Articles tagged with Neuroimaging
Adolescents who frequently prefer solitude show measurable differences in brain structure and function, with weaker connections and greater fragility in social circuits. Clinicians can help families recognize risks by spotting early patterns of persistent withdrawal, opening the door to strategies that may protect mental health.
Researchers developed a fiber-optic method to track Alzheimer's plaques in freely behaving mice, allowing for real-time monitoring and long-term tracking of pathological changes. The technique uses fluorescent dye to bind specifically to amyloid fibrils and provides a minimally invasive way to study disease progression.
Professor John O'Brien's research focuses on understanding the impact of electrical synapses and gap junction plasticity on the retina and other neurological functions. The study aims to identify proteins that control electrical synapse strength, shedding light on their role in human disorders such as autism and seizures.
A new study found that healthy habits such as optimism, good sleep, and social support are strongly linked to healthier brains. Study participants who reported the most protective factors had brains eight years younger than their chronological age, and their brains aged more slowly over time.
A $10-million grant from the Weston Family Foundation will fund a project at McGill University to discover new Alzheimer's biomarkers. The ultra-high-sensitivity whole body PET/CT scanner, Panorama GS, will aid in understanding disease progression and developing personalized therapies.
The VasCog-2-WSO criteria update provide operationalization and guidance on neuroimaging and fluid biomarkers for VCID diagnosis. This new standard aims to facilitate diagnostic consistency among clinicians and researchers worldwide.
Researchers have developed a miniaturized microscope capable of real-time, high-resolution imaging of brain activity in mice. The device uses a novel neural network to reconstruct images in 3D and is nearly the size of a grape.
The UTHealth Houston Novel Treatments for Acute Brain Injury Institute focuses on improving care for patients with acute brain injuries through research, clinical expertise, education, and community outreach. The institute aims to advance pharmaceutical and device therapies and train the next generation of neurocritical care experts.
Researchers developed a new method to correct for variations in brain imaging measurements, reducing bias and increasing the accuracy of studies on ADHD. The traveling-subject method demonstrated reduced measurement bias while maintaining sampling bias, revealing decreased brain volume in critical regions for cognitive functions.
A new study from the University of Turku found that AI systems can accurately evaluate social features from images and videos, comparable to human evaluations. The researchers compared AI's evaluations with those made by over 2,000 humans, showing that AI's results were consistently accurate.
Scientists have discovered that tiny brain vessels pulse to regulate blood flow through bursts of contraction and relaxation. The research reveals that these bursts originate from the walls of small arteries and spread through the vascular network in short intervals, providing insights into how the brain regulates its blood supply.
Researchers found neglected children had abnormalities in critical brain regions, including right corticospinal tract and superior longitudinal fasciculus, linked to behavioral difficulties. These findings provide objective markers for identifying children affected by neglect.
A study published by the American Psychological Association reveals that extreme liberals and conservatives exhibit similar brain responses to political content. The researchers used fMRI scans, skin conductance measures, and eye-tracking to analyze 44 participants with varying political ideologies and levels of extremism.
Despite long-held assumptions, a new study reveals that the brain's somatosensory cortex holds a stable 'body map' even after limb loss. The findings have significant implications for treating phantom limb pain and restoring sensation in prosthetic limbs via brain-computer interfaces.
The Fork It Fund has awarded $1 million to support a major initiative at Stevens INI, accelerating scientific discovery by making critical research data more accessible worldwide. GAAIN is a global data-sharing platform connecting Alzheimer's disease and dementia-related data repositories from around the world.
Researchers found that brain maps of the hand and lips remained consistent even after amputation, contradicting previous views of reorganization. This study has implications for treating phantom limb pain and controlling robotic replacement limbs via neural interfaces.
The TReNDS Center has received two new NIH-funded R01 grants aimed at tackling Alzheimer's disease progression and advancing multimodal brain imaging techniques in neuropsychiatric disorders. The center will develop flexible models to link data and uncover complex patterns in neuroimaging and genomics.
Scientists have successfully decoded inner speech using brain-computer interfaces (BCIs) with an accuracy rate of up to 74%. The BCI system can interpret neural activity related to thought processes, allowing individuals with severe paralysis or motor impairments to communicate more naturally and comfortably.
Researchers discovered a link between stomach rhythm and psychological well-being, finding stronger coordination is linked to higher levels of anxiety, depression, and stress. The study suggests the stomach's 'second brain' may play a crucial role in mental health diagnosis and treatment.
Researchers discovered a brain mechanism behind 'specific musical anhedonia,' where people experience no pleasure from music despite normal hearing and other experiences. Studies using the Barcelona Music Reward Questionnaire support this idea, showing reduced activity in the reward circuit when listening to music.
