Articles tagged with Neuroimaging
Research suggests that persistent pain drives progressive changes in the hippocampus, a brain region involved in emotional regulation. This can shape whether people develop depression or remain emotionally resilient. The study's findings challenge the idea that depression is an inevitable consequence of long-term pain.
Dr. Phillips's laboratory identifies abnormalities in prefrontal-striatal-limbic circuitry as biomarkers for bipolar disorder before symptoms appear. Her team tracks neural network development from infancy through young adulthood.
Researchers have developed an 'ECI patch' that reads brain signals and controls cars with 93.5% accuracy. The patch, powered by ultra-thin sheets called MXene, detects fatigue and mental states without causing skin irritation.
Researchers at Kyushu University develop a new tissue-clearing reagent, SeeDB-Live, enabling repeated, reversible, and real-time imaging of living brains at greater depth and clarity. This breakthrough allows scientists to visualize neural activity in living mice and brain slices, offering new insights into brain dynamics and function.
A team of researchers has developed a method to decode fluctuations in spontaneous pain intensity in individuals with chronic pain using extensively sampled functional MRI data. The study found that neural patterns underlying pain differ markedly between individuals, highlighting the importance of individualized brain-based biomarkers.
The Society for Brain Health is a new collaborative body dedicated to enhancing cognitive capacity, longevity, and proactive health optimization through cutting-edge research and tools. Its founding members include prominent neuroscientists and experts in the field of brain health.
Researchers found that brain synchrony between mothers and children is equally strong when playing in the native language or an acquired second language. This suggests that multilingualism can support healthy communication and learning without disrupting the brain-to-brain connection.
Prolonged grief disorder (PGD) is characterized by intense emotional pain and longing for the deceased. Research highlights disruptions in reward-related brain networks as key to explaining why grief persists in some individuals.
Researchers have explored how human mesenchymal stem cells can help repair brain injury in children born preterm. The PREMSTEM project has investigated the use of h-MSCs to address brain injury caused by early-life birth, with promising results showing a positive impact on brain damage and inflammation.
A new study by Leopoldo Petreanu's team shows that different visual experiences result in distinct patterns of organization in feedback connections. Mice with miniature goggles biased to see edges oriented at specific angles had unique tuning properties and patterns in these connections.
The FENS Forum 2026 will be Europe's largest neuroscience congress, covering areas of basic to translational research. Journalists can register for free and attend symposia and poster sessions.
Researchers at the University of Notre Dame investigated how brain networks are organized and work together to form a unified system. They found evidence for system-wide coordination in the brain that is both robust and adaptable, suggesting that intelligence reflects how brain networks are coordinated and dynamically reconfigured.
Researchers at Karolinska Institutet created the first activity-based maps of the prefrontal cortex, revealing a hierarchy of information flow rather than tissue structure. This challenges traditional definitions of brain regions and has major implications for understanding brain organisation overall.
A 12-month aerobic exercise program reduced brain age by 0.6 years, while a control group showed a slight increase. The study suggests that following current exercise guidelines may help keep the brain biologically younger in midlife, supporting clearer thinking and stronger memory.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
Research finds that musical improvisation involves a dynamic reconfiguration of the brain between emotion, technique, and structure. The study proposes a scalable method for exploring the neural basis of spontaneous creative behavior, highlighting the importance of interaction between networks over time.
A mouse study by Okinawa Institute of Science and Technology researchers has found that acetylcholine release is essential for breaking habits and enabling new choices to be made. The study's findings may help understand diseases such as Parkinson's disease, addiction, and obsessive-compulsive disorder.
A study among WTC responders with chronic PTSD found measurable physical changes in their brain structure, including cortical changes and imbalance of myelinated to unmyelinated neurons. These changes were most strongly associated with re-experiencing symptoms in individuals with PTSD.
Researchers at Brown University have created a bioluminescence tool that enables the measurement of activity in living brain cells without damaging them. The CaBLAM tool uses bioluminescent light production to capture single-cell and subcellular activity at high speeds, allowing for longer recordings and reducing hardware requirements.
A study published in Biological Psychiatry identifies a distinct immuno-inflammatory biomarker in the brain linked to immune system dysfunction and poorer response to standard treatments. The findings provide potential value for clinical prediction and precision therapies.
