Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers developed a technique to visualize lithium ion battery discharge mechanisms in nanosized iron-oxide material, revealing the intercalation and conversion reactions that occur during lithiation. The study provides insights into how to improve battery performance and increase their longevity.
Researchers found that six genes, including four from a peroxiredoxin family, were affected by titanium dioxide nanoparticles in human HeLa cells and monkey kidney cells. The effect was seen after 24-hour exposure, with changes of about 50% in enzyme expression.
Researchers investigate the interaction of nucleotide chains with metallic nanoparticles in carbon nanotubes using hybrid molecular dynamics simulation methods. The study highlights the potential of these systems for designing electronic diagnostic tools and drug delivery systems.
Researchers have developed nanoparticles that deliver antiobesity drugs directly to fat tissue, transforming white adipose tissue into brown and stimulating angiogenesis. The treatment resulted in a 10% weight loss in mice without adverse side effects.
Researchers at Washington University in St. Louis have found a way to improve the growth of protein-rich bean crops by using zinc oxide nanoparticles, reducing the need for rock phosphorus fertilizer. The nanoparticles increase nutrient uptake and enzyme activity, leading to a lesser need for external phosphorus application.
Researchers have developed zinc-oxide nanoparticles that can prevent the herpes simplex virus from entering cells and stimulate natural immunity to develop. The particles, called ZOTEN, work by attracting the virus and allowing immune cells to process it.
A biodegradable nanoparticle acts like a Trojan horse to convince the immune system not to attack an allergen, shutting down allergic reactions and preventing asthma attacks. The technology also shows promise in treating food allergies.
Drexel University researchers developed a strategy to overcome biological barriers in cancer medication delivery. By decorating nanovehicles with enzymes and adding an extra layer of polyethylene glycol, the particles can penetrate solid tumors more effectively, increasing antitumor efficacy.
Researchers developed nanoparticles that target CD98, a glycoprotein promoting inflammation in IBD. These particles showed anti-inflammatory capacity without toxicity, offering an alternative treatment to existing medications.
Researchers at Kansas State University have developed a method to capture X-ray images of nanoparticles in femtosecond sequences, providing insights into their interactions with intense laser light. The technique has applications in understanding aerosol formation, climate models, and the development of optoelectronics.
Scientists at the University of Helsinki and Okinawa Institute of Science and Technology have successfully grown iron nanoparticles in a cubic shape. The researchers used a mathematical model to understand the mechanisms behind this phenomenon, which is thermodynamically unexpected.
Scientists developed triple-stage nanoparticles that improve tumor penetration and release cisplatin in acidic conditions, enhancing its efficacy while reducing toxic side effects. The delivery system demonstrated significant improvements in anti-tumor activity against various cancer models.
Researchers developed a new technique using nanoparticles that deliver therapeutic payloads and glow green when cancer cells begin dying. This allows for early detection of treatment effectiveness, potentially improving patient outcomes and quality of life.
A novel nanotechnology-based approach detects c-myc mRNA biomarkers for early-stage colon cancer diagnosis. The technique uses peptide nucleic acid/silver nanoparticles to induce a reversible color change.
Researchers at Caltech demonstrate that nanoparticles can selectively target tumors while leaving adjacent healthy tissue intact. The study's findings suggest the presence of the EPR effect in humans, which could lead to more effective cancer therapies with fewer side effects.
Scientists discovered a novel metal-binding activity in MamO, a protease that helps build magnetic nanoparticles using a unique motif. The study found that this process has evolved convergently throughout the evolution of magnetosomes.
Dr. Nadja Spitzer, an assistant professor of biological sciences at Marshall University, has been awarded a $508,708 NSF CAREER grant to study the effects of silver nanoparticles on brain health in children and adults. Her research aims to fill the knowledge gap regarding the use of these particles in consumer products.
Researchers have discovered a way to create biodegradable packaging materials by infusing eggshell nanoparticles into a blend of polybutyrate adipate terephthalate and polylactic acid. The addition increases the material's flexibility, making it suitable for retail applications such as grocery bags and food containers.
Researchers have developed a synthetic nanoparticle that can simultaneously detect and treat atherosclerotic plaques, offering new hope for preventing deadly heart attacks and strokes. The nanoparticles use MRI to visualize plaque buildup and trigger a therapeutic response.
The IBS team developed a graphene-semiconductor catalytic nanodiode that enables the detection of hot electrons on platinum nanoparticles in real time. This breakthrough allows researchers to study the electronic effect on catalytic activity and potentially design improved catalytic materials with lower costs.
