Articles tagged with Nanoparticles
A team of University of Florida researchers has successfully used light to grow gold nanoprisms, enabling better control over the growth process. The discovery has significant implications for pharmaceuticals, medical equipment, and solar panels.
Researchers developed nanoparticles that target and deliver chemotherapy drugs to metastatic cancer tumors using radiation guidance. The approach exploits overexpression of P-selectin molecules in human cancers, allowing for selective tumor penetration.
Researchers at University of Houston discovered a graphene-based Janus amphiphilic nanosheet that achieves 15 percent tertiary oil recovery at a low concentration of 0.01 percent, comparable to expensive methods. This breakthrough makes the process more environmentally friendly and cost-effective.
A Northwestern University research team has developed a tool to rapidly test millions of nanoparticles at once, similar to gene chips in biology. The combinatorial library approach enables scientists to quickly identify the best nanoparticle size and composition for various applications.
Researchers discovered two unique structures for gold nanocluster Au144(SR)60, a previously known material, using advanced data analytics. This finding suggests the existence of polymorphic nanoparticles with different properties.
Researchers have designed DNA frames to connect nanoparticles into precisely structured lattices, enabling the creation of nanomaterials with tailored properties. The team's method uses DNA origami to self-assemble particles into desired shapes, reducing dependence on particle modification.
Researchers at Okinawa Institute of Science and Technology Graduate University have discovered a unique copper-silver nanoparticle structure resembling the Japanese glass fishing floats, known as ukidama. The 'ukidama' structure has properties that could be utilized in biomedical devices and nanotechnology.
Australian researchers have developed a method to embed light-emitting nanoparticles into glass without losing their properties. The new 'hybrid glass' combines nanoparticles' luminescence with glass' transparency and versatility, opening up possibilities for ultra-high-tech applications like biological sensing and 3D displays.
Researchers found that dentin's mechanical coupling between collagen protein fibers and mineral nanoparticles allows it to withstand extreme forces. The nanostructure design enables dentin to last longer than synthetic filling materials.
A U of T Engineering team has designed a simpler way to keep therapeutic proteins localized for long periods. They found that proteins can be released over several weeks without encapsulation by controlling electrostatic interactions between proteins and nanoparticles.
Researchers at MIT have developed an algorithm that can build complex DNA nanoparticles automatically, allowing for a broader range of applications in fields such as vaccine development and gene editing. The algorithm, known as DAEDALUS, can build any type of 3D shape with a closed surface, including shapes with holes.
Researchers developed a dual nanoparticle delivery system for piperlongumine and TRAIL, demonstrating increased therapeutic efficacy in vitro and in vivo. The system sensitizes cancer cells to TRAIL, leading to higher apoptotic rates and improved anti-cancer effects.
Researchers at ORNL have demonstrated a scalable method to produce semiconducting nanoparticles using bacteria-fed sugar at temperatures below 150 degrees Fahrenheit. This approach reduces production costs by approximately 90 percent compared to conventional methods, making it attractive for applications in electronics, displays, solar...
Researchers at Lomonosov Moscow State University develop nanoparticles that can efficiently penetrate into cancer cells, emitting light to aid in early diagnosis. The particles can also be used as targeted drug delivery systems, offering a promising approach for cancer treatment.
A new gene therapy has been developed to repair lungs damaged by chronic allergic asthma, reducing inflammation and improving airway structure and function. The study used a novel biodegradable platform to deliver the thymulin gene therapy, showing effective results in mice with experimental asthma.
Research highlights the effects of nanoparticles on platelet activation and plasmatic coagulation, a complex process essential for human life. Studies demonstrate that nanoparticles can alter hemostasis in various diseases, such as cancer and diabetes, emphasizing the need for thorough testing and regulation.
Scientists created a way to make tissues and organs clearer by linking molecules together, leaving lipids that cause opacity intact. This breakthrough allows tracking of nanoparticles at depths of over 1 millimeter, enabling better understanding of interactions with tumors and organs.
Researchers developed a technique to visualize lithium ion battery discharge mechanisms in nanosized iron-oxide material, revealing the intercalation and conversion reactions that occur during lithiation. The study provides insights into how to improve battery performance and increase their longevity.
Researchers found that six genes, including four from a peroxiredoxin family, were affected by titanium dioxide nanoparticles in human HeLa cells and monkey kidney cells. The effect was seen after 24-hour exposure, with changes of about 50% in enzyme expression.
Researchers investigate the interaction of nucleotide chains with metallic nanoparticles in carbon nanotubes using hybrid molecular dynamics simulation methods. The study highlights the potential of these systems for designing electronic diagnostic tools and drug delivery systems.
