Articles tagged with Neuroimaging
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers found human infants use 'helpless' period to pre-train brain, leading to rapid learning and high performance, similar to machine learning models. This study challenges classic explanation for infant helplessness and could inspire next gen AI models.
A recent study discovered a critical brain signal mediated by dopamine and its 'D2' receptors that plays a crucial role in timing actions. The research team used novel imaging techniques to observe this activity before self-timed presses, finding a gradual increase in brain signals about half a second prior.
A new microscopy system called mosTF enables fast and clear imaging of the living brain, improving tracking of rapid changes in neural circuit structure. The system outperforms traditional two-photon microscopy methods by eight times speed and four-fold signal clarity.
Researchers have used BARseq to map the brains of nine mice, tracing gene expression in the visual cortex. The results show that losing vision leads to changes in gene expression across neighboring cortical areas, highlighting the complex connections between brain regions.
A study by the University of Turku found that regular caffeine consumption reduces dopamine transporter binding in Parkinson's disease patients, but has no impact on symptoms or motor function. High caffeine intake may also complicate brain imaging results, suggesting a 24-hour caffeine-free period before diagnosis is recommended.
Researchers assessed brain imaging for minor, moderate, and major ischemic strokes to evaluate early direct oral anticoagulant initiation. The study found no difference in treatment effects or adverse event rates among infarct sizes.
A study led by the University of Turku has identified the brain network responsible for stuttering, which may lead to effective treatments. The research found that stuttering is associated with structural changes in a specific brain network involving the putamen, amygdala, and claustrum.
Researchers explore nanoparticle-based therapies to specifically target lymphatic metastasis in breast cancer, providing a promising solution for patient treatment. Nanoparticles deliver drugs directly to tumors, targeting cancer cells to destroy them or slow their growth, while also enhancing the immune response.
A new study found significant differences in brain development between autistic boys and girls, with autistic females showing a thicker cortex at age 3 and faster cortical thinning into middle childhood. The findings highlight the need for longitudinal studies that include both sexes to better understand sex-specific changes in autism.
A study published in Nature Communications found that sharp-wave ripples in the hippocampus are associated with vivid, imaginative self-generated thoughts and less pleasurable states. This link may have implications for understanding conditions such as autism, attention deficit disorder, and happiness/well-being.
Researchers are working to make publicly funded data collection in computed tomography widely available and understandable by diverse communities. The Non-Clinical Tomography Users Research Network aims to improve data handling across scientific disciplines and standardize data acquisition, handling, and sharing.
A recent study found that high cumulative BMI is associated with smaller brain volume, larger white matter lesions, and abnormal microstructural integrity in adults. Maintaining a healthy BMI below 26.2 kg/m² is suggested for better brain health.
A team of visionaries at the Carney Institute developed 3D-printed brain and spinal cord implants, revolutionizing surgical implantations and optical access. Bioluminescence imaging overcomes limitations of traditional fluorescent microscopy, providing unprecedented observation of neural and vascular activity.
Researchers are studying the early brain development of babies born to mothers with diabetes to understand the link between prenatal exposure and later childhood obesity. They aim to identify key differences in brain structure and function that may contribute to the increased risk of obesity.
FutureNeuro, a leading SFI Research Centre, is expanding its research programme with a focus on diagnostics, therapeutics, and digital health. The centre aims to develop precision diagnostics, future treatments, and systems using real-time health data.
A new study using AI technology analyzed MRI scans from 471 men and 560 women, revealing differences in brain organization at a cellular level. The findings highlight the need for diversity in neurological research and may offer new insights into how psychiatric and neurological disorders develop differently in men and women.
Researchers created a corticolimbic index tool that categorizes Alzheimer's disease into three subtypes based on brain changes. The study found demographic and clinical differences among sex, age at onset, and rate of cognitive decline.
A groundbreaking study found that areas of age-related damage in the brain relate to motor outcomes after a stroke, suggesting other factors are at play. White matter hyperintensities were associated with more severe motor impairment, independent of corticospinal tract damage.
A new atlas of early brain development has been created, allowing researchers to understand the genetic processes behind brain tumor formation in children. The study's findings may lead to new treatments for this rare but deadly disease.
Researchers have developed a novel rigid endoscope system for visible-to-OTN hyperspectral imaging, enabling non-destructive imaging and visualization of lesions in normal tissues. The system demonstrated high accuracy in classifying molecular vibration information of various targets with an OTN wavelength range.
