Researchers have created a biomimetic mineralized layer that replicates the structure of natural tooth enamel, exhibiting increased nanohardness and surpassing the natural tissue in terms of strength. The new material can be used to restore or repair damaged enamel due to abrasion, erosion, or improper diet.
Researchers develop a safe and effective way to whiten teeth without damaging enamel, breaking apart cavity-forming biofilms. The treatment uses a hydrogel activated by green light to kill 94% of bacteria in biofilms and prevent cavities from forming on teeth.
Researchers at KU Leuven and UHasselt have created a 3D model with human dental stem cells that can produce enamel components, paving the way for biological dental enamel repair. This natural alternative has the potential to reduce risk of tooth necrosis and improve patient outcomes.
A study found that childhood cancer survivors who received combined chemotherapy and radiotherapy have a higher risk of dental developmental anomalies. The first signs of dental disturbances can appear within one or two years after treatment. Researchers identified specific treatments and age factors associated with increased DDA risk.
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Researchers developed a new tooth whitening treatment using synchrotron light, showing improved application time needed, efficiency, and safety. The treatment, which uses reduction via metabisulfite, promotes lower concentrations and shorter application times, reducing side effects.
Researchers created a dental tool that measures plaque acidity using an LED light and FDA-approved chemical dye, providing dentists with early warning signs of cavity development. The device can help limit the need for specific harmful bacteria tests and educate patients about sugar's impact on oral health.
This symposium explores the effects of environmental influences on enamel formation, including early life adversity, endocrine disruptors, and genetic susceptibility. Researchers highlight the importance of enamel as a biomarker for exposure to environmental stressors, potentially leading to increased dental disease risk.
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Gorgonopsians, a lineage more related to humans than dinosaurs, evolved the first complex tooth serration made of enamel and dentine, discovered in a new Harvard-led study. This finding indicates that gorgonopsians developed this specialized structure early in amniote evolution.
Paleontologists found that different types of mineral dust cause distinct signs of wear on plant-eating vertebrates' teeth. Larger quartz particles caused severe abrasion, while small particles generated smooth surfaces. This study improves diet reconstruction accuracy using fossil teeth analysis.
KAIST researchers used AFM to analyze the effects of acidic and sugary drinks on human tooth enamel at the nanoscale level. The study found significant increases in surface roughness and decreases in elastic modulus with immersion time, highlighting the need for thorough studies on early-stage enamel erosion.
A collaboration between Cornell and Northwestern universities has exposed tiny chemical flaws in human enamel using atomic imaging techniques. The findings suggest that irregularities in the enamel's structure may play a role in reinforcing it, making it more resilient to decay.
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Materials scientists at Northwestern University have discovered a small number of impurity atoms that contribute to the strength but also make human enamel more soluble. The study, using atomic-scale resolution, sheds light on the spatial distribution of these impurities in the enamel's core-shell structure.
A NIH-funded study has revealed unprecedented atomic details of human tooth enamel structure and composition, including the presence of minor elements such as magnesium and sodium. The findings suggest that these irregularities may introduce areas of strain in the crystallite, potentially making enamel stronger overall.
A new study reveals that the Late Cretaceous reptile Priosphenodon had a unique type of tooth enamel, similar to that of mammals, which provided it with resilience against tooth wear. The researchers found that the enamel crystals in Priosphenodon were 'woven' into long threads called enamel prisms, a characteristic also found in mammals.
Researchers at NYU College of Dentistry discovered that excessive fluoride causes dental fluorosis by altering calcium signaling, mitochondrial function, and gene expression in tooth enamel cells. This understanding provides a promising mechanistic view of how fluorosis arises.
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Researchers developed a bioactive peptide that coats tooth surfaces to prevent cavities and heal existing ones. The peptide inhibits bacterial adhesion and promotes remineralization, offering a potential new strategy for treating tooth decay.
A new study from Washington University in St. Louis suggests that early human ancestors could have eaten hard plant foods like nuts and seeds without causing damage to their teeth. The researchers used experiments on modern tooth enamel to demonstrate that even the hardest plant tissues barely influence microwear textures.
Researchers at Berkeley Lab have made significant strides in developing a novel cancer drug that targets KRAS gene mutations, as well as chelating heavy metals with artificial proteins. Additionally, scientists have discovered a natural mechanism in human tooth enamel that prevents cracks from forming, allowing teeth to last a lifetime.
A team of scientists has discovered ancient fossil teeth in the Yukon, which are believed to belong to a long-extinct cousin of modern rhinoceroses. The discovery provides a gap in the fossil record and sheds light on the migration patterns of animals during the Tertiary Period.
