Articles tagged with Nanoparticles
A Vanderbilt University team developed a nanoparticle to target tumor-infiltrating immune cells and activate the STING pathway, a natural mechanism to mount an immune response against cancer. The breakthrough offers hope for patients who don't respond to checkpoint blockade therapies.
Scientists have identified natural antibodies within protein corona that trigger immune system response to nanoparticles. Depleting these antibodies reduces complement system activation, enabling safe delivery of cancer-fighting drugs and imaging agents.
Researchers developed a new catalyst composed of platinum and nickel, which is more efficient than pure platinum. The study used ultrabright x-rays to reveal the growth pathway and chemical characterization of the nanoparticles in real time.
Researchers at Virginia Tech have developed a novel drug delivery system that uses attenuated bacteria cells to transport anti-cancer drugs directly to cancer sites, showing up to 100-fold improvements in distribution and retention. This innovative approach has the potential to revolutionize cancer treatment options.
Researchers found unexpected chemical compositions in 'magic nanoparticles' that display enhanced stability, including Fe6O4 and Ce3O12. The study also reveals oxygen-rich nanoparticles may explain carcinogenicity of oxide nanoparticles.
This study introduces a green method for synthesizing benzopyrano and xanthenol compounds using TiO2 nanoparticles as catalysts. The reaction is carried out in aqueous medium at room temperature, yielding high yields (92-98%) within short reaction times.
A new study at Northwestern University has developed a revolutionary tool to rapidly test millions of nanoparticles for specific applications. The novel approach utilizes a combinatorial library, or megalibrary, of nanoparticles and an in situ Raman spectroscopy-based screening technique to identify optimal compositions.
Lipid nanoparticles have shown promise in delivering drugs to the brain due to their ability to cross biological barriers. By modifying their surface, these particles can effectively target brain cells and increase drug efficiency.
Researchers developed a novel solid lipid nanoparticle (SLN) formulation using Vitamin E TPGS and glyceryl mono-oleate to enhance the delivery of vinorelbine bitartrate, improving its anticancer efficacy. The SLNs showed a biphasic release pattern and were 39.5 times more effective than the original drug.
Researchers developed a new device to measure and control an optically trapped nanoparticle's motion with subatomic resolution. The device uses a light-guiding nanoscale device to monitor the particle's position with unprecedented sensitivity.
Researchers from NUST MISIS developed a new hybrid catalyst for carbon monoxide oxidation using hexagonal boron nitride and silver nanoparticles, achieving full conversion at 194 degrees Celsius. Increasing silver concentration may reduce the temperature further.
Researchers developed a novel method to adjust catalyst nanoparticle size during continuous flow, optimizing chemical reactions and reducing testing time. The technique improved the performance of metal-carrier catalysts, producing desired compounds with specific properties.
Researchers at Far Eastern Federal University found that arc welding produces toxic nanoparticles in the air, which can be inhaled through the respiratory system. The particles contain metal oxidation products, particularly those with diameters under 1 nanometer, and can translocate to the central nervous system.
A new Australian study has provided direct evidence that zinc oxide nanoparticles do not penetrate human skin or cause cellular toxicity after repeated application. The findings support the use of ZnO nanoparticle sunscreens, outweighing perceived risks and improving consumer confidence in these products.
A groundbreaking study found that billions of nanoplastics can accumulate in the bodies of marine organisms like great scallops within just six hours. The research, led by the University of Plymouth, showed that even smaller particles measuring 20nm had become dispersed throughout the body's organs.
Researchers at FAU have developed a new method for measuring the length and diameter distribution of plasmonic gold nanorods in one single experiment. The method combines multi-wavelength absorption optics and analytical ultracentrifugation, allowing for accurate analysis of nanoparticles in dispersions.
Researchers at City University of Hong Kong have developed a novel strategy to create high-strength alloys that are also extremely ductile and flexible. The breakthrough solution involves massive precipitation of nanoscale particles, solving the critical issue of the strength-ductility trade-off dilemma.
A team of McGill researchers has created a phosphorus-free anti-scaling solution based on hairy nanocellulose, providing an effective and environmentally friendly alternative to traditional methods. The breakthrough uses negatively charged carboxyl groups on cellulose nanoparticles to control scale formation.
Researchers from ITMO University developed a method to enhance enzyme activity using radio frequency radiation, resulting in acceleration of enzymatic processes. The technique uses magnetic nanoparticles to adsorb radio emission and convert it to heat, stabilizing the enzyme and allowing for remote control of biochemical systems.
A new study led by the University of Queensland and University of South Australia found that zinc oxide nanoparticles used in sunscreen do not penetrate the skin or cause cellular toxicity after repeated applications. The research refutes widespread claims about the safety of nanoparticulate-based sunscreens.
