Researchers discovered a previously unknown class of compounds in the fungus Bipolaris victoriae S27 that effectively kill colorectal cancer cells. The most effective compound, bipoterpride No. 2, targets the DCTPP1 enzyme and shows promise as a potential new treatment option.
A new zone-regulated interfacial polymerization strategy creates acid- and alkali-resistant nanofiltration membranes with high separation selectivity for lithium recovery. The strategy improves membrane performance and manufacturing stability by controlling monomer diffusion behavior.
Research finds ocean connectivity impacts herbivorous reef fish groups, critical to coral reef resilience, and sea surface temperature and chlorophyll levels predict fish distribution. Protecting reefs is essential for rapidly growing communities dependent on reefs, vulnerable to climate change.
Combining visible light with electrochemistry improves CO2 conversion rates and selectivity, enabling the production of valuable products such as carbon monoxide and hydrogen. The study's findings have significant implications for catalysis research and industrial applications.
Researchers at Pusan National University developed a fast-responding colorimetric sensor with an expanded color gamut, capable of detecting humidity and other environmental changes in real-time. The sensor outperforms previous designs with a wide color representation and rapid responsiveness.
Research reveals climate-driven wildfires in extratropical forests are now the leading source of global fire emissions. Extratropical regions have surpassed tropical areas in contributing to fire-related carbon emissions, highlighting the urgent need for addressing emissions and safeguarding forest carbon sinks.
A team of researchers has identified numerous bacteria with potential therapeutic applications, including those related to respiratory diseases. By analyzing the microbiome of humans and animals, they have discovered genetic blueprints for natural products that could be used to develop new medications.
A new study from Boston University School of Medicine found that cannabis use among young adults in Georgia did not increase following recreational use legalization. However, they discovered an age of first use increased significantly and cannabis use was associated with other risk behaviors.
Researchers at ETH Zurich have discovered a new predatory bacterium, Aureispira, that uses grappling hooks and cannons to capture prey. The bacterium's molecular structures resemble those of pirate tools, allowing it to entangle and kill its victims quickly.
A special issue of the Journal of the Academy of Nutrition and Dietetics reviews the history of the Women's Health Initiative, which has contributed significantly to the science of nutrition. The initiative's findings have led to a reduction in breast cancer cases and improved blood lipid management among postmenopausal women.
A new study by Duke University researchers reveals that smaller, specialized science publications have a disproportionate impact on conservation efforts. The team found that journals focused on specific regions or organisms were often cited more frequently by federal agencies than high-impact journals.
Researchers developed a wavelength sensor using photocurrent waveforms, achieving precise wavelength recognition with an error rate below 0.1%. The approach offers valuable insights for future spectrum optoelectronic devices.
A study by the University of Barcelona found that 35.4% of GBHSH community members use doxycycline as DoxyPEP, which may be associated with a decrease in chlamydia diagnoses but raises concerns about antibiotic resistance and misuse.
Research published by the American Psychological Association found that unpaid caregiving contributes billions of dollars' worth of labor annually, yet is often overlooked in societal value. The study suggests that people with lower socioeconomic status are more likely to provide care within their social networks but perceive themselve...
Scientists have identified a key driver of brain inflammation in neurological diseases, proposing a new treatment approach by neutralizing fibrin. This protein, involved in blood coagulation, triggers neurologic diseases by hijacking the immune system, resulting in damaged neurons.
A new study found that fibroblast growth factor 21 (FGF21) is an independent predictor of all-cause mortality in older adults. The Polsenior2 study revealed that middle and high FGF21 levels were associated with increased mortality risk, particularly when adjusted for age, co-morbidities, and blood parameters.
A new study finds that the gene for starch-digesting saliva may have first duplicated more than 800,000 years ago, seeding genetic variation that shapes modern diet. This early duplication set the stage for significant variation in the amylase region, allowing humans to adapt to shifting diets with increasing starch consumption.
This study investigates pressure effects on MOFs/COFs, revealing the relationship between structure and PL. High-pressure techniques enable modulation of structural and optical properties, paving the way for practical applications in fields like sensing and imaging.
Researchers developed a new method to capture complex mixtures of organic chemicals in blood, finding that many pregnant women carry a mixture of neurotoxic chemicals. The study revealed that these mixtures can act additively to produce harm, even at concentrations below individual chemical thresholds.
Researchers at VCU Massey Comprehensive Cancer Center are exploring a new approach to treating liver cancer using immunotherapy and a newly developed drug that inhibits the MYC gene. The four-year grant aims to identify effective treatment combinations for hepatocellular carcinoma, improving patient survival rates.