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A study from King's College London found that sugary soft drinks are associated with both obesity and tooth wear among adults. The acidic nature of these drinks leads to tooth erosion, particularly in obese patients. This highlights the importance of monitoring calorie intake through acidic sugar-sweetened drinks.
Researchers have extracted almost complete sets of proteins from ancient dental enamel, allowing scientists to reconstruct molecular evolution beyond the usual DNA preservation limit. This breakthrough enables scientists to study hundreds of species, including humans, and could revolutionize our understanding of the world's evolution.
Researchers at the University of Missouri found that crocodiles have thin tooth enamel, unlike humans and other hard-biting species. This discovery could lead to new approaches for dealing with people's teeth.
The article highlights the impact of fluoride on reducing dental caries, citing studies that showed a marked reduction in caries experience in fluoridated cities compared to non-fluoridated control cities. The widespread use of fluoride toothpaste has also been credited with improving oral health and quality of life for populations wor...
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Researchers used microscopic images to differentiate between carnivores and herbivores among lepidosauria species. Fine distinctions were made between algae-, fruit-, and mollusk-eating species, pointing towards the discovery of first herbivorous terrestrial vertebrates.
Researchers at University of Helsinki and Aalto University developed a new model to explain tooth enamel formation, proposing that differences in enamel thickness are regulated by nutrient diffusion rates. This discovery helps uncover why human and orangutan teeth have distinct characteristics.
A study led by NYU Dentistry researchers reveals that a mutation in the ORAI1 gene causes calcium deficiency in enamel cells, leading to defective dental enamel mineralization. The study identified ORAI1 as the dominant protein for calcium influx and provided insights into the mechanisms by which calcium affects enamel cell function.
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Two new genes, ENAM and ACP4, have been identified as causative variants in canine enamel development defects. The study reveals that these genes are also associated with human enamel development disorders.
A study by Otago researcher Dr Carolina Loch and colleagues has shed new light on the evolution of modern baleen whales' ancestors, revealing complex enamel structures in their teeth. The research suggests that these ancestral whales had a mix of mammalian and whale-like characteristics.
Research team finds that plant phytolith and water content cause differing degrees of tooth enamel abrasion in vertebrates. The study suggests that tooth wear can be used to reconstruct the dietary behavior and habitats of extinct animals, with implications for paleontology.
A study on Changchunsaurus parvus reveals unique features in its teeth, including wavy enamel and a method of tooth replacement that allowed for continuous shearing surface formation. These findings suggest early adaptations for herbivory in this small herbivorous dinosaur.
A recent study by British American Tobacco found that e-cigarettes and tobacco heating products significantly reduce enamel discoloration compared to conventional cigarettes. The researchers assessed the impact of these products on teeth using an in vitro study and found minimal staining.
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Researchers discovered that MMP20, an enzyme essential for tooth development, degrades the basement membrane to initiate enamel formation. The study's findings suggest that MMP20 plays a crucial role in regulating tooth growth and may be involved in various dental disorders.
Researchers have discovered that an increase in certain substances in oral fluid can indicate caries development. They found a way to prevent the disease by analyzing changes in saliva composition, enabling early detection and treatment.
Researchers at Queen Mary University of London have developed a new method to create materials with remarkable precision and order, resembling dental enamel. This breakthrough could lead to the prevention and treatment of tooth decay and sensitivity, benefiting over 50% of the world's population.
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Researchers at the University of Washington have designed a convenient and natural product that uses proteins to rebuild tooth enamel and treat dental cavities. The new technology restores mineral structure found in native tooth enamel, enabling daily use as part of preventive dental care routine.
A study found that none of nine analyzed toothpastes mitigated enamel surface loss, a key factor in tooth erosion and dentin hypersensitivity. Researchers stress the importance of proper dental treatment, diet, and lifestyle changes to prevent these problems.
Researchers question the longstanding guidelines for fluoride intake, citing changes in sources and prevalence of dental caries and fluorosis. The symposium highlights research gaps, including measuring total fluoride intake and evaluating its effects on children and adults.
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Researchers have developed a smart coating that mimics the structure of human skin, offering a balance between strength and self-healing capabilities. The coating, composed of polyvinyl alcohol and tannic acid, can heal itself like skin when cut and also kill bacteria.
Researchers developed a method to determine human sex from tooth enamel using peptides. The approach successfully identified sex chromosome-linked isoforms of amelogenin, an enzyme-forming protein, from acid-etched samples, confirming sex in archaeological and legal contexts.
