Articles tagged with Nanoparticles
Researchers have successfully designed nanoparticles that can be absorbed through the intestine and into the bloodstream when taken orally. The modified particles showed improved uptake in rats, with about 47% making it into the blood, compared to 7% for unmodified particles.
Researchers at Lawrence Berkeley National Laboratory have discovered a way to transform a liquid-like state into a solid-like state and back again by introducing a chemical compound. The study has implications for developing all-liquid electronics and interacting with cells, and could lead to new ways of controlling nanoscale elements.
Nanoparticles have been modified to be absorbed through the lymphatic system, increasing bioavailability seven-fold. The new technique uses glycocholic acid as a cloak to help nanoparticles slip incognito through the small intestine lining.
Researchers have successfully imaged the surface structures of silver nanoparticles at atomic resolution using scanning tunnelling microscopy (STM). The technique allows for the identification of individual parts of molecules on the nanoparticle's surface, providing insights into their chemical properties and molecular interactions.
Researchers used FDA-approved nanoparticles to disrupt biofilms and prevent tooth decay in both human-plaque-like biofilm and animal models. The treatment showed strong evidence of its effectiveness in preventing mineral destruction of the tooth's surface and blocking cavity formation.
Researchers at Ruhr-University Bochum have created a new technique to study the chemical reactions of individual silver nanoparticles in real-time. They found that under certain conditions, these particles transform into poorly soluble silver chloride, which can be toxic for many organisms.
Researchers have developed a novel delivery system using magnetic nanoparticles to target chemotherapy drugs to spinal cord tumors, which are difficult to reach due to the blood-brain barrier. This approach shows promise in treating intramedullary spinal cord tumors with improved survival rates and reduced side effects.
A double-layered nanoparticle vaccine made with peptides has been found to effectively protect mice against the influenza A virus. The vaccine triggers immune responses of both B and T lymphocytes, providing broad cross-protection against a wide range of diverse influenza viruses.
Scientists from ITMO University discovered that the Great Pyramid can concentrate electromagnetic energy in its internal chambers and base. The research used numerical modeling and analytical methods to predict this phenomenon, which could lead to the development of nanoparticles for sensors and solar cells.
Researchers at the University of Illinois Chicago developed a magnetic surgical cement that can guide nanoparticles to lesions near spinal fractures, providing targeted drug delivery. The technology has the potential to become a surgical option for patients with primary spinal column tumors or metastasizing tumors.
The study found that different shapes and formulations of nucleic acid nanoparticles triggered specific responses from immune cells, with varying effects on cytokine production. The researchers discovered an 'auxiliary' system for managing immune response, using a molecular alphabet to communicate with the human immune system.
Ceria nanoparticles selectively remove reactive oxygen species from mitochondria, intracellular and extracellular spaces, improving Parkinson's disease symptoms in mice. Lowering oxidative stress in these compartments is crucial for treating the disease.
The US Department of Energy awards Rice University researchers $1.1 million to develop single-particle spectroscopy techniques and analyze mechanisms to improve nanoparticle-based electrocatalysts. The goal is to fine-tune nanoscale electrocatalysts for future applications in various industrial processes.
A KAIST team identified that the formation of metal-oxide interfaces has a synergistic catalytic effect on bimetal catalysts. This is achieved through in situ imaging, revealing that interfacial platinum-nickel oxide nanostructures increase catalytic activity while providing thermodynamically efficient reaction pathways.
A team of toxicologists led by FEFU researchers found that carbon nanotubes and silicon nanotubes exhibited acute toxic effects on Heterosigma akashiwo microalgae at concentrations as low as 100 mg/l. Silicon nanotubes were more toxic than carbon nanotubes due to their smaller size and hydrophilic properties.
Researchers at UMBC developed nanoparticles that increase blast trauma survival rates and reduce anxiety. The nanoparticles also protect the brain from damage by reducing signs of inflammatory cells and neural cell death.
A GW researcher studied the potential of combining nitric oxide-releasing nanoparticles with efinaconazole to improve onychomycosis treatment. The study found that this combo is more effective and has a lower cost than current treatments, opening doors for better regimens.
Engineers at the University of Houston are developing nanoparticles loaded with antibiotics to reduce dosages and prevent microbiome damage. The study, supported by the USDA National Institute of Food and Agriculture, aims to find alternative methods to combat antibiotic resistance.
Researchers at the University of Texas at Arlington have developed a new nanoparticle-based platform that can simultaneously image and treat esophageal cancer cells. The platform uses near-infrared fluorescence for better tissue imaging and tumor targeting properties, making it easier to detect and guide surgeons in removing tumors.
