Articles tagged with Luciferase Assays
This study identified PIBP4, a PRA protein, as a crucial component of the PigmR-mediated immune signaling pathway in rice. The absence of PIBP4 and its interacting partner OsRab5a compromised blast resistance by disrupting PigmR's microdomain localization.
The researchers have developed a groundbreaking method to expand the color palette of bioluminescent protein to 20 distinct colors, enabling advanced simultaneous multi-color imaging. This innovation makes it significantly easier and more cost-effective to monitor multiple targets or track individual cells within a population.
A new assay developed by researchers at Baylor College of Medicine can study six different cellular pathways simultaneously, providing a deeper understanding of cancer and other complex diseases. The multiplexed hextuple luciferase assaying saves time and expense compared to traditional approaches.
Researchers at Keck School of Medicine of USC develop a new laboratory tool, the Topanga assay, to improve cancer therapy effectiveness. The assay uses bioluminescent marine organisms' enzymes to measure chimeric antigen receptors on cancer-fighting white blood cells.
Scientists at the Keck School of Medicine of USC developed a test using marine animal luciferases to measure cell death in response to cancer immunotherapies. The Matador assay detected cell death in as little as 30 minutes, exceeding existing assays and offering a fast, inexpensive alternative.
Researchers discovered that an RNA aptamer specific to ricin's catalytic chain can protect cells from ricin-induced damage. The aptamer, called 31RA, inhibits the toxin's enzymatic activity and neutralizes its translation-inhibiting effects.