A systematic review of 40 studies found associations between outdoor air pollution and differences in children's brain volumes, connections, and markers for Alzheimer's disease. The study suggests that even low-level pollution can impact brain development, highlighting the need for policy changes to reduce exposure.
The 'MiCCrobioTAckle' project investigates the complex interactions between the gut microbiome and tumor cachexia to find ways of slowing down muscle breakdown. Twelve doctoral researchers from twelve countries will work together across Europe, gaining new insights into the relationship between the gut microbiome and cancer cachexia.
Researchers estimate that 7% of hospital patients receiving general medical care experience harmful diagnostic errors, most of which are preventable. The study suggests new approaches to surveillance and integrating AI tools into the workflow can minimize their prevalence.
Researchers at the University of Nottingham uncover key regulators of malaria parasites' cell division, revealing NEK1 as a potential drug target. The study aims to find new therapeutic targets for controlling malaria transmission.
Researchers developed an AI-driven approach to model complex hand movements, overcoming current limitations in neuroscience and biomedical engineering. The model achieved a 100% success rate in controlling virtual Baoding balls, showcasing its strength in various challenging situations.
A new technology developed by Dr. Jaeyeon Pyo's team uses light to visualize nanoscale glass microcapillary tips, allowing precise and delicate contact with other objects. The method, which surpasses the resolution limits of optical microscopes, is a remarkable achievement in biotechnology and manufacturing.
The new report finds breast cancer mortality rates overall have dropped by 44% since 1989, averting approximately 517,900 breast cancer deaths. However, the incidence of breast cancer has continued to rise, with a 1% annual increase from 2012-2021.
The study reveals high levels of potentially pathogenic bacteria in microplastics and fish consumed by the local population, threatening the entire natural ecosystem and human health. The Cénaga Grande de Santa Marta, a shallow lake ecosystem, is also home to numerous bacterial species that can cause infections, including Vibrio cholerae.
Researchers have developed a new model of the electric double layer, accounting for various ion-electrode interactions. The model predicts a device's ability to store electric charge and aligns with experimental results.
A study by University of Edinburgh researchers suggests that high installation costs for heat pumps are slowing widespread adoption in the UK. Despite projections of cost reductions, the actual savings are unlikely to meet government targets.
A recent study by Washington State University researchers found that women are more inclined to purchase wine with labels featuring feminine gender cues. The study's lead author noted that winemakers may want to pay attention to the perceptions of this understudied group, which represents 59% of U.S. wine consumers.
A new INSEAD study finds that the #MeToo movement led to a significant decrease in demand for high-heeled shoes and stockouts of stereotypically feminine products. The researchers surveyed over 1,000 women in the US and found a rebellion against traditional gender stereotypes drove this shift.
Researchers identify a plausible geological environment where nucleic acids can replicate and potentially lead to life. The study reveals a circular fluid flow at the gas-water interface drives strand separation, allowing replication to occur.
The American College of Chest Physicians has released a new clinical guideline on endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) specimen processing and handling to standardize the process. The guidelines aim to improve diagnostic yield and specimen preservation for downstream ancillary testing.
Researchers at McMaster University have identified a critical vulnerability in metastatic brain cancer that can be exploited with new drugs. By targeting an enzyme called IMPDH, they anticipate preventing brain metastasis from occurring. The study has shown promising results and could lead to an alternative treatment option for patients
Researchers studied the 4.8-magnitude Tewksbury earthquake, which surprised millions with its strong shaking reports despite minimal damage near the epicenter. The study found that the rupture direction may have funneled the shaking away from the epicenter and toward the northeast.
A new study reveals that Brazil's democracy has been weakened by authoritarian populism, which has undermined welfare systems and human rights protections. This has created an exclusionary view of citizenship and intensified social conflicts, posing a threat to the country's democratic future.
The American Academy of Pediatrics recommends a multidisciplinary approach to create supportive learning environments, reducing harm from suspension and expulsion. Research shows that exclusions don't deter misbehavior and instead create significant mental and physical health harms.
