Articles tagged with Molecular Imaging
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found that responders with high exposure to the dust cloud had high-risk features of atherosclerosis and impaired vascular reactivity. The study used MRI imaging to evaluate cardiovascular risk in WTC first responders.
Researchers at Purdue University have developed a new imaging technology that uses nanosecond laser pulses to measure ultrasound signals from molecules, enabling precise three-dimensional images of arterial plaques. This breakthrough could lead to better diagnoses and treatments for cardiovascular disease and other disorders.
A molecular imaging procedure using PET/CT and F18 NaF radiotracer accurately diagnoses and manages chronic back pain by pinpointing the source of abnormal bone reaction. In a study, this method was found to be highly effective in more than 85% of cases, providing relief for patients with hardware implants or bone grafts.
Researchers use molecular imaging to gauge heart efficiency in subjects with a pathogenic mutation linked to HCM. They find carriers of the mutation already have less efficient hearts despite the absence of any symptoms. Alcohol septal ablation is shown to be an effective treatment for symptomatic patients who remain symptomatic despit...
A study published at SNM's 58th Annual Meeting found that molecular imaging, specifically FDG-PET scans, can effectively diagnose the cause of fever of unknown origin. The research suggests that FDG-PET may improve patients' prognosis and cut healthcare costs by providing a non-invasive diagnostic tool.
Researchers combined two molecular imaging agents to create a powerful new tool for acquiring information about the extent of a patient's cancer. The results showed that combined 18F NaF and 18F FDG PET/CT imaging provided good-quality imaging of both skeletal and extra-skeletal malignant lesions from various cancers.
Researchers have successfully used oatmeal products radiolabeled with a medical isotope to image stomach emptying in molecular imaging studies. The study demonstrated that prior boiling and labeling of oatmeal improves radiolabeling efficiency, making it an effective alternative to egg meal for patients with dietary restrictions.
Researchers developed a molecular imaging technique that can detect reduced blood flow in diabetic hearts, potentially saving lives. The study found that this method is safe and beneficial for predicting cardiac events in diabetic patients suspected of having ischemic heart disease.
Researchers found significant improvements in lesion detection with whole-body TOF FDG PET scans, particularly in larger patients and shorter studies. TOF scans yielded better image signal-to-noise due to travel time consideration, reducing scanning time and patient motion.
A new study uses PET scans to image metabolic changes in thyroid cancer patients treated with vandetanib, a protein kinase inhibitor. The findings show that PET imaging can help define the therapy response and identify potential markers of treatment efficacy.
A new molecular imaging technology has been developed by researchers at Universidad Carlos III de Madrid to detect live cellular processes. This technology differs from conventional medical imaging, allowing for earlier detection of anomalies and facilitating treatment.
A study found that PET/CT scans can predict local recurrence in lung cancer patients treated with radiofrequency ablation by analyzing lesion size, tumor type, and glucose metabolic activity. This non-invasive tool may help improve diagnosis and treatment of lung cancer.
The Euro-BioImaging project will develop a comprehensive plan to construct and operate a set of complementary imaging infrastructure facilities across Europe. This will enable scientists to access state-of-the-art imaging technologies, receive training, and facilitate the translation of basic results to medical applications.
Researchers have developed a new imaging technology that combines photoacoustic tomography with gold nanobeacons, allowing for unprecedented detail in visualizing blood vessel formation. This breakthrough has the potential to help healthcare providers diagnose diseases earlier and more accurately.
A new study using positron emission tomography (PET) and magnetic resonance imaging (MRI) found that traumatic brain injuries lead to widespread decreases in brain functioning, particularly in the hippocampus. The research suggests a time window during which intervention could mitigate long-term neurological consequences.
A molecular imaging technique may help identify early response to treatment in cisplatin-resistant ovarian cancer, potentially reducing unnecessary side effects and offering more effective treatments. Researchers used a PET probe to monitor tumor growth in mice with human ovarian cancer.
Studies show molecular imaging improves evaluation and treatment planning for various cancers, including thyroid cancer, lymphoma, and non-small cell lung cancer. The technique allows doctors to identify disease severity and extent, providing personalized care and adjusting treatment plans accordingly.
A new imaging method can identify high-risk patients with potentially life-threatening cardiovascular conditions, helping physicians determine which patients are best suited for implantable cardioverter defibrillator therapy. This technique also helps avoid overuse or underuse of ICD treatment.
Researchers developed a novel optical imaging technique called Cerenkov Luminescence Imaging (CLI) that could lead to faster development of radiopharmaceuticals. CLI harnesses the speed of light to visualize medical isotopes, overcoming current limitations in nuclear imaging modalities.
The meeting showcased groundbreaking research and development worldwide in molecular imaging and nuclear medicine, with a focus on using molecular imaging to understand disease mechanisms and improve patient health. Key findings included advances in Alzheimer's disease identification and recurrent prostate cancer detection.