A previously healthy man developed toxic leukoencephalopathy after inhaling fentanyl, leading to inflammation in the brain and potentially irreversible damage. Fortunately, he slowly recovered with wraparound treatment from a multidisciplinary team at OHSU.
Researchers developed an AI technique to estimate brain age based on EEG scans, making early screening for degenerative brain diseases more accessible. The technology uses machine learning to analyze brain waves and can be used as a low-cost screening tool for large numbers of people.
Researchers used a new brain mapping tool called BARseq to classify and map millions of neurons across nine mouse brains. They discovered that sensory inputs influence the cellular signatures of each brain region, leading to distinct 'signatures' akin to cellular ID cards.
A large-scale study revealed a profound link between dietary patterns and brain health, with a balanced diet associated with better mental health, superior cognitive functions and higher grey matter in the brain. The researchers suggest that gradual dietary modifications can lead to healthier food choices and improved wellbeing.
Researchers developed a new method to accelerate high-resolution ultrasound localization microscopy using deep learning, enabling faster and more accurate imaging of microvascular structures. The technique, called LOCA-ULM, improves spatial resolution and processing speed while maintaining sensitivity for functional imaging.
Researchers found that individuals from certain racial and ethnic groups are less likely to be eligible for Alzheimer's disease clinical trials due to lower amyloid levels at early stages of the disease. Amyloid buildup in the brain varies across different populations, contributing to underrepresentation in clinical trials.
Researchers aim to understand mechanisms behind high ADRD rates among MENA immigrants, a growing demographic. The study will investigate daily living, stress, genetics, brain health, and cognitive ability, using MRI-based imaging and cognitive assessments.
Researchers from SGH and NNI found side-to-side differences in the corticoreticular pathway of patients with AIS, which may lead to better diagnosis and treatment options. The study's findings suggest that scoliosis is fundamentally related to brain and spinal cord interactions.
Researchers found that watching sports fosters a sense of community and belonging, while triggering activation in the brain's reward circuits. Regular sports viewing may also induce changes in brain structures, leading to long-term benefits for individuals.
Researchers at NIH developed a novel AI-based method called P-GAN to improve next-generation imaging of cells in the retina. The technique reduces imaging acquisition and processing time by 100-fold, yielding greater contrast and improving image quality.
Researchers at Janelia Research Campus have released Kilosort4, an updated version of the popular spike-sorting software that requires less manual work and is more accurate. The new software improves processing and allows for easier use, making it indispensable for neuroscientists worldwide.
A new bioluminescence imaging technique allows for real-time monitoring of oxygen concentration in the brain, revealing previously undetected areas of temporary hypoxia. The method enables researchers to study diseases associated with hypoxia, such as Alzheimer's and vascular dementia.
A new bioluminescence imaging technique allows researchers to observe oxygen movement in the brains of mice in real-time, providing insights into diseases such as Alzheimer's and strokes. The method reveals that small areas of the brain, called 'hypoxic pockets,' can be denied oxygen for brief periods, increasing risk for these diseases.
Researchers discovered changes to blood vessels in the brain that can increase stroke and dementia risk are common in people with heart conditions. The study confirms heart disease as a main cause of these changes, highlighting the importance of imaging tests to guide safer treatment choices.
A neuroimaging study found no significant differences in brain structure or function between individuals reporting anomalous health incidents and matched control participants. The researchers aimed to investigate the neural basis of these incidents among US government personnel stationed internationally.
Researchers developed a custom-built, low-cost mesoscope that can adapt to different neuroimaging experiments in live mice and rats. The system offers excellent spatial and temporal resolutions, achieved through its reversible tandem lens configuration, which enables flexible experimentation.
Researchers have developed a new method to trigger and image seizures in epilepsy patients, allowing for real-time data collection to tailor epilepsy surgery. This method is clinically feasible, convenient, and spares resources, providing valuable information for successful surgeries.
A study published by the University of Florida suggests a connection between elevated amyloid blood levels and subtle brain microstructural changes in individuals without dementia. Researchers used diffusion MRI to detect free-water in the brain, revealing associations with structural abnormalities even when PET scans were negative.
Researchers used mass spectrometry imaging and single-cell metabolomics with deep learning to create 3D molecular maps of the brain, enabling a better understanding of chemical interactions within brain tissue. This breakthrough could help address currently intractable neurological diseases.
A new study from Drexel University's Creativity Research Lab reveals that the creative flow state involves two key factors: extensive experience and release of control. High-experience musicians experienced flow more often and intensely than low-experience musicians, suggesting expertise enables flow.
