Articles tagged with Nanoparticles
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Scientists at University of Toronto's Leslie Dan Faculty of Pharmacy have developed a combination approach using nanoparticles to improve chemotherapy response and boost anti-tumor immunity in breast cancer. The treatment resulted in a 60% cure rate and enhanced life expectancy by five-fold compared to treating with chemotherapy alone.
A new screening process, called Fast Indication of Nanoparticle Discovery (FIND), allows researchers to identify nanoparticles suitable for delivering therapeutic RNA into living cells. The technique inserts unique DNA snippets and a red-glowing Cre protein to verify nanoparticle entry into specific organs and cells.
A new study from George Washington University Cancer Center found that nanoparticle-encapsulated doxorubicin is promising in treating triple-negative breast cancer. The smallest nanoparticles with slowest release of medication showed increased cell kill in resistant cancer cells, offering potential strategies to overcome drug resistance.
A team of researchers has created a breakthrough in 3D bioprinting by integrating oxygen-sensitive nanoparticles into gel materials, enabling real-time monitoring of metabolic activity and microenvironment of cells within living structures.
Researchers at the University of South Australia have developed nanoparticles from green mango peel that can break down toxins in oil sludge through chemical oxidation. These plant-based nanoparticles successfully decontaminate oil-polluted soil, providing a novel and effective treatment for oil-contaminated soils.
Researchers have developed a novel method to assess the quality of iron oxide samples, enabling them to understand their effects on patient safety. By combining gamma ray spectroscopy with 'center of gravity' analysis, scientists can quantify diffusive oxidation processes and track changes over time.
Engineers at Washington University in St. Louis have discovered the activation energy and kinetic factors of calcium carbonate's nucleation, key to predicting and controlling the process. This research can help create nanomaterials, control nanoparticle properties, and aid in designing larger-scale engineering processes.
Researchers have discovered a new use for green tea's EGCG: delivering therapeutic siRNAs into cells. This breakthrough could lead to treatments for diseases caused by gene misexpression.
Researchers at Brown University have successfully assembled complex macroscale superstructures from pyramid-shaped nanoparticle building blocks. The 3D supercrystals demonstrated in the study possess aligned atomic structures, which may lead to interesting optical properties.
Researchers developed Pd@NiO-x nanoparticles with unique core@shell interface structure, achieving high activity, selectivity and stability for direct H2O2 synthesis. The creation of porous NiO shell exposes Pd active sites, enhancing productivity and selectivity.
Research found that silver nanoparticles and soluble silver cause inflammation in zebrafish gills, with nanoparticles leading to longer-term effects. After exposure, fish recovered from the metal, but continued to exhibit altered gene expression levels.
Researchers have developed a more efficient method for laying down thin-film circuitry using copper nanoparticle ink with green laser light. The study found that optimal settings for laser power and scanning speed can enhance conductivity, while sintering reduces film thickness by up to 74%.
Researchers at Argonne National Laboratory developed nanoparticle coatings that increase the sensitivity of photodetectors to UV radiation, enabling the detection of rare events and potential insights into neutrino oscillations. These enhanced detectors could also be used to enhance visible light in dim environments.
Scientists at ITMO University have developed a new material using silicon nanoparticles to improve perovskite solar cells' efficiency. The nanoparticles trap light of various wavelengths near the cell's active layer, maintaining stability and increasing absorption. This breakthrough could lead to more efficient and stable solar cells.
Osaka University-led researchers developed non-toxic nanoparticles that emit vivid, clean colors with high energy efficiency. The new particles use a chaotic material shell to achieve pure colors without rigid structures.
Researchers have developed a new nanoparticle that can target kidney cells and deliver medication directly to the site of the disease, potentially reducing side effects. This innovation may prove critical in addressing chronic kidney disease, which affects one in three Americans.
Researchers found that nanoparticles and contaminants can be deadly to human cells, especially when combined. Exposure to silver nanoparticles alone was less toxic, but combining them with cadmium ions increased cell death by 60%. The study highlights the need for regulations on nanoparticle releases into the environment.
Researchers found significant quantities of TiO2 in beach waters off France, with concentrations ranging from 15-45 μg/L. The tiny nanoparticles can lose their protective coating under UV light or seawater composition, exposing toxic titanium dioxide to aquatic organisms.
Researchers have developed a drug-free method for detecting and destroying the bacteria that cause dental plaque. The approach uses nanoparticles made of hafnium oxide to target and kill harmful bacteria, reducing biofilm burden and preventing conditions like cavities and cardiovascular disease.
Rice University scientists have created a magnetic nanoparticle compound that efficiently separates crude oil droplets from produced water. The nanoparticles are attracted to the magnet and bind to the oil, allowing for easy separation. This solution could be valuable for industry and offshore oil rigs.
