Articles tagged with Nanoparticles
Researchers developed biocompatible and biodegradable nanoparticles with effective antibacterial activity against E. coli, S. aureus, and B. subtilis. The NPs disrupt bacterial walls, induce reactive oxygen species, and cause cell invagination, making them a promising antimicrobial agent.
Researchers developed a method to fabricate structured composite materials using directional bindings of shaped particles for predictable assembly. The approach uses linker molecules made of complementary strands of DNA to control the arrangement of particles, achieving long-range order in large-scale assemblies and clusters.
University at Buffalo researchers have discovered a way to easily and effectively fasten proteins to nanoparticles, showing promise for developing an HIV vaccine and targeting cancer cells. The new biotechnology uses modified proteins and nanoparticles made of natural pigments and metal, and has been tested with impressive results.
Researchers at Purdue University have developed a new method to mass-produce electronic circuits made of liquid-metal alloys using inkjet printing. This technology enables the creation of stretchable garments and pliable robots that can interact with computers or provide therapeutic benefits. The approach involves dispersing liquid met...
Researchers analyzed cytotoxicity and non-specific cellular uptake of upconversion nanoparticles (UCNPs) in human skin cells. UCNPs convert near-infrared radiation to visible light, allowing for detection and monitoring of cancerous cells.
Scientists at CHOP use biodegradable nanoparticles to deliver anticancer drugs selectively to tumors, inhibiting growth and prolonging survival in animal models. The approach exploits the EPR effect, allowing for efficient delivery while avoiding toxicity in healthy tissues.
Researchers develop a novel way to apply drugs to dental plaque using nanoparticles that release antibacterial agents in response to acidic environments. This innovation has shown promising results in reducing the severity of cavities and promoting better oral health.
Researchers at Princess Margaret Cancer Centre successfully converted microbubble technology into nanoparticles that retain their imaging properties. The discovery has the potential to enhance drug delivery, prolong tumour visualization, and improve cancer treatment precision.
Researchers from the University of Montreal developed nanorobotic agents that can open the blood-brain barrier, allowing therapeutic molecules to be delivered directly to the brain. The technique involves using magnetic nanoparticles and radio-frequency fields to create a temporary opening in the barrier.
Researchers developed a new technique to visualize and track molecules in real-time, revealing their dynamic behavior in living cells. This provides a more realistic picture of how molecules move within cells, shedding light on previously hidden factors involved in nanocrystal assembly.
Scientists convert packing peanuts into high-tech carbon microsheets and nanoparticles for use in rechargeable batteries, achieving higher energy storage capacity than existing materials. The new process uses lower temperatures and produces more environmentally friendly materials.
Researchers successfully used green tea compounds to enhance imaging of cancer tumors in mice via MRIs. The novel agents showed a strong contrast between tumor and non-tumor cells, suggesting promising candidates for future use.
Scientists have created nanoparticles loaded with clarithromycin, an antibiotic used in respiratory infections treatment, allowing better delivery of the drug to lung cells. This method enables direct access to bacterial biofilms or individual lung cells, reducing toxic effects and improving treatment efficacy.
Researchers at MIT have developed a method to stimulate brain tissue using external magnetic fields and injected magnetic nanoparticles. The approach can provide an implant-free means of providing brain stimulation and mapping, potentially treating neurological diseases such as Parkinson's disease.
A study suggests that traditional water pretreatment methods such as coagulation, flocculation, and sedimentation are insufficient to remove titanium dioxide nanoparticles from water. The results highlight the need for improved treatment processes to address emerging engineered nanoparticle risks.
A review by Virginia Tech scientist Maren Roman highlights discrepancies in studies about cellulose nanocrystals' impact on the respiratory system, gastrointestinal tract, skin, and cells. More research is needed to determine their potential adverse health effects.
Researchers have developed a new light therapy that can reach deep tumors using nanoparticles and FDG, producing different kinds of free radicals that overwhelm tumor cells. This treatment shows promise in reducing cancer growth and increasing survival rates with minimal toxic side effects.
Researchers at Johns Hopkins Medicine discovered a way to prevent rejection in corneal transplants using biodegradable nanoparticles that release medication into the eye after surgery. The treatment showed 100% efficacy in animal studies, offering hope for improving medicine compliance and patient outcomes.
Dartmouth College researchers create a new class of flower-shaped magnetic nanoparticles that heat at low field strengths, showing improved performance compared to commercially available counterparts. This breakthrough could enable treatment of deep-seated tumors like pancreatic cancer.
UC Riverside researchers develop unique model system to study environmental effects of copper nanoparticles. The studies show that properly functioning septic tanks can eliminate toxicity of nanoparticles, providing encouraging results for human health and ecosystem implications.