Researchers have developed nanoparticles that deliver antiobesity drugs directly to fat tissue, transforming white adipose tissue into brown and stimulating angiogenesis. The treatment resulted in a 10% weight loss in mice without adverse side effects.
Researchers at Washington University in St. Louis have found a way to improve the growth of protein-rich bean crops by using zinc oxide nanoparticles, reducing the need for rock phosphorus fertilizer. The nanoparticles increase nutrient uptake and enzyme activity, leading to a lesser need for external phosphorus application.
Researchers have developed zinc-oxide nanoparticles that can prevent the herpes simplex virus from entering cells and stimulate natural immunity to develop. The particles, called ZOTEN, work by attracting the virus and allowing immune cells to process it.
A biodegradable nanoparticle acts like a Trojan horse to convince the immune system not to attack an allergen, shutting down allergic reactions and preventing asthma attacks. The technology also shows promise in treating food allergies.
Drexel University researchers developed a strategy to overcome biological barriers in cancer medication delivery. By decorating nanovehicles with enzymes and adding an extra layer of polyethylene glycol, the particles can penetrate solid tumors more effectively, increasing antitumor efficacy.
Researchers developed nanoparticles that target CD98, a glycoprotein promoting inflammation in IBD. These particles showed anti-inflammatory capacity without toxicity, offering an alternative treatment to existing medications.
Researchers at Kansas State University have developed a method to capture X-ray images of nanoparticles in femtosecond sequences, providing insights into their interactions with intense laser light. The technique has applications in understanding aerosol formation, climate models, and the development of optoelectronics.
Scientists at the University of Helsinki and Okinawa Institute of Science and Technology have successfully grown iron nanoparticles in a cubic shape. The researchers used a mathematical model to understand the mechanisms behind this phenomenon, which is thermodynamically unexpected.
Scientists developed triple-stage nanoparticles that improve tumor penetration and release cisplatin in acidic conditions, enhancing its efficacy while reducing toxic side effects. The delivery system demonstrated significant improvements in anti-tumor activity against various cancer models.
Researchers developed a new technique using nanoparticles that deliver therapeutic payloads and glow green when cancer cells begin dying. This allows for early detection of treatment effectiveness, potentially improving patient outcomes and quality of life.
A novel nanotechnology-based approach detects c-myc mRNA biomarkers for early-stage colon cancer diagnosis. The technique uses peptide nucleic acid/silver nanoparticles to induce a reversible color change.
Researchers at Caltech demonstrate that nanoparticles can selectively target tumors while leaving adjacent healthy tissue intact. The study's findings suggest the presence of the EPR effect in humans, which could lead to more effective cancer therapies with fewer side effects.
Scientists discovered a novel metal-binding activity in MamO, a protease that helps build magnetic nanoparticles using a unique motif. The study found that this process has evolved convergently throughout the evolution of magnetosomes.
Dr. Nadja Spitzer, an assistant professor of biological sciences at Marshall University, has been awarded a $508,708 NSF CAREER grant to study the effects of silver nanoparticles on brain health in children and adults. Her research aims to fill the knowledge gap regarding the use of these particles in consumer products.
Researchers have discovered a way to create biodegradable packaging materials by infusing eggshell nanoparticles into a blend of polybutyrate adipate terephthalate and polylactic acid. The addition increases the material's flexibility, making it suitable for retail applications such as grocery bags and food containers.
Researchers have developed a synthetic nanoparticle that can simultaneously detect and treat atherosclerotic plaques, offering new hope for preventing deadly heart attacks and strokes. The nanoparticles use MRI to visualize plaque buildup and trigger a therapeutic response.
The IBS team developed a graphene-semiconductor catalytic nanodiode that enables the detection of hot electrons on platinum nanoparticles in real time. This breakthrough allows researchers to study the electronic effect on catalytic activity and potentially design improved catalytic materials with lower costs.
Researchers have elucidated new factors influencing particle deposition via solvent evaporation, crucial for microchip production. The study found that interplay between solvent convection and nanoparticle collective diffusion governs particle recede at contact lines.
Researchers developed a nanoparticle technology called Salipro to stabilize membrane proteins in a lipid environment, allowing for high-resolution studies of their structure and function. This enables the discovery of new drugs, therapeutic antibodies, and vaccines targeting these proteins.
Researchers from the Center for Nanoparticle Research design a novel therapeutic agent capable of impeding neuronal cell death associated with Alzheimer's disease. The treatment targets mitochondrial dysfunction and oxidative stress, offering new hope for treating this debilitating neurodegenerative disorder.
