. The platform uses pH-sensitive dendrimers with phenylalanine and has shown promising results for cancer immunotherapy.
Researchers developed novel bioplastics using lysine-rich proteins, offering improved durability, biocompatibility, and biodegradability. The bioplastics can be produced without toxic chemicals or complex processing steps, making them a promising alternative for packaging, toys, and other applications.
Researchers developed a self-cleaning bioplastic that repels liquids and dirt like a lotus leaf, breaking down rapidly in soil. The bioplastic is made from cheap raw materials, compostable, and suitable for fresh food and takeaway packaging.
Researchers have developed a prototype insulin-loaded patch that comfortably sticks to the inside of a person's cheek, offering a less invasive way to manage blood sugar levels. The patch, activated by heat, releases insulin into the bloodstream several times faster than through skin, showing promise for diabetes treatment.
Researchers have discovered how carbohydrates interact with lignin in plant biomass, revealing new information on the organization of lignin-carbohydrate interfaces. This discovery can help advance technology for using biomass as a renewable resource for energy and materials.
Researchers have developed a cream that prevents frostbite injuries in mice when applied to the skin before severe cold exposure. The cream, called SynAFP, reduces frostbite wound size and speeds healing compared to no treatment. Further studies are needed to determine its effects on humans.
Researchers use matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) to track injected collagen in the heart. The technique allows for precise detection of therapeutic peptides and their distribution in the myocardial infarct.
Researchers have developed a combination of materials that can morph into various shapes before hardening, similar to the natural process of bone development in the human skeleton. The soft material can be used to create microrobots that can inject themselves into complicated bone fractures and expand to form new bone.
Silk's unique properties make it a promising material for biomedical devices, wearable sensors, and optics. The researchers aim to harness its versatility for future technologies, including reducing food waste.
Scientists from Tokyo Medical and Dental University create polyrotaxane-based biomaterials that improve epithelial cell-cell adhesion, enabling the repair of damaged tissues. The study suggests a potential application in clinical dentistry for treating periodontal disease.
Scientists have created a versatile carbon-loaded shellac ink suitable for disposable printed electronics. The ink achieves high electrical conductivity while maintaining stability and biodegradability. Its practical applications include conductive tracks and sensor elements in sustainable devices.
Researchers at NTU Singapore have developed a new use for e-waste plastics by repurposing them as an alternative to laboratory cell culture containers. The team found that over 95% of human stem cells seeded on e-waste plastics remained healthy after a week, comparable to cells grown on conventional plates.
A flexible and easy-to-use micropen setup is capable of directly writing on surfaces to a microprecise level. The device allows for the printing of microarrays, lines, curves, and other structures in real-time using biomaterial or conductive ink.
Researchers at A*STAR's Institute of Molecular and Cell Biology have discovered a novel protein therapy using Agrin to promote wound healing and repair. The study found that timely induction or exogenous supplementation of Agrin accelerates the healing process, preserving the mechanical architecture of injured skin layers.
Researchers at McGill University create injectable hydrogel that forms stable structure allowing cells to grow and repair injured organs. The material's toughness and porosity make it suitable for heart, muscle, and vocal cord repair.
Researchers at RCSI University of Medicine and Health Sciences have developed a new method to enhance wound healing using 3D printing of platelet-rich plasma. The technique showed promising results in improving vascularisation and reducing fibrosis, leading to faster and more successful wound healing.
Scientists at Washington University in St. Louis have created a biocompatible adhesive hydrogel that can stick to various surfaces underwater, with properties similar to natural mussel foot protein and spider silk. This breakthrough has potential applications in tissue repair, particularly for tendon-bone repair.
Researchers at the University at Buffalo have created model protein-RNA droplets with properties similar to those of viscoelastic Maxwell fluid and Silly Putty. These droplets exhibit dual behavior, acting like both elastic solids and viscous liquids, depending on the timescale.
Researchers have found a cheaper and easier way to create large groups of carbon nanotubes without lithography. The 'dewetting' process allows for precise arrangement of nickel catalyst particles to form hexagonal nanotube arrays.
McGill researchers have discovered how bacteria create cyanophycin granules, a reserve of nitrogen and energy. The study uses cryo-electron microscopy and X-ray crystallography to visualize the active enzyme in action, opening up possibilities for biotech applications.
