Articles tagged with Basic Research
NTU Singapore has expanded its research collaborations with French partners to push the boundaries of science. The university has inked six new partnerships and renewed existing collaborations across various fields, including quantum physics, nuclear energy, and sustainability.
The Marine Biological Laboratory (MBL) has been awarded $4.3 million by the Massachusetts Life Sciences Center to expand its imaging capabilities. The grant will support the procurement of two state-of-the-art microscopes that can perform advanced imaging techniques, including 2D and 3D reconstruction from electron and light microscopy.
Researchers at Sainsbury Wellcome Centre find frontal and parietal cortex play key role in encoding value of economic choices when faced with uncertainty. The study provides foundation for understanding neurobiology of risky decisions.
The WVU School of Medicine and Benjamin M. Statler College of Engineering and Mineral Resources will support clinical trials and engineering technology development. The project aims to improve care and rehabilitation for people with neurological disorders through novel physician-engineer programs and human research.
Researchers identify mechanism by which specific protein condensates transition from liquid to solid states, enabling stability and transmission of mechanical forces. MEC-2 proteins' biological function switches with rigidity maturation, facilitating mechanosensation.
A team of researchers aims to develop drug therapies by targeting genes that affect metabolism in people with Down syndrome, potentially improving their quality of life. The project will focus on the protein SIM2, which has been linked to breast cancer and metabolic changes in individuals with the condition.
Research suggests that eating habits in winter may be better for metabolic health than in summer, especially in mice exposed to 'winter light'. The study found that these mice had less body weight gain and more rhythmic eating patterns, leading to benefits in metabolic health. Further studies in humans are needed to confirm this finding.
The High Performance Data Facility Hub will provide researchers with unprecedented data management resources, accelerating scientific discovery through seamless access to large and complex datasets. The hub will be led by Jefferson Lab and partner with Lawrence Berkeley National Laboratory.
Two parallel projects publish detailed cell atlases of the adult human brain and brain development, revealing over 3,000 cell types, including new insights into brain diseases and potential therapeutic targets. The freely available brain atlases will enable researchers to compare healthy brains with diseased ones.
Researchers at UTSA have been awarded a grant to develop a new technology that converts carbon dioxide into a raw material for producing chemical products. The project has the potential to create a productive area of catalysis research and reduce greenhouse emissions.
Researchers at the Francis Crick Institute found that pregnancy hormones oestrogen and progesterone act on a small population of neurons in the brain to switch on parental behaviour. This adaptation results in stronger and more selective responses to pups, enabling mothers to care for their young.
Researchers at Washington State University have made a groundbreaking discovery about the Fischer Tropsch process, a key step in converting coal, natural gas, and biomass into liquid fuels. The team found that the process exhibits self-sustained oscillations, which can be harnessed to enhance reaction rates and product yields.
Researchers from Imperial College London and the University of Nottingham used machine learning to identify 'atomic shapes' that form basic pieces of geometry in higher dimensions. The findings reveal unexpected patterns in these shapes and demonstrate the potential for machine learning to accelerate mathematical discoveries.
Holford's research will focus on developing new directions for using cephalopod venoms in drug discovery and exploring their evolutionary dynamics. Her study has broad applications for science, including understanding venom gland biology and the molecular mechanisms behind bioactive compounds.
Researchers identified key proteins regulating cholesterol distribution within cells, including OSBP1, ORP92, and GRAMD1s. This discovery sheds light on the critical mechanisms underlying cellular cholesterol distribution, offering insights into various health conditions.
Heart cells in developing zebrafish transition from silence to beating in a simultaneous, coordinated manner. Each cell can beat independently, and the heartbeat starts from different locations in different zebrafish.
Researchers at UMass Amherst have identified a small strand of microRNA called let-7 as crucial in governing the formation of cellular memories that enable T-cells to recognize and attack tumor cells. This discovery offers new insights into how vaccines work and could lead to improved cancer therapies by boosting cellular memory.
A study by Annenberg Public Policy Center researchers identifies five factors assessing science's self-presentation and their impact on public support for increasing US science funding. The factors capture differences between conservatives' and liberals' perceptions of science, highlighting key differences in what matters to each group.
Researchers warn that greenwashing poses a threat to achieving a 'nature positive' world, where environmental decline halts and biodiversity improves. The University of Queensland study emphasizes the need for standards and transparency to distinguish genuine efforts from misleading claims.
A new study published in Virology Journal confirms 25 different types of HPV prevalent in Nigeria, highlighting the need for region-specific vaccines. The discovery underscores the limitations of existing vaccines like Gardasil-9, which only protects against nine cancer-causing types.
