The SynGAP Research Fund has awarded grants to Dr. Clement Chow to advance therapeutic development for SYNGAP1-Related Disorders. His research uses drug repurposing to identify compounds like N-acetyl-L-leucine as potential treatments.
Dr. Bonnie W. Ramsey is recognized for her significant contributions to advancing child health and the profession of pediatrics. Her work on cystic fibrosis has dramatically improved life expectancy for children with the disease.
A new multi-specialty guidance provides clarity on the usage of GLP-1 receptor agonists before elective surgery and gastrointestinal endoscopies. For most patients, these medications can be safely continued, but individual risk factors for complications should be assessed prior to surgery.
Researchers will explore the role of exosomes in delivering regenerative compounds, while also investigating olfactory receptors' unexpected functions in skin health. The conference aims to slow or reverse skin aging through novel approaches to mitochondrial function and microbiota balance.
Baise's research has spanned earthquake site response, liquefaction, site characterization, regional wave propagation, ground motions models and earthquake damage assessment. She uses data-driven approaches to learn from observational data and was an early adopter of machine learning methods in model development.
University of Texas at Dallas researchers have designed a 3D-printed femur that can help doctors prepare for surgeries and develop treatments for bone tumors. The bone replica is made of polylactic acid, a bio-based polymer, and performed as well as a human femur in biomechanical tests.
Ekaterina Zhuravskaya, professor of the Paris School of Economics, wins the award for her significant contributions to understanding institutions and media economics. Vladimir Vapnik, professor of Columbia University, receives the award for his fundamental contributions to statistical learning theory and Support Vector Machines.
Dr. Andero Galí's groundbreaking research connects mouse and human fear responses, using techniques like in vivo calcium imaging in mice and human fear response studies. His approach aims to create a more comprehensive understanding of the human brain by breaking down traditional barriers between animal and human studies.
Research by Marieke Wieringa found that people are more inclined to believe a robot is in pain if it's manipulated to experience emotional distress. This can lead to increased pity and decreased willingness to mistreat the robot.
The Berlin Declaration aims to achieve carbon neutrality through basic research and international cooperation. The declaration highlights the importance of developing effective measures to reduce CO2 emissions in all sectors, including energy and industry.
A new law change proposal aims to provide families of missing persons with an opportunity for closure through burial, rather than cremation. The proposal, backed by expert research, would require DNA sampling before burial to confirm identity and enable family members to make decisions about the body.
The upgrade enhances research security and compliance, aiding institutions in risk identification and documentation. It also facilitates collaborations within institutions through its dashboard app.
A new clinical guidance from the American Society of Anesthesiologists recommends continuing GLP-1 drugs for patients with diabetes and weight loss before elective surgery, except for those at highest risk for gastrointestinal problems. Patients at high risk should follow a liquid diet or other measures to minimize risks.
The Dingus family donation supports the launch of the Earth and Planetary Opportunities in Research (EXPLORE) program, which provides hands-on experience for undergraduates in research projects related to Earth and space. The fund also enables fellowships for graduate students working in environmental science and sustainability.
Prof. Tamar Saguy, a full professor at Reichman University's School of Psychology, has been recognized for her groundbreaking research on reconciliation processes between groups. Her work highlights the importance of addressing power imbalances in dialogue initiatives and proposes effective strategies to promote social change.
Chris Van de Walle, a distinguished professor at UCSB, has been awarded the American Physical Society's 2025 Aneesur Rahman Prize for Computational Physics. He was recognized for his development and application of first-principles methods to compute structural, electronic, and optoelectronic properties of point defects and interfaces.
The Whales & Arctic Vessels Project will research how often and where whales encounter vessels in the high Arctic, addressing a largely unexplored area of marine life. The collaboration aims to gather critical data to inform management strategies and promote global awareness for Arctic whale conservation.
Professor Vicki Clifton's team has identified a sex-specific variant of the glucocorticoid receptor isoform that enhances inflammation in the placenta during maternal stress. This finding could transform how clinicians approach pregnancy complications and neonatal care, leading to targeted interventions based on placental function.
The study found that brain responds rapidly to face-like features, even in ambiguous black-and-white stimuli. Face-likeness affects unconscious processing, and images with high degree of facial likeness are detected faster than those without.
