Scientists have discovered a common cause of all forms of ALS, a fatal neurodegenerative disease, by identifying a broken down protein recycling system in neurons. This finding provides a common target for drug therapy and suggests that all types of ALS are tributaries pouring into a common river of cellular incompetence.
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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.
TRIAD simplifies biomedical research by aggregating and analyzing rare data, reducing time spent on data translation. The platform is adopted by multiple institutions worldwide, including the National Cancer Institute, for groundbreaking projects like CLL Research Consortium.
The study found that boys are maturing physically earlier, while their social and economic roles are becoming more adult. This trend is linked to improved nutrition and disease environments.
The study replicated approximately 75% of the expected associations, demonstrating high-quality findings from self-reported data. 23andMe's web-based platform enables researchers to investigate hundreds of genetic factors in dozens of diseases efficiently and cost-effectively.
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Carbon nanotubes have been found to be reactive when a transition metal atom is present within the nanotube cavity, challenging previous scientific thinking. This discovery has significant implications for the development of new technologies, including gas storage devices and electronic components.
A team of researchers from the University of Valladolid analyzed 40 brands of beer and found that dark beer contains more free iron than pale and non-alcoholic beers. The average free iron content in dark beer was 121 ppb, while pale beer had an average of 92 ppb.
A University of New Hampshire researcher has discovered that Yale psychologist Arnold Gesell manipulated his photographic record to support his pro-eugenic thesis. Gesell's research falsely accused Alma, Wisconsin of being overrun with mentally and morally unfit people, a claim that has been debunked by the new discovery.
23andMe's Myeloproliferative Neoplasms (MPN) research initiative aims to recruit 1,000 individuals with these rare blood cancers to participate in genetic analysis and online discussions. The program will advance research and create a community for those affected by MPNs.
A new national collaboration of asthma genetics researchers has identified a novel gene association specific to populations of African descent, including the previously unreported PYHIN1 gene. The study also replicated four other gene associations with asthma risk, offering promising insights into the genetic roots of the disease.
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Scientists at MBL are investigating how jellies interact with their surroundings, the impact of the Gulf oil spill on animal development, and how fish process sound. Researchers are using a new underwater video camera system to study jelly behavior, while also exploring the potential health effects of the oil spill.
A team of researchers has identified a common mechanism between humans and zebrafish that regulates the circadian system. The discovery, published in PLoS Biology, could lead to new treatments for mental illness, metabolic diseases, and sleep disorders.
A recent study by Dr. Heather Piwowar found that cancer research is less likely to make its raw data available for reuse compared to other fields. Only 45% of gene expression studies were deposited in public databases, despite the importance of sharing these datasets for future research.
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The National Science Foundation awards four grants to create a national resource of digital data documenting existing biological collections. This will increase accessibility to valuable information and stimulate new research across multiple fields of science.
The SKA radio telescope has successfully linked its antennas over long distances using an optical fibre network, a key step towards observing distant galaxies in greater detail. The experiment saw six telescopes working together to observe a quasar 7.5 billion light-years away, revealing new insights into the universe.
A Czech University of Life Sciences team identified four new species of jewel beetles from local people in Southeast Asia. The discovery expands the genus Philanthaxia to 65 known species, emphasizing the need for biodiversity inventory and conservation efforts.
A team of researchers has discovered a naturally occurring disease in monkeys that shares similarities with multiple sclerosis, providing new insights into the cause of the disease. The discovery is associated with a herpes virus and could lead to significant advancements in MS research and treatment.
A new iPhone application, iTrem, has been developed to track hand and arm tremors in patients with Parkinson's disease. The app uses the iPhone's accelerometer to collect data, which can be used by physicians to remotely monitor patient disability and treatment response.
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A Japan-based research team studied the phase behavior of confined water in single-walled carbon nanotubes, discovering a wet-dry transition at low temperatures and tubule ice formation. The findings contribute to a deeper understanding of nanoconfined water and its potential applications in nanoscience.
The University of Missouri has secured a $5 million grant from the Coulter Foundation to support collaborative projects between biomedical engineers and clinicians. The funding will enable researchers to take their discoveries to clinical practice, with the goal of improving patient lives and suffering worldwide.
23andMe has built one of the world's largest databases with over 100,000 individuals' genetic data, facilitating rapid recruitment for genome-wide association studies. The company's novel research approach has led to new genetic associations for common traits and rare diseases.
