Articles tagged with Discovery Research
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study published in The Journal of the National Cancer Institute found that patients with high intra-tumour heterogeneity of the oestrogen receptor are twice as likely to die from breast cancer over a span of 25 years. This risk holds true for Luminal A breast cancer subtype, which is generally considered to have a good prognosis.
US Army Research Laboratory scientists improved chemical yield of diaminoglyoxime (DAG) synthesis by 80%, increasing material production per reaction. The new method reduces heat release, minimizing explosion and combustion hazards.
A study by Bar-Ilan University researchers found that difficult relationships are common, especially within families and workplaces. The study, based on data from the University of California Network Study, reveals that social norms and institutional constraints often force people to retain challenging connections.
Researchers at University of Texas at Austin analyzed 40 years of stock prices, finding that high-beta stocks do not outperform those with low betas. Controlling for lottery-like characteristics, the seminal theory is empirically supported, revealing price pressure from investors as the main cause of the anomaly.
The AGA FMT National Registry is the largest planned FMT study, tracking 4,000 patients for 10 years. The registry aims to provide a wealth of data on FMT's effectiveness and long-term effects, helping advance research and improve treatment outcomes.
The Renown Institute for Health Innovation is partnering with Helix to offer DNA sequencing to an additional 40,000 Nevadans through the Healthy Nevada Project. This phase will utilize Helix's proprietary Next Generation Sequencing technology to provide unparalleled access to genetic data.
Three new species of zoantharians were discovered in the Indo-Pacific region, expanding our understanding of coral reef diversity. One species was named after President Tommy Remengesau of Palau, highlighting the nation's support for marine conservation.
The Genetic Information Nondiscrimination Act (GINA) created an individual access right to genomic data, but its implementation has been marred by controversy and conflicting regulations. Bioethicists and safety regulators have raised concerns about the misuse of genetic data, while lawmakers argue that GINA solves a non-existent problem.
Researchers at Washington State University discovered a genetic variation that predicts how well people perform certain mental tasks when sleep-deprived. Individuals with a specific variation of the DRD2 gene are resilient to the effects of sleep deprivation on cognitive flexibility.
Researchers at Monash University have identified a novel molecular 'blueprint' that enables the immune system to fight disease by 'remembering' past infections. This discovery potentially opens new avenues for improving vaccines and therapies, including those targeting cancer and autoimmune diseases.
Researchers at Eurac Research and Medical University of Innsbruck have identified a new medical entity: isolated high-altitude psychosis. The condition is characterized by psychotic episodes in extreme altitudes, often accompanied by hallucinations and disorientation.
A comprehensive study revealed that the common silky anteater is actually a complex of at least seven different species, including three previously revalidated and three newly described species. The discovery was made using genetic and anatomical data from 33 DNA samples and over 280 museum specimens.
Researchers at the University of Alberta have developed a new way to produce high-density DC current, vastly improving over existing triboelectric nanogenerators. The discovery enables continuous flow of electricity from nanoscale movement and vibration, opening up potential applications in sensors, wearable devices, and more.
A large genetic study found a significant link between delay discounting and ADHD, obesity. Delay discounting refers to the tendency to undervalue future rewards, which was found to be correlated with various psychiatric and behavioral traits.
After retiring from work life, people sleep approximately 20 minutes longer than before retirement and experience improved sleep quality. This is particularly true for individuals who had previously experienced sleep difficulties or were heavy alcohol users, with a notable decrease in early morning awakenings and nonrestorative sleep.
Researchers have discovered two super-Earths around the red dwarf star K2-18, one of which could be a scaled-up version of our own planet. The newly found planet, K2-18c, is likely too hot to support life, but its companion, K2-18b, has potential for liquid surface water and might harbor conditions suitable for life.
Researchers at Toyohashi University of Technology have successfully recorded non-error data in magnetic holographic memory, reducing energy consumption and improving reconstruction performance. The breakthrough enables high-volume data storage with ultra-high density and speed, potentially surpassing Blu-ray discs.
A team from Peking University successfully experimentally demonstrated a 70Gb/s optical link using an 18GHz band-limited VCSEL and multimode fibers. This achievement showcases the potential for realizing high-speed data transmission in data centers using low-cost and band-limited devices. The study's results have important scientific s...
Female horseflies can identify dark cows among equally dark patches using polarized light reflected from their smooth coats. This allows them to detect host animals more efficiently in sunny conditions.
