Researchers develop ultrastable RNA nanoparticles that can regulate cell function, bind to cancer cells, and deliver therapeutic molecules. The stable nanoparticles display favorable attributes, including polyvalent nature, modular design, thermodynamic stability, and chemical stability.
A new imaging technique has been developed to measure catalytical reactions of single nanoparticles and multiple particles printed in arrays. This allows researchers to determine the relationship between efficiency and nanoparticle size, shape, and composition, enabling fast screening of different nanoparticles.
Researchers at Rice University have discovered a nanoparticle that can restore balance to the brain's vascular system after an injury. The PEG-HCC nanoparticles immediately quench superoxide activity and allow the autoregulatory system to regain its balance, potentially treating mild brain trauma by preventing further damage.
Soybeans grown in soil contaminated with zinc oxide or cerium oxide nanoparticles show reduced crop yield and quality. The nanoparticles can accumulate in the plants, affecting food quality and potentially requiring increased use of synthetic fertilizers.
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Researchers at Case Western Reserve University developed synthetic platelets that double the survival rate of internal injury victims in the first hour after injection. The nanoparticles work by creating healthy clots and binding to natural platelets to form larger clots, reducing bleeding time.
Researchers have made progress toward a portable emergency treatment for stopping life-threatening internal bleeding. Synthetic platelets, artificial versions of blood's natural clotting particles, are being developed to quickly and efficiently form clots at internal wounds, increasing survival rates in laboratory tests.
Researchers will develop nanocomposites for medical implants that break down safely, replacing metal implants in bone surgery. The project tackles challenges in nanoparticle production, dispersion, degradation, and scaling up manufacture.
Researchers have developed a simple, low-cost method to synthesize silver nanoparticles using strawberry tree leaf extract. The technique allows for control over nanoparticle size and geometry, resulting in stable particles that remain effective for up to 6 months.
A team of scientists aims to create novel materials that change shape in response to external stimuli like heat or light. The researchers will use high-throughput techniques to identify components that can be combined to produce interesting effects.
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Researchers found that silver nanoparticles are less toxic to bacteria than their released ions. The team's study suggests that controlling the rate of ion release can enhance antibacterial properties and mitigate environmental impacts. They also discovered hormesis, where low doses of silver ions stimulate bacterial growth.
Researchers at Brigham and Women's Hospital have developed a new approach to cancer treatment using supramolecular nanochemistry. The innovative nanoparticles significantly enhanced antitumor activity while reducing toxicity in breast and ovarian cancer models.
Researchers used electron holography to capture images of electric fields created by ferroelectric materials' atomic displacement. This technique could guide scaling up these materials and ushering in a new generation of advanced electronics.
Scientists at Johannes Gutenberg University Mainz discovered that vanadium pentoxide nanoparticles can inhibit the growth of barnacles, bacteria, and algae on surfaces in contact with water. This could lead to the development of new protective coatings that are less damaging to the environment than current ship coatings.
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Researchers at Brown University found that selenium nanoparticles can reduce Staphylococcus aureus bacteria on implant materials by up to 90%. The coating is more effective than current silver-based alternatives, which are less biocompatible and expensive.
Researchers have developed a method to produce silver nanoparticles using pomegranate peel as a reducing agent, avoiding the use of harsh chemicals and industrial solvents. The process produces nanoparticles with a diameter of 5 nanometers and has potential applications in various fields.
Researchers at Notre Dame have engineered nanoparticles that can target cancer cells in bone marrow, reducing the development of drug resistance and allowing for more effective treatment. The particles also reduce toxic side effects on healthy organs, promising a new approach to multiple myeloma therapy.
Research by Trinity College Dublin scientists establishes a clear link between nanoparticles and autoimmune diseases like rheumatoid arthritis. Exposure to nanoparticles can trigger the transformation of amino acids, leading to inflammation and tissue damage.
The NIH has awarded $400,000 to Arizona State University's Kevin Bennett to develop a non-invasive method for detecting nephritis, a common form of kidney disease. The new technology uses magnetic resonance imaging and magnetic nanoparticles to extract information about the kidney's function and location.
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Researchers at the University of Notre Dame have developed a new sensor that can detect organic contaminants in water at very low concentrations. The sensor uses silver nanoparticles and graphene oxide films, allowing for side-selective deposition of metal ions.
A team of researchers has created nanoparticles made from DNA and RNA that can deliver snippets of RNA directly to tumors, turning off genes expressed in cancer cells. The new particles pose less risk of side effects and offer better targeting due to their biodegradable nature.