Researchers develop new method for selectively binding proteins to nanoparticles using co-assembling points of contact, promising applications in diagnostics and medicine. The method has potential for treating diseases such as Alzheimer's by dissolving amyloid aggregates.
Scientists at Nagoya Institute of Technology create raspberry-shaped nanoparticle that converts toxic carbon monoxide into harmless carbon dioxide. The unique surface nanostructure improves low-temperature CO oxidation activity and holds promise for future applications in catalysis.
A genetically programable strain of yeast fueled by light-harvesting nanoparticles can efficiently convert carbon into high-value chemicals. This new biohybrid system overcomes existing limitations in bioinorganic systems, offering a promising method for producing high-value chemicals.
Researchers at Rice University have developed a new technology that uses a moth-infecting virus and nanomagnets to deliver CRISPR/Cas9 payloads for gene editing. The therapy has the potential to treat genetic diseases such as sickle cell, muscular dystrophy, and cystic fibrosis.
Researchers developed stealth-cap technology to increase stability and biocompatibility of light-transducing nanoparticles. The new nanoparticles are water-soluble, stable in complex body fluids, and can store medications like cancer drugs.
Researchers at the University of Edinburgh developed a cost-effective method to create high-performance energy devices and diagnostic tests using nanoparticles. The electrospinning technique, which produces nanofibres with high surface area, has been successfully tested in fuel cell applications.
A new anti-thrombosis drug based on magnetite nanoparticles has been developed by ITMO University researchers. The drug successfully passed preclinical testing, showing a 20 times shorter clot dissolution time and a lower minimum dose required to achieve the therapeutic effect compared to traditional medications.
Researchers at Stanford University have developed a new technique to study individual nanoparticles undergoing photocatalytic reactions. The method, published in Nature Communications, uses a custom-designed specimen holder and mirrors to focus light onto the nanoparticle, allowing scientists to observe the reaction as it unfolds.
Researchers develop silver nanoparticles coated with anti-seizure drugs to kill brain-eating amoebae, increasing human cell survival rates. The drug-nanoparticle combos target protein receptors or ion channels on the amoeba's membrane, offering a potential treatment for deadly infections.
Drexel researchers have developed a polymer coating that helps nanoparticles evade the immune system and liver, allowing them to remain in circulation for longer periods. The mushroom-brush layer combination enables nanoparticles to reach cancerous tumors more effectively.
A team of researchers has discovered a noble metal-free catalyst system that is as active as platinum, thanks to the high entropy effect. The alloy, made up of five elements, forms new active centers that offer entirely new properties and are relevant for catalysis.
Zinc oxide nanoparticles exhibit antibacterial, anticancer, and antioxidant effects, but also induce toxic effects on various organs and systems. Their concentration-dependent toxicity highlights the importance of determining efficacy and safety.
Perovskite nanoparticles are capable of emitting different colors depending on the internal halogen element. Researchers at UNIST developed a simple method to replace certain elements via solution process, allowing for the creation of red, blue, and green LEDs with high luminous efficiency.
A joint research team has discovered a new analysis method that reveals nanoparticles continue to grow and transform into bulk materials in the early stages of nanomaterial growth. This finding contradicts classical nucleation theory, which assumes critical nuclei are created early in material growth.
Researchers have created a more efficient path to producing solar fuels by enticing the bacterium Moorella thermoacetica into being productive with light-absorbing gold nanoclusters. This results in a higher yield of chemical products and improved quantum efficiency compared to previous models.
New research shows promise with simulated nerve agents and potentially deadly toxins - the 'molecular baskets' can find and trap them for safe removal, paving the way for future medical applications.
Researchers have discovered that polymer nanoparticles exhibit distinct characteristics compared to larger particles of the same material, including surface mobility and elastic modulus. The findings could improve the performance of materials used in various applications, such as filter membranes and sound wave propagation.
Researchers developed a hybrid nanoplatform that locates tumors using three different types of contrast simultaneously, facilitating multimodal molecular medical imaging. The platform overcomes the limitations of single image modality while maximizing their advantages.
Researchers developed nanoparticles that bind to venom toxins, mitigating local damage and systemic distribution of toxins in mouse experiments. The treatment has the potential to be administered subcutaneously after a bite, offering a new approach to treating snakebites in rural settings.
Scientists at University of Toronto's Leslie Dan Faculty of Pharmacy have developed a combination approach using nanoparticles to improve chemotherapy response and boost anti-tumor immunity in breast cancer. The treatment resulted in a 60% cure rate and enhanced life expectancy by five-fold compared to treating with chemotherapy alone.