A Colorado School of Public Health study reveals that gender affirming care patients experience disproportionately high levels of trauma, homelessness, and housing insecurity. Commercial insurance covers most treatments, but access to care varies by region.
Researchers have discovered a novel strain of cyanobacteria that can grow rapidly in high-CO2 environments, sink in water, and produce valuable commodities. The 'Chonkus' strain has traits useful for biologically-based carbon sequestration and bioproduction.
The University of Missouri's College of Education and Human Development is giving free online training and coaching to 110 middle school teachers in rural Missouri. The goal is to create a safe learning environment, with the potential to reduce stressors for teachers and improve student engagement.
Researchers developed a method to assess which patients with metastatic triple-negative breast cancer can benefit from immunotherapy. The tool uses predictive biomarkers and machine learning-based approaches to identify patients who are likely to respond to treatment.
Researchers have developed an innovative framework combining remote sensing and mobile phone data to create highly accurate monthly population maps at fine resolutions, providing detailed insights for urban planning and emergency response. The approach leverages building area, vegetation cover, and machine learning techniques to captur...
A recent study by CU Anschutz scientists found that an ancient gene mutation among First Nations inhabitants of Oceania may make them more susceptible to certain infectious diseases. The allele, KIR3DLI*114, is widespread and unique to Oceania, with up to 30% of individuals carrying it.
Researchers have identified 44 genetic regions associated with metabolite levels in the body, which can influence cardiovascular risk. The study found a potential molecular mechanism by which six genetic loci are linked to cardiovascular risk through the metabolites they regulate.
The University of Kansas and Avium will develop new catalysts and technologies to improve the efficiency and reliability of green hydrogen production. The goal is to make clean hydrogen more affordable and support the transition to a clean-energy future.
Researchers gather seven years of data on sucker spawning migrations using observations from trained volunteers. The data reveals that temperature is the primary trigger for sucker spawning migration, which can help inform conservation strategies in light of a changing climate.
The Lancet's Countdown report reveals record-breaking human costs of climate change, including heat-related deaths increasing by 167% globally in 2023. The report calls for trillions of dollars spent on fossil fuels to be redirected towards protecting people's health and lives.
A new study provides deeper understanding of Myotonic Dystrophy Type 1 (DM1) by revealing an unexpected link between the cardiac condition and SCN5A protein. The research found that reducing fetal SCN5A expression did not correct heart defects, suggesting alternative approaches may be needed to address the condition.
Researchers identified key compounds that distinguish beer from wine aromas, enabling the creation of more flavorful, non-alcoholic substitutes. Stronger fruity aromas made drinks smell more like wine, while scented compounds played a bigger role in beer versus wine-like aroma perception.
Researchers at UC Irvine have discovered a powerful link between olfactory loss and inflammation in various medical conditions, including Alzheimer's and Parkinson's diseases. Scent therapy may offer a novel approach to mitigate symptoms and prevent disease onset.
A KAIST team created a face-conforming LED mask with improved efficacy in skin rejuvenation. The FSLED mask demonstrated a 340% improvement in deep skin elasticity compared to conventional masks, showing significant benefits for anti-aging treatment.
A USTC team led by Researcher LIU Ji unveiled an adrenal-independent pathway, the hypothalamus-sympathetic-liver (HSL) axis, to mediate stress-induced glucose release. This new pathway regulates glucose homeostasis and provides potential therapeutic targets for stress-related metabolic disorders.
Researchers explored how future changes in the North Water Polynya could impact marine communities. Changes in plankton and fish populations were found to have significant effects on the entire ecosystem. Polar bear numbers are projected to halve due to declining phytoplankton and copepods.
A recent study published in Antiquity has uncovered over 6,500 pre-Hispanic structures, including a large, previously unknown city with iconic stone pyramids. The research used lidar technology to survey 50 square miles of land in Campeche, Mexico, revealing a more complex and varied Maya landscape than previously thought.
A randomized trial found early TAVR to be safe and effective for patients with asymptomatic severe AS, reducing the risk of composite endpoints and favorable health status outcomes. Patients who received early TAVR had better left-ventricular and left-atrial health compared to those on clinical surveillance.
A study found that using an orbital atherectomy device to remove calcium from blocked coronary arteries before stenting procedures did not improve patient outcomes. The device was used on patients with moderately severe calcification, rather than extreme cases, and did not show significant benefits.
