Articles tagged with Scientific Journals
Scientists use zebrafish to investigate the role of RAS mutations in melanoma formation and progression. The research found that altering signaling pathways can reduce the effects of RAS mutations, providing a potential therapeutic approach.
A new mouse model has been created to understand human neuronal diseases that impair feeling and movement. The mouse model mimics symptoms of Charcot-Marie-Tooth and hereditary motor neuronopathy, two conditions with no effective treatments.
The study found that estimated glomerular filtration rate (eGFR) equations, particularly eGFR5 and eGFR3, are reliable preoperative renal function tests for patients undergoing hepatectomy. These equations were compared to creatinine clearance (Ccr), with significant differences in postoperative serum creatinine levels
The study developed a molecular marker for Pi-deficiency in rats and evaluated the efficacy of Chinese materia medicas and probiotics. It found that middle doses of these recipes showed pronounced recovery activities, while higher doses did not.
Reorganizational Healing (ROH) is a new concept for wellness, healing, and personal growth that focuses on self-assessment and harnessing the body's innate ability to reorganize. By understanding the relationship between lifestyle choices and disease symptoms, individuals can achieve healthier, more fulfilling lives.
A study of over 1 million radiology reports found that side discrepancy errors, incorrectly noting the side of a lesion, were clinically important and occurred more frequently in female patients. Radiologists should verify these errors, while physicians and patients must also collaborate to ensure accurate clinical management.
Research in Management Science reveals that recommender systems can create self-reinforcing cycles favoring popular items, reducing diversity and serving consumers and producers poorly. To mitigate this issue, designers must consider modifications to limit popularity effects and promote exploration in their recommender systems.
Researchers used computer simulation to investigate the effects of duodenal stump geometry on gastric resection outcomes. The study found that certain geometric configurations can improve food transport and emptying, but may compromise pressure distribution.
A study published in World Journal of Gastroenterology found that small colon polyps can be removed without interrupting anticoagulation therapy, resulting in an acceptable bleeding rate. The procedure was performed on 123 patients with lesions up to 1 cm in size.
A study published in Journal of Cardiac Failure found that obstructive sleep apnea and central sleep apnea are prevalent in heart failure patients, with 47% experiencing moderate to severe breathing disorders. The prevalence was not decreased by beta-blockers and spironolactone treatment.
Researchers found that 15-month-olds struggle to distinguish Jamaican-accented words, but 19-month-olds exhibit cross-dialect recognition. By 19 months, children demonstrate phonological constancy for both familiar and unfamiliar words in any English dialect.
Researchers predict Yucca Mountain crest erosion due to local geology, potentially affecting repository stability. The study used a numerical landscape evolution model to explore the rate of erosional decay.
A new editorial in the FASEB Journal examines the risks of dietary supplements, highlighting regulatory loopholes that enable toxic substances to enter the market. Gerald Weissmann argues that these supplements represent unregulated drugs with tangible personal and professional consequences.
A study published in the Journal of Cell Biology reveals that a mutated Alzheimer's-related protein called presenilin helps form and maintain nerve cell connections. The findings suggest that failing nerve transmission might be an early step in the disease's pathology.
Researchers from three institutions applied harpin to head lettuce prior to harvest to prevent microbial contamination. The study found that harpin improved color, reduced browning, and increased phenolic compounds, which are linked to plant chemical defenses against microbes.
Researchers discovered a preference for processing information on the left side of faces, which can aid in facial recognition. In contrast, experts who read Chinese characters exhibit reduced holistic processing and show a left-side bias, indicating general visual expertise.
Elsevier has launched a new journal called Epidemics, which will focus on infectious disease dynamics. The journal aims to bring together researchers from various disciplines and provide a platform for high-quality papers in this emerging field.
A new study has developed a software that utilizes the Nintendo Wii gaming system's infrared sensor and accelerometer to enable flexible ways for radiologists to interact with patient images. This method may alleviate limitations of traditional keyboard-mouse interfaces and reduce repetitive motion injuries.
A study at the University of Arizona found that remote CT colonography is feasible in rural health centers using teleradiology. Technicians performed CTC exams on 86 patients and sent data to a local server for interpretation by an off-site radiologist.
Scientists have created a mouse model of Wolf-Hirschorn Syndrome, a genetic disorder characterized by physical abnormalities and developmental delays. The model, which mimics the disease's effects on cardiac valves and facial structures, offers a valuable tool for researchers studying human development and disease.