Researchers found that faulty mtDNA replication causes mitochondria to leak genetic material, triggering an immune response and leading to disease. By targeting this process, doctors may develop therapies to prevent harmful inflammation.
Researchers decode underlying mechanisms of DCM, hippocampal neurotoxicity, and dysbiosis mediated AD progression using mass spectrometry imaging. The studies found metabolic changes in DCM rat hearts and regulation of CYPs in the hippocampus, providing new perspectives on treatment strategies.
Scientists have discovered that the bat brainstem processes echolocation and communication calls differently, with a stronger response to less frequent calls due to better neural synchronization. The findings may also be relevant to medical applications in humans, such as understanding diseases like ADHD or schizophrenia.
A team of researchers used deep brain stimulation to localize disrupted neural pathways in patients with Parkinson's disease, dystonia, OCD, and Tourette's syndrome. The study identified specific brain circuits associated with each disorder, revealing overlapping malfunctions that suggest a complex network of brain dysfunctions.
A new method for phase-modulated stimulated Raman scattering tomography enables rapid, label-free 3D chemical imaging of live cells and tissues. This technique improves lateral resolution and imaging depth compared to conventional methods.
Researchers developed a toolkit to translate neuroimaging data into audiovisual representations, enabling scientists to explore brain activity patterns in real time. The tool uses piano sounds for neural activity and violin sounds for blood flow, allowing viewers to discern coupled relationships between the two.
Researchers developed a high-speed modulation system combining digital display with super-resolution imaging, significantly improving lateral and axial resolution. This enables detailed study of subcellular structures in animal cells and plant ultrastructures, paving the way for future biological discoveries.
Researchers at Mount Sinai Health System developed a novel protocol for rapid diagnosis of eye stroke, improving outcomes and preserving vision. The protocol uses high-resolution retinal imaging in emergency rooms, along with remote consultation, to confirm diagnosis and expedite care.
The study reveals that the superior colliculus is vital in the transition from seeing individual flashes to smooth motion, and may be a key component in creating the continuity illusion. Different methods of measuring the Flicker Fusion Frequency threshold suggest other parts of the brain also play a role in this process.
Researchers at ETH Zurich have developed a new magnetic resonance imaging (MRI) procedure that maps the condition of myelin sheaths in the central nervous system more accurately. This breakthrough technology has the potential to facilitate early MS diagnosis and monitoring, as well as the development of new drugs for the disease.
Researchers developed an AI algorithm to analyze brain scans and clinical data, predicting treatment response with 8-week accuracy.
Researchers discuss recent advances in brain mapping, emphasizing the need to establish precise neuromodulation paradigms based on individual characteristics. Individualized brain mapping methods have evolved from manual labeling to staining techniques across multiple subjects.
A team of scientists from the Beckman Institute has received a $3 million grant to develop diagnostic tools and imaging agents for the early detection of Alzheimer's disease. They will use a combination of PET and MRI scans to target smaller beta-amyloid peptides and other signs of neuroinflammation and oxidative stress.
The Cognitive Neuroscience Society Conference in Toronto will explore the nature of thought and cognition. Registered press members will have access to scientific talks, posters, and receptions.
A new American Heart Association scientific statement emphasizes the need for increased awareness of cerebral venous thrombosis (CVT) to facilitate prompt medical treatment. The statement updates guidelines for diagnosing and managing CVT, focusing on advancements in treatment approaches.
Researchers have identified a network of lymphatic vessels at the back of the nose as a major hub for CSF outflow to deep cervical lymph nodes. This discovery has significant implications for understanding and treating conditions related to impaired CSF drainage, such as Alzheimer's disease.
Researchers developed a novel hybrid approach combining traditional mathematical methods and cutting-edge machine learning to improve EIT analysis of building structures. The new method, called AND, reduces errors in reconstructing foreign objects' position and size compared to conventional EIT methods.
Researchers developed a new imaging technique to visualize the tumor microenvironment of glioblastoma, revealing insights into its pathology. The technique uses PET imaging with Carbon-11 acetate, tracking reactive astrocytes and distinguishing them from tumor cells.
A new transparent brain implant has been developed to read deep neural activity from the surface, providing a step closer to building a minimally invasive brain-computer interface. The technology enables high-resolution data about deep neural activity by using recordings from the brain surface and correlating them with calcium spikes i...
Ashok Veeraraghavan, a Rice University professor, has won the Edith and Peter O'Donnell Award in Engineering from the Texas Academy of Medicine, Engineering, Science and Technology. His research focuses on making invisible objects visible through imaging technology that tackles challenges beyond current technologies.