A team of scientists from the Beckman Institute has received a $3 million grant to develop diagnostic tools and imaging agents for the early detection of Alzheimer's disease. They will use a combination of PET and MRI scans to target smaller beta-amyloid peptides and other signs of neuroinflammation and oxidative stress.
Researchers developed a new energy-efficient way to generate highly focused and finely controlled X-rays. The novel method uses electron waveshaping to produce X-rays with increased intensity and tunability.
A team of researchers led by URI Professor Brennan Phillips successfully demonstrated new technologies for capturing preserved tissue and high-resolution images of deep-sea animals in minutes, preserving them for advanced genomic study. This breakthrough enables faster species discovery and can inform extinction prevention efforts.
Researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a 10-centimeter-diameter glass metalens that can image the sun, moon, and distant nebulae with high resolution.
Researchers use water as a nonlinear medium to create a supercontinuum white laser covering an impressive spectral range from UV to far infrared. The resulting ultrabroadband source has potential in ultrafast spectroscopy, hyperspectral imaging, and scientific research.
Researchers provide new insights into STING's function in innate immunity, revealing its role as a scaffold that activates TBK1. They also found that cholesterol plays a crucial role in STING clustering and activation, offering a potential target for treating diseases associated with STING inflammation.
Ashok Veeraraghavan, a Rice University professor, has won the Edith and Peter O'Donnell Award in Engineering from the Texas Academy of Medicine, Engineering, Science and Technology. His research focuses on making invisible objects visible through imaging technology that tackles challenges beyond current technologies.
Researchers at TU Wien discovered that feldspar's unique surface geometry provides the perfect anchoring point for water molecules, enabling efficient cloud formation. The hydroxyl layer formed on the feldspar surface allows water molecules to stick and freeze, forming clouds.
Researchers have identified internationally significant rock art sites in Arnhem Land that were intentionally selected for their critical vantage points. The Flinders University research team used innovative methods to model the environmental conditions 15,000-28,000 years ago, shedding new light on the locations and roles of these sites.
Researchers developed a novel phase imaging technique using intensity correlation measurements that is immune to phase instability. This method can capture high-resolution images of transparent and optically thin samples, such as cell cultures, with improved accuracy.
Researchers developed a method to measure microvascular changes in the skin using AI and optoacoustic imaging technology, enabling non-invasive assessment of diabetes severity. The study identified 32 significant changes in blood vessels, which can be used to monitor disease progression.
Researchers developed an X-ray imaging technique that produces detailed images of living organisms at high resolution while minimizing radiation exposure. This advance enables small organisms to be studied over longer periods, revealing new insights into dynamic processes.
Researchers at ALMA achieved the highest resolution ever, observing a ring-like gas structure around R Leporis and confirming gas escape from the star. This capability will now be applied to young stars with protoplanetary disks where planets are forming.
Researchers found that green spaces alleviate extreme heat's negative impacts on human health, while densely packed buildings increase mortality risk. Urban design strategies incorporating different types of greenery are recommended to mitigate heatwave-associated mortality.
Scientists at Florida State University produced the first high-resolution images showing magnesium ions playing a crucial role in CRISPR-Cas9's DNA-cutting process. The discovery sheds light on how magnesium coordinates double-stranded breaks, providing new insights into the enzyme's functioning.
Researchers at the University of Würzburg developed a new method to precisely analyze infection pathways of dangerous virus variants using 'clickable' pseudoviruses. These harmless impostors retain their activity and are highly fluorescent, allowing for better visualization of viral infections in living organisms.
Researchers from Tsinghua University provide an overview of biofabrication methods for single-cell feature building blocks to reconstruct engineered living systems. The techniques aim to replicate natural tissues with precise control over microenvironment and structure, benefiting biomedicine applications.
A new deblurring algorithm has been developed to improve the resolution of microscopy images without amplifying noise. This breakthrough technique, called 'deblurring by pixel reassignment,' uses local gradients to sharpen images while preserving larger structures.
A team of researchers from POSTECH successfully engineered a dual metalens capable of switching between different imaging modes using a single lens. This innovation enables fast mode-switching and acquisition of high-resolution images for applications such as bio-imaging and cellular reactions.
Researchers have developed an integrated THz vortex beam emitter to detect rotating targets with remarkable precision. The system uses spiraling electromagnetic waves with orbital angular momentum to accurately measure the speed of a rotating object, with a maximum margin of error of just around 2 percent.
Advances in VR display technology have overcome the 'screen door effect' by introducing 2117 PPI LCDs with high partition mini LED backlighting. This enhances contrast, color accuracy, and viewing angles, making VR experiences more immersive.
