Articles tagged with High Resolution Imaging
A study published in Molecular Psychiatry found that about 65% of patients who developed psychosis after age 40 showed abnormal tau buildup, compared to 15% of healthy older controls. The findings suggest diverse tau-related brain changes may be involved in late-onset psychosis.
Physicists have developed a method to visualize three-dimensional wavefunctions of molecules, enabling the study of molecular interactions. The technique, which uses a table-top soft-X-ray laser and powerful computer algorithms, allows for the imaging of features smaller than atomic scales.
Researchers have developed a high-resolution light-sheet imaging system that can capture seizure propagation in the brain of larval zebrafish in 3D. The system allows for rapid volumetric imaging with real-time correction of aberrations, providing new insights into seizure mechanisms and brain function.
The OU College of Medicine has received a $10.7 million NIH grant to study how cells sense their environment and respond to diseases that occur when this process malfunctions.
Researchers developed gallium-doped zinc oxide nanosheets that can detect red, green, and blue light while remaining nearly transparent. These nanosheets enabled the detection of full-color images with half the error of conventional cameras, making them suitable for demanding environments like space hardware and automotive systems.
Researchers at the University of Pittsburgh developed a new imaging technique to visualize nerve patterns in densely innervated joints, such as the temporomandibular joint (TMJ). The c-Clear method produces a three-dimensional map of nerves with minimal tissue damage, allowing for better understanding of disorders like TMDs and TMJ pain.
Researchers have created a special flat lens that shapes light into an optical needle, allowing for deeper imaging while maintaining high resolution. This innovation combines with optical coherence tomography (OCT) to extend imaging depth by a factor of nine without requiring a complicated redesign.
The EMBL Grenoble team created two systems, EasyGrid and EasyGrid Control, to automate sample preparation for various techniques. These platforms improve the quality of samples by reducing manual handling and ensuring reproducibility, enabling faster optimization and better results.
FireANTs, an open-source algorithm, combines AI optimization and geometry to quickly match complex medical images. The new method can accomplish what took weeks in minutes, detecting subtle changes that signal disease or cognitive decline, making it practical for clinical practice.
Researchers are developing an AI assistant to analyze petabytes of imaging data from high-resolution microscopes, which can track cells and molecular interactions in real-time. The goal is to help biologists understand complex biological systems and make new discoveries.
A new approach enables computers and machines to capture images at higher resolution and faster speed, making it impervious to reflective surfaces. The technology uses a virtual screen created by repurposing the surroundings of specular objects.
Researchers developed multiplexed MRI technology, enabling simultaneous imaging of signals from multiple molecules in the brain. The technology provides a comprehensive view of the brain's structure, physiology, and molecular processes, allowing for more precise diagnosis and individualized treatment planning.
Researchers discovered that interictal epileptiform discharges (IEDs) occur in a predictable pattern, unfolding sequentially in individual neurons. Nearly 80% of IED-involving neurons are also involved in language and perception, suggesting the brain blips can derail cognition.
Scientists successfully built the smallest X-ray interferometer to measure how X-rays interact with atomic nuclei. This breakthrough technology enables precise measurement of X-ray refraction and provides new avenues for research.
Salk scientists and collaborators advance visualization technology using visible-spectrum antigen-stabilizable fluorescent nanobodies (VIS-Fbs), reducing background fluorescence by up to a hundredfold. The new probe enables high spatial and temporal precision, allowing for real-time tracking of dynamic changes in living models.
A new study co-led by OHSU scientist Catherine Galbraith introduces a series of fluorescent dyes that enable the observation of dynamic biological processes in living cells. These tools allow scientists to study cancer-related processes, such as DNA packaging and gene expression, in real-time.
Twelve life science startups have been selected for the Innovation AveNEW program at SLAS Europe 2026. The companies will showcase their products and services in a specially designated area on the exhibition floor, engaging with purchasing influencers and decision-makers from over 40 countries.
Scientists at the University of Warwick have developed a fully fibre-coupled terahertz imaging system that significantly improves the speed and clinical practicality of terahertz imaging. The system delivers near video-rate imaging with high spatial resolution, opening up possibilities for rapid, non-invasive diagnosis.
A new database of 3D ant models, Antscan, provides high-resolution micro-CT scans of 800 different ant species, revolutionizing the study of organismal shape and form. The database facilitates large-scale digitization of small organisms, enabling scientists to better model ant movement and study locomotion.
Researchers developed a dedicated microfluidics system to overcome limitations of existing methods in multiplexed super-resolution microscopy. The new platform precisely injects and removes solutions, allowing for high-quality imaging of proteins, specialized structures, and complex interactions within cells.