A new study from George Washington University Cancer Center found that nanoparticle-encapsulated doxorubicin is promising in treating triple-negative breast cancer. The smallest nanoparticles with slowest release of medication showed increased cell kill in resistant cancer cells, offering potential strategies to overcome drug resistance.
A team of researchers has created a breakthrough in 3D bioprinting by integrating oxygen-sensitive nanoparticles into gel materials, enabling real-time monitoring of metabolic activity and microenvironment of cells within living structures.
A new screening process, called Fast Indication of Nanoparticle Discovery (FIND), allows researchers to identify nanoparticles suitable for delivering therapeutic RNA into living cells. The technique inserts unique DNA snippets and a red-glowing Cre protein to verify nanoparticle entry into specific organs and cells.
Researchers at the University of South Australia have developed nanoparticles from green mango peel that can break down toxins in oil sludge through chemical oxidation. These plant-based nanoparticles successfully decontaminate oil-polluted soil, providing a novel and effective treatment for oil-contaminated soils.
Researchers have developed a novel method to assess the quality of iron oxide samples, enabling them to understand their effects on patient safety. By combining gamma ray spectroscopy with 'center of gravity' analysis, scientists can quantify diffusive oxidation processes and track changes over time.
Researchers at Brown University have successfully assembled complex macroscale superstructures from pyramid-shaped nanoparticle building blocks. The 3D supercrystals demonstrated in the study possess aligned atomic structures, which may lead to interesting optical properties.
Researchers developed Pd@NiO-x nanoparticles with unique core@shell interface structure, achieving high activity, selectivity and stability for direct H2O2 synthesis. The creation of porous NiO shell exposes Pd active sites, enhancing productivity and selectivity.
Engineers at Washington University in St. Louis have discovered the activation energy and kinetic factors of calcium carbonate's nucleation, key to predicting and controlling the process. This research can help create nanomaterials, control nanoparticle properties, and aid in designing larger-scale engineering processes.
Researchers have discovered a new use for green tea's EGCG: delivering therapeutic siRNAs into cells. This breakthrough could lead to treatments for diseases caused by gene misexpression.
Research found that silver nanoparticles and soluble silver cause inflammation in zebrafish gills, with nanoparticles leading to longer-term effects. After exposure, fish recovered from the metal, but continued to exhibit altered gene expression levels.
Researchers have developed a more efficient method for laying down thin-film circuitry using copper nanoparticle ink with green laser light. The study found that optimal settings for laser power and scanning speed can enhance conductivity, while sintering reduces film thickness by up to 74%.
Researchers at Argonne National Laboratory developed nanoparticle coatings that increase the sensitivity of photodetectors to UV radiation, enabling the detection of rare events and potential insights into neutrino oscillations. These enhanced detectors could also be used to enhance visible light in dim environments.
Scientists at ITMO University have developed a new material using silicon nanoparticles to improve perovskite solar cells' efficiency. The nanoparticles trap light of various wavelengths near the cell's active layer, maintaining stability and increasing absorption. This breakthrough could lead to more efficient and stable solar cells.
Osaka University-led researchers developed non-toxic nanoparticles that emit vivid, clean colors with high energy efficiency. The new particles use a chaotic material shell to achieve pure colors without rigid structures.
Researchers have developed a new nanoparticle that can target kidney cells and deliver medication directly to the site of the disease, potentially reducing side effects. This innovation may prove critical in addressing chronic kidney disease, which affects one in three Americans.
Researchers found that nanoparticles and contaminants can be deadly to human cells, especially when combined. Exposure to silver nanoparticles alone was less toxic, but combining them with cadmium ions increased cell death by 60%. The study highlights the need for regulations on nanoparticle releases into the environment.
Researchers have developed a drug-free method for detecting and destroying the bacteria that cause dental plaque. The approach uses nanoparticles made of hafnium oxide to target and kill harmful bacteria, reducing biofilm burden and preventing conditions like cavities and cardiovascular disease.
Researchers found significant quantities of TiO2 in beach waters off France, with concentrations ranging from 15-45 μg/L. The tiny nanoparticles can lose their protective coating under UV light or seawater composition, exposing toxic titanium dioxide to aquatic organisms.
Rice University scientists have created a magnetic nanoparticle compound that efficiently separates crude oil droplets from produced water. The nanoparticles are attracted to the magnet and bind to the oil, allowing for easy separation. This solution could be valuable for industry and offshore oil rigs.
Researchers have developed nanoparticles that can be excited with ultralow-power laser light, emitting visible light for deep-tissue imaging. The findings hold promise for advanced imaging systems to pinpoint single cancer cells, guiding high-precision surgeries and radiation treatments.