Researchers have elucidated new factors influencing particle deposition via solvent evaporation, crucial for microchip production. The study found that interplay between solvent convection and nanoparticle collective diffusion governs particle recede at contact lines.
Researchers developed a nanoparticle technology called Salipro to stabilize membrane proteins in a lipid environment, allowing for high-resolution studies of their structure and function. This enables the discovery of new drugs, therapeutic antibodies, and vaccines targeting these proteins.
Researchers from the Center for Nanoparticle Research design a novel therapeutic agent capable of impeding neuronal cell death associated with Alzheimer's disease. The treatment targets mitochondrial dysfunction and oxidative stress, offering new hope for treating this debilitating neurodegenerative disorder.
Researchers at the University of Toronto have developed shape-shifting nanoparticles that can target and deliver cancer drugs to specific tumor types. The system uses modular particles attached to DNA sequences to gain access to diseased tissue, minimizing collateral damage.
A University of Arizona-led research team found that short-term exposure to industrial nanoparticles used in semiconductor manufacturing poses little risk. The study analyzed the physical, chemical and biological attributes of four metal oxide nanomaterials and determined that they showed no adverse effects on human cells or bacteria.
Researchers have developed a new nanoparticle that kills tumor cells in the eye by mimicking an enzyme used by immune cells, extending survival of mice with advanced breast cancer. The treatment offers advantages such as producing toxins per hour and being activated by light.
Researchers found that ceria nanoparticles can reduce inflammation in the brain following a bleeding stroke by decreasing the secretion of inflammatory chemicals. In a lab experiment, macrophages treated with ceria nanoparticles showed less damage and water accumulation at the stroke site compared to untreated cells.
Researchers created a nanoparticle formulation of a targeted cancer drug that selectively targets tumors while sparing healthy tissue. The nanoparticle-encapsulated version showed improved efficacy and reduced side effects in rodent trials.
Engineers at Washington University in St. Louis have developed nanoparticles of calcium carbonate that can modulate pH in solid tumors, keeping cancer from growing. The compound changes the pH of the tumor environment, making it less acidic and preventing metastasis.
Researchers used mathematical calculations to create a complete picture of protein nanoparticle surface morphology, identifying structures most advantageous for vaccine design. This approach may lead to the development of cost-effective vaccines, including a malaria vaccine set to start clinical testing soon.
MIT researchers have developed a way to deliver CRISPR genome repair components more efficiently and safely, correcting mutated genes in 6 percent of liver cells in mice. The new approach has the potential to treat a range of diseases, including metabolic disorders and liver conditions.
Scientists have successfully delivered a CRISPR/Cas9 therapeutic to adult mice with Tyrosinemia type I, correcting 6% of the mutated FAH gene in liver cells. This breakthrough uses AAV and lipid nanoparticle delivery mechanisms, paving the way for potential human treatment.
A team of researchers has developed a new way to prevent preterm birth using nanoparticles, which deliver medication directly to the uterus without crossing the placenta. The treatment, called LIPINDORA, shows promise in reducing preterm labor and avoiding fetal risks.
A paper by Gugliotti et al. in Science reported on RNA-mediated metal-metal bond formation, but an investigation found authors falsified research data. The journal is taking steps to address the concerns and ensure the integrity of its publications.
A nanoparticle drug-delivery system that combines photodynamic therapy with a molecular therapy drug reduces tumor progression and metastasis in animal models. The treatment cuts off common treatment escape pathways, offering new possibilities for synchronized multidrug combination therapies.
Researchers at FAU have discovered that mother-of-pearl is formed through the aggregation of nanoparticles within an organic matrix, rather than crystallisation. This unique process, found in nature, has implications for developing new high-performance ceramics with improved mechanical properties.
Researchers developed bubble-pen lithography, a technique that uses microbubbles to inscribe nanoparticles onto a surface with precise control. This method allows for the creation of new materials and devices, such as metamaterials, with unique properties.
Researchers at the Weizmann Institute of Science have created miniature 'flasks' that can accelerate chemical reactions by trapping molecules in a highly selective manner. The dynamic and reversible clusters can be reused multiple times, making them useful for applications such as drug delivery and industrial manufacturing.
A team of researchers developed a method for guiding replacement cells to diseased vascular segments using nanoparticles, which demonstrated promising results in mice. The fresh cells exert their curative effect in these segments by producing nitric oxide and regulating blood vessel expansion.
Researchers at Toyohashi Tech and Duke University developed a new method to produce oxidation-resistant copper alloy nanoparticles, which can be used as the main component of affordable conductive inks. The production process is economical and environmentally friendly, making it suitable for the advancement of printed electronics.