Researchers create breakthrough imaging system that shows sensory activity in real time, enabling them to distinguish between different sensations. The technique uses a genetically encoded voltage sensor to observe electrical signals from neurons and has major implications for treating chronic pain and sensory disorders.
Researchers aim to uncover how menopause and lifestyle factors shape brain aging in women during midlife. The three-year project will analyze MRI scans and health data from thousands of women worldwide to track changes in brain structure and connectivity.
Researchers at the Institute for Basic Science have discovered that excessive GABA produced by astrocytes impairs fear extinction in PTSD. A new brain-permeable drug called KDS2010 has reversed PTSD-like symptoms in mice, providing a promising therapeutic approach.
The largest neuroscience event will convene in San Diego from November 15-19, featuring over 10,000 presentations on various topics. Registered journalists will gain access to cutting-edge research, expert interviews, and press-only events.
Researchers explored neuroanatomy underlying social dominance in nonhuman primates, focusing on the uncinate fasciculus and its correlation with social dominance measures. The study found a significant correlation between this brain tract and social aggression, supporting human studies linking it to social dominance.
Researchers discovered a two-step mechanism where inhibitory neurons release nitric oxide to rapidly dilate blood vessels, followed by slower, localized vasodilation via astrocyte activation. This breakthrough sheds light on how neural signals are translated into blood volume changes in brain imaging.
A study published in Alzheimer's & Dementia found that regular opioid use is associated with a 20% increased risk of all-cause dementia and over 70% increased risk of dementia among those taking strong opioids. Regular opioid use was also linked to reduced brain volume, lower fluid intelligence, and higher risk of vascular dementia.
A NUS-led global study reveals that 30-minute functional MRI scans deliver up to 22% in cost savings while retaining or improving prediction accuracy. This finding could reshape how researchers design neuroscience and mental health studies, especially for hard-to-recruit populations.
Researchers at Stanford University have developed new technology to image brain waves, revealing three new types of brain activity. The ultra-sensitive optical instruments can detect signals of genetically engineered proteins and show neural activity across the majority of the mouse neocortex.
Researchers found that adults with autism perceive visual body information similarly to neurotypical adults, challenging long-standing assumptions about social difficulties in ASD. The study used fMRI to compare brain activity patterns in adults with autism and typically developing adults while viewing images of body parts.
A recent study using machine learning and computational modeling reveals that astrocytes play a more active role in brain function than previously thought. Astrocytes subtly modulate communication between neurons during synchronous brain activity, influencing network coordination and stability.
Research from Kyoto University found that continuing to play a musical instrument into old age preserves brain function and prevents atrophy in the putamen. Long-term practice showed no decline in verbal working memory performance or gray matter volume, while short-term practice improved memory function for four months.
A new study published in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging found that individuals with remitted depression show increased habenula activity and reduced connectivity between the habenula and dopamine-producing regions, suggesting a heightened sensitivity to negative cues. This suggests that even after recove...
A new study explores the connection between grip strength and psychosis, finding that impaired grip strength and well-being share common patterns of brain connectivity. The research provides a unifying brain circuit explanation for psychosis and identifies potential brain targets for new treatments.
Researchers suggest that brains reach a critical state to learn, remember, and think, which can be measured using fMRI technology. This framework offers a new perspective on neurological diseases like Alzheimer's, which disrupt the brain's ability to maintain criticality.
The Cirrus Resting State fMRI Software uses AI technology to rapidly map the brain and identify sensitive areas controlling critical functions. The technology, developed at WashU Medicine, enables more precise neurosurgeries with improved accuracy and accessibility for patients.
Researchers at the University of Missouri have developed a new imaging probe that can help surgeons accurately identify and remove aggressive brain tumors during operations. The tool, known as FA-ICG, uses near-infrared light to highlight tumor cells from within.
Researchers discovered that exploring environments can encode visual features, speeding up learning when tasks arise. The study found that unsupervised learning occurs even without specific goals or tasks.
A novel study in Biological Psychiatry highlights the layered and complex interactions between clinical symptoms and neurobiological sources of variation in depression. The research found that multiple brain profiles may manifest as the same clinical symptoms, supporting the presence of both one-to-one and many-to-one heterogeneity.
Bioengineering researchers at Harvard John A. Paulson School of Engineering and Applied Sciences developed a soft, thin, stretchable bioelectronic device that can be implanted into a tadpole embryo's neural plate, recording electrical activity from single brain cells with millisecond precision.