A new pouch device has been developed to protect transplanted human liver cells from immune systems for up to six months, producing crucial biomolecules. This breakthrough offers a potential path toward treating human diseases without needing to suppress the patient's immune system.
Researchers create a novel magnetoelastic generator that can convert human body motions into electricity, outperforming existing technology. The device is flexible, waterproof, and generates significant electrical currents, opening up new avenues for wearable and implantable diagnostic sensors.
Jochen Zimmer, a UVA professor, has been awarded $9 million by the HHMI to pursue his research on biopolymer transport across biological membranes. His work aims to develop new biomaterials for medicines, food, and energy, potentially combating diseases, hunger, and climate change.
A chemical engineer is developing a novel biomaterial that can mimic the response of pediatric brain cancers to different approaches, allowing for customized treatment plans. The material will be designed to simulate the growth environment of cancer cells inside a tumor and can be used with patient-derived cells.
Researchers aim to replicate natural tendon development using embryonic chicken and mouse models, with a focus on mechanical stimulation and nanoparticle design.
A University of Kansas researcher is investigating how estrogen interacts with cells to promote tissue repair and regeneration after injury. The study aims to understand why male and female tissues regenerate differently, which could lead to the development of new tailored therapies.
The study found that a specific type of glycosaminoglycan in the scaffold led to greater blood vessel development and immune cell activation. Researchers aim to further understand these interactions to develop biomaterials for bone repair.
Researchers discovered that insects like scorpions and ants use zinc- and manganese-enriched materials to create sharp edges, allowing them to penetrate tough skin with less force. This biomaterial property enables small organisms to obtain food with smaller muscles and less energy.
A recent study reveals that ants, worms, spiders, and other tiny creatures have a built-in set of tools that maximize cutting efficiency thanks to the arrangement of individual atoms of zinc. This biomaterial allows animals to use less force, making their smaller muscles spend less energy.
Researchers from Terasaki Institute for Biomedical Innovation develop methods to enhance mechanical properties of hydrogels, including toughness, stretchiness, and adhesive strength. By introducing dopamine and alkaline conditions, they create gel-like materials with improved biocompatibility and regenerative capabilities.
Researchers created a polymer coating that releases Lasioglossin-III, an AMP with broad-spectrum antibacterial activity, targeting specific infectious bacteria and preventing airway complications. The coating demonstrated significant antibacterial activity and prevented bacterial adherence to the tube.
Researchers found that local delivery of tumor-specific T-cells is an efficient option to convert tumors unresponsive to checkpoint inhibitors to permit tumor cures. Locally delivered T-cells showed similar control of established tumors as intravenous adoptive T-cell transfer.
A new research project aims to create strong, malleable biomaterials that support stem cell growth for improved skull reconstruction surgeries. The $2.4 million grant will help accelerate bone regeneration and reduce complications.
Rice University bioengineers are developing an insulin-producing implant to regulate blood glucose levels in Type 1 diabetics. The implant uses human stem cells and 3D printing to mimic the natural behavior of the pancreas, with the goal of achieving consistent target blood glucose levels.
Alvaro Della Bona, University of Passo Fundo Professor, received the 2021 Wilmer Souder Award for his contributions to dental biomaterials research. He is recognized internationally for his publications and invited presentations on the topic.
The IADR/AADR presented awards to researchers in three categories: Biological Research, Biomaterials & Bioengineering Research, and Clinical Research. The winners were recognized for their contributions to advancing dental health and well-being worldwide.
Scientists at the University of Leeds have developed an approach to control the structure and mechanics of synthetic biomaterials made from proteins. By removing specific chemical bonds, known as 'protein staples,' they altered the structure of a protein network, resulting in different mechanical properties.
Researchers develop a de novo peptide Y15 that readily forms secondary structures to enable bottom-up synthesis of functional protein assemblies in live cells. The peptide enables the formation of fibrous structures and clusters in test tubes and live cells, facilitating protein assembly and reconstitution of natural complexes.
Researchers at NYU Tandon School of Engineering developed stimuli-responsive coiled-coil fibrous hydrogels that can be triggered by temperature, pH, or light. These smart biomaterials have potential for tissue engineering, drug delivery, and wound healing applications.
A team of researchers from Japan discovered that high COOH concentration facilitates internal proton transport while lower concentrations favor interfacial transport. The study may contribute to developing bio-conductive materials for biological devices and eco-friendly fuel cells.
