'Neighbor maps' reveal the genome's 3-D shape
Researchers created a three-dimensional map of chromosomes, revealing their complex 3D structure. The 'neighbor maps' method uses proximity pairs to infer chromosome organization and geometry.
Experimental Data
Articles tagged with Experimental Data
Large volumes of data from ITER successfully transferred to Japan at unprecedented speeds
Scientists have successfully transferred massive amounts of data from ITER to Japan, paving the way for remote experiments and 'big data' analyses in fusion energy research. The achievement is made possible by a synergetic effect of collaboration between international partners.
UTA physicists to upgrade Titan supercomputer software for extreme scale applications
Physicists at UTA have been awarded a grant to upgrade the software running on the Titan supercomputer to support data-heavy scientific applications. The new system, Big PanDA, will improve operational efficiencies and enable efficient use of computing resources for a wider range of scientific applications.
Ten Reaxys® Ph.D. prize candidates selected to present at symposium in London
The Reaxys PhD Prize has shortlisted 10 candidates from 45 nominations, who will present their research in London and compete for the top three prizes. The jury's review criteria include originality, innovation, applicability, importance, and rigor of the reported research.
Study on a novel fault diagnosis method of rolling bearing in motor
A novel fault diagnosis method using resonance-based sparse signal decomposition and principal component analysis is proposed to diagnose early faults of rolling bearings. The experimental results show that the proposed method quickly discerns faulty elements, improving diagnostic accuracy.
Identification of an adrenaline receptor mutation in a family with atypical lipodystrophy
Researchers identified a genetic mutation in the ADRA2A gene that causes atypical lipodystrophy, characterized by excessive fat accumulation in the face and neck, but not in limbs. The mutation reduces adrenaline receptor function, leading to loss of lipid breakdown in adipocytes.
Targeting the PI3K/AKT/mTOR pathway in prostate cancer development and progression
The research article discusses experimental and clinical data on the pharmacological inhibition of the Akt/mTOR pathways, which play a vital role in prostate cancer. The blockade of this pathway may be necessary to increase standard therapies and improve treatment outcomes.
Scientists experimentally confirm electron model in complex molecules
Researchers have experimentally confirmed a mathematical model describing the distribution of delocalized electrons in molecules and crystals. The study uses X-ray diffraction data to demonstrate the approach's ability to detect electron delocalization, paving the way for new understanding of chemical bonding.
Improving cell transplantation after spinal cord injury: When, where and how?
Researchers found that transplanting olfactory ensheathing cells into damaged spinal cord areas significantly improves locomotor performance. The study analyzed 49 studies and identified key factors influencing the therapeutic effect, including timing of application and surgical micro-dissection.
Murine models of arrhythmogenic cardiomyopathy benefit from GSK3β inhibition
Researchers found that GSK3β inhibition improves cardiac function and reduces fibrosis and inflammation in murine models of arrhythmogenic cardiomyopathy. The study suggests GSK3β inhibition has potential as a therapeutic strategy for treating ACM.
Princeton graduate student creates program that helps stabilize fusion plasma
A Princeton graduate student has developed a program that helps stabilize fusion plasmas, reducing instabilities that decrease tokamak efficiency. The new method uses feedback from sensors for real-time control of plasma rotation and fuels fusion reactions.
How rivers of hot ash and gas move when a supervolcano erupts
A new study suggests that pyroclastic flows from a 18.8 million-year-old supervolcano eruption traveled in dense, slow-moving currents, covering over 100 miles. The research supports the idea that these flows are fluid-like, with pressurized gas between ash particles, and has implications for disaster preparedness efforts.
Most precise measurement of reactor antineutrino spectrum reveals intriguing surprise
The Daya Bay Collaboration has obtained the most precise measurement of reactor antineutrino energy spectrum ever recorded, showing a surprising excess of antineutrinos at an energy of around five million electron volts. This deviation of up to four standard deviations suggests that current calculations may need refinement.
A disposable, highly sensitive biosensing system
A highly sensitive and disposable Indium Tin Oxide (ITO) based biosensing tool was developed for the determination of Haptoglobin in human blood. The new biosensor features a low detection limit of 0.2 fg/mL and demonstrates high analytical performance.