Researchers created single-chain nanoparticles with thermoresponsive properties, which can be used to produce high-resolution internal images of the human body. These particles create a rich optical contrast that can be used to examine tumors more closely.
The study found that satellite cells possess an inherent capacity to sense and respond to regenerative cues independent of external signals from non-myogenic cells. Macrophages played a crucial role in regulating MuSC proliferation and differentiation, but their reduction led to impaired cell division and increased fibrosis.
Researchers at Johns Hopkins University have developed a new algorithm to filter out unwanted signals in medical images of darker skin tones, producing significantly sharper images. This breakthrough aims to mitigate bias in imaging technologies and improve surgical navigation and medical diagnostics for patients with diverse skin tones.
The UCLA-led team has developed a solution to improve cryo-electron microscopy's imaging capabilities for smaller protein molecules, enabling higher-resolution images. This advance is expected to help researchers identify specific locations on proteins that can be targeted for therapeutic purposes.
A new methodology for QPI of objects covered by random unknown phase diffusers uses diffractive optical networks and deep learning. The system axially spans ~70λ and performs all-optical phase recovery and quantitative imaging with high image quality and low power consumption.
GlowTrack, a non-invasive movement tracking method using fluorescent dye markers, improves the capture of diverse movements in laboratories. This technique enables easier comparison of movement data between studies, increasing scientific discovery and advancing fields like biology, robotics, and medicine.
Researchers developed an advanced terrain-smoothing technique to simulate complex weather phenomena, capturing detailed flow features and turbulence. The targeted smoothing method improves the accuracy of downslope windstorm predictions in urban areas, holding promise for more accurate weather forecasts.
A new imaging technique, multifocal acoustic radiation force-based reverberant optical coherence elastography (RevOCE), has been developed to measure the elasticity of multiple eye components simultaneously. This approach offers high resolution measurements of the stiffness of eye structures and could revolutionize how we study ocular ...
The Stevens INI is expanding its health disparities research with a new award to examine vascular causes of dementia in Asian Americans. The project aims to use innovative imaging techniques and clinical translations to better understand cerebral small vessel disease (CSVD) and its impact on cognitive impairment and dementia.
Researchers used X-ray tomoscopy to study freeze casting processes, observing the formation of complex, hierarchically structured materials with large surface areas. The technique provided high spatial and temporal resolution, revealing the dynamics of directional ice crystal growth and the formation of organic-looking structures.
Researchers at Shanghai Jiao Tong University have developed a new scattering matrix method that can sculpt light output with minimal optimization time. The method offers unparalleled nonlinear scattered light control, enabling high-resolution scanning microscopy and particle trapping through dense, scattering media.
The research team created a multi-spectral, super-low-dose photoacoustic microscopy system with improved sensitivity, enabling new applications and clinical translation. The system achieved up to capillary-level or sub-cellular resolution at greater depths than traditional optical microscopy methods.
Scientists have developed speckle diffraction tomography, which enables high-resolution images of thick biological samples with lateral resolution up to 500 nanometers. The technique offers full-field quantitative imaging capabilities, revealing nanoscale features in complex specimens.
Researchers developed a new algorithm to recover the 3D refractive index distribution of biological samples exhibiting multiple types of light scattering. The algorithm optimizes intensity diffraction tomography (IDT) for thick biological samples, achieving high-speed acquisition and high resolution.
Lead-free Cs3MnBr5 anti-perovskite nanocrystals embedded in glass matrices enable tunable emission and ultra-stable X-ray imaging. The results achieve exceptional X-ray detection limits, spatial resolutions, and dose irradiation stability.
Using MRI instead of CT with CTA alone in patients presenting to the ED with dizziness was associated with greater critical neuroimaging results and more frequent echocardiography. Patients with dizziness undergoing MRI showed a lower frequency of 90-day ED readmissions compared to those discharged after CT with CTA alone.
Researchers at HZDR are developing a low-cost muon detector for non-destructive condition monitoring of industrial facilities. The detector aims to reduce costs and enable long-term monitoring, with potential applications in bridge inspection and nuclear waste management.
Engineers at Rice University and the University of Maryland developed NeuWS, a technology that can undo light scattering effects, enabling full-motion video through various media. The technology measures wavefronts to rapidly decipher phase information, overcoming the 'holy grail problem' in optical imaging.
Researchers have found evidence of 20 million years of 'hot spot' magmatism under the Cocos plate, with a long-lived melt channel that originated from a mantle plume. The study suggests that this channel is regionally extensive and may be a widespread source for intraplate magmatism.