Researchers developed a new approach for harvesting and storing solar energy efficiently using molecular solar energy storage systems. The system increases solar energy storage efficiency by more than one order of magnitude.
Researchers found that Weddell seals strategically conduct extreme dives earlier in the day to maximize their oxygen stores and foraging success. By avoiding midday dives, the seals can spend more time underwater, taking advantage of high-light conditions, which is ideal for visual hunting.
A study by Anglia Ruskin University found that rising inflation and bank rates led to increased discrimination against Black people in the UK, resulting in poorer general and mental health outcomes. The study highlights the disproportionate impact of the cost-of-living crisis on minority groups.
Researchers at MIT have designed tiny particles that can be implanted at a tumor site, delivering heat and chemotherapy to treat cancer. The treatment approach has been shown to completely eliminate tumors in most mice and prolong their survival.
A comprehensive review of global evidence highlights the devastating effects of family violence on mental and physical well-being. The study, involving over 3 million individuals, reveals a strong connection between family violence and various adverse health outcomes.
A study found that levels of toxic chemicals in people's bodies decreased both in California and nationwide following the listing of over 850 chemicals under Proposition 65. This decline suggests that the law has led to widespread reformulation of products, reducing exposure to harmful substances.
A new study by UCLA Health reveals that standard medical record surveillance methods miss youth with suicidal thoughts and behaviors in children, boys, and Black and Hispanic youths. Machine learning algorithms improved detection rates when incorporating additional data from visit notes.
Researchers develop transcranial ultrasound stimulation (TUS) as a non-invasive therapy for brain-related issues, with potential for personalized treatments. A 'search and rescue tool' for the brain, TUS enables precise targeting of specific areas before treatment.
A new £5.5 million research unit will strengthen existing UK systems to measure environmental exposures and understand how they affect the body. The Health Protection Research Unit in Chemical Threats and Hazards aims to develop new technologies to detect chemicals in emergency situations.
The TAVR UNLOAD study found that transcatheter aortic valve replacement did not significantly affect the primary composite endpoint in patients with systolic heart failure and moderate aortic stenosis. However, TAVR improved quality of life compared to clinical AS surveillance.
Research suggests that just one or two sessions of physical activity per week can lower the risk of cognitive decline and dementia, which may be more convenient for busy people than regular exercise. The 'weekend warrior' pattern was found to be associated with a 25% lower risk of cognitive decline compared to non-exercisers.
A large observational study found associations between cannabis use and brain structure and function changes in later life. However, genetic analysis using Mendelian randomization suggests that these associations may not be causal, with possible explanations including unmeasured variables or differences in statistical power.
The Prevention Research Center of Michigan is expanding community-academic partnerships to tackle vacant lots and create safer neighborhoods. The project aims to reduce crime, boost social capital, and increase physical activity opportunities for African American and Latino adults in Flint.
Researchers found that glycans attached to glycosylation enzymes' lectin domains inhibit the enzymes' activity, leading to self-regulation of their own biosynthesis. This unique mechanism sheds light on how glycosylation enzymes choose their substrate proteins in cells.
Researchers developed a new biocompatible sensor substrate using Ag nanoislands protected with column-structured silica, increasing fluorescence and Raman signals by 10 million times. The technique enables non-invasive monitoring of biological processes without disrupting cell function or causing damage.
A study published in the British Journal of Anaesthesia found that using a single syringe pump for induction and maintenance of anesthesia reduces propofol waste by 30-50%. This eco-friendly approach can also save hospitals money by reducing the number of propofol vials needed. The researchers analyzed data from over 300 surgeries and ...
Brachycephalus dacnis is the seventh species of flea toad identified in the genus Brachycephalus. The study published by a group at the State University of Campinas provides detailed information about its anatomy, skeleton, and internal organs.
Researchers investigated the molecular mechanism of Fuzi's cardioprotective effects on heart failure. Fuzi water decoction and alkaloids were found to regulate apoptosis, proliferation, and anti-fibrosis in heart failure models, with ABC transporters potentially being a key pathway for their action.
Researchers developed a new surveillance technique to track COVID-19 diversity using genomic data, predicting variant emergence with high accuracy. The software can forewarn public health officials of impending outbreaks, enabling timely responses and more effective disease monitoring.
