Research on engineered particles at the nanoscale. Covers hyperspectral imaging, nanoparticle cancer therapy, gene-editing delivery, and heat-beating materials.
Researchers at Penn State University have invented a method using magnetic fields to purify hybrid nanoparticles, which are composed of two or more kinds of materials. This technique will help improve drug-delivery systems, drug-targeting technologies, medical-imaging technologies, and electronic information-storage devices.
The discovery reveals changes in silicon's mechanical response with decreasing size, driving unexpected deformation mechanisms. This finding provides a basis for understanding the onset of plasticity in nanovolumes, benefiting nano-device design.
New research from Brown University finds that nickel nanoparticles can activate a cellular pathway that contributes to cancer in human lung cells. The study shows that smaller nanoscale particles are more harmful and potentially cancer-causing than larger microscale particles.
Researchers at the University of Michigan have discovered a generic mechanism for creating near-perfect nanoparticles that assemble into uniform structures. The breakthrough enables the formation of clusters with desirable properties, such as size, shape, and electrical conductivity.
Researchers at Syracuse University have developed tunable nano-suspensions capable of capturing specific wavelengths of sunlight, paving the way for improved solar energy efficiency and smart glass technologies. By manipulating the composition of the suspension, scientists can achieve optimal optical properties.
Scientists have developed a new heart model to investigate the effects of artificial nanoparticles on cardiac function. Exposure to certain types of nanoparticles led to increased heart rates, cardiac arrhythmia, and modified ECG values typical of heart disease.
Scientists have successfully used camel blood-derived nanobodies to target and kill cancer cells expressing specific markers. The approach involves attaching the nanobodies to nanoparticles that deliver a killer gene, preventing non-specific cell killing and improving safety.
Researchers have found that human Sertoli cells can proliferate in vitro and retain their functionality, making them suitable for therapeutic applications. The cells have also been successfully used as delivery systems for therapeutics in the deep lung areas, potentially providing an effective treatment alternative.
Researchers have developed a novel gene therapy system using nanoparticles that can be freeze-dried and stored for up to three months. The technology shows promise in treating brain cancer with high efficacy and minimal risk of complications, offering a potential alternative to traditional therapies.
Researchers at UC San Diego developed a method to disguise nanoparticles as red blood cells, allowing them to evade the immune system and deliver cancer-fighting drugs directly to tumors. This breakthrough could lead to more personalized drug delivery, reducing the risk of immune response.
Researchers create the world's first three-dimensional plasmon rulers, capable of measuring spatial changes in macrmolecular systems, providing a new tool for understanding critical biological events. The 3D plasmon rulers enable scientists to retrieve complete spatial configuration and track dynamic evolution of complex processes.
Researchers have developed Cornell Dots, ultra-small particles that can light up cancer cells. The technology enables visualization during surgical treatment and shows invasive or metastatic spread to lymph nodes and distant organs.
The new nanoparticles can carry hundreds of light-sensitive molecules, creating more reactive oxygen species from the same amount of light. This design allows the nanoparticles to penetrate easily into tumors and deliver targeted damage to cancer cells.
A recent literature review analyzed nearly 100 scientific articles on the effects of nanoparticles on edible plants. The study found that nanoparticle uptake and build-up vary depending on plant type, nanoparticle size, and chemical composition, highlighting a need for further research in nanoecotoxicology.
Physicists at the University of Michigan have successfully created 3D arrays of optically induced crystals using laser beams. The technique allows for the formation of crystalline structures without the need for X-ray crystallography, which is commonly used to analyze biological molecules.
Researchers found that carbon black nanoparticles activated a double source of inflammation in the lungs, causing immune cells to die and leading to a secondary inflammatory response. The study suggests environmental exposures to diesel exhaust or printer ink could contribute to lung inflammation.
Researchers at Berkeley Lab demonstrated antenna-enhanced gas sensing at the single particle level using a palladium nanoparticle on a gold nanoantenna. The technique amplifies plasmonic sensing signals, eliminating statistical characteristics and offering noninvasive, biocompatible applications.
Researchers create engineered mesoporous silica nanoparticles that improve drug delivery to tumors, increasing particle retention by up to 10% and reducing systemic side effects. The optimized platform achieves significant increases in doxorubicin delivery, inducing tumor shrinkage and apoptosis while improving safety profiles.
MIT scientists have designed a new type of nanoparticle that can target nearly any type of tumor by utilizing the acidic environment shared by most cancers. The particles are designed to break down in the slightly more acidic environment near a tumor, revealing another layer that can penetrate individual cells.