Researchers at the Beckman Institute for Advanced Science and Technology have developed a new framework for super-resolution ultrasound using deep learning, reducing processing speeds from minutes to seconds. The new technology enables real-time blood flow visualization, overcoming challenges faced by conventional methods.
A new camera technology developed by Aarhus University and Newtec Engineering A/S aims to make it easier to recycle plastic materials. The technology uses hyperspectral imaging to analyze the chemical composition of plastic waste, allowing for the removal of unwanted additives that may be banned or harmful.
Researchers at the University of Exeter have captured the structure of a commonly used phage, filamentous phages, which will enable the development of new biotechnology applications. The new insights gained from this research will help improve phage display and other uses in drug discovery.
Scientists have developed a new method to deliver genetic information to stem cells using nanoparticles coated with a specific polymer, enabling more efficient control over cellular differentiation. This innovation has the potential to improve the efficiency and effectiveness of regenerative medicine treatments.
Scientists have created a new way to image and track macrophages in the body using ultrasound-enhanced immune cells. This method has potential for early cancer detection and monitoring of therapeutic efficacy. The technique involves attaching microbubbles to macrophages, allowing for high-resolution tracking images.
A new high-speed two-photon microscope was developed with an unprecedented line scanning frequency of 400 kHz, achieving up to 10,000 frames per second. This allowed for precise observations of complex biological processes in living tissues, including calcium signal propagation and blood flow measurements.
A mobile application utilizing Python and a single-element ultrasound transducer has been developed for photoacoustic tomography (PAT) image reconstruction. The application successfully reconstructs high-quality images with signal-to-noise ratio values above 30 decibels, making it suitable for point-of-care diagnosis in low-resource se...
Researchers have developed a non-invasive technique using laser speckle imaging to visualize microvasculature in donor hearts and detect abnormal blood flow. The method enables precise visualization of blood circulation, potentially identifying hearts suitable for transplantation.
Researchers discovered a 'cocktail' of human antibodies that show promise in fighting severe SARS-CoV-2 infections, including Omicron variants. The study revealed how the original Moderna vaccine could prompt the body to produce these broad-spectrum antibodies.
The American Roentgen Ray Society presents its 2023 Honorary Lecture on Advanced High-Resolution CT, dedicated to the late Dr. W. Richard Webb, who transformed thoracic imaging with his foundational work in HRCT. The lecture explores multiple conditions diagnosed via HRCT and the radiologist's role on multidisciplinary teams.
Researchers develop innovative method to analyze ancient bones, making collagen quantifiable and mapping possible. This technique supports the selection of samples for radiocarbon analysis, preserving valuable material and reducing destruction.
Researchers have developed a new type of microscope objective inspired by the eyes of scallops, which can capture images in various immersion media, including liquids. This innovative approach uses a mirror instead of lenses and has been shown to provide excellent image quality in homogeneous fluids as well as in air.
Researchers have found that embryos in pregnancies ending in miscarriage take four days longer to develop in the womb than those in live births. This delay is associated with a higher likelihood of miscarriage and may be used to estimate pregnancy outcomes.
A team from Chalmers University of Technology has developed a method to observe the formation of lithium microstructures in real-time using X-ray tomographic microscopy. This breakthrough aims to improve the safety and capacity of lithium metal batteries, which could replace traditional lithium-ion batteries in the future.
A new snake family, Micrelapidae, was identified through an international study led by Tel Aviv University researcher Prof. Shai Meiri. The family includes only three species, two in Africa and one in Israel, and diverged from the rest of the evolutionary tree about 50 million years ago.
Researchers used AI to analyze thousands of satellite measurements, revealing four categories of ice movements linked to meltwater flow. The study provides insight into how the Greenland ice sheet reacts to warmer temperatures and more meltwater.
Researchers from City University of Hong Kong have developed a novel, tiny device to observe liquid-phase electrochemical reactions in energy devices at nanoscale. The device enables real-time and high-resolution visualization of complex electrochemical processes.
University of Illinois scientists developed a way to accurately map tilled land in real-time using ground, airborne, and satellite imagery. The method increased mapping accuracy by 67% compared to upscaling directly from the ground to the satellite.
Researchers at Rice University have developed a new fluorescent dye that can cross the blood-brain barrier, allowing for noninvasive brain imaging and differentiation between healthy tissue and tumor cells. The dye's long-lasting fluorescence enables stable imaging over extended periods.
Researchers have developed shortwave-infrared and thermal imaging techniques to accurately diagnose active dental caries. SWIR-based approach shows superior results in detecting lesions, while thermal imaging proves less effective.