Developing better modeling techniques for protein folding is vital to creating effective pharmaceutical treatments for diseases such as Alzheimer's and Parkinson's. The new algorithm can predict protein folding in 10 minutes on a laptop, improving upon classical methods that required hundreds of thousands of CPU hours.
Researchers have discovered that GPS stations can detect the impact of underground nuclear tests on the ionosphere, allowing for the confirmation of clandestine nuclear explosions. By analyzing changes in atmospheric electron density, scientists can pinpoint the location and timing of such events.
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Researchers have discovered that dolphins can generate two sound beam projections simultaneously, each with different frequencies and directions. This ability could help dolphins locate objects more accurately, according to Dr. Josefin Starkhammar, who led the study published in Biology Letters.
Researchers discovered Sox6 gene regulator that maintains fast muscle type and inhibits slow muscle development. Adult mice lacking Sox6 in fast muscles showed changes in muscle performance, including slower contraction speed and reduced fatigue.
A study by Marlene Behrmann and colleagues identifies a network of cortical areas working together to identify faces, changing the future of neural visual perception research. The discovery allows scientists to develop targeted remedies for disorders such as face blindness.
A study shows that web search queries can be used to detect and monitor outbreaks of dengue, a mosquito-borne virus, in near real-time. The research team developed an online tool that tracks epidemics using Google search results, which was found to be a viable source of information for early detection and monitoring.
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Researchers at the University of Calgary discovered that urban life is far from ideal for Prairie bats, contrary to expectations. Despite the presence of roosts and food sources in cities, bat populations exhibit poor body condition, reproductive rates, and juvenile survival.
A new study from George Mason University found that greater medical spending among Medicare participants leads to improved overall health and survival rates. The research team analyzed data from over 17,000 beneficiaries and discovered a positive correlation between increased medical care spending and better health outcomes.
A study by Brigham and Women's Hospital researchers found that copied lifestyle counseling documentation in EMRs is not associated with improved glucose control, similar to having received no counseling. The team suggests educating healthcare providers about the issue and exploring alternative solutions.
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Spanish researchers have discovered a previously unknown species of plant lice in Madrid, Spain using social network platforms. The discovery highlights the potential for online communities to aid in biodiversity research and monitoring.
Researchers have rediscovered four new species of purse-web spiders in South Africa, highlighting the urgent need for conservation efforts due to habitat loss and urbanization. The study provides valuable insights into the biology and evolution of these unique spiders.
A novel gene called MLIP has been identified as affecting heart development and the aging process. The discovery opens up new avenues for understanding cardiac development and loss of cardiac function.
Researchers discovered that ancient microbial mats could produce enough oxygen to support tiny, mobile life forms billions of years ago. The study challenges the long-held assumption that oxygen was necessary for animal evolution.
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The May issue of JAMIA features research on protecting provider identities during disease surveillance, rapid outbreak detection, and disparities in internet patient portal use in diabetes. The study highlights the importance of understanding people's information needs and social networks in improving healthcare services.
Researchers identified two mutations responsible for hereditary sensory and autonomic neuropathy type 1 (HSAN1), causing cognitive decline, hearing loss, and sensory impairments in young adults. The study provides insights into the disease's mechanisms and potential future research directions.
The study reveals that human proteins with Dermatan Sulfate affinity can become autoantigens, driving autoreactive B-1a cell responses and autoantibody production. Researchers identified over 200 autoantigens, including novel ones, which could lead to better diagnostics and personalized treatment for autoimmune diseases.
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Tel Aviv University's Dr. Sami Viskin has developed a new test to detect 'sudden death syndrome' in young athletes, which can be done at the patient's bedside using an electrocardiogram (ECG). The test detects a measurable difference in heart rate called the QT interval, which can help doctors identify patients at risk for sudden death.
Scientists from the University of Copenhagen have discovered three distinct clusters of intestinal bacteria, known as enterotypes, which affect digestion, energy metabolism, and drug absorption. These enterotypes are independent of nationality, gender, and age, providing a new biological fingerprint for personalized medicine.
The Rensselaer Polytechnic Institute has secured a five-year funding plan of $1.5 million from the U.S. Department of Energy Nuclear Criticality Safety Program to launch a new nuclear safety research program. The program aims to provide high-accuracy nuclear data for international nuclear community applications.
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A new study by Torsten Bornemann and Christian Homburg found that consumers who evaluate a product from a distance tend to interpret high prices as reflecting high quality. Consumers who face an immediate purchase focus on the role of price as an indicator of monetary sacrifice.
