Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers found that low-dose radiation increases the uptake of therapeutic nanoparticles by glioblastomas, allowing for targeted siRNA delivery and improved survival in mouse models. The therapy also activates the immune response at the tumor site, decreasing PD-L1 expression and increasing CD8 T cell recruitment.
Theoretical approach uses layers formed by liquids to arrange nanoparticles into unique structures for optics, plasmonics and electronics applications. By controlling nanoparticle properties, researchers can create exotic arrangements, such as strings or sheets, with potential benefits in multi-stage chemical catalysis.
Researchers at North Carolina State University have developed a material that can change its color by manipulating the orientation of nanostructured columns in response to a magnetic field, mimicking the flashing colors of neon tetras.
Researchers found that magnetic stir bars become permanently contaminated with metal nanoparticles after a week of use, affecting subsequent reactions. Regular cleaning procedures are insufficient to remove such contamination completely.
Researchers have developed a novel method for detecting amphetamine and ketamine in latent fingermarks using nanocarrier-based biological fluorescent probes. The method allows for simultaneous detection of multiple drugs in a single fingerprint, providing a potential solution to combat drug abuse.
A new nanoparticle vaccine candidate has been designed to elicit potent neutralizing antibodies against respiratory syncytial virus (RSV), a leading cause of infant mortality worldwide. The vaccine's computer-designed nanoparticle platform holds promise for applying to other diseases, including flu and HIV.
Researchers created metallocorrole/protein nanoparticles that can both survive longer in the body and better snipe disease targets. The theranostics have huge chemotherapeutic potential, potentially shortening treatment duration and diminishing side effects for cancer patients.
Researchers have demonstrated a new way to perform functions essential to future computation at speeds trillions of times faster than current commercial devices. The team created a nanoscale spintronic semiconductor device that can partially switch between specific magnetic states in under a picosecond.
Tevis Jacobs will study individual nanoparticles using electron microscopy to understand atomic-scale relationships between adhesion and coarsening. The award enables the development of new methods for measuring nanoparticle attachment and stability on surfaces.
Researchers at UMass Medical School have developed a technology that allows mammals to see infrared light using nanoantennae injections. The temporary vision enhancement enables animals to perceive near-infrared patterns and shapes without interfering with their visible light ability.
Scientists have developed a nanotechnology that enables mice to see infrared light, opening the door for potential applications in civilian encryption, security, and military operations. The technology involves injecting nanoparticles into the mouse's eyes, which capture infrared wavelengths and emit shorter visible light wavelengths.
Researchers at Northwestern University have developed a new blueprint to understand and predict the properties of complex nanoparticles. The study enables the synthesis of polyelemental nanoparticles with up to seven different elements, providing a vast playground for exploring novel catalysts and light-emitting nanostructures.
Scientists from EPFL used directed evolution to modify DNA-wrapped single-walled carbon nanotubes, creating nanoparticles that emit stronger optical signals. After only two cycles of evolution, they achieved a 56% increase in signal strength.
A new genetic tool has been developed by MIT researchers, allowing for easier engineering of plants that can survive drought or resist fungal infections. The technique uses nanoparticles to deliver genes into the chloroplasts of plant cells, which have the potential to revolutionize plant biology and agriculture.
Researchers developed a nanoparticle-lipid bilayer hybrid-based computing platform that enables parallel computation using nanoparticles. The system consists of mobile Nano-Floaters and immobile Nano-Receptors, which can perform AND, OR, and INHIBIT logic operations, and are modularly wired to form complex logic circuits.
Russian researchers created star-shaped nanoparticles with sharp spikes using laser irradiation for intracellular delivery. The method achieved efficiency rates of over 95% and minimal toxicity, making it a potential alternative to existing technologies.
A Northwestern University team has developed a direct route to optimize spherical nucleic acids (SNAs) using a library approach and machine learning. This new method reveals the importance of structural variables in SNA efficacy, enabling researchers to design more effective cancer treatments.
Researchers developed three techniques for laser colorization on metal, creating optical effects that change the color of the treated surface. The techniques can be used to produce colorful artwork on metals with high reproducibility and potential for mass production.
Researchers developed peptide-coated platinum nanoparticles that selectively target and kill liver cancer cells. The nanoparticles are oxidized inside the cell, triggering a cytotoxic effect, while sparing healthy tissue.
Magnetic nanoparticles break down within stem cells, releasing iron that's stored in non-magnetic form or used to create new magnetic particles. This phenomenon may help explain the presence of natural magnetism in human cells.
