Articles tagged with Open Access
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Researchers developed 'Library on a Slide' technique to compare bacterial genomes, allowing for efficient identification of genes associated with biological processes. The method involves printing genomic DNA at high density onto a glass slide and uses fluorescently labelled probes to detect target genes.
The report highlights inconsistent data-access policies among nations and agencies, emphasizing the need for international efforts to promote open access. The authors call for an international framework to achieve this goal, making data sharing a rule rather than an exception.
A new tumor classification system combines molecular biology and classic pathology to provide a comprehensive and consistent way of typing tumors. The system uses both the type of cells that form a tumor and its molecular characteristics to determine its behavior, offering improved accuracy and insight into treatment options.
A study found that 71% of Japanese outpatients would like to make treatment decisions in collaboration with their physician. Patients prefer to involve their families in decision-making, but only allow them to support the patient's decision, not provide a third opinion.
Research suggests that hunger increases sensitivity to sugar and salt, as the body tries to consume food. However, this effect does not apply to bitter tastes, which may be more related to detecting toxins.
A new study found that people with short variants of the APOB gene region have significantly lower total and low-density lipoprotein cholesterol levels in their blood. This association may contribute to a protective role of these variants in younger adults, while being detrimental to longevity in older individuals.
Researchers found that tropical boubous sing the 'victory duet' more often after an invasion attempt than before or during playback of recordings. This rare context-specific birdsong is used to assert dominance and deter other birds from intruding into their territory.
Researchers reconstructed the timeline of eukaryotic evolution, showing that increased oxygen led to more varied cell types. Organisms with up to 50 different cell types evolved following the emergence of mitochondria and plastids around 2,300 million years ago.
A population-based study found that infants would benefit most from in-hospital palliative care, while older children with long-term illnesses require community-based and at-home services. Effective end-of-life care for all children needs simultaneous delivery of different modes of care.
Gerbrand Izaks and Rudi Westendorp propose a model where diseases are caused by cumulative risk factors, making every age-related change a potential symptom of an illness. This framework encourages doctors to reassess older patients' body functions, comparing results to 'normal values' from healthy young adults.
A new study has identified a link between the size of apolipoprotein(a), a protein component of low-density lipoprotein, and an increased risk of heart disease in overweight individuals. The research suggests that analyzing apolipoprotein(a) size may provide a reliable way to discriminate between those at high risk and those without.
Researchers discover that retroviral Gag proteins bind tightly to endophilin-2, a protein involved in cell membrane budding. This interaction is crucial for the production and spread of viruses.
Researchers estimated that only one further case of vCJD in Ireland is likely, based on exposure to BSE-infected beef. The study used data from the UK to calculate the future risk to the Irish population.
Open-access initiatives aim to make scientific research freely available online, with proponents arguing that it promotes science and improves human health. Critics, however, suggest that authors' payment models may compromise the quality of published research.
Refugees may experience limb thrombosis, low oxygen levels, and transmission of respiratory infections such as tuberculosis during flights. Measures should be taken to prevent these medical risks and ensure safe repatriation.
Patients with achalasia often experience impeded digestion due to reduced muscle contraction and sphincter relaxation. Research finds that nerve cell loss may cause constipation in these patients, which persisted even after treatment for achalasia.
Researchers found that silent piano practice altered brain activity patterns after just 20 minutes, with enhanced changes after five weeks of training. The study suggests a 'map' is formed between auditory pitch targets and motor skills, similar to Broca's area involved in speech processing.
PLoS Biology features peer-reviewed research articles on diverse topics, making outstanding science freely available worldwide. The journal's open-access model aims to increase interdisciplinary collaboration, speed scientific discovery, and potentially save lives.
Scientists identified 25 genes expressed differently in soldier and worker termites, with workers having higher levels of cellulose-degrading genes. Soldiers had higher levels of muscle- and cytoskeleton-related genes, suggesting their large mouthparts may be linked to these genes.
The UK has signed a landmark deal to make scientific research freely available online. BioMed Central's membership agreement commences on July 1st, waiving article-processing charges for all UK higher education staff. This move aims to increase the proportion of open-access articles published worldwide.
Researchers found that nitrogenous bases could protect primordial RNA from UV radiation, leading to a selective advantage and increased stability. This mechanism may have driven the origin of life on Earth, turning high UV levels into a key factor in the process.
New predictions suggest vCJD epidemic will decline with a comparable worst-case scenario of 540 UK cases between now and 2080. The researchers estimated the incubation time of vCJD to be 12.6 years, similar to Kuru, and calculated that only 40 future cases are expected within the next five years.
A recent study published in Malaria Journal found that current funding for the Roll Back Malaria movement is less than 7% of what is needed to achieve its goals. The authors recommend increasing aid and implementing more transparent reporting by donors to ensure the project's success.
Scientists have found that bacterial endospores can survive in a simulated Martian environment, raising concerns about future space missions. The discovery highlights the potential for Earth-borne endospores to hitch a ride to Mars and compromise efforts to detect life on the planet.
Researchers investigated sleep regulation in mice lacking cryptochrome molecules, revealing a new model for understanding sleep mechanisms. The study found that these mice did not exhibit increased non-REM sleep duration after sleep deprivation.
A new website, ICUnet, has been developed to help doctors and nurses find nearby intensive care beds. This system could prevent critically ill patients dying during transfers by providing a comprehensive, up-to-date list of available beds.