Articles tagged with Animal Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
Hogfish use their skin to view themselves and fine-tune color changes, a sensory feedback mechanism that lets them monitor their surroundings. Researchers have found light-sensitive opsin proteins in the skin, allowing them to capture changes in light that are filtered through pigment-filled cells.
Neuroscientists have developed new, genetically diverse mouse models to study abnormal tau protein accumulation in the brain, a hallmark of Alzheimer's disease. The study aims to improve research models and understanding of how genetic variations influence neurodegenerative disease development.
Researchers found that birds allowed people to get much closer than expected, with an average distance of just 39 inches, suggesting a significant decrease in fear response. The study's findings challenge existing theories on bird behavior and may offer hope for North American bird populations threatened by human disturbances.
Researchers developed a minimally invasive microneedle platform capable of detecting protein biomarkers in response to immunotherapy against melanoma. The approach integrates with ultra-sensitive single-molecule detection and shows promise for effective drug screening and patient stratification.
Researchers at the Weizmann Institute of Science have identified a novel immune mechanism that enables bacteria to survive on empty batteries, protecting them from viruses. This strategy has been conserved through billions of years of evolution and is also found in advanced species such as corals, bees, and fungi.
A recent study published in Neuron reveals that Noelin proteins play a crucial role in learning and memory formation in the mammalian brain. The study found that these proteins act as 'universal anchors' controlling the distribution and dynamics of AMPA receptors, which are essential for synaptic plasticity.
A new study reveals that using big data and machine learning can improve antimicrobial resistance surveillance in livestock production. The research found correlations between environmental variables, microbial communities, and antimicrobial resistance, suggesting multiple routes for improving surveillance.
A study by Ohio State University found that urban coyote cortisol levels are higher than those in suburban or natural areas. Chronic stress is also linked to poor physical condition, such as mange infection, and the responsibility of running a pack, with alpha individuals experiencing high stress levels.
A recent study found that activating astrocytes in the basal forebrain can keep mice awake for hours without affecting their sleep need or intensity. The researchers hope to develop interventions targeting these cells to improve productivity and health of shift workers and others who work long hours.
A Penn State-led research team discovered that somatostatin signaling acts to dampen communication among cell types in the prefrontal cortex, promoting exploratory and risk-taking-like behavior. The findings suggest that somatostatin fine-tunes circuits to promote certain behaviors, including decision making.
Researchers have found that mouse stem cells mimic their parent animals' cold resistance, generating energy differently at low temperatures. This discovery opens up new avenues for studying organ preservation and human hibernation using in vitro models.
Researchers found that rodents exposed to light for the first time in adulthood showed significant plasticity in their brains, challenging previous beliefs about adult brain rigidity. After a month, their brains looked similar to those of healthy controls, with organized visual responses and smaller receptive fields.
Researchers used radiocarbon dating and time-series modeling to study the timing and causes of megafauna extinctions at Rancho La Brea Tar Pits. The team found that a sharp decline in population occurred between 13,070 to 12,900 years ago, coinciding with warming and drying climate change and increased fires sparked by humans.
A study found that urban great tits have paler plumage than their forest-living counterparts due to inadequate carotenoid intake from city diets. Researchers suggest planting native trees and plants can help provide a healthy diet for these birds.
Researchers have identified a new species of leaf-tailed gecko from northern Madagascar, showcasing its exceptional camouflage skills. The discovery has shed light on the unique characteristics of this species, including its skin flaps and flattened tail.
A study led by Max-Planck-Gesellschaft researchers uncovered the conditions that trigger curiosity in wild orangutans, including social and environmental factors. Young orangutans were more likely to observe and approach novel objects, while the presence of association partners increased their curiosity.
Researchers have discovered that gene therapy may prevent relapse in patients with serious alcohol addiction by altering dopamine function in the brain's mesolimbic reward pathway. The treatment involves sustained release of glial-derived neurotrophic factor (GDNF) in a specific region of the brain.
Researchers discovered a vast array of tardigrade species in Denmark, with unique DNA sequences detected in 96 samples, highlighting their adaptability to various environments. The findings shed light on the incredible survival abilities of these tiny creatures, which can withstand extreme conditions.
Scientists have identified two new mole species in eastern Turkey, belonging to the Talpa genus, which has been living undiscovered for up to 3 million years. The study, using cutting-edge DNA technology, confirms their biological distinctness from other moles in the group.
A new study reveals that mosquitoes use a specific receptor in their ears to modulate their hearing, which is crucial for reproduction and mating. This discovery could lead to the development of novel insecticides or mating disruptors to control mosquito populations and reduce human disease.