The geometry of histamine understood by Russican scientists
Researchers from Lomonosov Moscow State University studied histamine molecules using gas electron diffraction and quantum-chemical calculations. They were able to determine the molecule's geometric structure and predict its mechanism of tautomerization, a spontaneous transition between structural states.
USC Viterbi School of Engineering Center funded under White House initiative
The USC Viterbi School of Engineering Center has been awarded an $8 million grant under the White House Materials Genome Initiative to develop new nanomaterials. The center will use open-source software, experimental data, and immersive visualizations to accelerate innovation in materials science.
Crunching numbers to combat cancer
The project aims to create an online cache of molecular data to validate current cancer models and make predictions about the disease. This will enable a collaborative approach to cancer treatment and potentially reduce animal testing in research.
Self-directed, iterative learning dramatically improves critical thinking in STEM classes
A self-directed, iterative learning framework dramatically improved first-year physics students' critical thinking skills, according to new University of British Columbia research. Students were four times more likely to identify and explain limitations in scientific models using their data.
Personalized banner ads are a double-edged sword
Researchers found that personalized ads showing only one item from a consumer's browsing history are more effective than those showing all items. Consumers reject ads due to privacy concerns and discomfort with intrusiveness if retailers lack trust with customers.
Scientists don't turn a blind eye to bias
A team of biologists reviewed nearly 900,000 experiments and found non-blind trials averaged a 27% stronger result than blind trials. The study suggests less than one in four experiments used blind data recording.
Scientists propose new model of mysterious barrier to fusion known as the 'density limit'
Researchers at PPPL have developed a detailed model of the source of the density limit, a puzzling limitation on fusion reactions. The findings suggest that a runaway growth of bubble-like islands can cause the plasma gas to cool and spiral apart, disrupting the reaction.
Ambiguous situations make it easier to justify ethical transgressions
Researchers found that situational ambiguity enables people to cheat and justify their actions more easily. In experiments, participants were more likely to report incorrect values when the correct answer was not clear, indicating a self-serving bias.
Fluctuation X-ray scattering
Fluctuation X-ray scattering measures molecules at short timescales to reveal structural insights into biological molecules and materials. The technique improves upon traditional small-angle X-ray scattering, providing greater detail from limited datasets.
3-D enzyme model provides new tool for anti-inflammatory drug development
Phospholipase A2 (PLA2) enzymes play a role in inflammatory diseases. Researchers created 3D models that show how PLA2 enzymes extract substrates from cell membranes, triggering inflammation. These models could help design and develop specific PLA2 inhibitor drugs.
Stock market models help NYU researchers predict animal behavior
Researchers at NYU Tandon School of Engineering have developed a mathematical model that can predict aspects of animal behavior using stock market models. This new model allows for more efficient experimentation and improved data analysis, enabling researchers to replace some experiments with computer modeling.
Global change: Trees continue to grow at a faster rate
A study by Technical University of Munich found that trees have accelerated their growth rate by up to 70% since the 1960s. The growth is attributed to rising temperatures, increased CO2, and nitrogen levels, which also led to a temporary slowing effect of acid rain on tree growth.
Researching fundamental rhythms of life
Casey Diekman is leading a research effort to understand the biological clock's role in regulating daily behavior patterns. Preliminary results suggest that circadian rhythms are deeply encoded in neuronal electrical programming, influencing hormone production and other physiological indicators.
Photon speedway puts big data in the fast lane
Scientists at Berkeley Lab and SLAC used a 'photon science speedway' to collect and analyze 114 terabytes of data on photosynthesis in just five days. The work led to new insights into how nature splits water molecules during photosynthesis, a key step towards developing artificial solar energy.
Risky situations increase women's anxiety, hurt their performance compared to men
A study by Susan R. Fisk found that women's anxiety in risky situations leads to worse task performance and lower grades than men, even when they have the same ability in non-risky settings.
New standards proposed for reporting spinal cord injury experiments
A new reporting standard has been proposed for spinal cord injury experiments to ensure uniformity in scientific reporting. The standard aims to facilitate the development of databases of experimental information, promoting the successful translation of treatments from laboratory to clinical settings.