A new type of biosensor, known as a biochemiresistor, has been developed by a UNSW-led team to detect tiny traces of contaminants in liquids in just 40 minutes. The sensor can detect one-billionth of a gram of the veterinary antibiotic enrofloxacin in milk with high sensitivity and speed.
Researchers developed coatings that use nanoparticles to interact with sunlight and break down pollutants like nitrogen oxides, hydrocarbons, and carbon monoxides. The coating is thin, adaptable, and durable, making it suitable for construction materials.
Researchers at Berkeley Lab directly observed the critical step of oriented attachment in nanocrystal growth, enabling a better understanding of forces driving this phenomenon. This breakthrough has potential applications in synthesizing new biomimetic materials and improving environmental restoration efforts.
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Researchers at Berkeley Lab observed nanoparticles forming winding polycrystalline chains that align and attach end-to-end to form nanorods with controlled length-to-thickness ratios. This process suggests a new understanding of how nano-sized particles assemble into hierarchical structures.
The Iowa State team has successfully delivered functional protein and DNA into plant cells using custom-built nanoparticles, opening up opportunities for targeted genome editing in crop plants. This achievement marks a significant advancement toward delivering proteins and enzymes to both animal and plant cells.
Researchers studied adhesion of E. coli to silver- and copper-coated porous clay ceramic surfaces, with silver nanoparticles showing highest affinity for bacteria. Copper may be a less expensive alternative to colloidal silver as a disinfectant coating.
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Researchers at Northwestern University have developed a new, all-solid-state solar cell that exceeds the performance of traditional Grätzel cells. The device achieves an impressive conversion efficiency of approximately 10.2 percent and is stable over time, addressing key limitations of current solar technology.
The new handbook provides a common scientific basis for nanoparticle testing, standardizing procedures and analytical methods. It aims to improve the comparability of research results and address concerns about nanoparticle toxicity.
Researchers aim to develop commercially viable and scalable method for producing nanocomposites, potentially leading to faster production of electronic devices such as transistors and solar cells. The new approach combines molecular beam epitaxy and inert gas condensation to increase material production speed.
Scientists have developed a new technique that allows for the mapping of nanoparticle atomic structures using transmission electron microscopes, removing barriers to widespread use. The method produces highly similar results with x-ray synchrotron data and has potential applications in energy, medicine, and materials science.
Scientists have extended the trapped particles' useful life more than tenfold by using a refined technique for trapping and manipulating nanoparticles. The new approach, which involves a control and feedback system that nudges the nanoparticle only when needed, increases the lifetime of the particle while reducing its tendency to wander.
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A UNC study successfully delivers therapeutic doses of a cancer drug using nanoparticle carriers, overcoming pharmacologic challenges that led to its abandonment. The study demonstrates improved efficacy and reduced toxicity for the abandoned drug.
Researchers at McLean Hospital have developed a new category of nanoparticles that can non-invasively cross the blood-brain barrier, transporting various types of drugs. These nanoparticles also outperform existing MRI contrast agents, offering a significant improvement in imaging performance and reduced gadolinium toxicity.
Engineers at Stanford University have developed a novel method to decorate nanowires with nanoparticles, increasing surface area and altering surface chemistry. This technique may lead to improved lithium-ion batteries, more efficient thin-film solar cells and enhanced catalysts.
Researchers have found evidence that engineered nanoparticles can accumulate in plants and cause DNA damage. The study tested cupric oxide nanoparticles on radish and ryegrass, finding increased DNA base lesions and cellular uptake of copper in plant root cells.
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Researchers at Stanford University developed nanoparticles that can be imaged three ways at once and highlighted brain tumors, precisely delineating their boundaries. The technique could improve prognosis for patients with glioblastomas, the most aggressive form of brain tumor.
Researchers at MIT have developed hybrid copper-gold nanoparticles that can convert carbon dioxide into hydrocarbon fuels with significantly less energy than pure copper. The tiny particles, engineered to increase surface area and stability, have the potential to greatly reduce greenhouse gas emissions from powerplants.
A team of scientists has developed porous carbon nanoparticles that utilize sulfur molecules to achieve high efficiency in lithium-sulfur batteries. The sulfur can absorb two lithium ions per sulfur atom, making it an excellent energy storage material.
Northwestern University scientists develop gold nanostars that target cancer cells' nucleus, releasing a killing drug. The nanoparticles are attracted by a protein on the surface and change shape after drug release, causing cell death.
Researchers have developed environmentally-friendly iron-based nanoparticle catalysts that work as well as expensive metal-based catalysts. This breakthrough reduces the need for toxic and expensive organic ligands, making industrial syntheses more cost-effective.
