Articles tagged with Basic Research
The U.S. Department of Energy has selected Kate Petersen Mace as the project director for the High Performance Data Facility (HPDF), a first-of-its-kind project providing resources for data-intensive science. Mace will lead the team in developing transformational capabilities to serve the DOE community.
A new microscope-integrated OCT system has been developed to identify tumor margins during brain surgery, providing high-resolution images of subsurface anatomy. The system has shown promising results in clinical studies, with the potential to improve outcomes for neurosurgery procedures.
A new study by Tel Aviv University reveals that 27% of respondents withhold inventions due to reasons such as emotional attachment, fear of credit, or lack of trust in management. The study aims to shed light on this phenomenon and develop effective management tools to increase employees' willingness to disclose their inventions.
A team of researchers has made groundbreaking findings that suggest our cosmic neighborhood may be far larger than previously thought. The study, which analyzed the movements of 56,000 galaxies, reveals a potential shift in the scale of our galactic basin of attraction.
Researchers induced fast switching between electrically neutral and charged luminescent particles in an ultra-thin, two-dimensional material. The result opens up new perspectives for optical data processing and flexible detectors.
Researchers at UBC Okanagan challenge assumptions about the validity and suitability of high-intensity interval training (HIIT) for public health. They argue that evidence-based findings show HIIT is enjoyable and effective for a wide range of populations, despite critics' claims.
A researcher at UTA is developing a tracer tool to help water suppliers ensure safe and reliable drinking water during extreme weather events. The tool will enable better management of drinking water in Tarrant County, addressing concerns about water flow and distribution.
A University of Virginia engineer developed a workflow to combine advanced imaging technologies for improved understanding of porous bone, which could inform disease detection. The method allows for three-dimensional rendering of bone structure across various length scales.
A Dartmouth-led study found that air pollution from fossil fuels reaches the remote Arctic, altering its fundamental atmospheric chemistry. The researchers detected declines in methanesulfonic acid, a biomarker linked to phytoplankton productivity, which plummeted in environments high in emissions.
A study published in Neuron found that psychedelics, such as DOI, activate fast-spiking interneurons in the ventral hippocampus, which helps to silence other neighboring neurons and reduce anxiety in mice and rats. This understanding of brain chemistry could lead to the development of new drugs targeting anxiety.
A new experimental technique directly measures heating in spintronic devices, allowing researchers to compare thermal effects to electromagnetic interactions. The study finds that heating has a significant impact on antiferromagnetic materials used in spintronics, but the effect depends on the physics responsible.
A Virginia Tech research team has identified a molecular mechanism by which Shigella flexneri bacteria manipulate host molecules to ensure their survival. The study provides a new understanding of the infection pathway and its potential implications for preventing similar infections in other bacteria.
Researchers have identified a protein, RNF114, that reverses cataracts by facilitating protein degradation. This discovery may lead to a surgery-free treatment strategy for managing cataracts, a common cause of vision loss worldwide.
A large-scale study will enroll 1,000 patients with acute Lyme disease to identify causes of prolonged symptoms. The research team aims to shed light on why some return to good health and others develop debilitating symptoms.
A recent study discovered that COI1 proteins in maize balance growth and defense by degrading JAZ and DELLAs. This finding could lead to developing more resilient maize varieties. The research revealed an unexpected role of COI1 in regulating DELLA levels, enabling maize to thrive under hot and arid climates.
Researchers at Chalmers University of Technology have made a significant step in understanding the fundamental constraints on noise, paving the way for future nanoelectronics. The study investigated thermoelectric heat engines at the nanoscale and found a critical trade-off between noise and power.
Researchers have found two distinct maps in the brain's secondary motor cortex that enable spatial planning and navigation, with implications for understanding neurological conditions such as stroke. The study discovered a self-centred map used for planning actions and a world-centred map used to determine body position in the world.
A study at the University of Bonn has revealed that fly larvae have special sensors triggered by swallowing, releasing serotonin to continue eating. This control circuit may also exist in humans and could help understand eating disorders such as anorexia or binge eating.
A new study proposes that early dark energy could explain the formation of numerous bright galaxies in the early universe, resolving the 'Hubble tension' puzzle. The team modeled galaxy formation with a brief appearance of early dark energy, finding it fits observations and solves both puzzles.
A new study by Magnus Nordborg's group reveals unique transcriptional regulation mechanisms in plants, distinct from those found in animals and yeast. The researchers identified a critical regulatory sequence motif, GATC, that fine-tunes gene expression across different cell types.
Researchers Gavin Cornwell, Sneha Couvillion, and Bo Peng will study bioparticles, soil microbes, and their impact on climate models. They aim to improve representations of ice nucleating particles and understand lipid exchange in soil ecosystems.