A mutation in the SCL24A4 gene is identified as the cause of enamel hypoplasia in Samoyed dogs, leading to discolored and malformed teeth. The study found that breeders can eliminate the faulty gene through selective breeding.
Caries-causing bacteria survive in dental plaque thanks to EPS' calcium integration, which neutralizes toxins and strengthens the biofilm. This process inhibits enamel remineralization, contributing to caries development.
This study evaluated the effects of fluoride bleaching agents on human enamel. It found that fluorine bleaching agents increased the concentration of fluorine, calcium, and phosphorus ions in the enamel without altering its microhardness.
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The researchers created a synthetic version of tooth enamel to improve resilience in rigid structures. They successfully mimicked its properties through layering and polymerization, demonstrating that this material can absorb vibrations effectively.
Mutations in specific proteins affect tooth enamel formation, leading to increased risk of caries. The study's findings open up new possibilities for preventing caries in patients with defective tooth enamel.
Researchers at NYU Dentistry are studying calcium control in dental enamel to develop improved strategies for preventing and treating dental caries. The goal is to understand how changes in calcium levels affect enamel mineralization and develop clinical techniques to replicate these processes.
Researchers found a benign tumor, called a compound odontoma, in a fossilized gorgonopsian jaw from 255 million years ago. The discovery suggests that this type of tumor may have existed before the first mammals evolved.
Researchers from the University of Sydney have created three-dimensional maps showing the positions of atoms critical in the decay process using atom probe tomography. The study reveals magnesium-rich regions between hydroxyapatite nanorods, which play a key role in governing tooth behavior.
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Researchers used dentistry techniques to analyze fossil and modern teeth, finding similarities between ancient walruses and modern pinnipeds. The findings suggest that the ancient walrus was unlikely to feed on large prey, contradicting previous claims of a 'killer walrus' diet.
Researchers studied skeletons from London's St. Mary Spital cemetery, finding that stress markers like LEH were correlated with famine deaths. However, periosteal lesions on shin bones were found to be associated with normal, non-famine related deaths, contradicting previous assumptions about their significance.
Researchers at USC discover enzyme MMP-20 that can regrow tooth enamel, reducing lesions by up to 70%. The breakthrough could lead to a new treatment option for tooth decay and sensitivity.
A NYU research team led by Dr. Rodrigo Lacruz has discovered the mechanism of calcium transport essential for dental enamel formation. The study found that CRAC channels play a critical role in controlling calcium uptake, which is necessary for enamel crystal growth.
Researchers from Uppsala University and IVPP in Beijing combined palaeontological and genomic data to determine that enamel originated in the skin and colonized the teeth much later. The study found that ganoine, an enamel-like tissue, is expressed in the skin of certain fish species, suggesting a possible connection between the two.
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A recent study reveals a significant association between hair disorders and susceptibility to dental caries. The research found that polymorphisms in hair keratins are associated with increased risk of dental defects and caries, highlighting the importance of keratin components in tooth enamel structure.
A cross-sectional study of 1,309 children found a significant association between low birth weight and the development of enamel defects. The study suggests that prenatal hypertension and prematurity may also contribute to the severity of these defects.
A study by Bernhard Ganss and colleagues found that amelotin is essential for enamel mineralization and maturation. Ammelotin-deficient mice exhibited weak incisor-edge enamel that fractured and chipped, with delayed enamel mineralization and retention of organic matrix.
Researchers discovered beaver teeth have a harder, more resistant form of enamel built with iron that surpasses fluoride-treated enamel in acid resistance. This finding could lead to better understanding of human tooth decay and improvement on current treatments.
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Scientists developed a novel paste based on calcium and phosphorus to address tooth sensitivity, which can lead to more serious dental problems. The new material plugs exposed tubes more deeply than other treatments, providing longer-lasting relief.
Research reveals that human incisors grow quickly in the second trimester of fetal development, allowing them to erupt at six months. This rapid growth is thought to be an adaptation for early weaning, as it enables babies to transition from breast milk to solid foods sooner.
A new study published in the Journal of Clinical Investigation has found a significant link between hair keratin mutations and an increased risk of dental decay. Individuals with mutations in hair keratin genes are prone to cavities, with abnormal tooth enamel structures contributing to weakness.
A University of Florida study found that trace amounts of lead in human teeth can provide clues about a person's geographic origin. The discovery could help law enforcement solve cold cases by focusing investigations on specific regions based on the type and amount of lead isotopes present.