Articles tagged with Nanoparticles
Lipid nanoparticles (SLNs) have shown increased effectiveness in delivering nucleic acids, with advantages including protection against degradation and boost to transfection process. Researchers are exploring their application in treating various diseases, including degenerative disorders of the retina, infectious diseases, and cancer.
A new material has been developed using a simple method that can change color in response to environmental changes, making it suitable for use as sensors. The material also shows promise for bioimaging applications, allowing for non-invasive measurement of molecular interactions in real-time.
Researchers at Salk Institute use mRNA therapy to deliver instructions for clotting protein, achieving normal clotting and minimal immune response in mice. The therapy shows potential as a cost-effective and safer alternative to existing treatments for hemophilia B and other genetic diseases.
Researchers have developed a new technique to track the movement of cancer cells using reversible, photo-luminescent carbon nanoparticles. The study demonstrates that these particles can be used for intracellular imaging and drug delivery tracking without photo-bleaching issues.
Researchers have developed a direct radiolabeling method for nanomaterials using nanographene, eliminating the need for chelators. This approach significantly improves bioimaging accuracy and reduces biases. The method was tested in mice models and showed promising results.
Researchers at UMass Amherst have designed a novel nanoparticle-based delivery system to enhance CRISPR/Cas9's treatment potential for genetic diseases. The new delivery method achieved an editing efficiency of about 30 percent in cultured cells, with successful nuclear delivery in approximately 90 percent of cells.
Researchers have developed a new technique using DNA 'barcodes' to rapidly screen nanoparticles for therapeutic delivery. The method allows hundreds of different types of nanoparticles to be tested simultaneously in just a handful of animals.
Amélie Juhin, a physicist and spectroscopist, has been awarded the ESRF Young Scientist of the Year 2017 prize for her experimental and theoretical studies on resonant X-ray scattering and X-ray dichroism. Her research focuses on probing electronic and magnetic properties of nanoparticles and molecular magnets.
Researchers from Geneva and Fribourg have developed a rapid screening method to select the most promising nanoparticles for medical applications. The new approach can determine biocompatibility in under two days, reducing the need for animal testing and enabling personalized treatment.
Researchers used a combination of computational power and experimental data to study magnetism in a real iron-platinum nanoparticle. The team was able to precisely model the atomic structure and simulate its magnetic properties, revealing defects and imperfections that affect performance.
Researchers use advanced electron microscopy to create 3D reconstruction of nanoparticle, enabling them to measure chemical order and disorder at the single-atom level. The study reveals insights into the material's properties and potential applications in high-density hard drives and disease detection.
Researchers mapped over 23,000 individual atoms in an iron-platinum nanoparticle to reveal the material's defects and properties. The study reveals unique arrangements of atoms at grain boundaries, which significantly influence material properties.
Researchers demonstrate that massaging hair can increase the delivery of nanoparticles to hair follicles by creating channels for particle transport. The ratchet mechanism enhances particle speed and diffusion when massaged parallel to the resting surface.
Researchers at Duke University have developed a tiny device that uses sound waves to create whirlpools to gather proteins and other biomarkers from blood, urine or saliva samples. This innovative technology has the potential to form the basis of a small, inexpensive point-of-care device for early disease diagnosis.
Researchers at NIST have developed a new method to separate synthetic nanoparticles from living organisms, improving experiments on environmental and health impacts of manufactured entities. The sucrose density gradient centrifugation technique yields more accurate counts of ingested nanoparticles.
Biomedical engineers at Johns Hopkins create a method to deliver and release concentrated amounts of drugs to the brain using ultrasound pulses. The technique has the potential to advance many therapies and research studies, minimizing side effects and potentially bringing new treatments to humans within a year or two.
A UCF researcher has developed a method that uses nanoparticles and Faraday rotation to measure protein quantities in test solutions, allowing for faster biochemical immunology test results. This technique could lead to faster diagnoses for HIV, Lyme disease, syphilis, and other infectious conditions.
Researchers at Helmholtz Zentrum München found that nanoparticles from combustion engines can reactivate latent herpes viruses in lung tissue cells. This process can lead to increased viral proteins and acute infection patterns. Further studies aim to investigate the molecular mechanism of virus reactivation by nanoparticles.
Scientists captured real-time, dynamic visualizations of atoms moving in and out of nanoparticles less than 100 nanometers in size. The experiments provided insight into the chemical and physical sciences, revealing that nanoparticles can self-heal and become more durable energy storage materials.
Researchers have developed a revolutionary new crop protection technique using gene-silencing technology and nanotechnology to protect plants against pests and diseases. The BioClay spray has been shown to give plants virus protection for at least 20 days following a single application.