Researchers at TU Wien combined two microscopy techniques to create a method for measuring the optical properties of biological samples with high precision. By analyzing the size of fluorescent molecules' light disks, they can determine the refractive index of materials and reconstruct three-dimensional images.
Researchers at IIT develop optical microscopy technique that combines polarization and dark-field microscopy to observe cells with high contrast, preserving their natural conditions. The next step involves using AI to enrich images with molecular information related to diseases.
Researchers develop a new fabrication approach to produce multi-element optical components for super-resolution imaging, enabling customized imaging systems. The technique uses consumer-grade 3D printers and low-cost materials, producing high-performance lenses at a cost of less than $1 each.
The new system can reveal early cancers, lung disease, hidden material defects and changes in porosity without multiple exposures or complex mechanical movement. This method produces low-dose and faster images, lowering patients' radiation dose and making clinical translation feasible.
Duke engineers built an AI optical microscope that can analyze 2D materials with up to 99.4% accuracy, identifying layer regions and subtle defects. The system, ATOMIC, leverages publicly available AI foundation models to speed up the process, requiring no specialized training data.
A new study using next-generation imaging technology discovered that when the brain is falling asleep, it shows a coordinated shift in activity. Areas involved in thinking, memory, and daydreaming quiet down and use less energy during NREM sleep.
The UT Health San Antonio Center for Brain Health will unveil a 7-Tesla Terra.X MRI system, providing ultra-high-resolution brain images for diagnosing and studying conditions like dementia and Parkinson's. The technology expands what is possible in research and discovery.
Scientists have tracked 1039 dust devils to reveal how they lift dust into the air and sweep around Mars' surface. The study found wind speeds of up to 44 m/s, faster than previously measured with rovers on the ground, and improved our understanding of Martian weather patterns.
Researchers at the University of Arizona are developing a new optical technology that can image deep into biological tissues without invasive procedures. This approach aims to overcome current challenges in skin cancer imaging, allowing for earlier detection, precise evaluation, and real-time monitoring of treatment response.
Researchers from UCL and Imperial College London have discovered how life-saving antibiotics called polymyxins target the outer layer of Gram-negative bacteria. By triggering the production and shedding of this armor, polymyxins create gaps in the cell's defenses, allowing the antibiotic to enter and kill the bacteria.
Researchers developed MoBluRF, a two-stage motion deblurring method for NeRFs, achieving high-quality 3D reconstructions from ordinary blurry videos. The framework outperforms state-of-the-art methods and is robust against varying degrees of blur, enabling smartphones to produce sharper and more immersive content.
The PANORAMA microscope overcomes challenges of traditional microscopes by capturing submicron details across an area roughly the size of a U.S. dime without moving the sample. It produces gigapixel-scale images with high resolution, ideal for medical pathology and industrial inspection.
Researchers have developed a high-performance mid-infrared imaging system without lenses, capturing clear pictures over large distances and in low light. The system uses an optical pinhole inside a nonlinear crystal to form an image, which is then converted into visible light, allowing for distortion-free and large-depth imaging.
Researchers have developed a motion-compensation method that allows single-pixel imaging to capture sharp images of complex dynamic scenes. The new approach improves image quality and video smoothness in various scenarios, including surveillance and medical diagnostics.
A new study from North Carolina State University has confirmed the presence of hemoglobin in bone extracts from two dinosaurs, Brachylophosaurus canadensis and Tyrannosaurus rex. The researchers used Resonance Raman (RR) imaging to detect heme bound to globin proteins and heme bound to goethite, a mineral associated with iron oxidization.
Scientists have discovered that tiny brain vessels pulse to regulate blood flow through bursts of contraction and relaxation. The research reveals that these bursts originate from the walls of small arteries and spread through the vascular network in short intervals, providing insights into how the brain regulates its blood supply.
Researchers mapped the surface envelope glycoprotein of human endogenous retroviruses, opening doors to new diagnostic and therapeutic opportunities. The study revealed specific antibodies that target the viral proteins, potentially leading to new cancer immunotherapies and treatments for autoimmune diseases.
Researchers at Texas A&M University have developed a smart plastic that can self-heal and adapt to extreme conditions, making it ideal for aerospace and automotive applications. The material's unique properties allow it to restore its shape after deformation, improve vehicle safety, and reduce environmental waste.
A new platform enables real-time super-resolution imaging visual guidance during manipulation, allowing for precise control of feature-sized targets. The microlens-AFM probe improves imaging resolution by over 10-fold and enhances manipulation accuracy by 50%.
Researchers have developed a groundbreaking method to observe lysosomes in live suspended cells—quantitatively, in 3D, and without the use of chemical labels. The technology uses holographic tomography in flow cytometry configuration (HTFC) to identify morphological and spatial lysosomal changes in models of lysosomal storage diseases.
