Articles tagged with Electron Microscopy
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers at Vanderbilt University found that aging cells remodel their endoplasmic reticulum through ER-phagy, a process linked to lifespan and healthy aging. This discovery highlights the ER as a potential drug target for age-related chronic conditions.
A team at Graz University of Technology found that espresso is a favourable and environmentally friendly substitute for uranyl acetate, which is highly toxic and radioactive. The results showed equally good quality images under the microscope with coffee staining.
The University of Tennessee at Knoxville has received a $251,650 DOE award to establish an in-situ scanning electron microscopy platform for irradiated materials. The high-resolution microscope will enhance the university's research capabilities in extreme environments.
Scientists at Max Born Institute develop technique to generate µJ-level tunable few-fs UV pulses in VUV range. They successfully characterized few-fs pulses tuned between 160 and 190 nm using electron FROG, revealing pulse duration of 2-3 fs.
Materials scientists at the University of Minnesota have discovered a way to control tiny 'flaws' inside ultra-thin materials, giving them new properties. The study found that patterned regions can achieve up to 1,000 times higher density of extended defects than unpatterned areas.
Actin filaments play a crucial role in cell movement and stability. A trio of proteins - coronin, cofilin, and AIP1 - regulate their disassembly to prevent unproductive elongation and ensure optimal power transmission. The researchers used cryo-electron microscopy to visualize the molecular choreography, revealing coordinated steps and...
Researchers developed a new model and theory to explain nanoparticle growth dynamics, accounting for six essential characteristics of nanoparticle growth. The new theory provides fresh physical insights into the role of nanoparticle motion and configurational degeneracy on their nucleation and growth.
Researchers from Helmholtz-Zentrum Dresden-Rossendorf discovered how diatoms chemically interact with uranium, finding it bound both on the surface and within the algae. The team's findings provide initial insights into the chemical bonds formed and help understand the impact of uranium release on natural cycles.
Lehigh University Professor Christopher J. Kiely has been awarded the 2025 Presidential Science Award from the Microanalysis Society for his outstanding contributions to microanalysis research. He is recognized internationally for his decades-long leadership in microscopy education through the Lehigh Microscopy School.
Researchers achieved direct measurement of nanometer-scale charge distributions formed at ferroelectric domain interfaces using electron microscopy. This study contributes to a deeper understanding of ferroelectric devices and their performance improvement.
Researchers have developed a technique to observe phonon dynamics in nanoparticle self-assemblies, enabling the creation of reconfigurable metamaterials with desired mechanical properties. This advance has wide-ranging applications in fields such as robotics, mechanical engineering, and information technology.
A study by the CSIC-UMH Institute of Neurosciences uncovers how flies' flight stabilizers, the halteres, take shape. The structure is stabilized by a sophisticated cellular system that connects its two surfaces through an internal framework.
Researchers at Rice University have developed a new method to fabricate ultrapure diamond films for quantum and electronic applications. By growing an extra layer of diamond on top of the substrate after ion implantation, they can bypass high-temperature annealing and generate higher-purity films.
University of Missouri scientists have developed an ice lithography technique that etches small patterns onto fragile biological surfaces without damaging them. The method uses frozen ethanol to protect the surface and apply precise patterns.
A global team of neuroscientists has created the most detailed wiring diagram of a mammalian brain, revealing new cell types, characteristics, and organizational principles. The MICrONS Project's findings have transformative potential for neuroscience and medicine, offering a blueprint for understanding intelligence and disorders like ...
Scientists at NIST discovered a novel aluminum alloy with enhanced strength through quasicrystals, revolutionizing 3D printing. The unique crystal structure breaks the regular pattern of perfect crystals, causing defects that make the metal stronger.
Materials Research Society elects Miaofang Chi and Rigoberto “Gobet” Advincula as Class of 2025 Fellows for their outstanding work on novel electron microscopy methods, advanced polymers, and nanostructured materials. New Fellows will be recognized at the MRS spring meeting in April 2025.
An international research team developed a user-friendly software method called Segment Anything for Microscopy, which can precisely segment images of tissues, cells, and similar structures. The new model improved performance for cell segmentation, enabling researchers to automate tasks that previously took weeks of manual effort.
Researchers found that ornamental never never plants can store water for up to 45 days, maintaining photosynthetic activity and chloroplast structure unchanged. This helps them adapt to drought conditions, a challenge for many crops.
Researchers used super high-resolution 3D electron microscopy images to study primary cilia in mouse brain tissue, revealing new information about their organization and function. The findings provide insights into how cilia behave in their natural environment and could help scientists understand their role in disease.