Chester A. Mathis receives SNM's 2010 Aebersold Award for his groundbreaking work on early detection in Alzheimer's disease using positron emission tomography (PET) imaging techniques. This recognition acknowledges the significant contributions of Dr. Mathis to advancing molecular imaging and nuclear medicine.
Bengt Roland Långström, a professor at Uppsala University in Sweden, has been recognized for his work in nuclear medicine. He is being honored with the Georg Charles de Hevesy Nuclear Pioneer Award for his over 20 years of experience in synthesizing and applying radiolabeled tracers for PET.
Researchers developed a non-invasive imaging technique combining PET and CT scans without bowel preparation, detecting all significant polyps found by colonoscopy. Patients preferred this method over colonoscopy due to its comfort and lack of sedation.
The Journal of Nuclear Medicine published a supplement on cardiovascular molecular imaging, discussing its potential to diagnose heart diseases earlier. The publication combines various imaging techniques, such as ultrasound, MRI, and radiotracers, to improve management of cardiovascular disease.
Research published in The Journal of Nuclear Medicine suggests that molecular imaging using 18F-FDG PET/CT can help diagnose acute and chronic aortic dissection. This non-invasive technique can provide images to determine the difference between acute and chronic dissections, helping doctors decide the best course of treatment.
The Society of Nuclear Medicine and Molecular Imaging (SNM) has received a $48,000 grant from the Agency for Healthcare Research and Quality (AHRQ) to develop research on comparative effectiveness of PET and other molecular imaging techniques. The primary emphasis will be on cancer diagnosis and management, with cardiology and neurolog...
A new imaging technique using FDG PET can help doctors plan cardiac procedures, reducing cost and improving patient outcomes. The study found a trend toward better patient outcomes when FDG PET is used in diagnostic work-up.
SNM's Clinical Trials Network has gained a new member, Eli Lilly and Company, which will support the initiative to facilitate the development of therapeutic medicines. The network aims to streamline drug discovery and integrate imaging biomarkers into clinical trials, ultimately leading to personalized diagnostics and therapies.
Researchers develop fluoromodules, dye-protein complexes that provide alternatives to GFP with a wider selection of colors and increased photostability. This technology enables real-time monitoring of biological activities in living cells.
Springer has partnered with the Korean Society of Nuclear Medicine (KSNM) to publish the journal Nuclear Medicine and Molecular Imaging. The journal will be available in both print and electronic formats, providing a platform for high-quality research and discussion on nuclear medicine and related sciences.
A new imaging technique combines ultrasound and specially modified contrast agents to detect cancer at the molecular level, allowing for early detection and potentially saving lives. The technique uses microbubbles paired with a peptide that binds to tumor vessel cells, enabling visualization of tumor activity.
A new study provides clear pediatric PET dose guidelines, allowing clinicians to calculate the optimal radiotracer dose based on a child's weight. The findings suggest that patients can receive high-quality images with reduced scan time or lower doses, minimizing radiation exposure for young children.
The Society of Nuclear Medicine and Molecular Imaging's Clinical Trials Network Workshop explored the integration of imaging biomarkers into clinical trials, emphasizing quality and standardization. Experts shared insights on overcoming challenges and harmonizing data across multiple sites.
The summit explored ways to use nanotechnology in medical imaging and therapy, focusing on targeting diseases such as cancer, neurological conditions, and cardiovascular disease. Experts discussed regulatory frameworks, design considerations, and future directions for this rapidly evolving field.
Researchers at Lawrence Berkeley National Laboratory have developed a copper-free version of click chemistry to label glycans in live mice, providing new insights into glycobiology and molecular imaging. The technique overcomes the toxicity issue of conventional copper-catalyzed reactions.
A large-scale study demonstrates that transplanted cells produced dopamine, leading to improved motor symptoms and brain function. Long-term clinical outcomes revealed sustained improvements over a four-year period.
Researchers found that a combination of single photon emission computed tomography (SPECT) and low-dose CT provided accurate diagnoses with high sensitivity and specificity. The study suggests that this technique may improve patient outcomes by reducing the mortality rate associated with untreated pulmonary embolism.
Researchers used PET scans to identify neuroinflammation in the brains of schizophrenics and migraine sufferers, shedding light on the underlying causes of these conditions. The findings have the potential to transform diagnosis and treatment options, particularly for schizophrenia.
A new molecular imaging technique using PET imaging shows promising results in evaluating and predicting the course of endometrial carcinoma. The technique combines estrogen receptor expression imaging with 18F-FDG PET to improve diagnostic accuracy, potentially saving women from unnecessary operations and biopsies.
A new study published in The Journal of Nuclear Medicine shows that PET/CT scans with the imaging agent choline can detect recurring prostate cancer sooner than conventional imaging technologies. Researchers found a strong association between PET/CT detection and PSA levels, and suggest using specific criteria to reduce unnecessary scans.
