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New sensor grids record human brain signals in record-breaking resolution

The new sensor grids offer 100 times higher resolution than existing technology, allowing for more precise identification of seizure origins and preservation of healthy brain tissue. Longer term, the technology holds potential for permanent implantation to improve life quality for people with paralysis or neurodegenerative diseases.

SourceUniversity of California - San Diego·JournalScience Translational Medicine·TypeExperimental study·DateJan 19, 2022

Combating antibiotic resistance

The need for new antibiotics is critical due to rising antibiotic resistance, which kills over 35,000 people annually in the US. Research by Harvard Medical School aims to develop better antibiotics by targeting essential bacterial proteins.

SourceHarvard Medical School·JournalScience·DateNov 3, 2021

Light in, sound out: photoacoustic probe helps find and fight Wilson's disease and other maladies

Researchers developed a non-toxic, small-molecule probe that provides real-time visualization of disease progression, overcoming limitations of MRI and PET imaging. The probe binds copper ions and detects dysregulated levels, accurately identifying Wilson's disease and other maladies.

SourceBeckman Institute for Advanced Science and Technology·JournalProceedings of the National Academy of Sciences·TypeRandomized controlled/clinical trial·DateSep 30, 2021

Seeing (infra)red: Researchers develop software to enhance infrared imaging-based cancer diagnosis

A team of Beckman researchers developed software to boost infrared imaging-based cancer diagnosis, enhancing image resolution and accelerating recording speeds. The software integrates data analysis and reduces limitations associated with IR imaging, making it faster and more accurate.

SourceBeckman Institute for Advanced Science and Technology·JournalChemometrics and Intelligent Laboratory Systems·TypeComputational simulation/modeling·DateAug 5, 2021

Mapping coral from the air

Researchers developed an airborne approach to map live coral distribution in the Hawaiian Islands, revealing a negative correlation between nearshore development and live coral cover. The study suggests that this cost-effective method could provide high-resolution monitoring of coral health at a low cost.

SourceProceedings of the National Academy of Sciences·JournalProceedings of the National Academy of Sciences·DateDec 14, 2020

Reconstruction of eye tissue gives new insight into outer retina

Scientists at the University of Southampton have made a breakthrough in reconstructing eye tissues from the outer retina using serial block face scanning electron microscopy. The study provides a clear picture of the 3D organisation of the retinal pigment epithelium, which could help understand causes of damage leading to sight loss.

SourceUniversity of Southampton·JournalInternational Journal of Molecular Sciences·DateDec 2, 2020

Tailored light inspired by nature

A team of international researchers developed propagation-invariant light fields using caustics that do not change during propagation. This breakthrough enables new applications in high-resolution microscopy, material processing, and multidimensional signal transmission.

SourceUniversity of Münster·JournalNature Communications·DateJul 29, 2020

Deep learning enables real-time imaging around corners

Researchers developed a new laser-based system that can image around corners in real time, enabling applications such as detecting hazards or pedestrians in self-driving cars. The system uses deep learning to reconstruct hidden objects at high resolutions and speeds.

SourceOptica·JournalOptica·DateJan 16, 2020

Finding chemicals inside a cell

Researchers at Xiamen University have created a device that enables the direct detection and mapping of chemicals inside biological cells. This breakthrough technique, called near-field desorption postionization time-of-flight mass spectrometer (NDPI-TOFMS), overcomes challenges in high-resolution imaging and provides undistorted chemi...

SourceWiley·JournalAngewandte Chemie International Edition·DateFeb 7, 2019

New compact hyperspectral system captures 5-D images

A new compact hyperspectral system captures 5-D images with high speed and accuracy, benefiting applications such as optical-based sorting and personal medical monitoring. The system uses structured light to create detailed digital archives of historically valuable artifacts.

SourceOptica·JournalOptics Express·DateAug 28, 2018

Nano-optic endoscope sees deep into tissue at high resolution

Researchers have developed a new class of endoscopic imaging catheters that overcome the limitations of current systems, achieving higher resolution and functionality. The nano-optic endoscope incorporates metalenses into its design, enabling high-resolution imaging at extended depth of focus without complex optical components.

Using high-resolution satellites to measure African farm yields

Researchers developed a method to estimate crop yields from space using high-resolution satellites, which could improve agricultural productivity and test intervention strategies. By combining satellite imagery with computer models of crop growth, they achieved surprisingly accurate predictions of actual productivity on the field.

SourceStanford's School of Earth, Energy & Environmental Sciences·JournalProceedings of the National Academy of Sciences·DateFeb 13, 2017

Image-based modeling

Researchers developed a novel image-based simulation approach that accounts for realistic architectural non-idealities and flow physics in tissue engineering scaffolds. This technology allows for correlating cell behavior and tissue growth with flow, tracking relationships over time via repeated scanning.

SourceWorld Scientific·JournalTECHNOLOGY·DateDec 29, 2016