The Department of Energy's new research centers, led by SLAC National Accelerator Laboratory, aim to make microelectronics more energy efficient and operate in extreme environments. Researchers will focus on innovating material design, devices, and systems architectures to push computing and sensing capabilities.
Researchers used time-delayed laser pulses to capture electric and magnetic field vectors of surface plasmon polaritons, revealing a meron pair's spin texture. The study demonstrates stable spin structures despite fast field rotations.
Scientists have captured 3D snapshots of individual RNA nanoparticles in motion, showcasing the dynamic and intricate folding process. This breakthrough uses advanced electron microscopy to study RNA's flexibility, enabling new insights into its structure and potential applications in molecular medicine.
Researchers at Radboud University Medical Center developed a super microscope that combines live imaging and electron microscopy, allowing visualization of protein complexes in real-time. This technique opens up new avenues for studying arterial calcification and its potential link to COVID-19 vaccine entry.
Scientists have developed a new method for converting crystal to glass using electric current, reducing the need for high-power melt-quench processes. The discovery could transform data storage in devices and unlock wider applications for phase-change memory technology.
Scientists at The University of Tokyo successfully observe the existence of space charge layers in solid electrolyte fuel cells, shedding light on their impact on ion conduction. By controlling grain boundary structure, they can eliminate these layers and improve material performance.
Researchers developed an AI-based method to analyze kidney lesions in female patients with Alport syndrome, predicting renal prognosis and guiding treatment interventions. The approach uses a modified stain and deep learning to detect basement membrane lesions, showing a positive correlation with proteinuria concentration.
Researchers at SFSU have created three-dimensional molecular and anatomical maps of the inner neuronal circuitry of octopus arms. These 3D reconstructions revealed that cells at the tip of an arm are different from those at the base, allowing for new questions to be posed about how cells communicate with one another.
Researchers at UC Irvine have made the first-ever atomic-scale observations of grain rotation in polycrystalline materials. They discovered that grain rotation occurs through disconnection propagation along grain boundaries.
Researchers have discovered living microbes in a 2-billion-year-old rock sample from the Bushveld Igneous Complex in South Africa. The team used advanced imaging techniques to confirm the presence of indigenous microorganisms, shedding light on the early evolution of life on Earth and the potential for similar organisms to exist on Mars.
Scientists at Sanford Burnham Prebys have developed a clearer picture of how crucial machinery in the human cell's recycling process for obsolete and misshapen proteins—known as proteasomes—are formed. The research team shed new light on how two protein chaperones bind on the top of the alpha subunit ring as it is constructed.
A University of Virginia engineer developed a workflow to combine advanced imaging technologies for improved understanding of porous bone, which could inform disease detection. The method allows for three-dimensional rendering of bone structure across various length scales.
Scientists at the University of Utah's Department of Chemistry developed a new contrast agent that allows for the simultaneous observation of cell structure and function in electron microscopy. The discovery could improve imaging tools used to study signaling in functioning cells and other molecular-scale processes.
Researchers at TU Graz have observed where lithium ions are stored and released from battery material during charging and discharging cycles. They found that even fully charged batteries retain lithium ions in the crystal lattice of the cathode, leading to a capacity loss. This knowledge can help increase battery capacity further.
Guan's lab will apply accumulated experience and methods to study SLC6A14, a sodium-coupled epithelial amino acid co-transporter involved in cancer and several chronic diseases. CryoEM will be used to determine the structure of SLC6A14, providing insight into its substrate specificity and inhibitory mechanisms.
Researchers have used cryo-electron microscopy to reveal the structural basis of how cells regulate ferritin, a protein that stores iron. This understanding could lead to the development of drugs that block ferritin's interaction with NCOA4, slowing down aggressive cancer cells.
Researchers developed a new technique to study charge density waves in materials, revealing two previously unobserved ways electricity can manipulate their state. The method allows for the observation of nanoscale lengths and nanosecond speeds, with potential applications in energy-efficient microelectronics.
A new study reveals that Cutibacterium acnes can persist in biofilms on implants for weeks, invading deep bone networks and causing chronic infections. The bacteria's ability to invade osteocyte lacuno-canalicular networks provides a novel mechanism for treating difficult-to-treat bone infections.
Researchers at University of Konstanz shape electron matter wave into left- or right-handed coils of mass and charge. This achievement has implications for fundamental physics and potential applications in quantum optics, particle physics, and electron microscopy.
The Marine Biological Laboratory has introduced two new microscopes for biological and biomedical research, providing a valuable resource for scientists and students. The instruments enable correlative imaging, allowing researchers to confirm results in different ways, and are expected to influence further development of advanced imagi...
