Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers at MIT have created a new delivery system for the CRISPR genome-editing system, using nanoparticles to target and delete disease-causing genes. The technique achieved an 80% success rate in deleting the Pcsk9 gene, which regulates cholesterol levels, resulting in a 35% drop in total cholesterol levels.
Researchers developed a bone-targeted nanoparticle that delivers chemotherapy directly to bone lesions, reducing tumor size and pain. The targeted nanoparticles showed a strong burst release of cabazitaxel and increased binding to bone compared to non-targeted nanoparticles.
Self-reporting theranostic nanoparticles can provide real-time disease monitoring and tracking. The emerging field of responsive theranostic nanoparticles has the potential to advance imaging platforms and improve disease diagnosis.
Scientists at the University of Michigan found that injecting nanoparticles can redirect neutrophil immune cells away from an injury site, reducing inflammation. This discovery could lead to new treatments for acute lung injuries, sepsis, and atherosclerosis.
Researchers at KAUST developed a solvent-free synthesis method for metal-sulfide nanoparticles using thiourea. The new method produces controllable composition and size of nanoparticles, with potential applications in electrical, optical, and chemical devices.
A new study finds that a 70-year-old malaria drug can block immune cells in the liver, allowing nanoparticles to reach cancer cells. The research showed improved drug delivery to breast tumors and accumulation in mouse tumors and lungs.
Researchers developed a way to control polymer molecule shape, leading to non-spherical nanoparticles that can encapsulate drugs. These natural-shaped plastic nanoparticles have shown preliminary evidence of entering tumor cells more easily than spherical ones.
Researchers from Kumamoto University developed a method to activate silver nanoparticle antibacterial properties at will. Pulsed laser irradiation transformed the shape of gold-coated silver nanoparticles, increasing their antibacterial activity against E. coli.
Researchers developed a new method to create novel nanoporous materials with unique optical, magnetic, electronic and catalytic properties. The technique allows for the creation of tunable nanoporous materials with varying pore sizes by changing the composition of nanoparticles and liquids.
The study confirms Einstein's theoretical analysis of Brownian motion by observing the Kramers turnover in levitated nanoparticles. The researchers found that the transition rate between states depends on friction and grows with decreasing friction before decreasing again at low friction levels.
A team of scientists from UC Santa Barbara tested the effect of sulfurized nano-zero-valent iron on a common freshwater alga and found that it picked up cadmium and alleviated toxicity. Organic material produced by the algae mitigated the nanoparticle's toxicity, allowing for greater remediation.
Scientists at Chalmers University of Technology have created a new method to map individual nanoparticles, allowing for improved nanomaterials and safer technologies. The discovery paves the way for the development of more efficient hydrogen detectors and other applications.
Scientists have developed intelligent nanoparticles that can heat cancer cells to a high temperature, but then self-regulate and lose heat before causing harm to healthy tissue. This breakthrough could lead to a more effective treatment method for cancer patients.
Researchers from Lomonosov Moscow State University developed a new technique to detect volatile compounds, including chlorine, using metallic nanoparticles. The method combines optical detection with dynamic gas extraction and shows high sensitivity without sample preparation.
Researchers successfully deliver platinum-based chemotherapy drugs via nanoparticles to treat nonmuscle-invasive bladder cancer, reducing systemic absorption and toxicity. The study offers a potential less toxic clinical alternative to standard chemotherapy.
This study investigates the early stages of antibacterial damage caused by Silver and Copper-based nanoparticles on Gram-negative Pseudomonas aeruginosa. TEM and STEM-HAADF techniques reveal changes in bacterial structure, including adhesion, penetration, and damage to cellular components.
Scientists at ETH Zurich have developed a method to monitor lipolysis in real-time by analyzing exhaled acetone during exercise. The new breath test can detect when the body starts burning fat, allowing athletes to optimize their training regimen.
Researchers developed combined photoacoustic imaging and photothermal therapy using Bilirubin (BR) nanoparticles, showing high biocompatibility and outstanding therapeutic effects. The technology has the potential to improve cancer diagnosis and treatment outcomes.
Researchers at Berkeley Lab have created a new two-dimensional film that can direct non-mixing liquids into exotic architectures, offering potential for soft robotics, liquid circuitry and energy conversion. The 'bijel' substance is made of polymers and nanoparticles and has been simplified to be easier to produce.
Researchers at HRL Laboratories successfully 3D print high-strength aluminum alloys, including Al7075 and Al6061, overcoming a long-standing challenge in additive manufacturing. Their nanoparticle functionalization technique prevents hot cracking and retains alloy strength.
