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Duplicate or mirror?

Scientists have discovered that the direction of laser light hitting a molecule determines its chiral form. This breakthrough could lead to more efficient production of molecules with uniform chirality for pharmaceuticals. The research was conducted using the planar formic acid molecule and the reaction microscope method.

SourceGoethe University Frankfurt·JournalScience Advances·DateMar 14, 2019

Righty or lefty, as you like

Researchers developed a new iridium catalyst for the selective synthesis of chiral lactams, which are key building blocks in pharmaceutical agents. The catalyst achieves high selectivity by inducing hydrogen bonding between substrate and catalyst, leading to the production of desired compounds with minimal waste.

SourceInstitute for Basic Science·JournalNature Catalysis·DateFeb 21, 2019

Lefty or righty molecules lend a hand to material structures

Researchers at Rice University have created chiral polymers that can enable materials with unique properties, such as optical and sensing capabilities. The discovery could lead to the creation of metamaterials with tunable properties, including tough-but-flexible compounds with distinct functions.

SourceRice University·JournalProceedings of the National Academy of Sciences·DateFeb 11, 2019

Weyl goes chiral

Physicists at ETH Zurich have created acoustic metamaterials that interact differently with Weyl fermions of opposite chirality, a crucial aspect of particle physics. This discovery enables the manipulation of chiral channels, giving independent access to these particles in bulk systems.

SourceETH Zurich Department of Physics·JournalNature Physics·DateFeb 11, 2019

New synthesis strategy for chiral drugs -- versatile chiral chemical species from aldehydes

Researchers at Kanazawa University have developed a new synthesis strategy for chiral drugs by harnessing the potential of aldehyde-derived chiral hydroxycarbanions. This breakthrough enables the selective production of one enantiomer of chiral molecules, paving the way for the creation of complex drugs with desired chirality.

SourceKanazawa University·JournalJournal of the American Chemical Society·DateJan 9, 2019

Chirality switching in biomineral structures

Researchers have discovered a method to synthesize helical biomineral structures with opposite spiral directions by adding specific amino acids, shedding light on how certain biological structures can exhibit both rotations within the same species or individual organism.

SourceMcGill University·JournalScience Advances·DateAug 1, 2018

Organ regeneration is no longer a distant dream

Researchers at Osaka University have clarified the cellular mechanism behind left-right asymmetric organ morphogenesis using live imaging and computer simulations. The team discovered that 'cell sliding' is essential for this process, which may lead to breakthroughs in regenerating organs with tubular structures.

Twisted meta-molecules as they really are

Researchers have devised a highly sensitive method to test the chirality of materials, overcoming false positives from competing effects. By using twisted meta-molecules, they separated chirality from sources of error, allowing for accurate measurement and potential applications in fields like telecommunications and pharmaceuticals.

SourceUniversity of Bath·JournalACS Nano·DateJun 26, 2018

A sea of spinning electrons

Scientists have discovered a 'chiral spin mode' - a sea of electrons spinning in opposing circles that can transport information with little energy dissipation. This breakthrough paves the way for building novel electronic devices such as computers and processors with reduced energy loss.

SourceRutgers University·JournalPhysical Review Letters·DateOct 2, 2017

New porous solids may lead to better drugs

A new discovery in chemistry could lead to more specific and desired forms of drugs, with the creation of chiral molecular sieves that can sort and create left- and right-handed molecules. This breakthrough has broad implications for pharmaceutical companies and may improve medications such as ibuprofen.

SourceCalifornia Institute of Technology·JournalProceedings of the National Academy of Sciences·DateMay 1, 2017