Researchers have developed a new nano-painkiller that bypasses the blood-brain barrier and has been shown to be effective in treating intense pain without severe side effects. The new approach uses Leu-enkephalin-based nanoparticles that target peripherally located opioid receptors with lower abuse potential than morphine.
Researchers at the University of Manchester have developed a new technique to map elemental distributions in metal nanoparticles, potentially leading to more efficient catalysts for energy converting systems. The breakthrough uses spectroscopic single particle reconstruction to reveal atomic-scale chemistry in metal nanoparticles.
Researchers at the University of Connecticut created a sensor using iron oxide nanoparticles in silicone that can detect pressure, temperature, and vibration, as well as magnetic fields and sound waves. The sensor could potentially help burn victims feel again and serve as an early warning for workers exposed to high magnetic fields.
Researchers from Ural Federal University and University of Edinburgh have developed a new theory on the collective behavior of magnetic nanoparticles for cancer treatment. Their computer simulations show that particles interact and influence each other, producing a unique effect that is not described by traditional Debye theory.
A Vanderbilt University team developed a nanoparticle to target tumor-infiltrating immune cells and activate the STING pathway, a natural mechanism to mount an immune response against cancer. The breakthrough offers hope for patients who don't respond to checkpoint blockade therapies.
Scientists have identified natural antibodies within protein corona that trigger immune system response to nanoparticles. Depleting these antibodies reduces complement system activation, enabling safe delivery of cancer-fighting drugs and imaging agents.
Researchers developed a new catalyst composed of platinum and nickel, which is more efficient than pure platinum. The study used ultrabright x-rays to reveal the growth pathway and chemical characterization of the nanoparticles in real time.
Researchers found unexpected chemical compositions in 'magic nanoparticles' that display enhanced stability, including Fe6O4 and Ce3O12. The study also reveals oxygen-rich nanoparticles may explain carcinogenicity of oxide nanoparticles.
Researchers at Virginia Tech have developed a novel drug delivery system that uses attenuated bacteria cells to transport anti-cancer drugs directly to cancer sites, showing up to 100-fold improvements in distribution and retention. This innovative approach has the potential to revolutionize cancer treatment options.
This study introduces a green method for synthesizing benzopyrano and xanthenol compounds using TiO2 nanoparticles as catalysts. The reaction is carried out in aqueous medium at room temperature, yielding high yields (92-98%) within short reaction times.
A new study at Northwestern University has developed a revolutionary tool to rapidly test millions of nanoparticles for specific applications. The novel approach utilizes a combinatorial library, or megalibrary, of nanoparticles and an in situ Raman spectroscopy-based screening technique to identify optimal compositions.
Researchers developed a novel solid lipid nanoparticle (SLN) formulation using Vitamin E TPGS and glyceryl mono-oleate to enhance the delivery of vinorelbine bitartrate, improving its anticancer efficacy. The SLNs showed a biphasic release pattern and were 39.5 times more effective than the original drug.
Lipid nanoparticles have shown promise in delivering drugs to the brain due to their ability to cross biological barriers. By modifying their surface, these particles can effectively target brain cells and increase drug efficiency.
Researchers developed a new device to measure and control an optically trapped nanoparticle's motion with subatomic resolution. The device uses a light-guiding nanoscale device to monitor the particle's position with unprecedented sensitivity.
Researchers from NUST MISIS developed a new hybrid catalyst for carbon monoxide oxidation using hexagonal boron nitride and silver nanoparticles, achieving full conversion at 194 degrees Celsius. Increasing silver concentration may reduce the temperature further.
Researchers developed a novel method to adjust catalyst nanoparticle size during continuous flow, optimizing chemical reactions and reducing testing time. The technique improved the performance of metal-carrier catalysts, producing desired compounds with specific properties.
Researchers at Far Eastern Federal University found that arc welding produces toxic nanoparticles in the air, which can be inhaled through the respiratory system. The particles contain metal oxidation products, particularly those with diameters under 1 nanometer, and can translocate to the central nervous system.
A new Australian study has provided direct evidence that zinc oxide nanoparticles do not penetrate human skin or cause cellular toxicity after repeated application. The findings support the use of ZnO nanoparticle sunscreens, outweighing perceived risks and improving consumer confidence in these products.
A groundbreaking study found that billions of nanoplastics can accumulate in the bodies of marine organisms like great scallops within just six hours. The research, led by the University of Plymouth, showed that even smaller particles measuring 20nm had become dispersed throughout the body's organs.
Researchers at FAU have developed a new method for measuring the length and diameter distribution of plasmonic gold nanorods in one single experiment. The method combines multi-wavelength absorption optics and analytical ultracentrifugation, allowing for accurate analysis of nanoparticles in dispersions.