Shailaja Paik, a University of Cincinnati professor, has been awarded a MacArthur fellowship for her groundbreaking research on Dalits and caste inequality in India. The grant will support her work on promoting education and human rights for marginalized communities.
Research suggests that immigrant assimilation patterns have remained consistent over the past century, with immigrants still working low-paying jobs and their children entering the middle class. Attitudes toward immigration are more positive than ever before, but also more polarized by political party.
Researchers at the University of Pennsylvania School of Engineering and Applied Science have discovered a novel means of directing lipid nanoparticles to target specific tissues. By incorporating siloxane composites into ionizable lipids, they were able to achieve tissue-specific delivery, particularly to the liver, lungs, and spleen.
According to a study from Linköping University, 29% of current and former Swedish cheerleading athletes reported experiencing psychological abuse. The most common reason was feeling frozen out of the community or being manipulated, while lack of support from coaches and injuries were also major contributors to athletes quitting the spo...
The expert panel discussion sheds light on the best practices for injecting hyaluronic acid (HA) fillers in the infraorbital hollows. Top surgeons share their preferred fillers and techniques, providing valuable insights for treating undereye dark circles.
The new framework, called SLIViT, has been developed by UCLA researchers and achieved accurate disease risk biomarkers detection from medical scans. It consistently achieves better performance compared to domain-specific state-of-the-art models.
Researchers successfully activated a specific memory circuit in mice using brain-imaging technology. The study found that stimulating neurons in two areas of the mouse brains reactivated spatial memory and caused the mice to seek shelter.
Researchers developed a modular click chemistry method to synthesize catechol derivatives, which showed potent inhibitory effects against SARS-CoV-2 3CL pro with low cytotoxicity. The study demonstrates the feasibility of this approach for natural-product-based structural modifications in antiviral drug discovery.
Researchers at MIT developed a security protocol that leverages quantum mechanics to guarantee secure data transmission during deep-learning computations. The protocol encodes data into laser light, making it impossible for attackers to copy or intercept information without detection.
A new American Thoracic Society report provides practical frameworks to address systemic racism in asthma care. The report highlights the need to engage affected communities and critically evaluate funding mechanisms to promote antiracism practices in research.
Researchers explore immune activation and tumor-promoting transcription factor FOXM1's role in CDK4/6-MEK resistance. They suggest targeting the oncogenic network of CDK4/6, MEK, PD-L1, and FOXM1 as future treatment options for MPNST patients.
A six-month study in the UK found that ParkRun participants experienced improved life satisfaction, particularly for those who were previously inactive. The study estimates a cost-effectiveness range of £16.70 to £98.50 for every pound spent on running.
A new study found that nearly six in ten Americans have pro-inflammatory diets, increasing the risk of health problems like heart disease and cancer. Anti-inflammatory foods such as garlic, ginger, and turmeric can help combat chronic conditions like diabetes and depression.
A new study presents an innovative curriculum for nursing students, exposing them to geriatric care early in their training with the goal of increasing interest in specializing in care for older adults. The curriculum uses virtual standardized patients, providing a higher level of training and covering knowledge, attitudes, and skills.
Researchers have developed a lab-grown spine model that can test the effects of valproic acid on fetal development. The study found that co-treatment with Rapamycin can prevent the negative effects of valproic acid, enabling women to take life-saving medication while having healthy children.
A new study reveals high levels of airborne plasticizers in Southern California, including phthalates known to cause reproductive harm and cancer. The study uses silicone wristbands to track exposure to these chemicals, finding that daily levels are both high and persistent.
Scripps Research scientists develop a new approach to designing drugs that selectively bind to cancer-related proteins and their paralog counterparts. By identifying a druggable site on the paralog, they characterize drugs that only bind to the protein of interest, potentially leading to more effective treatments for certain cancers.
Researchers developed a novel approach to optimizing siRNA-loaded lipid nanoparticles using NMR-based molecular-level characterization. Pre-mixed LNPs exhibit superior gene-silencing effects due to a stacked bilayer structure that enhances gene silencing.