Researchers directly observed how metallic nanoparticles activate catalytic processes by identifying defect sites on the surface of single particles. These findings validate a longstanding hypothesis and provide insights into controlling catalyst reactivity.
Researchers at Aalto University developed a plasmonic nanolaser that operates at visible light frequencies and uses dark lattice modes, allowing for ultrafast and tiny coherent light sources. The nanolaser uses silver nanoparticles arranged in a periodic array, which radiate in unison to produce high-intensity laser light.
Researchers at Duke University have created a new method for printing conductive films using silver nanowire inks, eliminating the need for heat. The resulting printed electronics can be used in various applications such as solar cells, displays, and implantable bio-electronic devices.
This review explores the potential of nanoparticle drug delivery systems to improve solubility, permeability, and stability of ophthalmic drugs. The development of these systems may offer a solution to the limitations of traditional topically administered formulations.
Researchers at Oregon State University developed a new method for sintering nanoparticles using intense pulsed light, enabling faster and more efficient production of advanced flexible electronics. The breakthrough allows for larger areas to be processed in seconds, reducing the need for high-temperature equipment.
Researchers discovered that nanoparticles, resembling caterpillars, trigger immune system activation when internalized. To counteract this detection, three possible strategies are proposed: modifying the coating, understanding absorbed proteins, or attracting natural inhibitors.
Researchers developed RNA nanoparticles that selectively bind to HER2-overexpressing breast tumors, eliminating MED1 expression and sensitizing them to tamoxifen treatment. The nanoparticles also reduced cancer stem cell content, a promising strategy for treating advanced metastatic breast cancer.
Researchers used 3D imaging to study nanoscale details of nickel-cobalt particles, revealing a unique 'Swiss cheese' structure that increases surface area and reactivity. The findings could lead to more efficient and cost-effective catalysts for fuel cells.
Researchers have developed a simple and inexpensive method for stabilizing vaccines at room temperature using nanoparticles, polymers, or sugar. This approach could improve vaccine storage and distribution, especially in remote areas with limited refrigeration, reducing the cost of vaccination programs by nearly 80%.
Researchers propose a nanosized dipole photomotor controlled by a laser, capable of directed motion at record speed. The device has potential applications across the natural sciences and medicine, including delivering drugs to diseased tissues.
Researchers found that normal atmospheric conditions lead to the formation of oxygen-enriched silica nanoparticles with magnetic properties. These reactive oxygen species have been linked to cancer and may explain the known carcinogenicity of silica dust. The study provides a possible explanation for the high toxicity of silica dust.
Researchers at UMass Amherst developed polymer-stabilized droplet carriers that can recognize and encapsulate nanoparticles for transport in a cell. These 'nanoparticle taxicabs' pick up particles on one surface and drop them off on another, representing the first successful translation of biological processes in materials science.
A new gene-editing system successfully cured a genetic blood disorder in living mice, offering a minimally invasive treatment for beta thalassemia and sickle cell disease. The technology significantly decreases unwanted gene mutations and uses FDA-approved nanoparticles to deliver PNA molecules.
Researchers developed a new type of nanoparticle vaccine that effectively vaccinated mice against one dengue virus serotype. The vaccine targets only one strain, but its development could pave the way for vaccines against all four serotypes, potentially offering better protection against life-threatening disease.
Researchers have developed a highly active and stable catalyst for ammonia synthesis under low reaction temperatures. The flat-shaped Ru nanoparticles anchored on Ca(NH2)2 exhibit high catalytic performance and long-term stability.
The team aims to find and design more benign nanomaterials using advanced computational methods. They will use the XSEDE network to study nanoparticles, including their interactions with human health and the environment.
Researchers analyzed 300 published works on silver nanoparticles and wastewater treatment, finding no adverse effects at current concentrations. The team suggests that moderate or high concentrations could pose a problem in decades to come.
Researchers at the University of Texas at Arlington have developed a novel microwave-induced photodynamic therapy that can target deeply situated tumors. The treatment uses microwaves to activate photosensitive nanoparticles, producing tissue-heating effects that ultimately lead to cell death.
Kytai Nguyen, a nationally recognized professor of bioengineering at UTA, has overcome numerous challenges in her life and career. She was awarded the inaugural Embracing Challenge Award from Materials Today magazine for her perseverance and contributions to new knowledge in materials science and engineering.
Researchers at the University of Melbourne develop a novel approach to assemble nano-objects into complex architectures using polyphenol-coated building blocks. The technique enables the creation of 3D superstructures with enhanced chemical diversity and structural flexibility.