Refocusing research into high-temperature superconductors
Scientists discover that collective movements of electron spins, not doping effects, are responsible for the formation of nematic phases. This finding opens up new avenues for understanding high-temperature superconductivity.
The breakthrough of hypervelocity launch performed on 3-stage light gas gun in CAEP
The Laboratory for Shock Wave and Detonation Physics Research at CAEP made significant progress in optimization of physical design, material processing, and experimental measurement technology. Experimental data on equation of state for materials under ultra-high pressure was obtained, leading to advancements in hypervelocity launch th...
On quantification of the growth of compressible mixing layer
The study of compressible mixing layers is crucial for propulsion design in high-speed vehicles. Researchers introduced a new framework called SED to analyze experimental data, providing evidence for nonlinear growth in CML. The findings suggest that lower growth rates are associated with large-scale vortices and inflow conditions.
Negative stereotypes can cancel each other out on resumes
Research by Princeton University graduate student David Pedulla found that negative stereotypes of gay men and black men can counteract each other for gay black men in employment, leading to higher starting salaries. This challenges the idea that membership in multiple marginalized groups leads to more discrimination.
Search tool for gene expression databases could uncover therapeutic targets, biological processes
A new computational tool called ExpressionBlast enables searches based on experimental values, revealing links between diseases and treatments. Researchers used the tool to uncover clues about SIRT6, a potentially important drug target involved in immune response, metabolism, and gender-specific gene regulation.
SU physicist develops model for studying tissue pattern formation during embryonic development
Physicist Lisa Manning and her team created a model to study tissue organization during embryonic development. They found that embryonic tissue behaves like a viscoelastic liquid, with cells packed tightly together like a cage of neighbors.
Beyond peer review: NIST and 5 journals find a way to manage errors in research data
A collaboration between NIST and 5 technical journals found that one-third of papers contained erroneous or incomplete chemical property data. A new online tool was developed to identify and eliminate errors in experimental data, using expert software system for data evaluation.
Go on, volunteer -- it could be good for you!
A new study published in BMC Public Health reveals that volunteering is associated with improvements in mental health and increased life satisfaction. Volunteers reported lower levels of depression and enhanced well-being, although the exact mechanisms underlying these benefits are unclear.
Study: Online tools accelerating earthquake-engineering progress
A new study has found that online tools, such as NEEShub and the project warehouse, are helping to accelerate progress in earthquake engineering and science. These platforms provide a centralized repository for experimental results, making them accessible to researchers, practitioners, and educational communities.
Scientists demonstrate pear shaped atomic nuclei
Researchers at the University of Liverpool have observed pear-shaped atomic nuclei, challenging current understanding and informing experimental searches for electric dipole moments. The discovery aids in refining nuclear theories and directs atomic EDM search programs.
A formula that can calculate a person's speed by just looking at their footprints
Spanish scientists have developed a formula that accurately calculates an individual's speed based on stride length, with a margin of error of 10-15%. The equation was tested using data from professional athletes and students, demonstrating its applicability in various environments.
BaBar data hint at cracks in the Standard Model
Recent BaBar experiment data suggest a potential flaw in the Standard Model, with a particular type of particle decay happening more often than predicted. The results are intriguing but require replication and further investigation to confirm or rule out an actual discovery.
Discarded data may hold the key to a sharper view of molecules
Scientists have developed a method to analyze noisy X-ray data, revealing details of molecular structure previously discarded due to low signal quality. This breakthrough could lead to more accurate models and improved understanding in biology, medical diagnostics, nanotechnology and other fields.
Decades of data show spring advancing faster than experiments suggest
Long-term historical observations reveal plants leafing and flowering sooner due to rising temperatures, contrary to results from controlled environmental warming experiments. This discrepancy suggests that estimated ecosystem changes may be far greater than current estimates based on experimental data.
Reproductive seasonality observed in male giant pandas
A study of eight male giant pandas found that reproductive fitness varies throughout the year, with waves of activity occurring 3-5 months before most females display estrus. This new understanding will help improve captive panda management and potentially aid in reintroducing pandas into the wild.