Scientists have developed a new imaging agent using tantalum oxide nanoparticles, which stays in the body long enough to image multiple organs. The material is inexpensive and has shown promising results in laboratory tests, potentially overcoming limitations of existing imaging agents.
University of Cincinnati researchers have successfully produced large RNA nanoparticles using a bipartite approach, overcoming challenges in industry-scale production. The nanoparticles, containing small interfering RNA, show a half-life of between five and 10 hours in animal models, are non-toxic and produce no immune response.
Engineered gold nanoparticles have been shown to be non-toxic when administered by two alternative routes in mice, suggesting they may be safe for human use. The particles are designed to detect cancer-lesion sites with high sensitivity and could lead to early disease detection.
Researchers have created nanoparticles that can store large amounts of drugs, allowing for a millionfold increase in efficiency over comparable methods. The 'protocells' can target specific cancer cells while restricting toxic chemotherapy drugs from leaking into the system, mitigating side effects.
A new study from North Carolina State University finds that the general public perceives nanoparticles as a relatively low risk, with 60% of respondents viewing them as posing only a slight health risk or none at all. The study compared public perceptions of nanoparticle risks to other environmental and health safety risks.
A new study reveals that alumina nanoparticles enhance biodiesel combustion, increasing fuel efficiency while decreasing nitrogen oxide and carbon monoxide emissions. Researchers are now exploring other types of nanoparticles for potential engine lubrication and cooling systems.
A new study reveals that exposure to vehicle pollution can cause significant brain damage in mice, including signs of memory loss and Alzheimer's disease. The tiny particles from burning fossil fuels and weathered car parts are too small for filters to trap, raising concerns about human health.
Researchers at Queen's University discovered that silver nanoparticles can be highly toxic to microbial communities in Arctic soil, compromising the ecosystem's ability to fix nitrogen. The study's findings highlight the need for further consideration of innovation's impact on the environment.
Researchers have mixed nanoparticles into heat-transfer oils to increase the efficiency of solar collectors. This could lead to significant revenue gains for solar power plants. The use of nanoparticles also has potential applications in filtering out pollutants from coal power plants.
Scientists at Brigham and Women's Hospital have developed nanoparticles containing calcium that can capture nickel efficiently without penetrating the skin. This breakthrough could provide a new strategy for preventing nickel-induced contact dermatitis, affecting millions worldwide.
Researchers have developed nanoparticles loaded with siRNA to silence cancer-promoting genes in ovarian cancer, selectively shrinking or destroying tumors. The nanoparticles use high-density lipoprotein (HDL) as a delivery vehicle, which is taken up by cancer cells and not healthy tissue.
Researchers at North Carolina State University have successfully created ordered layers of nanoparticles using spincasting, a technique that utilizes centrifugal force to distribute liquids onto solid substrates. This approach has promising results for the creation of materials with various uses, from optics to electronics.
Researchers have created an organic nanoparticle that uses sound and heat to target tumors, offering a promising new approach to cancer treatment. The nanoparticle's ability to absorb light and accumulate in tumors makes it ideal for photothermal therapy.
Researchers at North Carolina State University have developed a new method for creating uniform carbon nanofibers, which could enable precise scientific measurement tools and medical imaging devices. The technique uses nickel nanoparticles coated with ligand shells to grow carbon nanofibers of specific sizes.
Researchers developed a new 3D printing method that enables the creation of electrically small antennas with improved performance metrics. The technique uses metallic nanoparticle inks and can be applied to various surfaces, including hemispherical substrates.
The new instrument, developed at UCSB, can detect nanoparticles in fluid at rates of up to half a million particles per second. It measures the volume of each nanoparticle for rapid and precise size analysis of complex mixtures.
Researchers have discovered that the coating of nanoparticle surfaces significantly influences immune activation, allowing for more targeted treatment of diseases. The study shows that designing polymers in various ways can drastically change the body's immune response.
McGill researchers develop a cheap, portable paper-based filter to produce clean drinking water in emergency situations. The filter, coated with silver nanoparticles, is able to kill nearly all bacteria and produce water that meets EPA standards.
Scientists at Emory Vaccine Center developed nanoparticles that mimic viruses to induce lifelong immunity in mice. The particles, made of biodegradable polymers, activate two different parts of the innate immune system and can be used with material from various bacteria or viruses.
Scientists have designed a new type of nanoparticle that can deliver synthetic versions of proteins normally produced by viruses, eliciting a strong immune response comparable to live virus vaccines. The nanoparticles consist of concentric fatty spheres that can be used to develop vaccines against cancer and infectious diseases.