University of Tsukuba researchers developed a method to balance catalyst activity and stability in acidic liquids using graphene coatings. The approach resulted in nanoparticles with high durability and similar catalytic activity to expensive platinum-based catalysts.
Scientists at the University at Buffalo have developed heated magnetic nanoparticles that can selectively target and destroy tumors with significant amounts of heat under low-magnetic fields. The new technology has potential benefits over other treatments, including minimal side effects and deeper penetration into hard-to-reach body pa...
Researchers at Ural Federal University have discovered that controlling intrinsic defects in nanoparticles can enhance their energy conversion capabilities. This breakthrough could lead to improved solar cell efficiency by up to 50%.
A new study found that combining nanomaterials with nutrient runoff from fertilized cropland can intensify harmful algal blooms in wetlands. The nanoparticles accelerated the growth of algae, reducing dissolved oxygen levels and creating toxic conditions for aquatic organisms.
The new foam reacts to sound waves of high and low frequencies, cutting the level of noise transmission by 20-22 dB. The material is cheaper and easier to apply than aerogel, with improved acoustic characteristics obtained through additional impregnation with nanoparticles.
A Northwestern University team developed a novel nanolaser that changes colors by controlling the spacing among metal nanoparticles, inspired by chameleons' skin structure. The laser is robust, tunable, reversible and highly sensitive to strain.
Researchers have found a way to convert nanoparticle-coated microscopic beads into lasers smaller than red blood cells. These microlasers can constantly and stably emit light for hours at a time, even when submerged in biological fluids. The innovation opens up the possibility for imaging or controlling biological activity with infrare...
Researchers develop nanosystem that selectively targets cancerous tumors using gelonin protein toxin, cloaked in extracellular vesicles from tumor cells. The system releases toxic protein into cancer cell cytosol, killing the cell without harming healthy tissue.
Researchers have designed a coating infused with antimicrobial agents and mimicking the patterned diamond-like texture of shark skin. The coating effectively killed over 95% of E. coli and 80% of Staphylococcus aureus bacteria when exposed to UV light, making it a potential solution to combat hospital infections.
Researchers from the U.S. Army Research Laboratory and Texas Tech University demonstrated a 30-percent enhancement in TNT detonation velocity by adding novel aluminum nanoparticles. The AIH-coated nanoparticles showed improved reactivity due to their unique morphological feature, leading to enhanced explosive performance.
Silver nanoparticles have been found to be highly toxic to Danio fish embryos, with flat particles being more toxic than spherical ones. The research suggests that the toxicity of nanosilver is due to the presence of nanoparticles themselves, not just silver ions.
Researchers at Penn State have developed a new nanoparticle-based drug delivery system that targets cancer cells using mechanical properties of diseased cells. The 'mechanotargeting' approach outperforms existing 'chemotargeting' strategy in delivering drugs to targeted cells.
A novel separation technique using density gradient ultracentrifugation is introduced for colloidal nanostructures. The method demonstrates versatility in separating nanoparticles according to their unique properties.
Researchers at MIT have developed an AI-based method to design multilayered nanoparticles with desired properties, potentially speeding up the development of new materials. The technique uses computational neural networks to learn how a nanoparticle's structure affects its behavior, allowing for faster prediction and design.
Sheereen Majd aims to improve nanoparticle drug delivery by targeting diseased cells and minimizing off-targeting. Her research combines existing technologies to create a precise and stable carrier system, promising efficient delivery of bioactive molecules to specific sites in the body.
Researchers developed nanoparticles carrying temozolomide and a bromodomain inhibitor to target glioblastoma tumors. The particles, coated with transferrin, successfully delivered large doses of chemotherapy drugs directly to the tumor site, reducing side effects.
The ETH Zurich researchers developed nanovalves that can control individual nanoparticles in liquids using electric forces. This technology enables sorting and manipulation of tiny particles such as metal, semiconductor, virus, liposomes, and antibodies.
A new method for studying semiconductor nanoparticles has been developed using the magneto-optic effect, allowing for non-invasive analysis without altering the structure. The method was successfully tested on cadmium telluride nanoparticles and showed promising results.
A team of chemists at Penn State developed a designer's toolkit to construct complex nanoparticles using a simple mix-and-match process. They created a library of 47 distinct nanoparticles with varying materials and shapes, overcoming the bottleneck in laboratory synthesis.
A Brazilian research team has developed a novel technique to produce high-performance silver nanoparticles with 32 times the bactericidal capacity of existing materials. The new method uses pulsed laser irradiation and reduces production costs, making it economically feasible for large-scale applications.
