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Better transplants for better joints: A closer look at micromechanical mismatch influences in cartilage regeneration

A team of scientists from TIBI, UIC, and POSTECH has elucidated key points on how cartilage generation is facilitated and alternative bone formation can be avoided. They found optimal conditions for better cartilage regeneration while reducing excessive cartilage formation using human mesenchymal stem cells.

SourceTerasaki Institute for Biomedical Innovation·JournalMatter·TypeExperimental study·DateDec 21, 2022

Re-spun silkworm silk is 70% stronger than spider silk

Scientists at Tianjin University have discovered a way to make silkworm silk 70% stronger than spider silk by removing its sticky outer layer and manually spinning it. This breakthrough could lead to the production of profitable high-performance artificial silks, revolutionizing industries such as biomedicine and tissue regeneration.

SourceCell Press·JournalMatter·TypeExperimental study·DateOct 6, 2022

T cells use force to destroy cancer cells

Researchers at UNSW Sydney discovered that T cells use mechanical forces to propel lytic granules towards cancer cell membranes. The study found that the shape of the target membrane plays a crucial role in T cell-mediated cancer cell killing, with a bias towards outwardly curved membranes.

SourceUniversity of New South Wales·JournalDevelopmental Cell·TypeExperimental study·DateSep 15, 2022

Muscle mechanics: Improving sports performance with muscle mechanical properties

A recent study investigated the relationship between passive muscle mechanical properties and dynamic performance in athletes. The research found a positive correlation between the shear modulus of the vastus lateralis muscle and performance outcomes during high-speed activities, suggesting that passive muscle properties are essential ...

SourceShizuoka Sangyo University - Iwata Campus·JournalEuropean Journal of Sport Science·TypeObservational study·DateAug 3, 2022

CNIC scientists discover a new mechanism involved in the modulation of heart muscle elasticity

Researchers have identified a new mechanism involving the oxidation of cysteines in titin protein that modulates cardiac stiffness and dynamics. This discovery sheds light on how the heart adapts to various situations and responds to oxidative balance disorders.

SourceCentro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)·JournalRedox Biology·TypeExperimental study·DateApr 27, 2022

NIST researchers link cutting-edge gravity research to safer operation of construction cranes

Researchers from NIST have developed a mathematical model that predicts the strength and timing of changes in velocity required for crane operators to apply when transporting heavy loads. This equation can be applied to various situations, including moving a load with initial rest and large distances.

SourceNational Institute of Standards and Technology (NIST)·JournalAmerican Journal of Physics·TypeComputational simulation/modeling·DateFeb 18, 2022

Improving strength, stretchiness and adhesion in hydrogels for wound healing

Researchers from Terasaki Institute for Biomedical Innovation develop methods to enhance mechanical properties of hydrogels, including toughness, stretchiness, and adhesive strength. By introducing dopamine and alkaline conditions, they create gel-like materials with improved biocompatibility and regenerative capabilities.

SourceTerasaki Institute for Biomedical Innovation·JournalACS Applied Materials & Interfaces·TypeExperimental study·DateAug 30, 2021

Alginic acid improves artificial bones, study shows

A study published in the Journal of Materials Science: Materials in Medicine found that alginic acid improves artificial bones by increasing porosity, compressive strength, and setting time. The addition of alginic acid to calcium phosphate cement enhances its mechanical properties, allowing for more effective bone replacement.

SourceOsaka City University·JournalJournal of Materials Science Materials in Medicine·TypeNews article·DateAug 11, 2021

Like an artificial nervous system

An interdisciplinary research team at Kiel University has produced a highly conductive hydrogel that retains its elasticity, suitable for medical implants. The innovative production method uses graphene to achieve high electrical conductivity while maintaining the original mechanical properties.

SourceKiel University·JournalNano Letters·DateMar 18, 2021

New imaging technology could help predict heart attacks

Researchers developed a new intravascular imaging technique, ILSI, which can detect unstable coronary plaques. The technique provides a direct assessment of mechanical stability, allowing for early detection and treatment of high-risk vulnerable plaques.

SourceOptica·JournalBiomedical Optics Express·DateMar 16, 2021

Scientists shed new light on pollen tube growth in plants

Researchers discovered that the KATANIN enzyme plays a crucial role in moderating mechanical properties of papilla cell walls, allowing correct pollen tube orientation and successful fertilization. This finding suggests KATANIN's potential role in the success of flowering plants on Earth.

SourceeLife·DateSep 1, 2020

New view on how tissues flow in the embryo

Scientists at Columbia University developed a new method to analyze cell shapes in fruit fly embryos, revealing that tissues can behave like fluids during rapid changes. By combining experimental studies with theoretical modeling, the team found that anisotropy plays a crucial role in predicting tissue flow and elongation.

SourceColumbia University School of Engineering and Applied Science·JournalProceedings of the National Academy of Sciences·DateMay 28, 2020

Physics can show us the inside of tumors

Researchers used noncontact imaging to differentiate malignant cells and monitor treatment effectiveness, revealing mechanical properties of tumors that influence disease progression. This technique may lead to personalized therapies and more effective treatments.

SourceCNRS·JournalPhysical Review Letters·DateJan 8, 2019

Scientists squeeze nanocrystals in a liquid droplet into a solid-like state and back again

Researchers at Lawrence Berkeley National Laboratory have discovered a way to transform a liquid-like state into a solid-like state and back again by introducing a chemical compound. The study has implications for developing all-liquid electronics and interacting with cells, and could lead to new ways of controlling nanoscale elements.

SourceDOE/Lawrence Berkeley National Laboratory·JournalScience Advances·DateAug 8, 2018

A more complete picture of the nano world

Researchers have developed a new method, peak force infrared (PFIR) microscopy, which allows for simultaneous chemical and mechanical imaging of materials at the nanoscale. This technique enables the analysis of material properties at various places, providing insights into heterogeneous and biological materials.

SourceLehigh University·JournalScience Advances·DateAug 23, 2017

POSTECH team creates a more durable protein hydrogel based on elastic silk-like protein

Researchers created a mechanically durable hydrogel using an elastic silk-like protein called aneroin, which has improved mechanical properties compared to collagen and silkworm silk. The aneroin hydrogel provided an adequate environment for cell growth, proliferating mammalian cells with healthy morphology.