Researchers at Albert Einstein College of Medicine have developed nanoparticles containing nitric oxide that improve survival after life-threatening blood loss in hamsters. The therapy maintains blood circulation and protects vital organs by increasing levels of NO gas, which relaxes blood vessels and regulates blood pressure.
Researchers designed nanoparticles by engineering the support structure, exposing stable crystal faces for enhanced selectivity and yield in catalytic reactions. The discovery could lead to better catalysts with a significant impact.
Researchers Marta Rossell and Rolf Erni developed a new technique to study the 3D structure of nanoparticles, enabling the determination of their atomic arrangement. This breakthrough could improve understanding of nanoparticle properties, reactivity, and toxicity.
The European Commission Joint Research Centre has developed the world's first certified reference material for nanoparticle size analysis. The material provides a stable benchmark for reliable hazard assessments and process quality control, promoting market confidence and innovation.
Scientists have developed a new food packaging material called 'killer paper' with silver nanoparticles that fights bacteria causing spoilage. The coating is effective against E. coli and S. aureus, killing bacteria in just three hours.
Researchers found excessive calcification of fetal membranes may lead to preterm premature rupture of the membranes (PPROM) and preterm birth. Lower fetuin levels in amniotic fluid were linked to women at risk of PPROM.
Researchers at the University of California - Davis have developed a new approach to solar cells by constructing them from extremely small nanoparticles. The team aims to achieve an efficiency of 42-65%, surpassing the current theoretical maximum of 31%.
Researchers at NIST developed a method to produce nanoparticle clusters in controlled sizes, stable over time. The study found that larger clusters may be less toxic to human cells due to slower dissolution rates.
New nanoparticles designed to target fibrin in blood clots can be seen with a new type of CT scanner, providing early detection and potential treatment options for heart attacks. This technology has the potential to save lives by quickly identifying unstable plaque and guiding targeted treatments.
Researchers have shown that nanosilver is not a new discovery but has been used for over 100 years to prevent bacterial growth. Nanoparticles have different properties than larger particles, making them more reactive and toxic to bacteria.
Magnetic nanoparticles can detect cervical cancer by trapping antibodies, offering earlier screening and treatment. Similarly, these nanoparticles can detect E. coli infections at lower bacterial cell counts, halting disease spread faster.
Researchers at Georgia Tech have developed a new treatment system that uses magnetic nanoparticles to capture free-floating cancer cells, slowing tumor progression in humans. The system aims to reduce chemotherapy side effects by removing the primary source of metastasis.
Massachusetts General Hospital researchers developed nanoparticles containing keratinocyte growth factor that accelerate wound healing in diabetic mice. The fusion protein retained wound-healing properties and efficiently delivered growth factors to deeper tissues.
Scientists have developed a new material consisting of copper-coated silica nanoparticles that can eliminate unpleasant odors. These nanoparticles are up to twice as effective as the current gold standard, activated carbon, in removing foul-smelling substances like ethyl mercaptan.
Researchers at Purdue University have developed a tiny slide-sized model of the female breast, dubbed 'breast on-a-chip,' to test nanomedical approaches for detecting and treating breast cancer. The model mimics the branching mammary duct system where most cancers begin.
Scientists have developed a method to create stable three-dimensional RNA nanoparticles by modifying their chemical structure, making them resistant to RNase degradation. This breakthrough has significant implications for the use of RNA in nanotechnology applications, including targeted therapies for cancer and viral infections.
Scientists have developed a new food packaging material that uses silver nanoparticles to fight bacteria and extend shelf life. The material has been shown to be effective against E. coli and S. aureus, two common causes of bacterial food poisoning.
Researchers at the University of Central Florida have developed a technique to detect cholera toxin using a complex sugar and nanoparticles. The method could provide faster and less expensive results than current detection methods, enabling relief workers to restrict access to contaminated sources.
Researchers have created a new type of nanoparticle called nanodisks, which can carry genetic material and enter cells quickly without losing its potency. These nanodisks offer a promising alternative to traditional gene therapy vectors, potentially improving therapeutic outcomes.
Researchers have developed nanoparticles that deliver the cancer drug cisplatin more effectively and safely, reducing its potentially severe side effects. The new particles successfully shrink tumors in mice using only one-third of the conventional dose.
A study by the University of Kentucky found that earthworms can absorb copper nanoparticles present in soil, raising concerns about potential exposure to humans and animals. The research has significant implications for understanding the interactions of nanomaterials in the environment.