A new study from the A.J. Drexel Autism Institute has released findings that underscore critical challenges and opportunities in transitioning autistic youth into adulthood. The research emphasizes the need for improved services and supports, as well as the importance of prioritizing autistic perspectives and cultural considerations.
A new benchmark, V-score, has been developed to tackle quantum many-body problems. The V-score combines energy and fluctuation data into a single number, making it easier to rank different methods based on accuracy.
A Chinese research team has made a significant breakthrough in understanding the origin of life by discovering abiotic organic compounds in the oceanic crust. The researchers proposed a molecular mechanism for organic condensation, revealing a crucial role of goethite in catalyzing the synthesis of abiotic carbonaceous matter.
Experts from The Independent Panel for Pandemic Preparedness and Response urge leaders to take action against Mpox, a more dangerous virus now spreading across borders. The previous outbreak was neglected, highlighting the need for increased investment and cooperation to prevent further harm and global spread.
Researchers identified a protein that could improve the cardiovascular health of patients with progeria, a rare genetic disorder. The discovery provides promising insights into potential treatments targeting cardiovascular complications in HGPS.
Researchers have discovered a giant infrared bulk photovoltaic effect in tellurene, allowing for broad-spectrum neuromodulation. The study found that tellurene nanomaterials can elicit action potentials under broad-spectrum light irradiation, comparable to electrical stimulation.
The Center for Genomic Diagnostics at the University of Illinois will develop sensitive and rapid biosensors to detect African swine fever virus. The grant aims to improve on-farm detection and surveillance, providing timely control measures.
A new work plan will facilitate joint funding of research projects in areas like Cultures, Agri-food, Technology, and Health. The first joint call for proposals is scheduled for April 2025.
A new study reveals that online grocery retailers often don't provide essential nutrition information, such as calories and allergens, making it difficult for consumers to make informed choices. The lack of accessible food labeling poses a significant risk to public health, with marketing claims dominating the online shopping experience.
A comprehensive study reveals significant impacts of chlorine emissions from open biomass burning on air quality in Asia. The research provides valuable insights into the influence of these emissions on atmospheric chemistry and offers crucial information to mitigate regional air pollution.
Researchers have created a new diagnostic tool using machine learning to detect schistosomiasis, a persistent parasitic infection affecting an estimated 250 million people. The tool can identify low levels of the infection and distinguish between active and past infections, leading to earlier treatment and improved long-term outcomes.
Researchers developed a new crystal rod design that improves heat dissipation and reduces thermal lensing effects, resulting in higher laser output power and efficiency. The concave YAP/Tm:YAP/YAP bonding rod produced the highest quality laser beam, enabling high-performance near-infrared lasers.
Researchers at Rensselaer Polytechnic Institute developed a polymer film infused with a special chalcogenide perovskite compound that produces electricity when squeezed or stressed. The material has shown promising results, including powering LED lights and potentially being used in machines, infrastructure, and biomedical applications.
A study led by UMass Amherst found no significant improvement in asthma care for Medicaid-insured children compared to those with private insurance. Despite the launch of primary care-oriented Medicaid ACOs in Massachusetts, disparities in quality of care persist, with worsening emergency department/hospital use for children with Medic...
Researchers at Worcester Polytechnic Institute have discovered a new method to create high-performance alkaline batteries using iron and silicate. The process suppresses hydrogen gas generation, improving the energy efficiency of battery systems.
The study found that individuals receiving methadone had a lower risk of treatment discontinuation compared to those receiving buprenorphine/naloxone. Additionally, the risk of mortality while receiving treatment was similar between medications, with no significant differences observed.
Researchers have introduced Tune-IMS, a technique that improves the precision of isochronous mass spectrometry for measuring short-lived atomic nuclei. The method has been successfully tested on several nuclides and has shown higher precision than previous IMS methods.
A team of researchers from UConn and Washington State University explored how environmental DNA (eDNA) can help better understand population size and health in wood frogs. They found that environmental factors impact eDNA concentrations, but the precision of this method remains unclear due to sample-to-sample variation.
A WVU researcher says ancient tree rings can record rare and extreme space weather events, including geomagnetic storms. The study aims to better understand how to prepare for such events and mitigate their impact on communication satellites and astronauts.
Forest fires globally emitted half a billion tonnes more CO2 in the last two decades, with increased severity and extent driven by climate change. The study reveals alarming shifts in forest fire patterns, posing significant challenges for global targets to combat climate change.
Researchers found that Democrats and Republicans generally agree on what to censor when it comes to hate speech, with both parties prioritizing similar targets and severity levels. The study's findings suggest that social media companies can find consensus policies that get broad support, even in a highly polarized era.
