Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers have developed a new light therapy that can reach deep tumors using nanoparticles and FDG, producing different kinds of free radicals that overwhelm tumor cells. This treatment shows promise in reducing cancer growth and increasing survival rates with minimal toxic side effects.
Dartmouth College researchers create a new class of flower-shaped magnetic nanoparticles that heat at low field strengths, showing improved performance compared to commercially available counterparts. This breakthrough could enable treatment of deep-seated tumors like pancreatic cancer.
UC Riverside researchers develop unique model system to study environmental effects of copper nanoparticles. The studies show that properly functioning septic tanks can eliminate toxicity of nanoparticles, providing encouraging results for human health and ecosystem implications.
Researchers at Houston Methodist have developed magnetic nanoparticles that can destroy blood clots 100 to 1,000 times faster than a commonly used clot-busting technique. The nanoparticles are coated in albumin and loaded with the drug tPA, allowing it to reach the clot more effectively.
INRS researchers found that silver nanoparticles induce stress in the endoplasmic reticulum, triggering an inflammatory response and potentially leading to nanotoxicity. The study suggests a new mechanism of action for these particles, which could have implications for cancer treatment.
Researchers developed targeted biodegradable nano-drones that deliver an anti-inflammatory drug to fat deposits in arteries, successfully restructuring atherosclerotic plaques to make them more stable. The treatment reduced reactive oxygen species, increased collagen, and decreased plaque necrotic core.
Researchers at Columbia University Irving Medical Center developed nanoparticles that deliver a special type of healing molecule to fat deposits in arteries, slowly releasing the drug and repairing damage. The approach avoids common side effects and may prevent heart attacks by targeting inflammation hotspots.
A German-American research team has determined the three-dimensional shape of free-flying silver nanoparticles for the first time, using DESY's X-ray laser FLASH. The tiny particles exhibit an unexpected variety of shapes, including Platonic and Archimedean bodies.
Researchers at Johns Hopkins Medicine have developed a new nanoparticle-based gene therapy that effectively kills brain cancer cells in rats and lengthens their survival. The treatment uses biodegradable nanoparticles filled with genes for an enzyme that turns a compound into a potent killer of cancer cells.
Researchers have discovered that silver nanoparticles' toxicity can be modulated by carbohydrate coatings, according to a recent study published in the Journal of Nanobiotechnology. The study found that glucose-coated silver nanoparticles are more toxic than those coated with galactose or mannose.
University at Buffalo researchers have designed a nanoparticle that can be detected by six medical imaging techniques, including CT scanning, PET scanning, and photoacoustic imaging. This technology has the potential to provide doctors with clearer pictures of patients' organs and tissues, enabling faster diagnosis and treatment.
Researchers at the University of Warwick have developed a new triggered-release mechanism for nanoparticles that could improve drug delivery and reduce side effects. The mechanism uses two nanoparticles to release medication only when taken into cells, potentially leading to more effective treatments with fewer side effects.
Researchers suggest that the tumor microenvironment could play a significant role in cancer treatment and delivery of nanoparticle-based drugs. They found varying levels of drug delivery between two triple-negative breast cancer tumors, highlighting the importance of personalized medicine and better profiling of tumors.
Researchers at UCSB's Reich Group have developed a method for spatially and temporally controlling the release of proteins inside cells using near-infrared laser-activated nanocarriers. This technology allows for targeted protein delivery, enabling new avenues for basic research and therapeutic applications.
A new method enhances direct methanol fuel cell efficiency by removing toxic heavy metal ions like Cr(VI) while converting to less toxic Cr(III). This allows for improved performance and increased power density.
A Rice University study examines how nanoparticles move through the food chain, tracing uptake and accumulation in plant roots, leaves, and caterpillars. The research found significant variation in nanoparticle accumulation rates based on surface coating types, with negatively charged particles avoiding clumping altogether.
Researchers at Brunel University London found proteins that disguise nanoparticles, allowing them to target cancer cells without causing inflammation. This discovery has potential for treating inflammatory diseases like Parkinson's and Alzheimer's, and glioblastoma brain tumors.
Researchers create dye-functionalized nanoparticles that selectively deliver siRNA to liver cells, reducing cholesterol production and offering new hope for personalized therapy approaches. The method uses near-infrared fluorescent dyes as address labels and tracking numbers, allowing for non-invasive monitoring of the transport process.
Researchers have developed novel nanoparticle designs that detect and destroy cancer cells using photo-thermal therapy, detecting tumors early and killing them simultaneously. The nanoparticles target specific proteins on cancer cells, releasing heat that burns the abnormal cells without harming normal ones.