Researchers have developed nanoparticles that can be excited with ultralow-power laser light, emitting visible light for deep-tissue imaging. The findings hold promise for advanced imaging systems to pinpoint single cancer cells, guiding high-precision surgeries and radiation treatments.
Researchers at Lawrence Berkeley National Laboratory have discovered a way to transform a liquid-like state into a solid-like state and back again by introducing a chemical compound. The study has implications for developing all-liquid electronics and interacting with cells, and could lead to new ways of controlling nanoscale elements.
Nanoparticles have been modified to be absorbed through the lymphatic system, increasing bioavailability seven-fold. The new technique uses glycocholic acid as a cloak to help nanoparticles slip incognito through the small intestine lining.
Researchers have successfully designed nanoparticles that can be absorbed through the intestine and into the bloodstream when taken orally. The modified particles showed improved uptake in rats, with about 47% making it into the blood, compared to 7% for unmodified particles.
Researchers have successfully imaged the surface structures of silver nanoparticles at atomic resolution using scanning tunnelling microscopy (STM). The technique allows for the identification of individual parts of molecules on the nanoparticle's surface, providing insights into their chemical properties and molecular interactions.
Researchers used FDA-approved nanoparticles to disrupt biofilms and prevent tooth decay in both human-plaque-like biofilm and animal models. The treatment showed strong evidence of its effectiveness in preventing mineral destruction of the tooth's surface and blocking cavity formation.
Researchers have developed a novel delivery system using magnetic nanoparticles to target chemotherapy drugs to spinal cord tumors, which are difficult to reach due to the blood-brain barrier. This approach shows promise in treating intramedullary spinal cord tumors with improved survival rates and reduced side effects.
A double-layered nanoparticle vaccine made with peptides has been found to effectively protect mice against the influenza A virus. The vaccine triggers immune responses of both B and T lymphocytes, providing broad cross-protection against a wide range of diverse influenza viruses.
Scientists from ITMO University discovered that the Great Pyramid can concentrate electromagnetic energy in its internal chambers and base. The research used numerical modeling and analytical methods to predict this phenomenon, which could lead to the development of nanoparticles for sensors and solar cells.
Researchers at Ruhr-University Bochum have created a new technique to study the chemical reactions of individual silver nanoparticles in real-time. They found that under certain conditions, these particles transform into poorly soluble silver chloride, which can be toxic for many organisms.
Researchers at the University of Illinois Chicago developed a magnetic surgical cement that can guide nanoparticles to lesions near spinal fractures, providing targeted drug delivery. The technology has the potential to become a surgical option for patients with primary spinal column tumors or metastasizing tumors.
The study found that different shapes and formulations of nucleic acid nanoparticles triggered specific responses from immune cells, with varying effects on cytokine production. The researchers discovered an 'auxiliary' system for managing immune response, using a molecular alphabet to communicate with the human immune system.
Ceria nanoparticles selectively remove reactive oxygen species from mitochondria, intracellular and extracellular spaces, improving Parkinson's disease symptoms in mice. Lowering oxidative stress in these compartments is crucial for treating the disease.
The US Department of Energy awards Rice University researchers $1.1 million to develop single-particle spectroscopy techniques and analyze mechanisms to improve nanoparticle-based electrocatalysts. The goal is to fine-tune nanoscale electrocatalysts for future applications in various industrial processes.
A KAIST team identified that the formation of metal-oxide interfaces has a synergistic catalytic effect on bimetal catalysts. This is achieved through in situ imaging, revealing that interfacial platinum-nickel oxide nanostructures increase catalytic activity while providing thermodynamically efficient reaction pathways.
A team of toxicologists led by FEFU researchers found that carbon nanotubes and silicon nanotubes exhibited acute toxic effects on Heterosigma akashiwo microalgae at concentrations as low as 100 mg/l. Silicon nanotubes were more toxic than carbon nanotubes due to their smaller size and hydrophilic properties.
Researchers at UMBC developed nanoparticles that increase blast trauma survival rates and reduce anxiety. The nanoparticles also protect the brain from damage by reducing signs of inflammatory cells and neural cell death.
A GW researcher studied the potential of combining nitric oxide-releasing nanoparticles with efinaconazole to improve onychomycosis treatment. The study found that this combo is more effective and has a lower cost than current treatments, opening doors for better regimens.
Engineers at the University of Houston are developing nanoparticles loaded with antibiotics to reduce dosages and prevent microbiome damage. The study, supported by the USDA National Institute of Food and Agriculture, aims to find alternative methods to combat antibiotic resistance.