Researchers propose a comprehensive biomarker-based approach to assess cardiovascular risk by combining markers of chronic inflammation with cardiac health indicators. This approach reveals the significant impact of aging-related inflammation, or 'inflammaging,' on heart health and opens new avenues for targeted interventions.
Researchers at the University of Ottawa have created a new type of contrast agent using gold nanoparticles to improve doctors' ability to diagnose heart conditions. The new agent, AuSC@(13FS)2, showed strong binding to P-selectin and improved IV-OCT imaging in rats with inflamed blood vessels.
A team of researchers from Northwestern University has developed a novel machine-learning approach to accurately predict pneumonia outcomes by analyzing electronic health records. The study identifies five distinct clinical states in pneumonia, three of which are strongly associated with disease outcomes and two that can help physician...
Researchers developed a new imaging analysis technique combining biomarkers and tumor architecture to create a 'fingerprint' for each patient, enabling precise prognosis and treatment response. The method identified two previously undetected groups of patients, with exceptional good or bad prognoses.
A new study by the Barcelona Institute for Global Health found that more than half of European heat-related deaths in summer 2022 were related to human-induced climate change. The research showed a higher number of heat-related deaths attributed to climate change among women and people aged 80 and over.
A team of researchers has unveiled a spectacular new fossil arthropod named Lomankus edgecombei, preserved entirely in fool's gold. The specimen belongs to a group called megacheirans, which were thought to be extinct during the Ordovician Period.
A new open-access database, LitChemPlast, has compiled over 3,500 substances measured in plastic products across 47,000 samples. The study highlights substantial knowledge gaps, including contamination of recycled plastics with hazardous substances and limited regional coverage in low- and middle-income countries.
Scientists used photon-counting CT scanner to track changes in protein expression and cartilage degradation in animal model. The approach revealed evidence of osteoarthritis long before clinical symptoms develop, offering potential for early diagnosis and monitoring.
Researchers analyzed data from air quality monitoring stations in Spain and Portugal to reconstruct PM10 concentrations during extreme dust events. The study found that concentrations reached up to 5000 micrograms per cubic meter in the Canary Islands and exceeded EU standards.
A new method, MLP-Mixer and Mixture of Expert model, predicts lithium-ion battery lifespan with high accuracy by handling varying contributions of different time steps. The proposed model outperforms existing methods on NASA and CALCE public datasets, providing reliable RUL predictions.
Researchers found that using a multi-step strategy with less-invasive devices can identify patients with Barrett's oesophagus before an endoscopy. This approach is promising for cost-effective screening, which could lead to earlier diagnosis and treatment of oesophageal cancer.
Researchers used a classical computer and mathematical models to outperform a quantum computer on a task involving a two-dimensional quantum system of flipping magnets. The system displayed a behavior known as confinement, which had previously been seen only in one-dimensional systems.
The PROTECTED trial found no significant impact of cerebral embolic protection on periprocedural stroke risk, but suggests a trend towards greater stroke reduction in US cohorts compared to outside the US
Researchers identified six novel genes associated with a significant increase in cancer risk, including BIK for prostate cancer, ATG12 for colorectal cancer, and CMTR2 for lung and melanoma. Loss of AURKB was found to protect against any cancer type, while loss of PPP1R15A was linked to a 53% lower risk of breast cancer.
A large multicentre cohort study has identified a specific gene linked to human pain and found that low insulin levels, depression, and alcohol use disorder are causally linked to neuropathic pain in people with diabetes. This research may lead to the development of new treatments for this devastating condition.
Researchers at UCLA developed a new type of imaging technology that forms images in only one direction, enabling efficient and compact methods for asymmetric visual information processing and communication. The technology works exceptionally well under partially coherent light, achieving high-quality imaging with high power efficiency.
Researchers at Osaka Metropolitan University have discovered a key protein involved in transporting boron into plant cells. The protein complex, containing KNS3 and its homologs, facilitates the movement of boric acid channels from endoplasmic reticulum to plasma membrane.
Researchers discovered a new type of jeilongvirus in a Florida mouse, which can infect humans and non-human primates, posing a risk of serious illness. The virus is genetically distinct from others and can cause disease in various species.