A team of scientists has developed a new method for producing non-iridescent, bright structural colors inspired by the iridescence of bird feathers. The process uses a simple one-pot reverse emulsion technique to create supraballs with high color saturation and brightness.
A new medicated skin patch has been developed that can transform white fat into brown fat locally, increasing metabolism and reducing fat. The patch was tested in obese mice with significant results, including a 20% reduction in treated side fat and lower fasting blood glucose levels.
Researchers have developed multifunctional nano-sized drug carriers based on reactive polypept(o)ides, which can be manipulated to control their morphology and function. These carriers exhibit stable circulation behavior and show promise for immunotherapy of malignant melanoma.
A team of researchers has developed a simplified approach to directly converting methane to methanol, reducing the need for high heat and pressure. The discovery utilizes colloidal gold-palladium nanoparticles in aqueous solution under mild conditions, enabling the selective oxidation of methane to methanol.
Okinawa Institute of Science and Technology (OIST) scientists have designed a novel silicon-based anode to provide lithium batteries with increased power and better stability. The new anode, featuring nanostructured layers of silicon, improves the battery's ability to charge and deliver energy over time.
A biodegradable nanoparticle injection after a spinal cord injury prevents inflammation and scarring that inhibits repair. Mice with the treatment were able to walk better than those without, suggesting a potential new approach for human spinal cord injury treatment.
Researchers eliminate almost all nanoparticle emissions from some 3-D printers using a new approach that involves enclosing the device with a HEPA filter and printing at low temperatures.
Researchers at Fred Hutchinson Cancer Center developed a nanoparticle delivery system to extend the therapeutic potential of messenger RNA, delivering gene changes to targeted cells. The 'hit-and-run' genetic programming approach can be easily scaled up for various disease applications.
Researchers have developed a method that targets cancerous tumors with chemotherapy, delivering the drug directly to cancer cells while protecting healthy cells. The treatment uses nanoparticles and ultrasound to improve delivery, showing promising results in mice experiments.
Researchers at ITMO University have developed a new approach for printing luminescent structures using europium-doped zirconia nanoparticle ink. The ink enables the fabrication of custom holograms with high stability and durability.
Scientists have created magnetic nanobiocomposite beads that can effectively remove oxybenzone, a coral killer found in sunblock, from seawater. The beads, made from environmentally friendly materials, can capture high concentrations of oxybenzone and have shown promising results in laboratory tests.
Researchers have successfully formed and imaged tiny quasicrystals using silica nanoparticles, revealing a non-periodic yet ordered structure. The team used transmission electron microscopy to capture the growth process, which was influenced by varying concentrations of chemical compounds and mechanical stirring.
Researchers developed a minimally invasive technique using magnetism to activate specific cells in the brain, inducing bodily movements such as running and rotating. This breakthrough could lead to advances in studying and treating neurological diseases, including traumatic brain injuries, Parkinson's disease, and depression.
Research at RIT develops new precision quantum sensing solutions using levitated optomechanics, capturing data with improved accuracy. The study aims to create smaller and lighter sensors for various applications, including detecting gravitational waves and perfecting quantum computing.
Environmental scientists at Virginia Tech have discovered that burning coal produces tiny titanium oxide nanoparticles, which can be toxic to humans. These nanoparticles were found in coal ash, city streets, and even wastewater treatment plants worldwide.
Researchers at Hebrew University developed novel nanoparticles for 3D printing in water, offering tunable properties and high light sensitivity. This breakthrough enables the creation of bio-friendly structures, tailored fabrication of medical devices, and environmentally friendly additive manufacturing.
Researchers developed a new non-toxic contrast agent for magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA), surpassing gadolinium's limitations. The agent, PEG-IONCs, demonstrated high biocompatibility in rabbits, beagle dogs, and macaque monkeys, showing promise as a next-generation diagnostic tool.
Researchers at Tokyo Institute of Technology developed a method to synthesize microscopic alloy nanoparticles using dendrimers, achieving 24 times greater oxidization activity than commercially available catalysts. The discovery opens up new possibilities for creating high-performance materials in various fields.
Researchers developed nanoparticles loaded with curcumin, a common spice compound, to target and destroy treatment-resistant neuroblastoma tumor cells. The study showed promising results in killing cancer cells while producing minimal toxicity in healthy cells.
This research reviews the use of probiotics for producing metallic nanoparticles (MNPs), which have potential applications in treating diseases and diagnosing conditions. Gold, silver, copper and zinc oxide NPs are suggested for drug delivery, antimicrobial activity, and anti-corrosive properties.