Researchers at The Feinstein Institute discovered dozens of genetic variations linked to general cognitive ability. These findings have the potential to aid in targeted treatment for cognitive disorders, including Alzheimer's disease, schizophrenia, and attention deficit hyperactivity disorder.
Researchers identified AMIGO2 and PTK7 as key players in melanoma cell growth and survival. Targeting these proteins may lead to new treatments for metastatic melanoma.
Researchers from Insilico Medicine and BitFury Group present a blockchain-based life data interchange system to decentralize and accelerate biomedical research. The system utilizes deep learning technologies to analyze human life data, reducing biases and democratizing healthcare access.
New study reveals that five babies per 1,000 born in England may have sustained brain injury at or soon after birth, leading to serious conditions like cerebral palsy and blindness. The research, using routine NHS data, aims to better understand how to prevent brain injuries in preterm and full-term babies.
A new method developed by researchers at the University of Warwick uses fluorescent dye to detect small microplastics in oceans, challenging current estimates that only 1% of plastic waste is found. The method reveals a significant abundance of polypropylene microplastics, highlighting the impact of consumer habits on ocean health.
A new analytical method developed at GEOMAR Helmholtz Centre for Ocean Research Kiel shows that water penetrates significantly deeper into the Earth's crust than previously assumed. This finding is crucial for understanding the ocean's heat budget and volatiles in the crust.
Galla Chinensis has been identified as a strong potential agent in preventing dental caries due to its antibacterial capacity and tooth mineralization benefit. The main active ingredient of Galla Chinensis is unknown, but medium molecular weight gallotannins have been shown to be most effective.
A new model proposes returning control over human life data to patients, accelerating biomedical research through a secure and transparent distributed personal data marketplace utilizing blockchain and deep learning technologies. This approach can resolve challenges faced by regulators and improve patient satisfaction.
Researchers analyzed anonymous Google location data to understand human mobility patterns before and after Hurricane Maria. Travel out of Puerto Rico increased by 20% the day before the storm, with people flocking to cities like Orlando and Miami for shelter.
Researchers at Tokyo Metropolitan University have discovered a novel layered superconductor based on tin and arsenic, exhibiting high-temperature superconductivity. The material's crystal structure and electronic state are unique, enabling the study of high-temperature superconductivity.
The American Heart Association has awarded $2 million in grants to researchers, clinicians and computer engineers to develop precision medicine projects. The grants will support the use of cloud computing and data analytics to improve cardiovascular disease prevention and treatment.
Researchers found that beta wave activity is not sustained but rather occurs in discrete bursts, and the timing of these bursts affects perception. The study's findings provide a better understanding of how beta waves help filter distractions to process sensations.
The NIH has awarded Jackson Laboratory for its innovative software to improve data sharing in heart disease research. Researchers will now have access to genomic data shared by humans and animal models, enabling them to fast-track their studies.
Researchers at UC Davis are part of a NIH initiative to make biomedical data accessible online. The goal is to accelerate discoveries by making research data FAIR, findable, accessible, interoperable, and reusable.
Researchers at University of California San Diego have found a new pathway called Intracellular Pathogen Response (IPR) that helps animals cope with certain types of stress and attacks, including heat shock. The study reveals the IPR gene pals-22, which increases tolerance to heat shock when expressed in roundworms.
Researchers found signals in a tiny worm that control the mechanism of severed nerves self-healing. The discovery enables genetic control over this process, raising hopes for treating nerve injuries in humans. The study used laser beams to sever neurons and observed how they regenerated, finding full function restored within 48 hours.
Researchers at UHN's Krembil Research Institute identified LXB4, a unique lipid that protects neurons against glaucoma in preclinical models. This discovery provides hope for devising a new strategy to protect vision in glaucoma patients and may have implications for other neurodegenerative diseases.
Scientists found microcolumns in layer V of the cortex, which are synchronized neural activity units. These units could represent an essential computational unit in the brain, similar to parallel computers.
SourceData provides a suite of tools to generate, validate and use figure data, making it efficient to find and reuse published results. The platform links figures to other related figures across papers and journals, creating a searchable knowledge graph.
Researchers discovered that our chromosomes age along with us, affecting how our immune system renews itself. In young people, thousands of gene sites are open, while in older adults, these sites become closed, leading to decreased activity in genes and pathways critical for defending against disease.
The NIH BRAIN Initiative has launched a major effort to discover and catalog the brain's diverse cell types. The BICCN will generate knowledge that is prerequisite to solving the mysteries of brain disorders such as schizophrenia, Alzheimer's disease, and autism spectrum disorder.