The new guidelines aim to unify the diagnosis and management of children and adults with Still's disease, previously separated by age. The recommendations emphasize shared decision-making between patients and treating teams, and prioritize achieving drug-free remission through treat-to-target strategies.
Research in Physics of Fluids reveals that smokers seated farther from ventilation inlets experience lower levels of pollution. Body heat causes more absorption of cigarette pollution, suggesting empty spaces are the best to choose.
Researchers have developed a new field called stochastic thermodynamics, which provides tools to investigate and quantify the energetics of computational systems far from thermal equilibrium. This can help minimize heat losses and optimize energy efficiency in computing.
Research finds that sustained engagement in regular physical activity before and after a dementia diagnosis is associated with the greatest reduction in risk of death, regardless of dementia type. Maintaining an exercise routine or starting new activities also reduces mortality risk, with higher levels associated with greater reductions.
A new study published in npj Complexity found that the 2020 U.S. election drew online hate communities closer together, inciting new hate content around immigration, ethnicity, and antisemitism. The research team developed an 'online telescope' to map the online hate universe at unprecedented scale and resolution.
A new study reveals that Britain's earliest brass bands were founded by military musicians in the 1810s, contradicting the long-held assumption that they emerged with industrial communities. The research, published in The Historical Journal, shows that regimental bands first experimented with all-brass formats after the Napoleonic Wars.
Researchers identified three long noncoding RNAs associated with worse outcomes in colorectal cancer patients, potentially serving as prognostic markers. The study's findings could enable doctors to separate high-risk patients from those at low risk of disease recurrence, leading to more effective treatment strategies.
A new study from Chalmers University of Technology presents a technology that can destroy bacteria on implants using gold nanorods and near-infrared light. The method heats up the gold rods, killing bacteria without damaging surrounding tissue.
Researchers from Universitatsklinikum Bonn found that tiny eye movements and photoreceptor density in the fovea contribute to sharp vision. The study used high-resolution imaging and micro-psychophysics to demonstrate how finely tuned eye movements provide optimal sampling by cones, leading to better visual acuity.
Researchers used x-ray microtomography to discover and describe 12 new weevil species from Japan, Malaysia, Vietnam, and Taiwan. The technique revealed significant morphological differences between species, which cannot be easily observed using other methods.
Research identifies three clinical subtypes of schizophrenia, differing between subjective and objective social cognitive difficulties, providing a guide for targeted interventions. The study aims to improve individualized treatment approaches for patients with schizophrenia.
A study found that people's choices between safe and risky options are influenced by their perception of an observer's opinion. After initial biases, participants learned to correctly predict their partners' choices and adjusted their behavior accordingly.
A study by Osaka University reveals that Japanese consumers value transparency in AI assistants, compromising on performance for greater clarity. Environmental sustainability is also a consideration, but remains secondary to cost and performance.
Researchers analyzed Twitter posts and Google searches from 2016-2020 to identify seasonal allergy patterns across the US. They found a strong national pulse of allergy symptoms in March-May, with significant regional variations.
A new study suggests that boosting T-regulatory cells may improve the chance of healthy pregnancy and reduce miscarriage risk. Researchers found that treatment with interleukin-2 and antibodies targeting these cells improved pregnancy outcomes in mice, reducing miscarriage rates from 30% to 11%.
Approximately half of Russian adults back the Ukraine war due to loyalty to Putin and his government. The study suggests that misinformation plays a significant role in shaping public opinion on the conflict.
Researchers investigate universe expansion, Big Bang, black holes, and dark energy using a time-reversal model. They propose an explanation for the Big Bang and explore interior structure of black holes.
Researchers have developed a laboratory system that can precisely control and study cell division mechanisms in real-time. By manipulating the phosphorylation state of the protein PRC1, they discovered that large-scale transitions in cytoskeleton organization can be induced in just a few minutes.
A recent study found that over 90% of Mexican consumers would be willing to pay a premium of up to 73% for non-genetically modified products, including chicken, eggs, and tortillas. The ban on genetically modified corn could have significant impacts on US farmers who rely heavily on Mexico as their second-largest importer.
Researchers designed a multipass cell with dense spot patterns to enhance laser absorption spectroscopy gas sensors. The new design achieved high sensitivity and selectivity, enabling the detection of methane at low levels.