Researchers at the University of Michigan found that circularly polarized light can influence the self-assembly of nanoparticles into chirally specific structures. This phenomenon has implications for understanding homochirality and potentially developing new methods for inducing chirality in molecules.
Queen's University scientists found that nanosilver can upset the human gut community at low concentrations. The discovery highlights the potential risks of nanoparticles in everyday life and underscores the need for further research on their long-term effects on health.
New nanoparticles can perform magnetic resonance imaging (MRI) and fluorescent imaging simultaneously, allowing for the tracking of specific molecules produced in the body. The particles were demonstrated to detect vitamin C in mice, showing strong fluorescent signals where vitamin C is present but little MRI contrast.
Bio-inspired bleeding control is achieved through the synthesis of platelet-like nanoparticles that mimic the human body's own coagulation processes. These tiny particles can be added to blood flow to supply or augment the patient's natural platelet supply, stemming bleeding and initiating healing.
Researchers develop composite material that harnesses visible light to degrade endocrine disruptors, including BPA and phenol, in a promising breakthrough. The method offers a more efficient alternative to existing ultraviolet light-based approaches.
Poorly executed nanosafety experiments have led to a lack of new knowledge, with most projects being irreproducible due to inadequate particle characterization. The 'NanoScreen' programme aims to address this issue by providing pre-validated methods for lab experiments using standardized test materials.
The study demonstrates that thermosponge nanoparticles can effectively deliver a variety of proteins while preserving their biological activity. The new platform is designed to eliminate the need for harsh solvents and shows promise for delivering protein-based drugs for human therapeutics.
Scientists developed a deeper understanding of ideal mesoporous nanoparticle design to maximize catalytic output. They modeled molecular movement within narrow channels and found that the optimal channel diameter balances pore size with reactant and product passage.
A novel strategy combining nanoparticle technology with FDA-approved photodynamic therapy has been developed to effectively kill deep-set cancer cells in vivo. The treatment uses low-power, deep-tissue-penetrating light to activate the cancer-killing drug, showing improved destruction of tumors with minimal damage to surrounding tissue.
Researchers found that metal nanoparticles appear to be liquid droplets on the outside but maintain a stable crystal configuration within. This phenomenon, known as Coble pseudoelasticity, could impact nanotechnology applications.
Researchers at MIT have achieved a long-sought goal of creating particles that can emit a colorful fluorescent glow and be precisely manipulated into position within living cells using magnetic fields. The new technology could enable tracking the position of nanoparticles as they move within the body or inside a cell, and manipulate th...
Researchers at Wyss Institute have developed a method to form tiny 3D metal nanoparticles in prescribed shapes using DNA as a construction mold. The breakthrough has the potential to advance laser technology, microscopy, solar cells and more.
Researchers at the University of Waterloo developed nanoparticle eye drops that can treat dry eye syndrome with just one weekly application. The drops deliver a precise amount of medication over five days, reducing irritation and excessive use of traditional eye drops.
Researchers developed stealthy nanoparticles that successfully deliver cancer vaccines to a subset of macrophages deep inside lymph nodes, hindering tumor growth. The nanoparticles bypass circulating immune cells and enter the lymph nodes' core, where they are engulfed by special kind of macrophage.
A Duke University team found that nanoparticles called single-walled carbon nanotubes accumulate rapidly in wetland sediments, potentially harming aquatic food chains. The accumulation of these nanoparticles in sediment poses concerns for both sediment-dwelling organisms and animals that eat them.
A Swiss research team has revealed that nanoparticles are attracted to fingermarks through chemical bonding, rather than electrostatically. This discovery could lead to more accurate and sensitive techniques for detecting previously undetectable fingermarks, improving forensic science.
A University of Texas at Arlington research team has developed a new method to fabricate transparent nanoscintillators that could advance medical safety and homeland security. The resulting scintillator material has better energy resolution than currently used materials, making it more effective for radiation detection.
The study compares the interactions between silver nanoparticles and two thiols, mercaptohexanol (MH) and cysteine. MH forms a sparingly soluble silver(I) thiolate complex AgSRm on the surface, while cysteine replaces the citrate capping agent to form cysteine capped nanoparticles.
A team of University of Pennsylvania researchers developed a technique to measure the electrical properties of nanoscale structures by passing them through tiny pores. By analyzing changes in ionic current, they found new ways to apply nanopore translocation to analyze objects at the smallest scale.
Researchers have discovered a crucial role of electronic and geometric effects in reducing carbon dioxide using gold-copper bimetallic nanoparticles. This breakthrough could lead to unprecedented improvements in electrochemical carbon dioxide reduction.