A research team has developed an in vitro diseased skin model that displays the pathophysiological hallmarks of type 2 diabetes using 3D cell printing technology. The model exhibits slow re-epithelialization, insulin resistance, and pro-inflammatory response, similar to diabetic skin.
Scientists have developed a new biomaterial that regrows both blood vessels and bone, potentially providing an alternative to current systems. The biomaterial was inspired by the natural way in which bone defects regenerate and uses a mechanobiology-informed approach to promote both angiogenesis and osteogenesis.
Researchers develop a 3D biomaterial scaffold that slowly releases stem cells, reducing dosages and improving therapeutic effects in mice with osteoarthritis. The cryogel 'sponge' ensures implanted stem cells stay in the knee joint area longer, allowing for more effective treatment.
A new biomaterial, a boron-loaded alginate hydrogel, has been designed to accelerate muscle regeneration after injury. The hydrogel stimulates integrins, which promotes tissue formation and reduces recovery time by half.
Scientists have identified a polymer with fine-tuned mobility properties that alter the immune activity of specific liver cells, offering potential for regenerative medicine. The study found that surface mobility significantly affects the movement and gene expression profile of Kupffer cells.
Northwestern University researchers create novel biomaterial that enhances neuron growth, a crucial finding for regenerative medicine. The material's bioactive properties allow cells to penetrate and interact with bioactive signals, potentially treating neurodegenerative diseases such as Parkinson's and Alzheimer's disease.
Researchers have developed a thermoplastic biomaterial that can be controlled to degrade at varying rates and maintain mechanical properties. The material is suitable for soft tissue repair or flexible bioelectronics and has been shown to promote healthy tissue growth.
A team of scientists has developed objects made with living materials, using fungi as a key component. The research demonstrates that fungi can sense and process various external stimuli, including light, temperature, and electrical signals, making them suitable for creating sustainable smart wearables.
Researchers have identified a rare genetic bone disorder by using precision medicine strategies, uncovering mutations in the LAMA5 gene that cause extreme bone fragility and skeletal deformity. The study also revealed a new signaling pathway governing skeleton formation, which could be used for common bone conditions.
Researchers develop a biomaterial that enhances adult stem cell regenerative ability, repairing large bone defects and reducing inflammation. The material incorporates nanoparticles that activate JNK3, a key driver of children's stem cells' regenerative capacity.
Scientists at the University of Nottingham have developed a new protein imaging method that allows for the accurate analysis of biomaterials and tissue. This breakthrough technology has the potential to lead to the development of more effective drug delivery systems and medical devices.
A new species of spider, Ocrepeira klamt, has been discovered by a University of Bayreuth researcher in the highlands of Colombia. The spider differs from related species in its reproductive organs and is native to an altitude of over 3,500 meters above sea-level.
Researchers at Northwestern University have synthesized a new form of melanin enriched with selenium, called selenomelanin, which shows promise as a shield for human tissue against harmful radiation. The new biomaterial offers better protection than traditional forms of melanin and has potential applications in space travel
Researchers are developing biomaterials to boost the body's natural healing process, with two approaches: incorporating cells or designing materials to stimulate cellular response. This can lead to improved success rates in tissue regeneration, reducing regulatory barriers and increasing available options.
Researchers at the University of Birmingham have created a new thermoplastic biomaterial with shape memory properties, enabling it to be stretched and molded but reforming into its original shape when heated. The material offers a stable, long-lasting option for medical devices such as bone replacements.
Scientists at RCSI University of Medicine and Health Sciences have developed a biomaterial that promotes an immune response to encourage repair and lowers the risk of inflammation in damaged bone tissue. The technology is designed to deliver microRNA silencers, increasing cells responsible for bone repair.
A collaborative research team has developed a multi-component biomaterial-based screening approach that identifies material compositions and mechanical stimuli enabling human stem cells to differentiate into cells capable of generating higher-quality articular cartilage. The study uses high-throughput screening with multiple combinatio...
A new bone-graft biomaterial supercooled before application could eliminate pain and improve smile outcomes for dental patients. The material, combining octacalcium phosphate with collagen, has shown superior bone regenerative properties compared to earlier substitutes.
A team of microbiologists at the University of Bayreuth created a modular system for genetic reprogramming of bacteria, turning them into cell factories for multifunctional magnetic nanoparticles. These nanoparticles combine various useful functions and properties, offering a promising new material in biomedicine and biotechnology.