This study explores the radioprotective effects of Licochalcone B on radiation-induced cell damage and mortality in mice. Lico B significantly improves antioxidant levels, reduces DNA damage, and lowers inflammatory factors.
Researchers identify two robust social norms that protect cooperative behavior from defector invasions and reputation costs. These norms shield justified defection, allowing cooperation to persist, while others negatively evaluate unjustified cooperation, excluding free-riders.
A Dartmouth study has quantified the global economic fallout of El Niño, finding it costs the economy $4.1 trillion and $5.7 trillion in the half-decade after each event. The study's findings are included in the 10 New Insights in Climate Science report ahead of COP29.
A new noninvasive test using a device called the Cytophone can detect malaria without taking a single drop of blood, showing 90% sensitivity and 69% specificity in tests with adult patients diagnosed with symptomatic malaria. The technology has potential to improve detection of malaria cases and help initiate treatment.
Fossil hunters have identified a new species of ancient bug, Lomankus edgecombei, which spent 450 million years covered in pyrite, or fool's gold. The discovery sheds light on the evolution of life in oceans during this period and indicates that Megacheirans continued to evolve longer than previously thought.
A new study published in the journal Aging & Mental Health found that people with more positive expectations of aging tend to report less frequent cognitive problems and are less likely to perceive a decline in their cognitive performance over time. Researchers suggest that modifying older adults' aging expectations could support healt...
Researchers confirm beehive fences as highly effective in reducing human-elephant conflict, deterring 76-86.3% of elephants from raiding crops during peak seasons. However, ongoing habitat degradation and droughts may compromise the long-term effectiveness of this nature-based solution.
Scientists used acoustic mapping technique to track vulnerable capelin species and observe massive predation event involving Atlantic cod. The study revealed that as climate change causes Arctic ice sheet to retreat, capelin will be more stressed and vulnerable to natural predation events.
A study led by CU researchers reveals that bedside interdisciplinary rounds build trust between patients and healthcare providers and within teams, leading to improved care experiences. Patients reported positive feelings about being involved in their care plans, while healthcare professionals reported respect and trust among colleagues.
Florida Atlantic University's Southeast National Marine Renewable Energy Center is establishing a blue energy hub to develop and test ocean current energy technologies. The project aims to improve the nation's competitiveness in marine energy technology and create jobs.
Researchers from Osaka University have developed tough biodegradable plastics with movable cyclodextrin crosslinks, which improve both durability and degradation capabilities. The new polymers can be broken down by enzymes into useful precursor molecules, reducing waste generation.
Researchers found that human histones have antimicrobial activity against bacteria, including Pseudomonas aeruginosa biofilms, reducing bacterial mass by up to 70% and survival time in infected larvae by 50%. The study suggests using histones or parts of these proteins as a promising alternative to combat acute and chronic infections.
Researchers analyzed correlations between fruit fly and human data to identify key metabolites impacting lifespan. Threonine was found to extend lifespan in flies and show promise as a therapeutic target for aging interventions.
Emerging technology allows long-term storage of human organs, addressing severe time constraints that limit organ viability. New governance and legal rules are needed to guide this application, including oversight from the FDA and ethics guidance on organ storage.
The study identified 97 potential therapeutic targets for SFJD, with 27 key targets involved in antiviral, anti-inflammatory, and immune regulation effects. Molecular docking results showed strong interactions between core active ingredients and these targets.
A recent study by Flinders University researchers challenged the common assumption that autistic adults are more prone to criminal exploitation due to difficulties in reading others' intentions. The study found that verbal intelligence and Theory of Mind were critical factors influencing vulnerability to crime, not autism diagnosis.
A new study found that early aortic valve intervention in patients with asymptomatic severe aortic stenosis and myocardial fibrosis did not reduce the incidence of all-cause death or unplanned aortic stenosis hospitalization. However, it did show benefits in reducing emergency hospitalizations and preventing symptom development.
Researchers found that thalattosuchian sinuses reduced during semi-aquatic phases and then diminished further as they became fully aquatic. This allowed them to develop extracranial sinuses, which might have helped drain salt glands and alleviate 'encrustation' problems.