Researchers at the University of Toronto have developed shape-shifting nanoparticles that can target and deliver cancer drugs to specific tumor types. The system uses modular particles attached to DNA sequences to gain access to diseased tissue, minimizing collateral damage.
A University of Arizona-led research team found that short-term exposure to industrial nanoparticles used in semiconductor manufacturing poses little risk. The study analyzed the physical, chemical and biological attributes of four metal oxide nanomaterials and determined that they showed no adverse effects on human cells or bacteria.
Researchers have developed a new nanoparticle that kills tumor cells in the eye by mimicking an enzyme used by immune cells, extending survival of mice with advanced breast cancer. The treatment offers advantages such as producing toxins per hour and being activated by light.
Researchers found that ceria nanoparticles can reduce inflammation in the brain following a bleeding stroke by decreasing the secretion of inflammatory chemicals. In a lab experiment, macrophages treated with ceria nanoparticles showed less damage and water accumulation at the stroke site compared to untreated cells.
Researchers created a nanoparticle formulation of a targeted cancer drug that selectively targets tumors while sparing healthy tissue. The nanoparticle-encapsulated version showed improved efficacy and reduced side effects in rodent trials.
Engineers at Washington University in St. Louis have developed nanoparticles of calcium carbonate that can modulate pH in solid tumors, keeping cancer from growing. The compound changes the pH of the tumor environment, making it less acidic and preventing metastasis.
Researchers used mathematical calculations to create a complete picture of protein nanoparticle surface morphology, identifying structures most advantageous for vaccine design. This approach may lead to the development of cost-effective vaccines, including a malaria vaccine set to start clinical testing soon.
MIT researchers have developed a way to deliver CRISPR genome repair components more efficiently and safely, correcting mutated genes in 6 percent of liver cells in mice. The new approach has the potential to treat a range of diseases, including metabolic disorders and liver conditions.
Scientists have successfully delivered a CRISPR/Cas9 therapeutic to adult mice with Tyrosinemia type I, correcting 6% of the mutated FAH gene in liver cells. This breakthrough uses AAV and lipid nanoparticle delivery mechanisms, paving the way for potential human treatment.
A team of researchers has developed a new way to prevent preterm birth using nanoparticles, which deliver medication directly to the uterus without crossing the placenta. The treatment, called LIPINDORA, shows promise in reducing preterm labor and avoiding fetal risks.
A paper by Gugliotti et al. in Science reported on RNA-mediated metal-metal bond formation, but an investigation found authors falsified research data. The journal is taking steps to address the concerns and ensure the integrity of its publications.
A nanoparticle drug-delivery system that combines photodynamic therapy with a molecular therapy drug reduces tumor progression and metastasis in animal models. The treatment cuts off common treatment escape pathways, offering new possibilities for synchronized multidrug combination therapies.
Researchers at FAU have discovered that mother-of-pearl is formed through the aggregation of nanoparticles within an organic matrix, rather than crystallisation. This unique process, found in nature, has implications for developing new high-performance ceramics with improved mechanical properties.
Researchers developed bubble-pen lithography, a technique that uses microbubbles to inscribe nanoparticles onto a surface with precise control. This method allows for the creation of new materials and devices, such as metamaterials, with unique properties.
Researchers at the Weizmann Institute of Science have created miniature 'flasks' that can accelerate chemical reactions by trapping molecules in a highly selective manner. The dynamic and reversible clusters can be reused multiple times, making them useful for applications such as drug delivery and industrial manufacturing.
A team of researchers developed a method for guiding replacement cells to diseased vascular segments using nanoparticles, which demonstrated promising results in mice. The fresh cells exert their curative effect in these segments by producing nitric oxide and regulating blood vessel expansion.
Researchers at Toyohashi Tech and Duke University developed a new method to produce oxidation-resistant copper alloy nanoparticles, which can be used as the main component of affordable conductive inks. The production process is economical and environmentally friendly, making it suitable for the advancement of printed electronics.
Researchers induce self-photosensitization of M. thermoacetica with cadmium sulfide nanoparticles, enabling photosynthesis and synthesis of semiconductor nanoparticles for efficient solar-to-chemical production.
UCLA researchers have developed a super-strong yet light structural metal by infusing magnesium with dense silicon carbide nanoparticles, achieving record levels of specific strength and stiffness-to-weight ratio. The new metal has potential applications in airplanes, cars, mobile electronics, and biomedical devices.
Scientists at NIST developed a new recipe development tool using advanced math to predict the capabilities of polymer-nanoparticle mixtures. By modeling particle shapes more realistically, they created virtual nanoparticles that can analyze real-world particles and make general statements about their behavior in mixes.