Researchers investigated the interaction between induced membrane vesicles and target cells, finding that proteinase K treatment inhibits internalization. The study suggests that artificial microvesicles can be designed to specifically deliver anti-tumor drugs to cancer cells.
Researchers discovered that 2D cadmium telluride sheets can spontaneously fold into nanoscrolls when attached with specific organic molecules. This effect may be used in the development of new devices, including optic materials and light-emitting matrices.
Researchers have created nanoparticles that can convert near-infrared light into visible light, potentially increasing the efficiency of solar cells. The particles are coated with organic dyes that act as antennas to gather and reemit light, raising the possibility of capturing a broader spectrum of sunlight.
Researchers have developed biomarkers to detect harmful environmental contaminants in wildlife, enabling faster development of diagnostic tools. Additionally, scientists have created a more sustainable method for producing biodiesel from low-cost cooking oil waste using nanoparticles.
The study found that the magnetic field orientation of magnetosomes is slightly tilted, deviating from the chain direction. This tilt may explain the helical shape of magnetosome chains, a crucial aspect of magnetotactic bacteria's internal compass construction.
Dr. Christian Marín-Muller developed a microRNA treatment for pancreatic cancer and founded Speratum CR, a biotech company with the goal of creating effective therapies. The company has successfully completed preclinical studies and is planning to initiate its first human trial.
Researchers at Texas A&M University have discovered a new class of clay nanoparticles that can direct human stem cells to become bone or cartilage cells. These nanoparticles, similar to flaxseed in shape, can grow tissue from stem cells in the absence of growth factors.
Researchers developed nanoparticles that deliver microRNA-29b to lung tumors, potentially improving treatment outcomes. The technology overcomes limitations of traditional delivery methods and demonstrates promising results in mouse models.
Researchers have developed a tool using carbon nanoparticles to detect antidepressants in urine samples, improving analytical properties and enabling early disease diagnosis. The new method enhances the ability to adsorb, making it fast and easy to extract antidepressants from urine, even at low concentrations.
A KAIST team created a technology to print heat patterns on a micron scale for controlling biological activities remotely. They achieved this by integrating precision inkjet printing with bio-functional thermo-plasmonic nanoparticles.
Researchers at KAUST have developed a printable magnetic substrate that can be used to produce radio frequency devices with adjustable capacity and frequency tuning. The innovative technology uses iron-based nanoparticles in an ink-like substance to create antennas with improved performance and lower costs.
Scientists have developed a method to combine up to eight different metals in a single nanoparticle, creating stable alloys with useful applications in the chemical and energy industries. The new technique uses shock waves to heat and cool the metals, producing homogeneous nanoparticles with broad catalytic properties.
Research shows that nanoparticles can cause DNA damage to developing brain cells when exposed to cellular barriers. This damage is dependent on astrocytes and has implications for the development of potential drug targets in treating neurodegenerative conditions.
Dr. Juhyun Lee is using a $154,000 grant from the American Heart Association to develop a microscope that can capture 3-D motion and track gene development in zebrafish. This research could lead to identifying heart abnormalities and diagnosing congenital conditions for potential treatment with gene therapy.
Scientists at the University of Maryland have created nanoparticles composed of up to eight distinct elements, greatly expanding the landscape of nanomaterials. This breakthrough enables a wide range of applications in catalysis, energy storage, and bio/plasmonic imaging.
Researchers develop a heat-shock process to form high entropy alloyed nanoparticles from multiple elements. The resulting nanoparticles exhibit homogeneous crystal structures and potential applications as catalysts in emerging energy technologies.
Researchers have developed opto-thermoelectric nanotweezers that can control particles at the nanoscale and analyze them in-situ. This technology has the potential to lead to new discoveries in nanotechnology, individual health monitoring, and biological systems.
Researchers at DESY's NanoLab found that nanoparticles with a large number of edges are more efficient in catalytic reactions. The study revealed that the different facets of the nanoparticles become inactive due to growing oxide islands, leaving active sites for the reaction.
Researchers at NYU Tandon School of Engineering have made a discovery that can flag the barest presence of viruses or proteins, as well as detect airborne chemical warfare agents. The breakthrough enables biosensors tailored to specific applications, from wearable sensors for soldiers to nanoparticle drug uptake.
Researchers have developed low-cost, low-tech solutions to improve water quality in municipal tanks by circulating water through shower head-like attachments. Additionally, they've found effective adsorbents using polymer-coated magnetic nanoparticles to remove micropollutants from water, which can be reused and restored.
Researchers at BWH discovered that cell sex influences nanoparticle uptake, response to reprogramming techniques, and paracrine factors. These findings may help develop sex-specific nanomedicines for targeted drug delivery applications.