A new study reveals that naturally occurring iron minerals can oxidise arsenite, making it less harmful to humans. The breakthrough has the potential to improve water and food safety globally, particularly in regions with high levels of arsenic pollution.
A remarkable clinical and metabolic response is reported in a metastatic BRAF V600E-mutated glomangiosarcoma treated with encorafenib and binimetinib. The combination of BRAF and MEK inhibitors achieves a long-lasting complete morpho-metabolic response in the patient.
The US Department of Defense has awarded $514,000 to study the efficacy of gene editors in treating Duchenne Muscular Dystrophy. Researchers will explore non-viral options for delivering gene therapy through 'self-delivering' gene editors, aiming to improve safety and efficacy.
Researchers at Seoul National University have developed ultra-low power neuromorphic hardware capable of performing AI computations with significant accuracy and efficiency. The technology relies on hybrid organic-inorganic materials and enables uniform ion movement across the surface, leading to high-performance neuromorphic devices.
Researchers discovered five distinct grain boundary structures composed of different arrangements of icosahedral cage units, enabling dense packing of iron atoms. The formation of these quasicrystalline-like phases can be used to tailor material behavior and make materials more resilient against degradation processes.
A systematic review found that exposure to social media posts depicting ideal muscular male bodies is directly linked to a negative body image and greater odds of resorting to anabolic-androgenic steroid use. Men are also under pressure to be physically strong, which is intrinsically linked to masculinity.
A new study reveals that couples living with rheumatoid arthritis who engage in joint problem-solving and emotional support experience lower depression and anxiety. The research highlights the importance of dyadic coping in improving relationship quality and patient well-being.
Rice University researchers developed an electrochemical reactor to reduce energy consumption in direct air capture. The new design has achieved industrially relevant rates of carbon dioxide regeneration and offers flexibility, scalability, and lower capital costs.
Researchers developed an AI model that can identify and measure aggressive prostate cancer lesions with high accuracy. The model's estimates of tumor size were associated with the likelihood of cancer recurrence or metastasis.
The ECLIPSE trial found that routine orbital atherectomy had similar outcomes as conventional balloon angioplasty before stent implantation. Procedural complications were largely similar between groups, with no reduction in target vessel failure.
A novel ratiometric fluorescent probe was synthesized to detect native human albumin (HA) activity in patients with hepatitis B cirrhosis and hepatocellular carcinoma. Native HA activity levels were significantly higher in low albumin groups, correlating with increased severity of liver disease.
Astronomers can now analyze powerful space explosions more efficiently using a novel model developed by Syracuse University physicist Eric Coughlin. The model helps track the evolution of shockwaves generated during these events, enabling researchers to infer properties such as energy. Coughlin's research will aid in the detection and ...
Twelve healthcare innovators have been shortlisted for the Global Healthcare Innovation Competition, with seven candidates selected for the 'Young Innovators' category. The competition aims to nurture transformative health solutions, providing a platform for innovators to develop and scale their ideas.
Radiologists who had access to questionnaire information during MRI interpretation achieved a near statistically perfect agreement with spine specialists. This improved diagnostic accuracy and confidence, avoiding diagnostic discrepancies between radiologists and spine specialists.
Researchers from Peking University have identified a new compound, C7, that retains the therapeutic effect of obeticholic acid without causing itch. The study reveals the molecular mechanism of bile acids activating hX4 to induce cholestatic itch, offering hope for more effective and comfortable liver disease treatments.
A new study by University of Technology Sydney researchers challenges the Infinite Monkey Theorem, finding it unlikely a monkey can type out Shakespeare's works before the universe ends. With around a 5% chance, even an increased number of monkeys would not produce the Bard's entire works.
A new NASA-led study finds that the Earth's far northern permafrost region has become a net contributor to global warming due to methane emissions. The thawing permafrost is releasing stored carbon as greenhouse gases, shifting the region from being a sink to a source of warming.
A UTEP student has developed an innovative method to desalinate water, which converts over 90% of salt water to fresh water. The new technique, called salt-free electrodialysis metathesis, uses ion exchange membranes and electrical currents to separate salt from water.
Scientists at Max Planck Institute for Dynamics and Self-Organization created a navigation system for artificial microswimmers, enabling control over their movement using electric fields and flow. The system generates various motility patterns, including adhesion to channel walls or centerline motion.