A study by University of Illinois scientists reveals the FRG1 gene is crucial for angiogenesis, contributing to blood vessel growth and organization in the retina. The findings support the idea that FRG1 expression is a main cause of visual deficits associated with facioscapulohumeral muscular dystrophy.
Researchers developed a novel approach to isolate high-quality RNA from Kupffer cells, overcoming technical obstacles. The method uses laser capture microdissection with India ink labeling, resulting in enriched mRNA and significant gene expression changes.
Researchers found that alpha-fetoprotein is highly expressed in developing rat colons, particularly at embryonic day 18.5, and decreases significantly as the animal matures. The protein is localized to mesenchymal cells throughout different developmental stages of the colon.
A study by Michael D. Dodd and colleagues found that inhibition of return occurs during visual search tasks, but not during other visual behaviors. Volunteers were tracked while viewing scenes to identify eye movements, revealing a 'facilitation of return' effect where previously fixated locations are shifted faster than new ones.
Researchers found that imagining a posture can affect behavior, suggesting that our 'peripersonal space' can be extended to influence actions. This ability may have advantages in determining realism and avoiding collisions.
A new study published in The FASEB Journal reveals that poor nutrition during pregnancy can lead to permanent genetic changes in the offspring, causing health problems such as diabetes, growth retardation, and cardiovascular disease. The researchers found that rat fetuses receiving inadequate nutrition became genetically primed to be b...
The recent special edition of Virology journal explores the past, present, and future of small DNA tumor viruses, including polyomaviruses, adenoviruses, and papillomaviruses. These viruses have led to fundamental discoveries in basic biology, unraveling complex aspects of host cells.
A recent analysis found that downloads and citations are highly correlated with a 0.74 correlation coefficient, indicating that downloads can be used as an alternative metric to measure article impact. Downloads mirror citations but become available about two years earlier.
Researchers have discovered a group of nerve ending receptors and chemicals that can activate them, providing a blueprint for the development of new laxatives. This breakthrough has the potential to make bowel movements easier, especially for infants and the elderly.
A recent study found that flood conditions can decrease soil aggregation stability by up to 20%, impacting crop production. The research suggests that reducing conditions contribute to the degradation of soil structure.
Research by Joshua M. Ackerman and John A. Bargh found that imagining another person's self-control can lead to a depletion of one's own self-control, causing impulsive behaviors like overspending. In experiments, participants who imagined exerting self-control in someone else performed worse on cognitive tasks after the simulation.
New research using African frogs reveals that alcohol 'hijacks' a molecule needed to produce retinoic acid, which is crucial for embryonic development. This leads to cellular disorientation and malformations in babies.
The study found that organic and rotational grazing systems were more profitable than conventional monocropping, despite increased risk exposure. The results suggest that governmental policy should support crop rotations and organic farming practices.
A new study identifies a clinical prediction rule that can accurately predict patients most likely to benefit from measures to prevent recurrent C. difficile infection, which has become the leading known cause of hospital-acquired infectious diarrhea in developed countries.
A space experiment has shown that bone-destroying cells sense the absence of mechanical resistance and react by destroying bone. This discovery helps explain why bedridden patients and astronauts experience bone loss, providing a potential new drug target for stopping the process.
Research reveals that specific HCV genotype 4a mutations affect treatment outcomes, with a higher frequency of mutations associated with sustained viral response. The study identifies potential targets for developing new assays to predict treatment efficacy.
A new study published in the Journal of Personality reveals that personality at adolescence predicts reproductive success later in life. Adolescents with socially dominant personalities were more likely to have children as adults, suggesting that status striving may be important for reproductive success even in modern humans.
The Journal of General Physiology explores the mysteries of TRP channels, which are crucial for various senses. The latest Perspectives series provides a comprehensive overview of their biophysics, protein structure, and gating processes, shedding light on areas in need of further exploration.
A new study published in Archives of Gerontology and Geriatrics challenges the concept of consensus in anti-aging medical intervention, citing diverse therapeutic approaches and conflicting opinions. Dr. Imre Zs.-Nagy proposes an open-minded approach to reconcile differences and achieve a realistic goal of aging intervention.
Researchers at Uppsala University have identified the three genes that determine warfarin dosage: VKORC1, CYP2C9, and CYP4F2. This discovery will enable more precise treatment and reduce the risk of bleeding or blood clots.