The study used advanced neuroimaging methods to identify early, network-level changes in over 3,000 individuals at varying levels of risk for psychosis. Individuals at high clinical risk exhibited early disruptions in brain network organisation despite mild clinical symptoms.
Researchers developed an experimental protocol to monitor brain activity in mouse models, finding that brain activity shifts from inner layers to cortex throughout the day. This discovery could lead to new methods for assessing fatigue and understanding mental health issues.
The MiniVolt microscope enables recording of both rapid electrical spikes and smaller sub-threshold voltage changes in freely moving animals. This allows for a more complete view of how brain cells process information during natural behavior, leading to potential new treatments for neurological disorders.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.
Researchers have developed a new method to image brain tissue using X-rays, achieving unprecedented resolution and resolving the long-standing challenge of studying connectomics. The technique uses a specially designed epoxy resin and cooled stage to stabilize the sample, enabling the study of synapses and neural connections in three d...
Researchers at the University of Plymouth have successfully used transcranial ultrasound stimulation (TUS) to change the function of a deep region of the human brain, specifically the nucleus accumbens. This tiny element is triggered by enjoyable experiences and helps us learn behaviours that lead to rewards.
Researchers analyzed clips from Hollywood films to identify brain structures linking visual and tactile experiences. They discovered eight remarkably similar maps in the visual cortex, mirroring the body's organization in the somatosensory cortex.
Researchers identified five phases of brain structure, each supported by four turning points between birth and death, revealing key developments in cognitive performance, neural efficiency, and regional compartmentalization. The study provides context for understanding why brains develop differently at various stages of life.
A USC study mapped tiny structural differences in white matter among children and young adults with autism, pinpointing patterns that earlier methods would have missed. The findings highlight the importance of developing new methods to better understand brain differences in autism.
A new study found that individuals with a history of major depression showed higher MRI markers associated with neuroinflammation in the VTA, suggesting increased extracellular inflammatory processes. Current depressive symptom severity was associated with distinct microstructural changes indicating different underlying pathophysiologi...
Researchers will study neural mechanisms of visual perceptual learning (VPL) to generalize across the visual field, improving vision rehabilitation and AI systems. The project aims to develop a unified model of visual processing, VPL, and attention.
Researchers developed a novel method called cytoarchitecture-based link estimation (CABLE) to infer axonal pathways from routine histology, reconstructing three-dimensional whole-brain fiber tracts at cellular scale. CABLE outperforms existing neuroimaging tools in resolving complex geometries and has potential applications in psychiat...
A new study by Carnegie Mellon University's Wood Neuro Research Group uses advanced brain imaging and a digital visualization tool to better understand how pain is processed in the brain for people with sickle cell disease. The team found that patients had reduced connectivity across key brain networks linked to pain perception, partic...
A study published in Radiology found that soccer fans' brain activity is triggered by positive and negative emotions when watching their favorite team play. The researchers used fMRI to examine the brain's response to goal sequences from matches, revealing patterns of neural activation associated with social identity and fanaticism.
A new brain atlas developed by UCL researchers enables analysis of brain scans at an unprecedented level of detail, opening up possibilities for studying neurodegenerative diseases and ageing. The atlas uses AI to identify hundreds of brain regions in living patients quickly and consistently.
Researchers have developed a new large-scale brain data resource that integrates data from five studies of brain development in children and young adults across three continents. The Reproducible Brain Charts (RBC) project provides a harmonized dataset for tracking changes in brain structure and function, allowing researchers to better...
A mega-analysis of 16 neuroimaging studies found that brain activity in reward and social processing regions can predict which messages are well-received by both scanned individuals and broader audiences. Effective messages activate brain responses related to mentalizing, anticipating rewards, and evoking emotions.
Researchers discovered that brains and economies follow similar rules in crisis, using physics principles to predict collapse and recovery. The study found that networks closer to first-order transition show faster collapse and slower recovery after a crisis.
Researchers have discovered a key role for the Frazzled protein in fruit fly neural circuits, revealing how it helps neurons form reliable connections. The study showed that when Frazzled is missing or mutated, neurons fail to form proper electrical connections, leading to communication breakdowns.
A University of Minnesota Medical School research team, led by Ziad Nahas, has been awarded a $4.4 million grant to explore how large-scale brain networks regulate mood in bipolar disorder. The team will test a novel type of brain stimulation called Personalized and Adaptive Cortico Electrostimulation (PACE) to relieve symptoms and ide...