Jennifer Kane is studying how microbes interact with Miscanthus roots to boost productivity and sustainability. The research aims to understand what conditions enable the plant to prosper, with potential implications for bioenergy production on marginal lands.
The NIH has released a strategic plan for research on herpes simplex virus 1 and 2, outlining four priorities: improving fundamental knowledge, accelerating diagnosis, treating HSV while seeking a curative therapeutic, and preventing infection. The plan aims to reduce the burden of HSV-1 and HSV-2 in the US.
The project aims to assess the operational resilience of microgrids on DoD installations and ships, using new operational resilience indexes developed by Lehigh University researcher Javad Khazaei. The team will develop a dashboard to monitor resilience indexes in real-time, providing recommendations for improving the systems.
The newly upgraded Linac Coherent Light Source (LCLS) at SLAC National Accelerator Laboratory successfully produced its first X-rays, ushering in a new era of research. Scientists will now be able to examine quantum materials with unprecedented resolution and study biological molecules to develop new pharmaceuticals.
Researchers discovered NSMF protein's role in alleviating DNA replication stress by displacing weakly bound RPA proteins and promoting phosphorylation. This mechanism accelerates relief of replication stress, offering a new direction for treating various diseases, including cancer and age-related conditions.
Researchers discovered a potential new target for treating metastatic cancer by blocking the cytosol-to-mitochondria citrate flux process, which induces oxidative stress and cell death. The study's findings provide additional data to support therapy targeting this process for cancer patients with metastasis.
Researchers used a new analytical approach to understand how the brain controls movement and eye stability in zebrafish. By analyzing neuronal activity, they identified two main features that correspond to specific types of movements, including eye rotation and body positioning.
Researchers at Johannes Gutenberg University Mainz have successfully measured the energy of electrons produced in tritium beta decay, allowing them to set a first upper limit on neutrino mass using 'CRES' technology. The method involves detecting microwave radiation emitted by electrons as they travel in a magnetic field.
Researchers have generated nearly deterministic OAM-based entangled states using QDs, enabling hybrid entanglement states in high-dimensional Hilbert spaces. This breakthrough offers a bridge between photonic technologies for quantum advancements.
A groundbreaking study from the University of Copenhagen sheds light on the significance of transmitting epigenetic information during cell division for proper function of embryonic stem cells. The researchers found that histones play a crucial role in maintaining epigenome stability and cell identity.
Researchers aim to identify genetic risk factors and mechanisms underlying virus-induced asthma, using artificial intelligence-based techniques and patient-derived models. The study may lead to personalized prevention campaigns and mechanism-targeted drugs.
Researchers at ISTA discovered that immune cells actively shape their environment by consuming chemokine signals, allowing them to generate their own guidance cues. This dynamic regulation enables collective migration of immune cells and has significant implications for enhancing immune response coordination.
The editorial discusses epigenetic mechanisms leading to oocyte quality loss, a significant factor in age-related fertility decline. Researchers highlight the importance of understanding this process to address the growing issue of advanced maternal age and its impact on reproduction.
A new study analyzing over 220,000 people's sleep data shows that those in Asia have shorter sleep duration and lower quality, with more variable sleep timing on weekdays. In contrast, people in other regions tend to have longer weekend sleep extension, suggesting a cultural impact on sleep habits.
The Norwegian approach to prison reform focuses on building relationships and trust, reducing solitary confinement. In a US pilot program, residents spent more time outside their cells, with a 74% drop in assaults and an 86% decrease in staff use-of-force incidents.
Augusta University researcher Arni S.R. Srinivasa Rao calls for updating the UN's traditional approach to measuring population replacement levels. He proposes a new formula that allows for more timely and accurate measurement, which is essential for understanding emerging global demographics.
Scientists have successfully measured the speed of molecular charge migration in a carbon-chain molecule, revealing a movement of several angstroms per femtosecond. The study used a two-color high harmonic spectroscopy scheme with machine learning reconstruction to achieve a temporal resolution of 50 as.
The series emphasizes the importance of anesthesiologists in addressing unmet needs of patients with Substance Use Disorder (SUDs) in the perioperative period. Anesthesiologists are urged to adopt a broader approach to effective disease management, incorporating trauma-informed patient care and increased collaboration with addiction me...
Researchers from Aalto University have successfully detected a triplon, a quantum entanglement wave, in an artificial quantum magnet created using small organic molecules. This achievement marks the first direct observation of triplons using real-space measurements.