Major networking opportunity
The IMEx Consortium provides a single interface for querying experimental interaction data, making it easier to understand an organism's interactome. With over 100 million curated binary pairs, scientists can identify supported protein interactions and compare new results with publicly available data.
Finding your friends and following them to where you are
Computer scientists at the University of Rochester developed a model that can determine a person's location within a 100-meter radius using only their friends' locations on Twitter. The researchers achieved an accuracy rate of 85% in one experiment, tracking individuals to within one city block in over eight out of ten instances.
What does 'happiness' mean to consumers? Does age matter?
A new study in the Journal of Consumer Research found that people experience happiness through excitement and calmness, with younger individuals focusing on excitement and older individuals on calmness. Consumers' experiences of happiness drive their product choices, with marketers advised to consider individual differences.
New ONR technology will enable ship systems to share information seamlessly
The Office of Naval Research has demonstrated a new suite of information technology tools that could improve fleet operations by enabling seamless data sharing between ship systems. The technology, known as the universal gateway system, securely passes data between a ship's combat system network and its command-and-control network.
Video simulation puts a new twist on fusion plasma research
Researchers at the Princeton Plasma Physics Laboratory have created a video simulation showcasing the complex dynamics of a plasma pulse within an experimental fusion machine, offering new insights into particle confinement and magnetic field manipulation. The simulation provides a detailed 3D picture of the plasma, allowing researcher...
Study finds voters concerned with privacy in US elections
A Brigham Young University study found that voters who go against the neighborhood norm have less confidence in ballot privacy, with 30% less confidence. Election officials' shift to new voting technology has increased concerns among some voters about privacy.
Physicists report progress in understanding high-temperature superconductors
Researchers at the University of California, Santa Cruz, have made significant progress in explaining the unusual properties of high-temperature superconductors using a new theory. The theory, known as Extremely Correlated Fermi Liquids, shows remarkable agreement with experimental data from studies of high-temperature superconductors.
Search for dark matter narrowed by new data from XENON100
The XENON collaboration has announced results from a 100-day experiment, revealing no evidence of Weakly Interacting Massive Particles (WIMPs), leading candidates for dark matter. The high sensitivity achieved by the XENON100 detector may allow future detection in the near future.
Scientist develops new, innovative methods for characterizing proteins
A scientist at Florida State University has developed innovative techniques to characterize proteins, enabling faster and more accurate prediction of their structure and dynamics. This breakthrough could lead to the development of new drugs targeting specific proteins and designing new molecular machines.
Fruit flies use horizontal landmarks for altitude control, says Caltech research team
Caltech researchers found that flies regulate altitude by tracking horizontal edges, not the motion beneath them. This mechanism is similar to steering and was tested using an automated flight chamber with multiple cameras.
Breaking the logjam: Improving data download from outer space
Researchers used the International Space Station to test reconfigurable field-programmable gate arrays (FPGAs) and power converters, providing insights into high-energy radiation effects on computing electronics. The experiments aimed to mitigate potentially crippling effects in future processing-architecture designs.
Paper offers new insights into the genomics of speciation
A new study by University of Notre Dame biologist Jeffrey Feder challenges the prevailing assumption about genomic speciation. The research found that speciation in the classic apple maggot fly system involves genome-wide differentiation driven by natural selection.
Madly mapping the universe
Researchers have developed MADmap, a new software tool that improves the mapping of the cosmic microwave background by accounting for noise in the data. The software uses a special code to weight and account for colored noise, which is a known characteristic of bolometers used to measure radiation at certain wavelengths.
There's a speed limit to the pace of evolution, Penn biologists say
Researchers at Penn University developed a new theory that explains the pace of evolution and determines the speed at which an organism adapts. The study predicts that some organisms, including humans, may not evolve indefinitely and that populations can accrue mutations at a constant rate even under Darwinian selection.
New statistical technique improves precision of nanotechnology data
A new statistical analysis technique, sequential profile adjustment by regression (SPAR), has been developed to improve the precision of nanotechnology data. By identifying and removing systematic bias, noise, and equipment-based artifacts, SPAR can reduce experimental errors and increase confidence in measurements.