Researchers at King's College London have developed a new brain organoid system that reduces variability and allows for longer-term recordings of neural activity. The approach enables the simultaneous study of multiple parallel cultures, providing a better understanding of how drugs or gene variants affect neural networks.
SourceKing's College London·JournalCell Reports Methods·DateMar 27, 2026
A protocol for detecting targeted chromosomal deletions induced by zinc finger nucleases allows researchers to estimate the frequency of ZFN-induced genomic deletions using PCR-based methods. Immunoprecipitation is also optimized with detailed instructions for lysis conditions, protease inhibitor cocktails, and general preparation.
SourceCold Spring Harbor Laboratory·JournalCold Spring Harbor Protocols·DateAug 2, 2010