The pilot project identified significant bottlenecks in data sharing practices among IDRC-funded projects, including lack of resources, expertise, and tailored data management platforms. The study recommends empowering Program Officers with training and support to enhance policy implementation.
Researchers at the National University of Singapore have discovered a critical molecular target for sphingosine-1-phosphate production, paving the way for regulating its signalling in circulation. Low levels of S1P have been linked to various immune and vascular diseases, including multiple sclerosis and cardiovascular complications.
Researchers at Monash University have created the first high-resolution structure of the Type II secretion system in Pseudomonas aeruginosa, a critical component in the bacteria's ability to secrete toxins. This breakthrough could lead to the development of new drugs targeting this nanomachine to reduce virulence and combat infection.
The MyGene2 platform connects patients, clinicians, and researchers to share genetic data, phenotypes, and experiences. Over 1,000 profiles have been created, enabling matches among patients with the same disease and facilitating low-cost exome sequencing.
GA4GH has struck formal collaborations with 15 international genomic data initiatives, including Genomics England and the U.S. All of Us Research Program. The goal is to create framework and standards for responsible sharing of genomic data by 2022.
Researchers at Northwestern University discovered that surface polarization in mixed media increases the attraction among rare earth elements. This finding could make rare earth recovery faster, easier, and less expensive. The study's results have implications for separating rare earths as well as other elements and nuclear waste removal.
Springer Nature's new platform provides easy access to the largest collection of life sciences protocols and methods. Users can search and compare content using advanced knowledge models and AI-powered text mining technologies, with features like protocol landing pages that summarize key information.
A University of New South Wales researcher has uncovered documents that suggest Teddy Evans, Scott's second-in-command, may have been responsible for his leader's death and that of four others. Evans' actions, including stealing rations and failing to pass on orders, are believed to have contributed to the tragedy.
A Data Science Institute professor is leading a research team to develop an intelligent headphone system that detects sounds of approaching vehicles and sends audio alerts to pedestrians. The project aims to reduce pedestrian injuries and fatalities in crowded cities by providing a warning system for pedestrians wearing headphones.
Researchers discovered that yeast cells form protein aggregates in response to stress, which are then dissolved when the stress passes. The aggregates serve as a protective mechanism for essential enzymes, enabling the cell to quickly recover from stress.
The National Institute on Drug Abuse has awarded UCLA a $5 million grant to create a resource center for researchers studying the effects of substance abuse on HIV/AIDS. The Collaborating Consortium of Cohorts Producing NIDA Opportunities will connect researchers with access to millions of pieces of research data and lab samples.
The Magee Prize will be awarded to a collaborative team of researchers proposing innovative projects in women's health research. The winners will collaborate with MWRI researchers to improve women's health globally, focusing on topics like early human development, reproductive sciences, and gender-based biology.
UTHealth's Jim Zheng has been awarded a $5.8 million CPRIT grant to analyze cancer data and develop tools for analyzing cancer, with the goal of finding potential cures. The grant will fund the establishment of the Data Science and Informatics Core for Cancer Research at UTHealth.
The National Institutes of Health has awarded four grants to establish a coordinated scientific research effort on myalgic encephalomyelitis/chronic fatigue syndrome. Researchers will collaborate on projects, share data, and engage with the ME/CFS community to advance knowledge and potential treatments for this debilitating disease.
The Center for Solutions for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (CfS for ME/CFS) will pursue basic research and develop tools to monitor illness progression, while working closely with the ME/CFS community through partnerships and outreach.
Researchers found that metabolism directly impacts malaria development and severity. A study by Instituto de Medicina Molecular revealed that dietary shifts can lead to a 90% reduction in parasite load.
The National Institute of General Medical Sciences has awarded a $2.375 million grant to Van Andel Research Institute to study epigenetic control mechanisms that regulate the genetic code. The researchers aim to understand how these complex controls are orchestrated and leverage this knowledge to design more effective medications.
A study by Indiana University researchers found that US women have diverse preferences for genital touch, location, pressure, shape, and pattern, with 41% preferring a single style of touch. The study also revealed that nearly 75% of women require clitoral stimulation to achieve orgasm during intercourse.
Scientists in Bordeaux discovered a new mechanism for storing information in synapses and controlling the storage process. They found that halting receptor movement can block the acquisition of certain types of memories, confirming the role of synaptic plasticity.
Researchers discovered evidence of rapid climate changes on a millennial-to-centennial scale that occurred 780 to 760 thousand years ago. The findings suggest that this interglacial climate could be useful in predicting the Earth's future climate.