Researchers developed a T-MOC device to study tumor-microenvironment interactions, enabling the testing of nanoparticles and drugs targeting cancer. The chip can mimic human tumors, providing insights into targeted delivery methods.
A comprehensive look at lithium ion battery electrodes reveals that rapid-charging and high-power discharging may not damage the electrode as much as previously thought. The research suggests modifying electrodes or changing charging processes could promote uniform charging and discharging, extending battery life.
In a breakthrough study published in Nature Communications, Cedars-Sinai researchers successfully targeted stem cells to injured heart muscle using antibody-studded iron nanoparticles. This innovative approach enables precise localization of the body's own stem cells to the site of injury, promoting regeneration and repair.
Researchers have found that magnetite nanocubes can form chiral helices when exposed to an external magnetic field. The helices are formed through a balance of competing forces, including the Zeeman force and dipole-dipole magnetic force.
A new synthesis method enables the creation of nanostructures that efficiently split water into hydrogen fuel using sunlight. The approach allows for the design and construction of higher-order nanostructures with specific symmetries or shapes, enabling potential applications in quantum computing, sensors, and clean energy.
Researchers at Washington University in St. Louis developed a new sensor that can detect and count nanoparticles as small as 10 nanometers, one at a time. The sensor uses Raman microlasing technology to achieve high sensitivity and biocompatibility.
Researchers develop new method to quantify and correlate biological aggregation effects on radiofrequency heating and MRI contrast of magnetic iron oxide nanoparticles. The study presents a platform for accounting for aggregation in clinical applications, such as cancer hyperthermia.
Researchers have developed dynamic nanoparticles that can be used as contrast agents for MRI and PET scans, deliver chemotherapy directly to tumors, and respond to light to destroy tumor cells. The particles are biocompatible, non-toxic, and can be easily made, making them a promising tool in cancer treatment.
Researchers at MIPT and RAS made a significant step towards creating medical nanorobots by enabling nanoparticles to produce logical calculations. The discovery paves the way for biomedical technologies, including selective binding to target cells and analyzing biological materials.
A new chip-based platform combines electrical and optical measurements to study single molecules and nanoparticles. The device allows for the discrimination of particles with different sizes and optical properties, enabling reliable counts of virus particles.
Scientists have devised a method to target venom proteins specifically to malignant cells while sparing healthy ones, reducing or eliminating side effects. The approach involves using tiny nanometer-sized particles to treat breast and melanoma cancer cells in the laboratory.
Weizmann Institute scientists have created twisted, rope-like structures from cube-shaped nanoparticles, demonstrating the power of self-assembly in nanomaterials. The findings reveal how competing forces like magnetism and van der Waals forces can align particles into complex shapes.
A new imaging agent has been developed for functional imaging of the intestine, potentially leading to better diagnosis and treatment of gut diseases. The agent uses a combination of photoacoustic imaging and positron emission tomography to provide high-definition images of the intestine in relation to the entire body.
Researchers at NIST have clocked nanorods spinning up to 150,000 revolutions per minute, 10 times faster than any other nanoscale object in liquid. This discovery has opened up potential uses for nanomotors in medical treatments and industrial processes.
Mathew M. Maye's research may lead to gas storage, heterogeneous catalysis, and rechargeable lithium-ion batteries applications. He is developing novel synthesis strategies for stainless nanoparticle alloys with controlled oxidation properties.
Scientists have designed a new self-assembling nanoparticle that targets tumours to improve MRI scanning's effectiveness and sensitivity. The particle increases the signal power and clarity of images, allowing doctors to detect cancerous cells earlier.
Researchers developed nanojuice to improve non-invasive gut imaging, providing real-time views of the small intestine. This technique may help diagnose irritable bowel syndrome, celiac disease, Crohn's disease, and other gastrointestinal illnesses.
Researchers have developed nanoparticles that increase survival rates and show no signs of interference in healing after blast trauma. The artificial platelets, called hemostatic nanoparticles, were found to be effective in stopping bleeding and increasing survival rates.
Researchers discovered that molybdenum trioxide nanoparticles can mimic the function of sulfite oxidase, an enzyme responsible for cellular detoxification processes. The nanoparticles can cross cell membranes and accumulate at mitochondria, recovering sulfite oxidase activity and potentially treating sulfite oxidase deficiency.
Researchers have developed a method to produce silver nanostructures using high-pressure diamond plates, outperforming traditional chemical methods. This approach enables the creation of flexible electronics, transparent electrodes, and new classes of chemically and mechanically stable nanostructures.
Scientists from Norway, France, and Poland develop a method to produce Janus capsules, which can transport drugs and lead to innovative materials. The capsules are created by merging two drops coated with different particles in an electric field, resulting in a hollow structure with two shells of varying properties.