Researchers have identified a therapeutic target for Alzheimer's disease by finding that inhibiting an ion pump can slow down cognitive decline and partially restore brain function. The study's findings suggest that maintaining the ion pump could be key to preventing or reversing the disease.
A team of researchers from Keck School of Medicine of USC identified key cells involved in lizard cartilage regeneration and discovered their role in rebuilding cartilage damaged by osteoarthritis. They successfully induced cartilage building in a lizard limb by recreating a tail-like signaling environment.
Researchers at West Virginia University are tracing the cause of diabetic heart disease using diabetic animal models to examine mitochondrial function. They hope to understand how faulty protein import affects the mitochondria and explore potential treatments to improve energy production and reduce cardiovascular risk.
A new study demonstrates that a pill inhibiting a gut enzyme can protect mice from IBD symptoms and preserve intestinal barrier function. The experimental GCPII-inhibiting drug was shown to improve stool consistency, reduce rectal bleeding and inflammation, with no apparent side effects.
A team of researchers has developed a new screening method to identify defective sensors, enabling the mass production of reliable graphene sensors for detecting toxins in water. The sensors can detect multiple contaminants simultaneously and provide early warning for contamination.
Research reveals that a healthy gut microbiome can play a role in the acquisition and severity of HIV and EBV infections. The study found that animals colonized with resident microbiota had higher rates of HIV infection and increased viral loads, suggesting that altering the gut microbiota could be a potential therapeutic approach to c...
A study published in PLOS ONE has discovered parasite eggs in a 200-million-year-old coprolite from Thailand, providing insight into the life of an ancient aquatic predator. The discovery is significant, as it is one of only a few known examples of nematode eggs preserved within the coprolites of Mesozoic animals.
Researchers have identified a protein called Hmga1 that may help prevent bone loss associated with postmenopausal osteoporosis. Increasing the expression of this protein in rats partially reversed bone loss in ovariectomized animals, suggesting its potential as a therapeutic target.
Researchers at Beth Israel Deaconess Medical Center discovered a non-ectodermal and mesodermal origin for large numbers of enteric neurons born after birth. This finding overturns decades of scientific dogma and offers hope for disease-modifying cures to aging patients.
Researchers found that nematode worm larvae can leap through the air and attach themselves to passing insects when exposed to certain electric fields. They observed dauer larvae consistently moving towards the lid of a petri dish, some reaching it in a fraction of a second.
QUT researchers have created a booster vaccine using implant technology to protect wild koalas from Chlamydia disease. The new device allows for in-the-field vaccination without recapturing the animals, reducing human interference and increasing vaccination efficiency.
A new study analyzed ancient DNA from Spanish settlements in the Caribbean and Mexico, revealing that cattle were imported from Africa early in the colonization process. This challenges previous historical records, which suggested cattle were only introduced by Europeans from Europe.
The war in Ukraine has severe consequences for urban wildlife, with 45.1% of Common Noctule bat wintering roosts destroyed or damaged by shelling. This led to the direct killing of approximately 7,000 bats and entrapment of thousands more.
A study reveals that cattle stock tanks can provide crucial water sources for raptors in the Southwestern US, helping them cope with heat stress. The research found that these tanks are used by various raptor species, including barn owls and Swainson's hawks, to drink and bathe.
A new study published in the Journal of Raptor Research found that two colonies of white-rumped vultures in Nepal demonstrated stable reproductive rates over an 11-year period. The number of occupied nests and productivity appeared to be stable, indicating a potential turning point for the critically endangered species.
A new study reveals how Aulacopleura, an ancient sea-dwelling trilobite, developed variable mid-section segments to tolerate dips in local oxygen levels. This adaptation allowed the species to thrive despite being preyed upon by larger predators.
Researchers found that modulating type 1 Interferon (IFN-I) signaling reduces SARS-CoV-2 replication and inflammation in rhesus macaques, offering new treatment strategies for COVID-19. The study also showed a significant reduction in viral loads with IFNmod treatment.
A new study reveals that trumpetfish can conceal themselves by swimming closely behind another fish while hunting, reducing the likelihood of detection. This unique strategy, known as 'shadowing', uses a non-threatening species of fish as camouflage to approach prey.
A new study reveals significant gaps in knowledge of Asian bee species, highlighting the need for more resources to build basic scientific knowledge of bee biodiversity. This knowledge is crucial for managing and maintaining bee diversity, pollination, and food security in Asia.
A 10-year study found that golden-crowned sparrows resettled an average of just 90 feet away from the center of their previous year's range when returning to California after winter migration. The study suggests that social bonds and familiar faces help anchor the birds to specific spaces, even when resources are scarce.