Neuroscientists have discovered a global process across the brain that coordinates sensory input with motor action through learning. In trained mice, neurons link sensory evidence to action initiation, integrating information across multiple brain regions.
A recent study reviews the intricate biosynthesis and regulation of ginsenosides in Panax notoginseng, highlighting key enzymes and transcription factors. The findings support breeding superior varieties and optimization of production techniques to enhance ginsenoside quality and production.
Oak Ridge National Laboratory scientist Matthew Loyd has been selected for a DOE Early Career Research award to develop a high-count-rate, high-resolution neutron camera. The detector will improve neutron detection at high count rates and enable observing weak data signals in experiments.
Researchers have successfully visualized and tracked specific cells in deep brain tissue, including along the corpus callosum's nerve fibre highway. This advancement could potentially lead to better diagnostic tools for glioblastoma, a deadly brain cancer.
A new method called VitelloTag has been developed at the Marine Biological Laboratory, allowing researchers to deliver miniature research tools into egg cells and embryos. The approach uses a yolk protein found in most animals to bind to the receptor on the egg cell surface, enabling efficient delivery of CRISPR-Cas9.
Researchers have proposed a novel treatment strategy for post-acute infectious syndromes (PAIS), including Long COVID. The multimodal approach combines pharmacological interventions like metformin and low-dose naltrexone with physical therapies like extracorporeal apheresis.
A recent study published in Nature questions the scientific validity of the long-held claim that 80% of the world's biodiversity is found in Indigenous Peoples' territories. The research highlights the need to correct this figure, as it oversimplifies the complex relationship between Indigenous Peoples and biodiversity.
The Journal of Bioresources and Bioproducts is a leading open access journal fostering transformative research on bioresource conversion into biomaterials, biochemicals, and bioenergy. The journal's eight thematic areas focus on cutting-edge topics in sustainable energy and materials science.
A novel synthetic biology platform enables rapid and cost-effective transformation of protein binders into high-contrast nanosensors for various applications. The platform uses fluorogenic amino acids to increase fluorescence up to 100-fold, enabling the detection of specific proteins, peptides, and small molecules.
Researchers unveil previously unseen properties of neutron stars through gravitational wave analysis, providing insight into internal composition and dynamic material properties. The study places observational constraints on viscosity within neutron stars.
Researchers from Medical University of Vienna discovered that TRPV1 is the primary detector of noxious heat in humans, but other molecular mechanisms contribute to protective heat avoidance. The findings have significant implications for research into heat damage prevention and potential new therapies.
A new 'deep scanning' approach reveals that individuals with depression have a larger salience network in the frontal cortex and striatum, increasing their risk for depression. This finding suggests that people may be pre-wired for depression if they have this brain feature in childhood.
Scientists at TU Wien and JILA/NIST have successfully created the world's first nuclear clock, leveraging thorium atomic nuclei to achieve ultra-high precision measurements. The breakthrough combines a high-precision optical atomic clock with a high-energy laser system, setting the stage for future improvements in precision.
Researchers from Niigata University have developed novel glass-forming liquid electrolytes with high ion conduction and efficiency. These materials offer unique advantages in terms of efficiency and application-specific adaptability, paving the way for next-generation energy storage devices.
Researchers have found a new brain mechanism that detects prediction errors between expected and actual sensory inputs, boosting responses to unexpected information. This discovery could offer insights into the neural circuits underlying autism spectrum disorders (ASDs) and schizophrenia spectrum disorders (SSDs).
Scientists discovered the highest natural blood sugar levels in mammals, found in a species of bats that can survive on a diet rich in sugars. The study's findings suggest that these bats have evolved unique strategies for glucose regulation, which may hold potential for managing metabolic diseases in humans.
The LZ experiment has narrowed down possibilities for weakly interacting massive particles (WIMPs), a leading candidate for dark matter. The new results explore weaker interactions than ever searched before and limit what WIMPs could be, finding no evidence above a mass of 9 GeV/c².
The gift will support the expansion of the Vagelos-funded institute, construction of a new biomedical research building, and innovative collaborations in cell engineering and gene therapy. This investment aims to revolutionize treatment for various diseases, representing a new paradigm in medicine.
A University of Central Florida researcher has developed a nature-inspired filtration and conversion system that extracts carbon dioxide gas from the atmosphere to create fuels and chemicals. The device mimics the lotus surface, capturing carbon dioxide with a microsurface comprised of a tin oxide film and fluorine layer.
A team of researchers at UC Davis Health discovered a novel bioelectrical mechanism that allows Salmonella bacteria to navigate the gut lining and find vulnerable entry points. The study found that Salmonella bacteria detect electric signals in FAE, which helps them move towards openings in the gut where they can enter.