Researchers developed a technique to study electrochemical processes at the atomic level, revealing unexpected transformations in a popular copper catalyst. The technique, called polymer liquid cell (PLC), enables scientists to observe composition changes during reactions in real time.
Researchers developed a new technique to view living mammalian cells using ultrafast pulses of illumination from a soft X-ray free electron laser. The microscope captured images of carbon-based structures in living cells with high spatial resolution and a wide field of view, revealing new insights into cellular biology.
A team of Harvard researchers, led by Jeff Lichtman, has created the largest synaptic-resolution, 3D reconstruction of a piece of human brain to date. The dataset contains 1,400 terabytes of data on neural connections in a tiny piece of human temporal cortex.
RMIT researchers have found that the liquid-solid boundary can fluctuate back and forth, with metallic atoms near the surface breaking free from their crystal lattice. The phenomenon occurs at unexpectedly low temperatures and is observed up to 100 atoms in depth.
Researchers discovered an alloy with exceptional strength and toughness across a wide temperature range, outperforming even cryogenic steels. The alloy's unique properties are attributed to the formation of rare kink bands that enable it to resist bending and fracture.
A team at the University of Tokyo has constructed an improved mid-infrared microscope that enables them to see the structures inside living bacteria at the nanometer scale with a resolution of 120 nanometers. This breakthrough can aid multiple fields of research, including into infectious diseases.
Researchers analyzed three distinct formins from fungi, mice, and humans, revealing a new paradigm in actin filament assembly. The structures show that formins encircle actin like an asymmetric ring, with one half stably bound and the other half loosely associated.
Researchers at the University of Nottingham have created a world-first device that can image individual cells' stiffness, potentially catching cancer earlier. The technology uses Brillouin scattering to detect stiffness down to billionths of a meter and could replace traditional biopsies with non-invasive, single-cell imaging.
Researchers at TU Graz developed a new method to analyze nanoporous materials using single electron microscope images. The technique determines the three-dimensional distribution of ions in crystal channels or nanopores, leading to a better understanding of aquamarine's blue color and potential applications in material science.
Researchers discover how S1P molecules are released from SPNS2 protein via small cavities, enabling potential treatment for inflammatory diseases. The study provides a foundation for designing future drugs targeting the protein.
The UK Centre for Multimodal Correlative Microscopy and Spectroscopy (CoreMiS) will enable researchers to analyze environmental samples with unprecedented detail. CoreMiS has already been used to study ancient artifacts, detect pollutants in drinking water, and investigate antimicrobial resistance.
Researchers have discovered nitrogen-bearing biorelevant molecules, including amino acids and nucleobases, in the Winchcombe meteorite. These findings suggest that the meteorite may have delivered crucial organic molecules to early Earth, potentially influencing the origin of life.
Research reveals that a small subset of bacterial cells produces deadly toxins while sacrificing themselves for the benefit of their comrades. The bacteria use a temperature-sensitive genetic switch to synchronize toxin production with cell enlargement, ensuring an efficient strategy for infection.
Researchers at TU Graz have made a breakthrough in manufacturing complex, free-standing 3D nanoarchitectures with precise shapes and sizes. They achieved this by precisely simulating the required optical properties in advance and completely removing chemical impurities, enabling new optical effects and application concepts.
Researchers at ISTA investigated the crucial set of synapses between neurons within the cerebellum, uncovering details of their function and development. The study used advanced techniques to look at the inhibitory synapses in great detail, revealing how they delicately influence the cell's signal output.
Focused ion beam technology has numerous applications in material processing, microelectronics, and life sciences. The instrument uses a finely focused ion beam for nanoscale analysis, prototype creation, and material modification.
Scientists have made significant progress in understanding ultrafast electron dynamics by tracking the motion of electrons released from zinc oxide crystals using laser pulses. The research team combined photoemission electron microscopy and attosecond physics technology to achieve temporal accuracy, enabling them to study the interact...
Researchers have developed a new technique to understand the relationship between atomic structure and electric polarization in 2D van der Waals ferroelectric materials. This discovery is expected to revolutionize domain engineering in these materials, positioning them as fundamental building blocks for advanced devices.
The Marine Biological Laboratory (MBL) has been awarded $4.3 million by the Massachusetts Life Sciences Center to expand its imaging capabilities. The grant will support the procurement of two state-of-the-art microscopes that can perform advanced imaging techniques, including 2D and 3D reconstruction from electron and light microscopy.
Researchers have developed a new microscopy technique using STED technology to visualize individual fibers in amyloid plaques, providing higher resolution than conventional light microscopy. This breakthrough allows for better understanding of the structure and morphology of Aβ aggregates and their role in Alzheimer's disease progression.