Researchers found that titanium dioxide nanoparticles can increase inflammation and damage to the intestinal mucosa in mice with colitis. Patients with colitis are recommended to avoid foods containing E171, a food additive made from titanium dioxide.
University scientists at Swansea University and Islamic Azad University have developed a new class of materials suitable agents for oil displacing in enhanced oil recovery. The nanoparticle-surfactant complexes improved oil recovery by 58% compared to 45% recovery in the presence of surfactant alone.
Researchers developed a nanoparticle-based adhesive that exhibits imaging contrast effect in CT and ultrasound, is biocompatible, and ensures accurate target localization during movement. The new glue has shown less toxicity than FDA-approved options and was successfully tested in animal models for various surgical procedures.
A University of Michigan team has created a method to add metallic nanoparticles into semiconductors with virtually no added manufacturing cost. The process enhances LED lighting efficiency and allows for precise control over the distribution of particles, potentially enabling future applications such as invisibility cloaks.
Researchers developed ceria-zirconia nanoparticles to treat sepsis by removing harmful oxygen radicals and reducing inflammatory responses. The nanoparticles improved survival rates by 2.5 fold in mice with sepsis, offering a new therapeutic strategy for this deadly disease.
A new nanoparticle 'buckyswitch' developed by Clemson researchers improves microscopic imaging resolution by allowing microscopes to capture images up to the terapixel level. This innovation overcomes the diffraction limit constraint and enables clearer visualization of small cellular structures.
A novel theory explains how metal nanoparticles form, revealing a balance between bond strength and ligand binding. This understanding enables the creation of more efficient and sustainable nanoparticle production processes for applications like biolabeling and targeted drug delivery.
A team led by Gang Han has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging (MRI) contrast that can be easily cleared by the body. This discovery holds promise for clinical applications, including enhanced MRI contrast for early-stage tumor detection.
Researchers developed silver-silica nanoparticles with an ampicillin coating that target antibiotic-resistant bacteria while being inert to human cells. The nanoantibiotic showed efficacy against both resistant and non-resistant strains of E. coli, offering a promising strategy for combating drug-resistant infections.
Korean scientists report that ceria-zirconia nanoparticles act as effective scavengers of oxygen radicals, promoting a greatly enhanced surviving rate in sepsis model organisms. The nanoparticles accumulate in organs where severe immune responses occur and successfully eradicate reactive oxygen species.
Scientists harness immune system's detection of cancer proteins to improve treatment, showing 20% complete response in preclinical melanoma models. The 'sticky' nanoparticles work synergistically with immunotherapy drugs to increase immune cell response.
Researchers at Empa investigate microfiber release from polyester textiles during washing, finding constant fiber quantity regardless of temperature or wash cycle duration. The study reveals a lack of effect from washing agents and detergents on microfiber release.
Exosomes, tiny biological nanoparticles, have shown promise in detecting and treating diseases such as cancer and Parkinson's. Researchers believe they can activate immune responses, deliver therapeutic molecules, and even serve as biomarkers for disease detection.
Researchers developed a new photocatalyst by integrating Cu2O nanoparticles with H2Ti3O7 nanotubes, showing improved photocatalytic activities for organic pollutant degradation. The composite exhibits stronger visible spectral response and wider absorbance, reducing bandgap energy and inhibiting electron-hole pair recombination.
Researchers developed a new drug delivery platform that uses ultrasound waves to trigger the dispersal of chemotherapy-containing nanoparticles precisely at tumor sites. The platform resulted in a two-fold increase in targeting efficacy and a dramatic reduction in both tumor size and drug-related toxicity.
Scientists have developed a new, inexpensive technique to create color-shifting nanoparticles inspired by beetle shells. The method produces tiny particles that can be easily controlled, enabling adjustable colors within materials or fabrics. This breakthrough could lead to the production of easier-to-read sensors and anti-tampering tags.
Assemblies of metallic nanoparticles behave like bulk magnets, displaying intriguing shape-dependent behavior that could improve high-density information storage technologies. The structures' magnetic behavior is influenced only by the shape of the assemblies, revealing a single bulk ferromagnet.
The NANOaers project investigates airborne nanoparticle mixtures and their impact on respiratory health. Researchers analyze the behavior of nanoparticles with other chemicals, aiming to predict their fate and potential health effects.
Researchers at Swansea University have created a new class of nanomaterials with tunable wettability, which can be used for antifouling and water-proofing surfaces. The materials are inexpensive, non-toxic, and can be applied via spray or spin-coating to various surfaces.
Scientists used computational models to investigate heterostructured nanoparticles and found that atomistic defects can jeopardize solar cell performance. They predicted a new material with improved optical properties, opening doors for more efficient energy conversion.