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Researchers used nanoparticles and magnetic fields to kill head and neck cancerous cells in mice without harming healthy cells. The treatment induced hyperthermia, raising the body temperature of only the concentrated nanoparticles within the tumor site.
Researchers at Stanford University have directly observed plasmon resonances in individual metal particles measuring down to one nanometer in diameter. This discovery could lead to advancements in catalytic processes, cancer research and treatment, and quantum computing.
Researchers have developed nanoparticles of chitosan, a natural polysaccharide from shrimp shells, with effective antimicrobial activity against Staphylococcus saprophyticus and Escherichia coli. These nanoparticles also stimulate skin cell growth, enhancing wound healing and potentially leading to anti-aging benefits.
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Researchers developed nanoparticles called nanopills to release proteins with therapeutic effects, successfully recovering activity in 'sick' mammalian cells. The technology has been licensed and is being developed by biotech firm Janus Developments.
A recent study by the Norwegian Institute of Public Health found that silver nanoparticles can suppress cellular growth and multiplication, causing cell death depending on concentration and duration of exposure. Titanium dioxide nanoparticles also caused DNA damage but with weaker effects.
Researchers at Binghamton University found that nanoparticles affect the absorption of nutrients like iron, causing disruptions to intestinal function. Chronic exposure leads to changes in intestinal villi size, increasing iron absorption rates.
Scientists discovered that silver nanoparticles effectively kill hard-to-treat yeast infections, including oral thrush and dental stomatitis. The nanoparticles' stability in liquid medium makes them a potential strategy for developing alternative treatments.
Researchers at NIST have created a method to directly correlate particle size, shape, and agglomeration with redox chemical properties of nanoparticles. This allows for the observation of structural changes in nanoparticles during important chemical reactions.
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University of Oregon researchers developed new measuring techniques that monitor nanoparticle growth, reducing waste and environmental risks. By using green chemistry approaches, they improved efficiency and stability of nanoparticles.
Research reveals that plastic nanoparticles impact fish feeding behavior and metabolic parameters, including weight loss and cholesterol levels. The findings have implications for assessing nanoparticle risks in aquatic ecosystems.
Researchers developed a three-dimensional living tissue model to study brain tumors and therapeutics, confirming iron-oxide nanoparticles can deliver tumstatin to blood vessels surrounding gliomas. The model allows for testing of agent characteristics in a realistic environment.
Researchers warn that billions of engineered nanoparticles are ingested daily, potentially blocking iron absorption and causing subtle effects on health. The study used chickens as a model to simulate human exposure and found changes in intestinal cell structures.
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Researchers used 3D computer simulations to study the diffusional behavior of nanoparticles on surfaces. They found that ordered nanorods can facilitate faster diffusion than disordered ones, with channels between rods enabling particles to speed through.
Researchers developed a nanoparticle microfluidic color device for rapid detection of acute sepsis and other biomarkers, offering improved accuracy and speed in medical diagnostics. The device boasts high sensitivity and can detect minute quantities of biomolecules, making it a promising solution for point-of-care diagnostics.
Scientists at Duke University Medical Center created nanoparticles that target lymph nodes to greatly enhance vaccine responses. The particles mimic natural mast cell granules and provide a timed release of inflammatory mediators, stimulating effective immune reactions in mice vaccinated with the influenza A virus.
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A team of researchers from Pitt and UMass proposes a 'repair-and-go' approach to fix malfunctions caused by small-surface cracks on any digital device. This method uses nanoparticles and droplets of oil to repair defects on-site, potentially extending the device's lifetime.
Researchers have successfully penetrated fruit flies' brains with ORMOSIL nanoparticles, which hold promise as a potential vehicle for targeted drug delivery. The particles can be filled with helpful chemical compounds or gene therapies to target neurodegenerative disorders like Alzheimer's disease.
A team of researchers at the University of Notre Dame has created a one-coat solar paint that can be applied to any conductive surface without special equipment. The paint uses semiconducting nanoparticles to produce electricity, offering a potential solution for inexpensive and efficient energy production.
Researchers developed a method to characterize the optical properties of ZnO nanoparticles, allowing them to assess their safety in sunscreen. The study found that nanoparticles did not penetrate beneath the stratum corneum, the topmost layer of skin, after being applied and washed off.
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A recent study by Marshall University researchers discovered that nanoparticles of cerium oxide, commonly used in diesel fuels, can travel from the lungs to the liver and cause damage. The study found a dose-dependent increase in cerium levels in the liver, associated with liver enzyme elevations and histological evidence of liver damage.