Rice University scientists have developed a tiny, flexible spinal probe system that can record high-quality data from spinal cord neurons and provide localized stimulation. The new tool aims to improve our understanding of spinal cord function and potentially bring new hope to patients with injuries or conditions.
Researchers from Leicester and Nottingham universities have received £600,000 funding to study sexual development and gene shuffling in the malaria parasite. The study aims to uncover new targets for therapies to control disease transmission.
Researchers are creating synthetic microbiomes to protect aquatic environments from bacteria, improving shrimp health and reducing the risk of disease in aquaculture farms. The team is collaborating with farmers in Ecuador to develop new microbial communities that will increase resistance to pathogenic bacteria.
A new study from Wake Forest University School of Medicine found that changes in the gut microbiome significantly impact cocaine use and cravings after withdrawal. The researchers discovered that a depleted microbiome led to increased cocaine-seeking behavior and altered neurobiological markers in reward-related brain structures.
Researchers found that blocking dopamine transporters during mid-adolescence increases adult aggression, impulsivity, and the behavioral response to amphetamine in mice. Artificially stimulating dopaminergic neurons also exacerbated impulsive behavior in tasks. The study suggests potential harm from stimulant exposure in healthy teens ...
Researchers discovered that stimulating dopamine neurons in mice's midbrain triggers orofacial movements, which are linked to brain-wide neuronal activities. The study identified two distinct orofacial movements: transient actions upon reward expectation and active, sustained movements upon receiving a reward.
Researchers propose disease-oriented dosing of rapamycin to delay age-related diseases and increase lifespan. By decelerating early development of these diseases, rapamycin may help individuals live longer.
A study published in PLOS ONE found a significant surge in bird feeding interest worldwide during the pandemic, with countries having higher bird diversity exhibiting more Google search activity. The researchers analyzed data from 115 countries and found an average increase of 511 bird species in countries with higher search interest.
Sea urchins struggle to 'get a grip' as climate change causes lower salinity levels, affecting their ability to attach to surfaces. The study found that low salinity conditions negatively impact righting response, movement, and adhesive ability.
A team of scientists has successfully elucidated the structure and function of LITE-1, a biomolecule used by Caenorhabditis elegans to detect danger. The researchers used artificial intelligence to predict the structure of LITE-1, which is a channel protein that forms a pore in the cell membrane allowing charged particles to pass through.
Researchers aim to treat pancreatic ductal adenocarcinoma by targeting amino acid transporter SLC6A14 and compensatory nutrient scavenging mechanisms autophagy and macropinocytosis. Using alpha-methyl-L-tryptophan and hydroxychlorquine, the study seeks to improve therapeutic outcomes in patients with pancreatic cancer.
Researchers found that invasive red swamp crayfish populations in Japan developed genetic changes enhancing cold resistance, including changes in the protective outer layer and peptidase inhibitors. These findings provide insights into molecular mechanisms of invasive species and may have potential medical applications.
Researchers developed a novel maze design that allows for the tracking of mice's navigational strategies, revealing three primary approaches: random, spatial, and serial search. The study provides valuable insights into how animals select these strategies based on environmental factors.
A recent study published in Nature Mental Health emphasizes the need for further research on sex differences in depression. The study, led by Georgia Hodes and Dawson Kropp, aims to uncover effective and sex-specific biomarkers for depression onset and target better treatment options.
Researchers at North Carolina State University identified a specific blend of pheromone chemicals used by male moths during courtship, including an aphrodisiac called methyl salicylate. Female moths can recognize this chemical through two smell receptors, and its presence in males' hairpencils is linked to mating success.
A new study led by UNSW Sydney reveals the pygmy right whale's behavior is quite different from its larger relatives, with no long-distance migrations to Antarctic waters. The whales instead remain in mid-latitude waters off southern Australia, feeding on krill and copepods throughout the year.
Researchers have identified a genetic cause for virgin birth in female flies, allowing them to reproduce without males. The ability is passed down through generations of females and can be induced in an animal that usually reproduces sexually.
A study published in Neuron found that a structure in rat brains called the periaqueductal gray is essential for play and laughter. The researchers used tickling to simulate playful environments and measured brain activity, finding strong neural responses to both tickling and playing.
Researchers found that Period 1 gene becomes more active in memory-forming region of brain in daylight hours after learning, playing crucial role in consolidating memories. Mice exhibit improved daytime memory performance compared to nighttime.
Researchers from Sahmyook University found that phyllodulcin, a natural sweetener found in hydrangeas, can efficiently inhibit amyloid beta (Aβ) aggregation and dissociate its aggregates in an animal model study. The study suggests that phyllodulcin may be useful in delaying the onset and progression of Alzheimer's disease.