Scientists at the University of Augsburg have found that macrophages, also known as scavenger cells, form in the vitreous body of the mouse eye during embryonic development. This new understanding could lead to therapies for diseases like diabetic retinopathy and prenatal vessel defects.
A recent study evaluates eight widely-used solar-induced chlorophyll fluorescence (SIF) products to identify the most accurate tools for tracking global vegetation productivity and phenology. The research finds that Global OCO-2 SIF (GOSIF) and Contiguous Solar-Induced Fluorescence (CSIF) datasets excel in capturing spatiotemporal vari...
A team of researchers from Tokyo Institute of Technology elucidated the mechanisms of electron transfer in upconversion organic light-emitting diodes, resulting in improved efficiency. They discovered a novel donor-acceptor combination that led to the fabrication of an efficient blue UC-OLED with an extremely low turn-on voltage.
A new study published in Physical Review Letters suggests that nanohertz gravitational waves may not originate from supercool first-order phase transitions. Researchers found that such transitions would struggle to complete, shifting the frequency of the waves away from nanohertz frequencies.
A new study from UCSF finds that child-parent psychotherapy can reduce biological age acceleration in children who have experienced trauma. The treatment group showed significantly less age-related change than the comparison group, with potential implications for long-term health outcomes.
A study published in Cell reveals that Mrc1 is crucial for epigenetic inheritance, ensuring cells maintain their genetic identity and function. The discovery has significant implications for understanding diseases like cancer and aging, where epigenetic landscapes deteriorate over time.
A WVU biologist is studying how genes establish animal body plans and contribute to regenerative abilities. He has identified Hox genes as key players in planarian regeneration, suggesting their functions may differ in highly regenerative versus poorly regenerative organisms.
Guan's lab will apply accumulated experience and methods to study SLC6A14, a sodium-coupled epithelial amino acid co-transporter involved in cancer and several chronic diseases. CryoEM will be used to determine the structure of SLC6A14, providing insight into its substrate specificity and inhibitory mechanisms.
Mary Bishai, a Brookhaven physicist, has been recognized as a Distinguished Scientist Fellow by the DOE Office of Science. Her work on understanding neutrinos' properties has led to extraordinary leadership and service to the particle physics community. As a mentor, she is guiding the next generation of researchers.
Researchers at Carnegie Mellon University propose guidelines for using interpretable machine learning methods in computational biology to tackle complex problems. The guidelines address pitfalls such as relying on a single method and cherry-picking results, emphasizing the need for multiple approaches and human-centric considerations.
A study published in Nature Metabolism reveals neural circuits in the mouse brain that promote hunger-driven feeding and suppress pleasure-driven eating. The discovery of a specific group of neurons called diagonal band of Broca (DBB) Penk neurons that regulates balanced feeding is promising for developing strategies to combat obesity.
Researchers found that children's immune systems attacked their own tissues after latching onto a coronavirus protein resembling one found in multiple organs. Early intervention was crucial to prevent death in these cases, and the study has implications for understanding other autoimmune diseases.
Researchers found that dopamine treatment increased neprilysin levels and reduced beta-amyloid plaques in mouse brains, improving memory function. Long-term L-DOPA treatment also showed improved cognitive performance in mice.
Researchers developed a new technique to study charge density waves in materials, revealing two previously unobserved ways electricity can manipulate their state. The method allows for the observation of nanoscale lengths and nanosecond speeds, with potential applications in energy-efficient microelectronics.
Researchers developed a method to produce cobalt nanoparticles with controlled crystal phase, leading to higher selectivity and efficiency in hydrogenation reactions. The study showcases the potential of abundant cobalt as an alternative to noble metal catalysts.
Researchers have gained new insights into the cellular reactions to a cerebral infarction, identifying specific cell types and their roles in the early phase after a stroke. The study's findings hold promise for developing novel therapeutic strategies to promote nerve tissue regeneration after a stroke.
A new microscopy method, Tempo STEM, significantly reduces radiation required by 'shutting off' the beam at peak efficiency. This approach eliminates excess damaging irradiation and avoids sample transformation or destruction.
Researchers at the University of Bath have discovered a new optical phenomenon called hyper-Raman, which can penetrate deeper into living tissue and yield images with better contrast. This effect has significant potential applications in pharmaceutical science, security, forensics, environmental science, art conservation, and medicine.
Xiao-Qing Yang, a physicist at Brookhaven National Laboratory, has spent his career studying and improving battery materials using advanced characterization tools. His work has led to a fundamental understanding of the relationship between structure and performance in battery systems.