Researchers at City University of Hong Kong have developed a novel strategy to create high-strength alloys that are also extremely ductile and flexible. The breakthrough solution involves massive precipitation of nanoscale particles, solving the critical issue of the strength-ductility trade-off dilemma.
A team of McGill researchers has created a phosphorus-free anti-scaling solution based on hairy nanocellulose, providing an effective and environmentally friendly alternative to traditional methods. The breakthrough uses negatively charged carboxyl groups on cellulose nanoparticles to control scale formation.
Researchers from ITMO University developed a method to enhance enzyme activity using radio frequency radiation, resulting in acceleration of enzymatic processes. The technique uses magnetic nanoparticles to adsorb radio emission and convert it to heat, stabilizing the enzyme and allowing for remote control of biochemical systems.
A new study led by the University of Queensland and University of South Australia found that zinc oxide nanoparticles used in sunscreen do not penetrate the skin or cause cellular toxicity after repeated applications. The research refutes widespread claims about the safety of nanoparticulate-based sunscreens.
Researchers develop new method for selectively binding proteins to nanoparticles using co-assembling points of contact, promising applications in diagnostics and medicine. The method has potential for treating diseases such as Alzheimer's by dissolving amyloid aggregates.
Scientists at Nagoya Institute of Technology create raspberry-shaped nanoparticle that converts toxic carbon monoxide into harmless carbon dioxide. The unique surface nanostructure improves low-temperature CO oxidation activity and holds promise for future applications in catalysis.
A genetically programable strain of yeast fueled by light-harvesting nanoparticles can efficiently convert carbon into high-value chemicals. This new biohybrid system overcomes existing limitations in bioinorganic systems, offering a promising method for producing high-value chemicals.
Researchers at Rice University have developed a new technology that uses a moth-infecting virus and nanomagnets to deliver CRISPR/Cas9 payloads for gene editing. The therapy has the potential to treat genetic diseases such as sickle cell, muscular dystrophy, and cystic fibrosis.
Researchers developed stealth-cap technology to increase stability and biocompatibility of light-transducing nanoparticles. The new nanoparticles are water-soluble, stable in complex body fluids, and can store medications like cancer drugs.
Researchers at the University of Edinburgh developed a cost-effective method to create high-performance energy devices and diagnostic tests using nanoparticles. The electrospinning technique, which produces nanofibres with high surface area, has been successfully tested in fuel cell applications.
A new anti-thrombosis drug based on magnetite nanoparticles has been developed by ITMO University researchers. The drug successfully passed preclinical testing, showing a 20 times shorter clot dissolution time and a lower minimum dose required to achieve the therapeutic effect compared to traditional medications.
Researchers at Stanford University have developed a new technique to study individual nanoparticles undergoing photocatalytic reactions. The method, published in Nature Communications, uses a custom-designed specimen holder and mirrors to focus light onto the nanoparticle, allowing scientists to observe the reaction as it unfolds.
Researchers develop silver nanoparticles coated with anti-seizure drugs to kill brain-eating amoebae, increasing human cell survival rates. The drug-nanoparticle combos target protein receptors or ion channels on the amoeba's membrane, offering a potential treatment for deadly infections.
Drexel researchers have developed a polymer coating that helps nanoparticles evade the immune system and liver, allowing them to remain in circulation for longer periods. The mushroom-brush layer combination enables nanoparticles to reach cancerous tumors more effectively.
A team of researchers has discovered a noble metal-free catalyst system that is as active as platinum, thanks to the high entropy effect. The alloy, made up of five elements, forms new active centers that offer entirely new properties and are relevant for catalysis.
Zinc oxide nanoparticles exhibit antibacterial, anticancer, and antioxidant effects, but also induce toxic effects on various organs and systems. Their concentration-dependent toxicity highlights the importance of determining efficacy and safety.
Perovskite nanoparticles are capable of emitting different colors depending on the internal halogen element. Researchers at UNIST developed a simple method to replace certain elements via solution process, allowing for the creation of red, blue, and green LEDs with high luminous efficiency.
A joint research team has discovered a new analysis method that reveals nanoparticles continue to grow and transform into bulk materials in the early stages of nanomaterial growth. This finding contradicts classical nucleation theory, which assumes critical nuclei are created early in material growth.
New research shows promise with simulated nerve agents and potentially deadly toxins - the 'molecular baskets' can find and trap them for safe removal, paving the way for future medical applications.
Researchers have created a more efficient path to producing solar fuels by enticing the bacterium Moorella thermoacetica into being productive with light-absorbing gold nanoclusters. This results in a higher yield of chemical products and improved quantum efficiency compared to previous models.