Researchers from The University of Warwick and The University of Manchester have solved the long-standing puzzle of why graphene is permeable to protons. Protons are strongly accelerated around nanoscale wrinkles in perfect graphene crystals, which could lead to more sustainable hydrogen production.
A team of engineers at Brown University discovered that drag on partially submerged objects can be three or four times greater than on fully submerged objects. The study found that the level of water repellency plays a key role in drag forces, with superhydrophobic materials encountering more drag.
Researchers explore nucleon resonances, gaining insight into early universe's chaotic state. The experiment provides new information on the 3D structure of resonating protons and neutrons.
Researchers from the University of Kansas have created a powerful dataset to facilitate drug development against gram-negative bacteria. The dataset reveals over 270,000 previously unidentified outer-membrane proteins with potential as vaccine targets.
A recent study published in Neuron reveals that Noelin proteins play a crucial role in learning and memory formation in the mammalian brain. The study found that these proteins act as 'universal anchors' controlling the distribution and dynamics of AMPA receptors, which are essential for synaptic plasticity.
Researchers from the Wellcome Sanger Institute mapped the multiple organ functions of the human yolk sac, revealing its role in producing key hormones and blood cells. The study provides novel insights into the earliest stages of immune cell development and has implications for understanding childhood diseases.
Printable electronics have potential in solar power and LED screens but face challenges in scalable manufacturing. Professor Adam Printz is using a new RAPID printing process to examine fundamental characteristics and advance the field.
Researchers found that liraglutide improves associative learning in people with obesity by restoring brain activity to normal-weight levels. The study showed that participants with obesity had reduced ability to associate sensory stimuli and decreased brain activity compared to those with normal weight.
Aerodynamic researchers at University of Illinois create wind tunnel experiment to study internal boundary layers and their impact on flow behavior. They identify a new internal boundary layer that changes the flow's behavior, providing insights into aerodynamics physics and improving turbulence models for complex designs.
Researchers from University of Freiburg and University of Cambridge have observed dynamic molecular aggregates in cells for the first time. These condensates play a crucial role in controlling biochemical processes and are regulated by active biological mechanisms, not just physical forces.
Researchers have identified key genes involved in producing large amounts of immunoglobulin G, a crucial antibody in the human body. The discovery could lead to advancements in manufacturing antibody-based therapies for diseases such as cancer and arthritis.
Scientists at the Boyce Thompson Institute have constructed a comprehensive 'super-pangenome' for watermelon and its wild relatives, uncovering beneficial genes lost during domestication. This genetic toolkit can be used to develop varieties with enhanced yield, increased disease resistance, and improved adaptability.
A new technique combining ultrafast physics and spectroscopy reveals the dance of molecular 'coherence' in unprecedented clarity. This shows a vibrational effect, rather than motion for the functional part of the biological reaction that follows.
The newly expanded NSF Center for the Mechanical Control of Chemistry will investigate atomic-scale mysteries of crushing chemistry, enabling new advances in chemistry. The center will provide insights necessary for scaling up mechanical chemistry research across the US.
Researchers at the Marine Biological Laboratory have devised a method to precisely alter rotifer genomes using CRISPR-Cas9, enabling the study of fundamental biology and evolution. The new approach will allow scientists to investigate various aspects of biology, including aging, DNA repair mechanisms, and mitochondrial function.
A protein found in bacteria activates its enzymatic activity by up to 10,000 times when exposed to blue light, acting like an on-off switch. This discovery could lead to enhanced and optimized optogenetic tools and medical treatments.
Researchers at North Carolina State University have developed a robotic gripping device that can handle ultrasoft, ultrathin, and heavy objects with excellent balance of strength, precision, and gentleness. The design uses kirigami and can be fabricated from biodegradable materials.
Researchers have successfully grown high-quality single-crystalline T-Nb2O5 thin films with two-dimensional vertical ionic transport channels, enabling fast and dramatic changes in electrical properties. The material undergoes a significant electrical change upon Li insertion, allowing it to switch from an insulator to a metal.
Researchers used supercomputers to predict the spatial distributions of charges, momentum, and other properties of 'up' and 'down' quarks within protons. The results revealed key differences in the characteristics of the up and down quarks, implying different contributions to the proton's fundamental properties.
Researchers have observed unusual waves of charge within a crystal of uranium ditelluride, a previously unseen facet of its superconductivity. The findings reveal a static variation in two different properties: one related to charge and the other to interacting electron pairs.
The study reveals that metallic lithium forms a rhombic dodecahedron in the absence of corrosion, which could lead to safer lithium-metal batteries with increased performance. The researchers developed a new technique for depositing lithium faster than corrosion forms, allowing them to observe this unique shape.