University of Illinois researchers have developed a method to quantify drug delivery from nanoparticles inside a cell, providing new insights into the efficacy of therapy and mechanisms underlying cellular uptake. This breakthrough could lead to more effective treatments by controlling and manipulating drug release.
The study found that silver nanoparticles' protein corona reduces their toxicity by forming silver sulfide nanocrystals, which are non-toxic. In the absence of a soft corona, Ag2S crystals form, precipitating toxic silver ions.
Researchers have demonstrated silicon nanoparticles that can manipulate and switch light, enabling ultrafast all-optical signal processing in optical communication systems. The nanoantennas can transmit, reflect, or scatter incident light in a specified direction, showing potential for high-speed data transmission.
Researchers developed nanoparticles that congregate at injury sites to form blood clots. These particles can cut bleeding time in half and reduce total blood loss, making them a potential game-changer for treating internal bleeding.
Researchers create ginger-derived nanoparticles that efficiently target the colon, reducing acute colitis, preventing chronic colitis, and enhancing intestinal repair. The particles retain key active constituents found naturally in ginger, showing promising therapeutic effects against inflammatory bowel disease and cancer.
Scientists have developed a neuron-targeting nanoparticle that can deliver RNA to damaged brain cells, reducing the impact of chronic conditions like depression and memory problems after TBI. The treatment showed promise in an animal model, with 80% reduction in protein associated with neuronal cell death.
Researchers create functional coatings with microorganism-resistance, self-cleaning and anti-reflecting properties. The new materials have potential for various applications, including seagoing vessels, mobile phone screens and spectacle lenses.
Physicists from UT Arlington are developing a multifunctional platform to integrate imaging and photo-induced cancer therapy in a single, portable device. The BIGLITE device aims to improve the efficacy and safety of photo-induced therapies by precisely killing cancer cells while sparing healthy ones.
Scientists at the University of Basel have created nanoparticles that can serve as efficient contrast agents for magnetic resonance imaging (MRI). These smart nanoparticles produce significantly more contrast than traditional contrast agents and respond to specific environments.
Researchers at Duke University have created gallium nanoparticles with a unique phase coexistence phenomenon, where the particle core is solid while the outer layer remains liquid. This discovery could lead to breakthroughs in nanotechnology applications, including ultraviolet sensors and molecular sensing devices.
Researchers at the University of Copenhagen have developed a method that kills cancer cells using nanoparticles and lasers. The treatment has been tested on mice and shown to be effective in destroying cancer tumors without causing major side effects.
Selecta Biosciences' synthetic vaccine particles have been shown to induce antigen-specific immune tolerance, mitigating the formation of anti-drug antibodies and improving the efficacy and safety profile of biologic drugs. The technology has potential applications in treating rare diseases, allergies, and autoimmune diseases.
University of Pennsylvania researchers have created nanoparticles that use the acidity of tooth decay to kill bacteria in dental plaque and prevent cavities. The treatment, which combines hydrogen peroxide with acid-sensitive nanoparticles, was shown to be highly effective at disrupting biofilms and killing bacteria.
Scientists from Kazan Federal University and Louisiana Tech University created a 'smart dress' for oil-degrading bacteria by coating them with magnetic nanoparticles. The modified bacteria retained their ability to form biofilms, crucial for attaching to oil droplets in natural environments.
Researchers created complex reconfigurable microrobots that can be manufactured with high throughput, mimicking the behavior of bacteria to deliver drugs or perform precise operations. The robots are soft, flexible, and motor-less, using electromagnetic fields and heat to control their movement.
Researchers investigate physical properties of nanoparticles to enhance therapeutic delivery, focusing on size as a critical factor. The study provides valuable insights for generating uniform nanoparticles with high yields and targeted cell uptake.
Researchers have discovered a 'smart' organic nanoparticle called PEARLs that uses heat and light to target and ablate tumours with greater precision. This innovation addresses two bottlenecks in photo-thermal therapy, enabling more effective treatment of cancer with minimal damage.
A new method for extracting, enriching and identifying chemical warfare agents from oils and organic liquids has been developed, using nanoparticles to capture the chemicals. The method can identify agents at low concentrations, overcomes challenges of detecting water-repellent agents, and has potential to save lives.
Researchers have discovered a new class of high thermal conductivity materials that can improve cooling for power electronics and other applications. The silicon dioxide nanoparticles, coated with ethylene glycol, can conduct heat at potentially higher efficiency than existing materials.
Researchers have developed a spinach-like, nanoparticle juice that can help doctors get a better look at the human gastrointestinal tract. The drink, made from chlorophyll-based nanoparticles, has shown promise in improving imaging techniques such as photoacoustic and PET imaging.