Researchers at Houston Methodist have developed magnetic nanoparticles that can destroy blood clots 100 to 1,000 times faster than a commonly used clot-busting technique. The nanoparticles are coated in albumin and loaded with the drug tPA, allowing it to reach the clot more effectively.
Researchers developed targeted biodegradable nano-drones that deliver an anti-inflammatory drug to fat deposits in arteries, successfully restructuring atherosclerotic plaques to make them more stable. The treatment reduced reactive oxygen species, increased collagen, and decreased plaque necrotic core.
Researchers at Columbia University Irving Medical Center developed nanoparticles that deliver a special type of healing molecule to fat deposits in arteries, slowly releasing the drug and repairing damage. The approach avoids common side effects and may prevent heart attacks by targeting inflammation hotspots.
INRS researchers found that silver nanoparticles induce stress in the endoplasmic reticulum, triggering an inflammatory response and potentially leading to nanotoxicity. The study suggests a new mechanism of action for these particles, which could have implications for cancer treatment.
A German-American research team has determined the three-dimensional shape of free-flying silver nanoparticles for the first time, using DESY's X-ray laser FLASH. The tiny particles exhibit an unexpected variety of shapes, including Platonic and Archimedean bodies.
Researchers at Johns Hopkins Medicine have developed a new nanoparticle-based gene therapy that effectively kills brain cancer cells in rats and lengthens their survival. The treatment uses biodegradable nanoparticles filled with genes for an enzyme that turns a compound into a potent killer of cancer cells.
Researchers have discovered that silver nanoparticles' toxicity can be modulated by carbohydrate coatings, according to a recent study published in the Journal of Nanobiotechnology. The study found that glucose-coated silver nanoparticles are more toxic than those coated with galactose or mannose.
University at Buffalo researchers have designed a nanoparticle that can be detected by six medical imaging techniques, including CT scanning, PET scanning, and photoacoustic imaging. This technology has the potential to provide doctors with clearer pictures of patients' organs and tissues, enabling faster diagnosis and treatment.
Researchers at the University of Warwick have developed a new triggered-release mechanism for nanoparticles that could improve drug delivery and reduce side effects. The mechanism uses two nanoparticles to release medication only when taken into cells, potentially leading to more effective treatments with fewer side effects.
Researchers suggest that the tumor microenvironment could play a significant role in cancer treatment and delivery of nanoparticle-based drugs. They found varying levels of drug delivery between two triple-negative breast cancer tumors, highlighting the importance of personalized medicine and better profiling of tumors.
Researchers at UCSB's Reich Group have developed a method for spatially and temporally controlling the release of proteins inside cells using near-infrared laser-activated nanocarriers. This technology allows for targeted protein delivery, enabling new avenues for basic research and therapeutic applications.
A new method enhances direct methanol fuel cell efficiency by removing toxic heavy metal ions like Cr(VI) while converting to less toxic Cr(III). This allows for improved performance and increased power density.
A Rice University study examines how nanoparticles move through the food chain, tracing uptake and accumulation in plant roots, leaves, and caterpillars. The research found significant variation in nanoparticle accumulation rates based on surface coating types, with negatively charged particles avoiding clumping altogether.
Researchers at Brunel University London found proteins that disguise nanoparticles, allowing them to target cancer cells without causing inflammation. This discovery has potential for treating inflammatory diseases like Parkinson's and Alzheimer's, and glioblastoma brain tumors.
Researchers create dye-functionalized nanoparticles that selectively deliver siRNA to liver cells, reducing cholesterol production and offering new hope for personalized therapy approaches. The method uses near-infrared fluorescent dyes as address labels and tracking numbers, allowing for non-invasive monitoring of the transport process.
Researchers have developed novel nanoparticle designs that detect and destroy cancer cells using photo-thermal therapy, detecting tumors early and killing them simultaneously. The nanoparticles target specific proteins on cancer cells, releasing heat that burns the abnormal cells without harming normal ones.
Queen's University scientists found that nanosilver can upset the human gut community at low concentrations. The discovery highlights the potential risks of nanoparticles in everyday life and underscores the need for further research on their long-term effects on health.
Researchers at the University of Michigan found that circularly polarized light can influence the self-assembly of nanoparticles into chirally specific structures. This phenomenon has implications for understanding homochirality and potentially developing new methods for inducing chirality in molecules.
New nanoparticles can perform magnetic resonance imaging (MRI) and fluorescent imaging simultaneously, allowing for the tracking of specific molecules produced in the body. The particles were demonstrated to detect vitamin C in mice, showing strong fluorescent signals where vitamin C is present but little MRI contrast.