Recent advances in deep learning techniques have overcome limitations in spatial and temporal resolution of BOLD-fMRI. DL models improve image quality through super-resolution reconstruction, automate segmentation, and enhance registration, enabling finer localization of neural activity and more precise brain activity quantification.
Researchers used data from the Human Connectome Project to build computational models that linked connectivity with brain activation across various cognitive processes. The findings show a consistent correlation between connectivity and function, suggesting that specific patterns of connectivity can predict brain activity.
Researchers have discovered that deep sleep plays a crucial role in controlling cerebrospinal fluid dynamics, which is essential for clearing waste from the brain. During slow-wave sleep, changes in cerebrospinal fluid signals are time-locked to slow brain waves and other neural events.
A new study from Washington University School of Medicine found that social conflicts, particularly family fighting and peer bullying, were the strongest predictors of near- and long-term mental health issues in teens. The research also revealed sex differences in how boys and girls experience stress from peer conflict.
A new study reveals that astrocytes, a type of glial cell, are responsible for stabilizing memories through repeated engagement. The researchers found that Fos activity in astrocytes only occurs during recall, and that these cells can be activated to produce stable memories.
MetaSeg achieves the same segmentation performance as U-Nets but requires 90% fewer parameters, making medical image segmentation more cost-effective. The new approach leverages implicit neural representations to quickly adjust to new images and decode accurate labels.
A researcher is exploring the hidden functions of vascular-neuronal interfaces to uncover how blood vessels influence brain development and connectivity. The study aims to develop new therapeutic strategies for diseases caused by disrupted communication between blood vessels and neurons.
Researchers have developed an AI model that creates a detailed map of the mouse brain featuring 1,300 regions/subregions. The CellTransformer model uses spatial transcriptomics data to identify previously uncharted subregions of the brain, opening new avenues for neuroscience exploration.
A study by UC Riverside researchers identifies a strong connection between demyelination and seizure activity in multiple sclerosis. The findings suggest targeted treatments could address the root cause of seizures without suppressing overall brain activity.
Scientists have developed a device that allows them to stimulate three or five precisely defined points in the brain simultaneously, improving the technique of ultrasonic stimulation. This non-invasive method has the potential to treat various brain diseases, including Alzheimer's, epilepsy, and depression.
Adolescents who frequently prefer solitude show measurable differences in brain structure and function, with weaker connections and greater fragility in social circuits. Clinicians can help families recognize risks by spotting early patterns of persistent withdrawal, opening the door to strategies that may protect mental health.
Researchers developed a fiber-optic method to track Alzheimer's plaques in freely behaving mice, allowing for real-time monitoring and long-term tracking of pathological changes. The technique uses fluorescent dye to bind specifically to amyloid fibrils and provides a minimally invasive way to study disease progression.
Professor John O'Brien's research focuses on understanding the impact of electrical synapses and gap junction plasticity on the retina and other neurological functions. The study aims to identify proteins that control electrical synapse strength, shedding light on their role in human disorders such as autism and seizures.
A new study found that healthy habits such as optimism, good sleep, and social support are strongly linked to healthier brains. Study participants who reported the most protective factors had brains eight years younger than their chronological age, and their brains aged more slowly over time.
A $10-million grant from the Weston Family Foundation will fund a project at McGill University to discover new Alzheimer's biomarkers. The ultra-high-sensitivity whole body PET/CT scanner, Panorama GS, will aid in understanding disease progression and developing personalized therapies.
The VasCog-2-WSO criteria update provide operationalization and guidance on neuroimaging and fluid biomarkers for VCID diagnosis. This new standard aims to facilitate diagnostic consistency among clinicians and researchers worldwide.
Researchers have developed a miniaturized microscope capable of real-time, high-resolution imaging of brain activity in mice. The device uses a novel neural network to reconstruct images in 3D and is nearly the size of a grape.
The UTHealth Houston Novel Treatments for Acute Brain Injury Institute focuses on improving care for patients with acute brain injuries through research, clinical expertise, education, and community outreach. The institute aims to advance pharmaceutical and device therapies and train the next generation of neurocritical care experts.
Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.
A new study from the University of Turku found that AI systems can accurately evaluate social features from images and videos, comparable to human evaluations. The researchers compared AI's evaluations with those made by over 2,000 humans, showing that AI's results were consistently accurate.