Researchers induce self-photosensitization of M. thermoacetica with cadmium sulfide nanoparticles, enabling photosynthesis and synthesis of semiconductor nanoparticles for efficient solar-to-chemical production.
UCLA researchers have developed a super-strong yet light structural metal by infusing magnesium with dense silicon carbide nanoparticles, achieving record levels of specific strength and stiffness-to-weight ratio. The new metal has potential applications in airplanes, cars, mobile electronics, and biomedical devices.
Scientists at NIST developed a new recipe development tool using advanced math to predict the capabilities of polymer-nanoparticle mixtures. By modeling particle shapes more realistically, they created virtual nanoparticles that can analyze real-world particles and make general statements about their behavior in mixes.
A team of researchers from North Carolina State University has developed a technique for remotely controlling soft robots by manipulating elastic polymers with magnetic nanoparticles. By arranging the nanoparticles into parallel chains, they can control the movement and direction of the soft robots.
Researchers from McMaster University successfully tracked individual catalyst nanoparticles during heating using advanced electron microscopy techniques. This breakthrough could lead to the development of less expensive catalysts, such as platinum-iron nanoparticles, reducing dependence on imported oil and greenhouse gas emissions.
Berkeley Lab researchers model hot carrier movement in real-time, distinguishing between plasmon and single particle excitation behaviors. The study shows that 90% of plasmon energy can be converted to single particle energy when excitations are in tune.
Researchers have created more efficient nanoparticles in fuel cells, improving the conversion of methanol into electrical energy. The study provides guidelines for controlling the charge of nanoparticles, a crucial step in optimizing catalytic efficiency.
Multiple sclerosis may be triggered by the death of brain cells that make the insulation around nerve fibers. Nanoparticles have been shown to prevent progressive MS in an animal model, offering new hope for human treatments without side effects.
Researchers at FAU and University of Barcelona discovered that platinum nanoparticles lose approximately every tenth electron when in contact with oxide support. This effect can be controlled using theoretical methods, allowing for more efficient catalytic processes and new electronic components.
Scientists have reported a high-performance nanoparticle electrocatalyst for fuel cells, featuring durable and active PtFe nanoparticles coated with nitrogen-doped carbon shells. This breakthrough could lead to the development of more efficient and affordable fuel cell technology.
Researchers developed nanoparticles that target and burst when exposed to near-infrared laser light, releasing therapeutic agents that alter gene activity in cancer stem cells. The study used human prostate-cancer cells and tumors, showing promise for overcoming biological barriers to gene-regulating agents.
Researchers have developed a new method using microwaves to produce BiVO4 nanoparticles for cleaning wastewater, which is 20 times faster and saves energy compared to traditional methods.
Researchers at Oregon State University have discovered a fundamental flaw in the physics of photonic sintering, leading to improved product quality and process efficiency. The new understanding allows for high-quality products to be created at much lower temperatures, twice as fast and with 10 times more energy efficiency.
A new process removes contaminants from oil sands wastewater using sunlight and nanoparticles, offering a more effective and inexpensive alternative to conventional treatment methods. The technology breaks down persistent pollutants into individual atoms, completely removing them from the water.
A new technology uses oscillating electric fields to isolate drug-delivery nanoparticles from blood, overcoming traditional separation methods' limitations. The device can recover nanoparticles in various processes and monitor their interaction with blood proteins.
Researchers at Lund University estimate that sea traffic emissions account for almost half of measured particles in coastal air, exceeding previous estimates. Nanoparticles can penetrate deeper into the lungs than larger particles, contributing to health issues.
Researchers at Brigham and Women's Hospital have developed a new approach to predict which tumors will be most responsive to therapeutic nanoparticles. They use an FDA-approved magnetic nanoparticle and MRI to identify tumors with high or low EPR, a physiological condition that allows nanoparticles to accumulate faster.
Researchers at Vanderbilt University have discovered a way to overcome the limitations of nanoscale materials in batteries by using iron pyrite quantum dots. These ultrasmall nanoparticles allow for faster charging and longer cycle life, making them a promising solution for future battery technology.
Researchers at the University of Michigan found that zinc oxide nanopyramids can disrupt the growth of methicillin-resistant Staphylococcus aureus (MRSA) on medical implants, reducing bacterial load by over 95%. The coating may enable antibiotic treatments to succeed or allow the human immune system to take over.
Researchers at the University of York have developed a self-assembling gel that can selectively extract precious metals like silver and gold from electronic waste. The gel is then converted into conducting nanoparticles, enhancing its electrical conductance and making it suitable for various high-tech applications.