Bio-inspired bleeding control is achieved through the synthesis of platelet-like nanoparticles that mimic the human body's own coagulation processes. These tiny particles can be added to blood flow to supply or augment the patient's natural platelet supply, stemming bleeding and initiating healing.
Researchers develop composite material that harnesses visible light to degrade endocrine disruptors, including BPA and phenol, in a promising breakthrough. The method offers a more efficient alternative to existing ultraviolet light-based approaches.
Poorly executed nanosafety experiments have led to a lack of new knowledge, with most projects being irreproducible due to inadequate particle characterization. The 'NanoScreen' programme aims to address this issue by providing pre-validated methods for lab experiments using standardized test materials.
The study demonstrates that thermosponge nanoparticles can effectively deliver a variety of proteins while preserving their biological activity. The new platform is designed to eliminate the need for harsh solvents and shows promise for delivering protein-based drugs for human therapeutics.
Scientists developed a deeper understanding of ideal mesoporous nanoparticle design to maximize catalytic output. They modeled molecular movement within narrow channels and found that the optimal channel diameter balances pore size with reactant and product passage.
A novel strategy combining nanoparticle technology with FDA-approved photodynamic therapy has been developed to effectively kill deep-set cancer cells in vivo. The treatment uses low-power, deep-tissue-penetrating light to activate the cancer-killing drug, showing improved destruction of tumors with minimal damage to surrounding tissue.
Researchers found that metal nanoparticles appear to be liquid droplets on the outside but maintain a stable crystal configuration within. This phenomenon, known as Coble pseudoelasticity, could impact nanotechnology applications.
Researchers at MIT have achieved a long-sought goal of creating particles that can emit a colorful fluorescent glow and be precisely manipulated into position within living cells using magnetic fields. The new technology could enable tracking the position of nanoparticles as they move within the body or inside a cell, and manipulate th...
Researchers at Wyss Institute have developed a method to form tiny 3D metal nanoparticles in prescribed shapes using DNA as a construction mold. The breakthrough has the potential to advance laser technology, microscopy, solar cells and more.
Researchers at the University of Waterloo developed nanoparticle eye drops that can treat dry eye syndrome with just one weekly application. The drops deliver a precise amount of medication over five days, reducing irritation and excessive use of traditional eye drops.
A Swiss research team has revealed that nanoparticles are attracted to fingermarks through chemical bonding, rather than electrostatically. This discovery could lead to more accurate and sensitive techniques for detecting previously undetectable fingermarks, improving forensic science.
Researchers developed stealthy nanoparticles that successfully deliver cancer vaccines to a subset of macrophages deep inside lymph nodes, hindering tumor growth. The nanoparticles bypass circulating immune cells and enter the lymph nodes' core, where they are engulfed by special kind of macrophage.
A Duke University team found that nanoparticles called single-walled carbon nanotubes accumulate rapidly in wetland sediments, potentially harming aquatic food chains. The accumulation of these nanoparticles in sediment poses concerns for both sediment-dwelling organisms and animals that eat them.
A University of Texas at Arlington research team has developed a new method to fabricate transparent nanoscintillators that could advance medical safety and homeland security. The resulting scintillator material has better energy resolution than currently used materials, making it more effective for radiation detection.
The study compares the interactions between silver nanoparticles and two thiols, mercaptohexanol (MH) and cysteine. MH forms a sparingly soluble silver(I) thiolate complex AgSRm on the surface, while cysteine replaces the citrate capping agent to form cysteine capped nanoparticles.
A team of University of Pennsylvania researchers developed a technique to measure the electrical properties of nanoscale structures by passing them through tiny pores. By analyzing changes in ionic current, they found new ways to apply nanopore translocation to analyze objects at the smallest scale.
Researchers have discovered a crucial role of electronic and geometric effects in reducing carbon dioxide using gold-copper bimetallic nanoparticles. This breakthrough could lead to unprecedented improvements in electrochemical carbon dioxide reduction.
Researchers developed a T-MOC device to study tumor-microenvironment interactions, enabling the testing of nanoparticles and drugs targeting cancer. The chip can mimic human tumors, providing insights into targeted delivery methods.
A comprehensive look at lithium ion battery electrodes reveals that rapid-charging and high-power discharging may not damage the electrode as much as previously thought. The research suggests modifying electrodes or changing charging processes could promote uniform charging and discharging, extending battery life.
In a breakthrough study published in Nature Communications, Cedars-Sinai researchers successfully targeted stem cells to injured heart muscle using antibody-studded iron nanoparticles. This innovative approach enables precise localization of the body's own stem cells to the site of injury, promoting regeneration and repair.
Researchers have found that magnetite nanocubes can form chiral helices when exposed to an external magnetic field. The helices are formed through a balance of competing forces, including the Zeeman force and dipole-dipole magnetic force.