Researchers at the University of Texas at Arlington have developed a new nanoparticle-based platform that can simultaneously image and treat esophageal cancer cells. The platform uses near-infrared fluorescence for better tissue imaging and tumor targeting properties, making it easier to detect and guide surgeons in removing tumors.
University of Tsukuba researchers developed a method to balance catalyst activity and stability in acidic liquids using graphene coatings. The approach resulted in nanoparticles with high durability and similar catalytic activity to expensive platinum-based catalysts.
Scientists at the University at Buffalo have developed heated magnetic nanoparticles that can selectively target and destroy tumors with significant amounts of heat under low-magnetic fields. The new technology has potential benefits over other treatments, including minimal side effects and deeper penetration into hard-to-reach body pa...
Researchers at Ural Federal University have discovered that controlling intrinsic defects in nanoparticles can enhance their energy conversion capabilities. This breakthrough could lead to improved solar cell efficiency by up to 50%.
A new study found that combining nanomaterials with nutrient runoff from fertilized cropland can intensify harmful algal blooms in wetlands. The nanoparticles accelerated the growth of algae, reducing dissolved oxygen levels and creating toxic conditions for aquatic organisms.
The new foam reacts to sound waves of high and low frequencies, cutting the level of noise transmission by 20-22 dB. The material is cheaper and easier to apply than aerogel, with improved acoustic characteristics obtained through additional impregnation with nanoparticles.
A Northwestern University team developed a novel nanolaser that changes colors by controlling the spacing among metal nanoparticles, inspired by chameleons' skin structure. The laser is robust, tunable, reversible and highly sensitive to strain.
Researchers have found a way to convert nanoparticle-coated microscopic beads into lasers smaller than red blood cells. These microlasers can constantly and stably emit light for hours at a time, even when submerged in biological fluids. The innovation opens up the possibility for imaging or controlling biological activity with infrare...
Researchers develop nanosystem that selectively targets cancerous tumors using gelonin protein toxin, cloaked in extracellular vesicles from tumor cells. The system releases toxic protein into cancer cell cytosol, killing the cell without harming healthy tissue.
Researchers have designed a coating infused with antimicrobial agents and mimicking the patterned diamond-like texture of shark skin. The coating effectively killed over 95% of E. coli and 80% of Staphylococcus aureus bacteria when exposed to UV light, making it a potential solution to combat hospital infections.
Researchers from the U.S. Army Research Laboratory and Texas Tech University demonstrated a 30-percent enhancement in TNT detonation velocity by adding novel aluminum nanoparticles. The AIH-coated nanoparticles showed improved reactivity due to their unique morphological feature, leading to enhanced explosive performance.
Silver nanoparticles have been found to be highly toxic to Danio fish embryos, with flat particles being more toxic than spherical ones. The research suggests that the toxicity of nanosilver is due to the presence of nanoparticles themselves, not just silver ions.
Researchers at Penn State have developed a new nanoparticle-based drug delivery system that targets cancer cells using mechanical properties of diseased cells. The 'mechanotargeting' approach outperforms existing 'chemotargeting' strategy in delivering drugs to targeted cells.
A novel separation technique using density gradient ultracentrifugation is introduced for colloidal nanostructures. The method demonstrates versatility in separating nanoparticles according to their unique properties.
Researchers at MIT have developed an AI-based method to design multilayered nanoparticles with desired properties, potentially speeding up the development of new materials. The technique uses computational neural networks to learn how a nanoparticle's structure affects its behavior, allowing for faster prediction and design.
Sheereen Majd aims to improve nanoparticle drug delivery by targeting diseased cells and minimizing off-targeting. Her research combines existing technologies to create a precise and stable carrier system, promising efficient delivery of bioactive molecules to specific sites in the body.
Researchers developed nanoparticles carrying temozolomide and a bromodomain inhibitor to target glioblastoma tumors. The particles, coated with transferrin, successfully delivered large doses of chemotherapy drugs directly to the tumor site, reducing side effects.
The ETH Zurich researchers developed nanovalves that can control individual nanoparticles in liquids using electric forces. This technology enables sorting and manipulation of tiny particles such as metal, semiconductor, virus, liposomes, and antibodies.
A new method for studying semiconductor nanoparticles has been developed using the magneto-optic effect, allowing for non-invasive analysis without altering the structure. The method was successfully tested on cadmium telluride nanoparticles and showed promising results.
A team of chemists at Penn State developed a designer's toolkit to construct complex nanoparticles using a simple mix-and-match process. They created a library of 47 distinct nanoparticles with varying materials and shapes, overcoming the bottleneck in laboratory synthesis.
A Brazilian research team has developed a novel technique to produce high-performance silver nanoparticles with 32 times the bactericidal capacity of existing materials. The new method uses pulsed laser irradiation and reduces production costs, making it economically feasible for large-scale applications.