A new study presents PET scan results that can accurately diagnose specific types of dementia, such as Alzheimer's disease, in the early stages. This can lead to targeted treatments and improved care outcomes for over 5 million newly diagnosed patients each year.
Researchers have developed a novel form of treatment using an alpha-particle emitting radiopeptide that targets and destroys cancer cells while sparing healthy tissue. The study found that this therapy was significantly more effective at tripling the survival rate of mice with recurrent prostate cancer compared to traditional treatments.
Researchers at SNM's 56th Annual Meeting propose a novel approach to reconstructing data that could enable the development of a hybrid PET-MR system. The new method uses MR images as a geometrical reference to estimate attenuation and improve accuracy.
Researchers at SNM's Annual Meeting discovered that combining motion-frozen technology and high-definition PET enhances cardiac imaging, revealing defects invisible to physicians. The method provides exceptional image quality and significantly changes the diagnosis of patients with heart disease.
Researchers found that combining high-resolution and high-sensitivity collimation in SPECT scans improves image quality for small tumors. This study suggests a new approach to overcome tradeoffs in SPECT image quality, especially for imaging small tumors.
Michael R. Kilbourn, a professor at the University of Michigan, received the prestigious Paul C. Aebersold Award for his contributions to molecular imaging and nuclear medicine. He has advanced research efforts in various areas, including positron emission tomography (PET) radiopharmaceuticals.
Alan Davison, Alun G. Jones, and Michael J. Abrams discovered a new class of technetium complexes that showed localization in cardiac tissue after intravenous administration, leading to the development of myocardial perfusion imaging agents. Their work has enabled millions of people to receive better diagnosis and treatment for heart c...
The Society of Nuclear Medicine and Molecular Imaging has published a comprehensive guide to PET scanning in cancer therapy, providing international guidelines and criteria for response assessment. The new supplement aims to improve tumor response assessment and treatment monitoring with FDG PET imaging.
Researchers at UC San Diego are developing new diagnostic tools to detect early-stage cancers using advanced imaging technologies. They aim to characterize tumor aggressiveness and monitor chemotherapy effectiveness, enabling more effective treatment decisions.
Researchers have developed a new technique called liquid STEM that enables the imaging of individual molecules in biological cells, with improved resolution and speed compared to existing methods. This innovation has potential applications in energy science and the development of molecular probes.
Researchers at Memorial Sloan Kettering Cancer Center developed a new generation of microscopic particles, called C dots, that are biologically safe and stable. These particles can be customized to target specific molecules on tumor surfaces, enabling earlier detection and more personalized treatment options.
Researchers used SPECT to detect brain perfusion abnormalities in fibromyalgia patients, revealing correlations with pain intensity and emotional responses. The study confirms fibromyalgia as a real disorder, not just depression-related, and may improve treatment prediction.
A single dose of EPO immediately after a heart attack reduces apoptosis and limits damage to the heart. The study found a 2.7-fold reduction in tracer accumulation, indicating less damage to heart tissue.
The Journal of Nuclear Medicine is now free and open to the public six months after publication, accelerating access to new research and advancing understanding of nuclear medicine and molecular imaging. This move reflects the journal's exceptional quality and influence as an academic and professional resource.
Recent advancements in cardiac imaging have led to the detection of impairments in cellular processes that precede changes in morphology and function. These early stages can be identified through various imaging techniques such as PET, nuclear imaging, MRI, ultrasound, and optical imaging.
Thakur's work has advanced excellence in healthcare through the development of radiopharmaceuticals and imaging techniques, including a new monoclonal antibody for detecting infection. The 2008 Benedict Cassen Prize recognizes his major advance in basic or clinical nuclear medicine science.
Peter J. Ell, director of the institute of nuclear medicine and chair of nuclear medicine at UCL, is awarded the Georg Charles de Hevesy Nuclear Pioneer Award for laying the foundations of nuclear medicine in Europe. The award recognizes his pioneering efforts in developing molecular imaging techniques, including SPECT.
The Society of Nuclear Medicine and Molecular Imaging (SNM) has awarded $170,000 in research grants to support nuclear medicine and molecular imaging research. This funding supports independent research projects, including the work of talented young scientists who will further advance diagnostic tools and treatments.
The Society of Nuclear Medicine and Molecular Imaging (SNM) has awarded significant grants to support molecular imaging research, providing opportunities for young scientists to pursue cutting-edge research in emerging fields. The awards aim to advance patient care by investing in promising researchers working on vital medical practices.
A team of researchers led by University of Notre Dame physicist Bolizsár Jankó presents an overview of research into quantum jumps and fluorescence intermittency. The phenomenon, known as 'blinking,' reveals unexpected deviations from Bohr's predictions in various systems.