Researchers develop compact, noninvasive imaging system combining LC-OCT and Raman microspectroscopy to examine skin cancer structures and chemical composition. The AI model achieves high classification accuracy for basal cell carcinoma and other types, offering new insights into cancer development and behavior.
A new study explores catheter-based polarization-sensitive optical coherence tomography (PS-OCT) as a tool for improving the precision of electrode placement in deep brain stimulation. PS-OCT provides high-resolution intraoperative visualization of deep brain structures, distinguishing between white and gray matter more clearly than MRI.
A new study by Chinese researchers uses high-resolution satellite data to quantify global methane emissions from landfills, revealing open dumps emit 4.8 times more methane than engineered sanitary landfills.
The UK Biobank has completed a groundbreaking imaging project, scanning the brains, hearts, abdomens, blood vessels, bones and joints of 100,000 volunteers to understand how diseases develop. The project is already improving patient care in the NHS and beyond, with over 1,300 peer-reviewed scientific papers published based on the data.
The FiLM-Scope surgical microscope offers precise 3D imaging using 48 tiny cameras, creating a detailed 3D map of the scene in real time. This technology can expand possibilities in manual and robotic microsurgery.
A cardiac magnetic resonance imaging (MRI) scan usually takes anywhere from 30 to 90 minutes. The AI-assisted model developed by Mizzou researchers can turn low-quality MRI heart scans into high-quality images in less time, while improving patient experience and reducing costs.
A team of astronomers created a galactic masterpiece using the European Southern Observatory’s VLT, revealing previously unseen features in the Sculptor Galaxy. The map comprises thousands of colors, providing insights into the stars, gas, and dust within the galaxy.
A team of scientists from Colorado State University and the University of São Paulo have developed a seismological solution to improve the resolution of ultrasound images for lung monitoring. This breakthrough could lead to improved critical care for patients, including continuous lung monitoring at the bedside. The technique uses seis...
Researchers found that greenspace exposure is associated with widespread patterns of structural brain development during early adolescence, leading to better academic and mental outcomes. This study highlights the importance of integrating natural environments into urban and educational settings.
Researchers found persistent inflammation in heart and lungs of patients with long COVID, even after standard tests return normal results. This study uses advanced PET/MRI imaging to detect abnormal patterns that could serve as early warning signs of future cardiac and pulmonary conditions.
A team of researchers has revealed the molecular mechanisms underlying the binding of small extracellular vesicles to host cells, which could lead to the development of more effective cancer treatments. The study found that EVs primarily bind to laminin via CD151-associated integrin heterodimers and GM1, eliciting responses in recipien...
A novel cannula delivery system allows repeated, nondisruptive delivery of imaging agents to the mouse brain during long-term multiphoton microscopy. This innovation enhances longitudinal studies on brain function, disease progression, and potential treatments.
Four UTA faculty members - Cameron, Dias, Shiakolas, and Yuan - recognized by the National Academy of Inventors for their outstanding research discoveries. Their innovations have made a tangible impact on society through patents, licensing, and commercialization.
A retrospective study of 20 cases of pulmonary MALT lymphoma found characteristic HRCT features such as air bronchogram and bronchiectasis, predominantly in the left upper lobe. Pathologically, tumors exhibited monocytoid and centrocyte-like cells with minimal atypia and B-cell markers CD20 and CD3.
Researchers develop a new approach combining Phase Measuring Deflectometry and Shape from Polarization to accurately image specular surfaces without prior knowledge or assumptions. The single-shot method enables motion-robust measurements, pushing the limits for next-generation 3D sensors.
Full Waveform Inversion (FWI) technology provides unprecedented precision in seismic imaging, breaking resolution limitations of traditional methods. It characterizes complex structures within the Earth's interior and offers higher-resolution subsurface models.
The study reveals that the glycocalyx's main components are glycoproteins FMG1B and FMG1A, which regulate cilia adhesiveness without directly transmitting force for gliding motility. The findings expand knowledge of cellular regulation and protective mechanisms in other organisms.
A Colorado State University team has achieved a new milestone in 3D X-ray imaging technology by capturing high-resolution CT scans of the interior of a large, dense object using a compact, laser-driven X-ray source. This breakthrough offers a fast and non-destructive way to obtain detailed views inside dense structures.
Researchers discovered a new process by which cancer cells use small extracellular vesicles to spread to healthy tissue. The study found that these vesicles are primarily internalized by clathrin-independent endocytosis via galectin-3, which is facilitated by an increase in intracellular calcium concentration.
Researchers at Waseda University develop a new imaging technique that uses neutron activation to transform gold nanoparticles into radioisotopes, enabling long-term tracking of their movement in the body. This breakthrough could lead to more effective cancer treatments and precision monitoring of drug distribution.