Researchers discovered GAME15, a crucial protein for controlling steroidal glycoalkaloids and saponin production in Solanum plants. The study also showed that steroidal saponins play an ecological role in insect defense, with GAME15 knockout plants being more susceptible to herbivores.
Researchers at WashU Medicine used a novel approach to examine the genetic building blocks of risk for mental health problems in teens. The study found associations between genetic predisposition and modifiable risk factors, such as screen time, stressful life events, and environmental conditions like neighborhood crime rates.
A new study on the James Bond franchise reveals that regressive nostalgia can pose a significant threat to brands by attracting exclusionary consumers. These consumers cling to idealized past versions of brands and resist attempts to modernize them, posing challenges for marketers.
A new study shows that an AI tool can help people with different views find common ground by producing statements that convey the majority opinion while incorporating minority perspectives. Participants preferred and rated these outputs as more informative, clear, and unbiased compared to those written by human mediators.
A new study questions current approaches to predicting vessel strikes on whales, revealing notable inconsistencies across different models. The researchers highlight the need for accurate modeling to mitigate against modern-day risks threatening whale survival.
A study at Boston Children's Hospital highlights the complexity of infection prevention and control measures in pediatric healthcare. The conventional method of calculating IP staffing needs does not accurately reflect the current demands of healthcare systems or pediatric patients, leading to a shortage of resources.
The Smithsonian Tropical Research Institute will use the grant to apply a free, definitive standard for quantification of forest carbon everywhere. The project aims to provide accurate estimates of carbon storage and change in forests globally, enabling countries, companies, and landowners to offset their emissions.
A new study published in Science reveals that the salivary amylase gene (AMY1) may have first duplicated more than 800,000 years ago, seeding genetic variation that shapes human digestion of starchy foods. This early duplication allowed for increased starch-digesting efficiency and may have played a role in human adaptation to new diets.
Scientists have identified over 23,000 genes known as auxiliary metabolic genes (AMGs) that viruses 'steal' from ocean microbes, affecting 37% of metabolic pathways. The research catalogues these genes, shedding light on the vital role of viruses in nutrient cycling and oxygen production.
Researchers uncover role of SUMOylation in reactivating dormant neural stem cells, allowing brain development and repair. Absence of these proteins hampers neuronal growth and leads to microcephaly-like phenotype.
A new study found that people with opioid or alcohol use disorder who take Ozempic or similar medications have a lower rate of opioid overdose and alcohol intoxication. The medication, which treats diabetes and weight-related conditions, may also alter the brain's reward-response pathways associated with substance use.
A new study discovered toxic 'Forever Chemicals' in tap and bottled water from around the world, with 99% of samples containing PFOA and PFOS. Treatment methods such as boiling and activated carbon filtration can substantially reduce PFAS concentrations, with removal rates ranging from 50-90%.
A UC Riverside study found that men concerned about masculinity are less likely to forgive coworkers for minor transgressions, instead opting for revenge or avoidance. However, a simple intervention where participants describe experiences making them feel 'real men' can increase forgiveness.
During recent hurricanes Harvey, Imelda, Laura, and Florence, social media buzz focused on politics, pets, and human-interest stories, drowning out important public safety messages. Researchers found that descriptive messaging about storms outperforms safety messages in reaching a broad audience.
A team of researchers has identified a genetic variant associated with severe ulcerative colitis, which may help predict patient outcomes and guide targeted treatment approaches. The study found that patients carrying the HLA-DRB1*01:03 variant were more likely to require major surgery within three years of diagnosis.
Researchers develop laser solid-phase synthesis technique to produce graphene-shell encapsulated CrMnFeCoNi nanoparticles, exhibiting excellent electrocatalytic activity towards oxygen evolution reaction. The method offers simplicity, generality, and tunability to synthesize phase-separation-free HEA nanoparticles.
Researchers at the University of Chicago have developed a new way to measure the behavior of single electron defects in diamond, which can destroy quantum state memory. By studying the defects' spin and charge dynamics, scientists hope to create even better quantum sensors with long coherence times.
Scientists from the Institute of Nuclear Physics have discovered that near-earth microquasars are a significant source of gamma photons with extremely high energies. This finding challenges the previous understanding of ultra-high energy cosmic radiation and opens up new avenues for research in the field.
Researchers found that ultra-processed foods, including diet options, bring distinct risks for people with type 2 diabetes. Consuming more ultra-processed foods is closely linked with higher blood sugar levels, while a diet rich in minimally processed or unprocessed foods improves control.