A study by University of Potsdam researchers analyzed the data of 1585 wild animals fitted with GPS collars, finding that 30 species changed their behavior significantly after release. The animals generally recovered within four to seven days, with larger ones and those in human-influenced habitats returning more quickly.
The 11th Heidelberg Laureate Forum brought together top researchers to discuss climate change, AI differences between humans and machines. The event featured workshops, panels, and networking opportunities for future collaborations.
SEARCH aims to accelerate healthcare innovation by generating FAIRified synthetic data for use in AI/ML models, enabling large-scale data collaborations while preserving privacy and compliance. The hub will deliver reliable methodologies for synthetic data generation, significantly increasing the availability of interoperable datasets.
A new study estimates that cool roofs could have saved up to 249 lives in London during the 2018 record-setting hot summer. If widely adopted, cool roofs would reduce the city's ambient temperature by about 0.8 degrees C on average.
A new synthesis of regional climate data highlights the need for climate adaptation policy based on the latest regional climate science. Emerging signals of climate change are expected to significantly alter monsoon intensity, leading to substantial societal impacts in tropical and subtropical regions.
A new study has identified the genetic elements responsible for transforming classical Klebsiella pneumoniae into a devastating, drug-resistant killer. Researchers found that the plasmid pVir is the primary determinant of hypervirulence in this bacterium.
A new study by economists at the University of Zurich finds that engaging in public discourse increases socially responsible market behavior regardless of participants' social norms and values. The researchers conducted three lab experiments with over 2,500 participants and observed a significant increase in trade with fair products wh...
Brendan G. Carr, MD, MS, receives the Colin C. Rorrie Award for Excellence in Health Policy, recognized for his work on building regional systems for emergency care and advocating for increased collaboration between public and private sectors. Ugo Ezenkwele, MD, MPH, receives the Leon L. Haley Jr. Award for Excellence in Diversity, Inc...
A team of researchers found that the use of microbial biofertilisers and algae-based biostimulants can significantly enhance both the yield and quality of organic tomatoes. The treatments improved processes like nutrient absorption and stress tolerance, supporting overall crop performance.
The study analyzed the genetic profiles of 80,000 people and found that repeat expansion disorders (REDs) are common across different populations. The findings suggest a significant shift in how we think about genetic testing, profiling, and counseling for these conditions.
Researchers seek to identify Hispanic women at risk of developing chronic diseases through early screenings or interventions, aiming to improve health outcomes for millions in the population.
A new study finds that fatal falls among older people in the US have a higher cost than firearm deaths, with an estimated average medical cost of $1,427,773,589 for fatal falls compared to $246,456,666 for firearm injuries. The researchers highlight the urgent need for preventive measures to address this growing public health challenge.
The study reveals substantial gaps in compensating for lost protected areas, risking global efforts to conserve biodiversity. Protected areas play a crucial role in conserving species and ecosystems, but PADDD events expose them to extinction risks.
Scientists developed a streamlined approach to assemble 2D molecular structures using a supramolecular scaffold, enhancing the efficiency of singlet fission and paving the way for advancements in solar cells. The new method created two distinct 2D self-assembling structures with high quantum yields, outperforming previous designs.
Scientists highlight critical knowledge gaps in Arctic coastal ecosystems due to climate change, which are having broader implications for both ecological and human systems. The consequences of these changes extend beyond the open Arctic Ocean, requiring adaptive measures to ensure socioecological sustainability.
Researchers at La Jolla Institute for Immunology have developed six lines of humanized mice to study human cases of COVID-19, shedding light on SARS-CoV-2's movement through the body and varying symptoms. The models help understand how different genetic backgrounds influence disease progression.
A study links droughts in Southern Africa to a massive plankton bloom off Madagascar's southeast coast. Climate warming intensified the dust particles carried by wind, which acted as fertilizer in seawater, creating ideal conditions for phytoplankton growth.
Researchers have identified six epigenetic hallmarks that characterize transformed cells, including DNA methylation, viral reactivation, and histone protein modifications. These properties enable cancer cells to evolve and resist therapy, making them a key target for improving diagnosis and treatment.