Scientists from Helmholtz-Zentrum Dresden-Rossendorf and TU Dresden created a unique material, Bi3Ni, with nanometer-scale size, which exhibits both ferromagnetism and superconductivity. This phenomenon is rare and not yet fully understood, with the possibility of featuring a special type of superconductivity.
Bicycle balance relies on a mixture of physical effects linked to mass distribution, not gyroscopic or caster effects. Researchers built a riderless bike that balanced itself without these effects.
Researchers found that male humpbacks sing the same mating tune, but with changing patterns over time, spreading across the ocean from west to east. The study revealed cultural transmission on a broad scale, similar to humans, as songs spread between populations in the Pacific Ocean.
MIT researchers develop new communications protocols using motion detection to improve handoffs, throughput and bit rate selection on wireless networks. Experiments show gains of up to 50% in network performance.
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A University of Guelph study found that male birds that stay behind gain better breeding sites and are more attractive to females, leading to increased mating success. In contrast, migrating birds are often in poorer condition and less likely to survive the heavy rains.
Researchers at Rensselaer Polytechnic Institute have developed a new method to boost enzymatic activity by confining enzymes in carefully engineered nanoscale holes. The study found that embedded enzymes exhibited significant increases in activity and retained their 3-D structure.
USDA scientists found bacterial strains producing the enzyme urease survive longer when fed to caterpillars, making them more effective at controlling pests. Researchers tested 50 strains and found that urease-producing phenotypes survived better when repeatedly fed to gypsy moths.
Navindra Seeram has discovered 54 beneficial compounds in pure maple syrup, with 20 previously identified compounds playing a key role in human health. The research also reveals anti-inflammatory properties and potential uses in fighting cancer, diabetes, and bacterial illnesses.
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A study of Joslin Medalists reveals that some individuals with diabetes for decades exhibit remarkably few complications, pointing to the presence of protective molecular mechanisms. The researchers identified a link between advanced glycation end products (AGEs) and both disease progression and protection.
Researchers have discovered a remarkable 525-million-year-old fossil of a 'feathered helmet from beyond the clouds,' offering insights into ancient biology and evolution. The find belongs to a group called pterobranch hemichordates, related to starfish and sea urchins.
Researchers found that asking participants to predict their future behavior breaks their habits, but this only works for behaviors with strong personal goals. For behaviors without personal norms, predicting the past behavior reinforces existing habits.
A recent study published in PubMed found that swiping contaminated plates three times significantly reduced bacterial counts. The mechanical removal of bacteria, not the disinfectant itself, was key to this effect. Saline wipes were found to be as effective as disinfectant wipes when swiped multiple times.
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Researchers have discovered the genetic fault behind a rare skin cancer that spontaneously heals after growing rapidly. The faulty TGFBR1 gene leads to unusual behavior in these self-healing squamous epithelioma tumors, which may help predict clinical effects of targeted therapies.
New study reveals humpback whale wintering grounds extend throughout Hawaiian Islands and into NWHI, contradicting previous assumptions. The discovery provides insights into the species' migration patterns and geographic expansion.
The Lupus Research Institute has awarded $3.6 million in grants to support cutting-edge research on the devastating disease. Investigators will explore how the immune system goes awry and develop novel approaches to correct manifestations that cause tissue and organ damage.
The Institute for Health Metrics and Evaluation (IHME) has launched the Global Health Data Exchange (GHDx), a user-friendly platform for searching and sharing global health data. The GHDx contains over 1,000 datasets, including surveys, censuses, administrative data, and hospital data, making high-quality metadata freely available.
Researchers at UCI have found a second form of phototransduction light sensing derived from vitamin B2, which challenges the long-held understanding of this process. This discovery may reveal new information about cellular processes controlled by light and has implications for optogenetics.
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Researchers at Northwestern University have discovered new shapes of microcompartment shells, including dodecahedra and octahedra, which can be used to create containers or microreactors with specific functions. These designed shells could efficiently deliver therapeutic materials to cells at targeted locations.
A study by the University of Salamanca found that Latin American immigrants in Spain earn around 20% less than Spanish workers with similar education and experience levels. The study, published in the Journal of Applied Economics, analyzed data from the 2006 Salary Structure Survey.
Researchers discovered a rare gene mutation strongly linked to schizophrenia, which could be a new target for effective treatment. The mutation affects the VIPR2 gene, leading to increased signaling in the Vasoactive Intestinal Peptide pathway.