Research finds that three- and four-year-old children favor majority opinions, even in follow-up experiments with only two individuals present. This suggests young children can recognize and trust consensus, and remember group membership.
The research, led by Johan Bollen, created a high-resolution graphic depiction of the virtual trails scientists leave behind when they retrieve information from online services. The map reveals unexpected relations between scientific domains and emerging relationships capturing the collective interest of the scientific community.
Researchers found that 'dialectical bootstrapping' technique can improve accuracy of estimates across various domains by averaging conflicting opinions and considering potential errors. The study suggests this method can be an effective strategy for boosting individual decision-making.
Researchers found that describing past actions in the imperfective aspect (e.g. I was solving word puzzles) improves memory recall and performance on similar tasks compared to the perfective aspect (e.g. I solved word puzzles). This technique may be useful in behavioral therapy for increasing healthy behaviors.
Research reveals that chemicals in cranberries, called proanthocyanidins, prevent E. coli bacteria from attaching to urinary tract cells. This prevents the development of UTIs, which burden the healthcare system with significant treatment costs.
Researchers at UT Southwestern used a computer-based tool to analyze millions of abstracts and found nearly 70,000 highly similar citations. Journal editors' reactions to the investigation revealed varying attitudes towards dealing with plagiarism, with some admitting to having borrowed previously published material.
A new study explores how and when politicians can use fear to manipulate the public into supporting policies they might otherwise oppose. Politicians' use of fear is more likely with abstract topics that are difficult for citizens to observe.
A new study published in the FASEB Journal reveals that a gene in the blind mole rat, which allows it to thrive in low-oxygen environments, is also active in human tumors. This discovery could lead to the development of new anti-cancer drugs that 'suffocate' tumors.
A new study finds that power can cause individuals to think they have more personal control over outcomes than they actually do. Researchers discovered that those in positions of power are more likely to believe they can influence events beyond their control, resulting in unrealistic optimism and inflated self-esteem.
A study by Dr. Ri-Nan Zheng found that esomeprazole significantly reduced heartburn scores and resolved symptoms faster than omeprazole, lansoprazole, and pantoprazole in patients with reflux esophagitis. The results suggest esomeprazole may be the best choice for symptom relief in these patients.
Research reviews scientific evidence on tooth decay, concluding that good oral hygiene and fluoride toothpaste practices override the effects of food alone. Lifestyle factors such as regular brushing and dental health education are essential in preventing tooth decay.
Research by Christophe Boone and Walter Hendriks found that IT firms with diverse expertise and work experience tend to be more effective in managing organizations. In contrast, personality diversity hinders firm performance. The study suggests using carefully designed personnel selection techniques to screen for knowledge and experience.
A study found that tillage and nutrient management practices can affect soil carbon storage differently depending on the soil profile. When considering only the top 20 cm of soil, no-till treatments showed higher organic carbon stocks, but this effect was cancelled when accounting for deeper soil layers.
The journal Molecular Oncology has been accepted by Thomson Reuters for inclusion in the Science Citation Index Expanded and other prominent databases. It highlights new discoveries and approaches in basic, clinical, and translational research related to cancer.
A study found significant confusion among pre-hospital healthcare providers regarding living wills and DNR orders, which can compromise lifesaving care. Implementing clearly defined code status designations within living wills can clarify this confusion and ensure patient safety.
Researchers have developed a human cell-derived model of ALS, allowing for the study of the disease's progression and potential therapeutics. The model, derived from motor neurons generated from human embryonic stem cells, exhibits characteristics typical of the disease.
A new study describes how telomere dysfunction in skin cells can lead to increased skin cancer risk and pigmentation. Limiting the activity of a tumor suppressor protein, p53, restores cell regeneration but also advances skin cancer progression.
Bias in medical literature can be prevented through recognition and declaration of competing interests, detailed authorship policies, and mechanisms to control outcome reporting bias. The PLoS Medicine editors propose these measures to reestablish the integrity of the scientific record.
A study published in the World Journal of Gastroenterology found that low-dose furazolidone-based quadruple regimens are effective for treating H pylori infection, with eradication rates ranging from 70-90%. The regimens have a low cost and relatively minor side effects, making them a useful option for rescue therapy, particularly in d...
Researchers found that males' mating organs with barbs cause severe injuries to females, but also increase fertilization success rates, outcompeting males with shorter barbs