A study of 34 children found significant differences in basal ganglia volume between those exposed to prenatal Superstorm Sandy and those not exposed. The findings suggest that extreme heat may have amplified the risk of having a differently-sized basal ganglia.
Researchers found that passionate fans show more activity in the dorsal medial prefrontal cortex during offensive faceoff opportunities, indicating emotional involvement and evaluative thinking. The study used functional near-infrared spectroscopy to track brain activity in 20 participants watching a professional European ice hockey game.
Researchers at Aarhus University and University of Oxford used a novel neuroimaging method to show that the brain dynamically reconfigures its organization in response to auditory stimulation. This discovery opens new possibilities for studying brain responses to music, consciousness, and other phenomena.
Researchers have developed CaliAli, an advanced analytical framework that aligns calcium imaging data across multiple sessions, allowing for the continuous tracking of individual neurons. This breakthrough enables long-term brain activity studies and advances understanding of memory formation, retention, and neurological diseases.
A new technology enables early and precise disease detection by capturing brain activity with an extremely thin, flexible imager smaller than an eyelash. The device can image mouse brain tissue for structural and functional imaging of brain activity.
Researchers discovered that oscillatory activity in two brain regions plays a crucial role in integrating auditory and visual information during memory recall. The study used movie clips with synchronized or asynchronous speech sounds and lip movements to explore this phenomenon.
A new USC-led study found a significant link between type 2 diabetes and cortical thickness in older adults from various populations. The researchers discovered that individuals with T2DM exhibited thinner cortex, particularly in temporal and parietal regions critical for memory and cognitive function.
Researchers have identified the medial prefrontal cortex (mPFC) as the basis of emotional inference in animals and humans. In a study published in Nature, Xiaowei Gu and Joshua Johansen found that rats can learn inferred emotions by associating a neutral stimulus with an unpleasant experience.
Researchers found that hormone fluctuations during the mouse estrous cycle impact the shape and behavior of hippocampal neurons. The study suggests that sex hormones influence cognitive functions like memory and learning.
A study published in Alzheimer's & Dementia found that learning one's Alzheimer's risk can decrease negative emotions like depression and anxiety, but also leads to decreased motivation for maintaining healthy lifestyle changes. Researchers emphasize the importance of personalized disclosure processes to sustain healthy behaviors.
A new microscopy method, LICONN, developed by ISTA scientists and Google Research, can reconstruct mammalian brain tissue with all synaptic connections between neurons. This technique uses standard light microscopes and hydrogel to achieve high resolution and opens up possibilities for visualizing complex molecular machinery.
A team of researchers has shown that it may be possible to diagnose Parkinson's disease years before it becomes untreatable by scanning people's brains with fMRI. The study used ultra-high field experimental MRI scanners and analyzed brain activity in response to sensory impairments such as loss of smell and visual deficits.
A study at Emory University revealed that five-year-olds have the brain system that supports map-based navigation, challenging the assumption that this cognitive ability develops until age 12. Children can recognize landmarks and navigate through a virtual town with remarkable accuracy.
A new brain atlas developed by researchers at Duke University will increase precision in measuring changes in brain structure, making it easier to share results. The tool, the Duke Mouse Brain Atlas, provides a detailed map of the entire mouse brain, from large structures down to individual cells and circuits.
Researchers developed promising α-synuclein PET tracers that can visualize protein aggregates in living patients, enabling earlier diagnosis and treatment monitoring. Tracers like [18F]C05-05 and [18F]ACI-12589 showed significant results in distinguishing synucleinopathies from healthy controls.
A new AI tool has been developed to predict the relapse of pediatric brain cancer with high accuracy, using temporal learning algorithms to analyze sequential brain scans. The tool achieved an accuracy of 75-89% in predicting recurrence, outperforming predictions based on single images.
A new study reveals promising progress toward predicting how patients with major depressive disorder will respond to antidepressant medications. Brain connectivity patterns were found to significantly improve predictions of treatment response across two large, independent clinical trials.
Researchers created a world's first micrometer-level 3D multimodal atlas integrating cranium, functional brain regions, cerebral vasculature, and invasive brain-computer interface devices. The study utilized mixed reality for interactive visualization, enabling intuitive exploration of brain-computer interfaces and brain tissues.
Researchers found that oxytocin receptors were more abundant in egalitarian lemur species, contributing to reduced aggression and increased harmony. The findings could shed light on the role of hormones in shaping behavior in humans and other animals.
A novel cannula delivery system allows repeated, nondisruptive delivery of imaging agents to the mouse brain during long-term multiphoton microscopy. This innovation enhances longitudinal studies on brain function, disease progression, and potential treatments.