Research on the health and development of babies. Covers motor development, maternal-infant health, cochlear implants, and infant nutrition.
A recent study examined near-term and full-term newborns at Massachusetts General Hospital and found that the near-term group had significantly more diagnoses of clinical problems. The average hospital stay costs for near-term infants were also $2,600 higher than those of full-term infants.
Babies with complete DiGeorge syndrome, a fatal genetic disorder, are saved by a new combination of immune suppression and thymus transplantation. The technique reduces the risk of infection and allows infants to develop a functioning immune system.
Researchers discovered that inflammatory genes are activated and control bile duct obstruction in biliary atresia, a disease affecting up to 50% of children undergoing liver transplants. Blocking these inflammatory signals may prevent disease progression and increase long-term survival.
The meningococcal serogroup C conjugate (MCC) vaccine programme has successfully controlled the incidence of meningitis C, with high short-term effectiveness and substantial herd immunity. However, long-term efficacy remains unknown, with protection diminishing in children vaccinated in early infancy.
Researchers found that infants as young as five months detect subtle differences in object fit and space description between Korean and English languages. This suggests that humans have pre-existing concepts before acquiring language, which may influence the way we categorize objects and events.
A team of researchers has identified a gene linked to sudden infant death syndrome (SIDS), revealing a genetic basis for the syndrome. The gene, TSPYL, is expressed in both the brainstem and testes, and its alteration can cause sudden death in infants.
The teen birth rate has declined to a record low, and youth are less likely to be involved in violent crimes. However, the prevalence of overweight among children has increased, posing a risk for chronic conditions like diabetes and hypertension.
Research found that infants with higher maternal DHA levels at birth showed more mature attentional development and were less distractible during play. This suggests a potential link between DHA supplementation during pregnancy and improved infant cognitive functions.
A randomized trial found that two short drug regimens for infants at birth reduced mother-to-child transmission of HIV compared to a single regimen. The study suggests several options for prevention, including voluntary counseling and testing, standard NVP prophylaxis, and postexposure prophylaxis.
A US study of nearly 500 infants found that higher levels of endotoxin in the home were associated with a lower risk of developing eczema during their first year of life. Infants living in homes with dogs also had a reduced risk of eczema, but this relationship was weakened when adjusting for endotoxin exposure.
Research suggests moderate drinking may lower heart disease risk in older adults but increase breast cancer risk, particularly among women with family history or hormone replacement therapy. Moderate consumption also appears to reduce the risk of diabetes and metabolic syndrome.
The study shows that quality of childhood healthcare is good, but parents express a need for key child development issues. Parent satisfaction ratings are strongly related to the care received, increasing with more time, in-depth discussions, and family-centered care.
The Progresa program showed improvements in height increments and anemia rates among participants. Children who received the nutrition component experienced better growth and reduced risk of malnutrition.
A prospective study found that breastfed preterm infants had lower ratios of LDL to HDL cholesterol and CRP concentrations compared to formula-fed counterparts. Longer human milk intake was associated with additional benefits on cardiovascular health.
Common in 18- to 30-month-old children, scale errors occur when youngsters try to perform actions on miniature objects despite knowing they're too small. The study suggests a failure of inhibitory control and immaturity of the prefrontal cortex.
A new UNC study identifies specific eye features that can predict when premature infants are at risk of developing retinal detachment and total blindness. The study found that certain blood vessel growth patterns and vitreous cloudiness may indicate the need for surgical intervention to prevent progressive stage 4 ROP.
The NIAID-licensed rotavirus vaccine has been developed to combat severe diarrhea in infants and young children worldwide. The vaccine has shown promise in reducing the number of deaths caused by rotavirus infections, particularly in developing countries where access to effective treatments is limited.
Children with iron deficiency in infancy show persistent delays in both motor skills and cognitive abilities, even after treatment. These effects are most pronounced in children from low socioeconomic backgrounds, suggesting that addressing iron deficiency is crucial to mitigating long-term impacts on brain development.
Researchers found that MR-compatible incubators allow for high-quality imaging of critically ill newborns without radiation exposure. The incubators streamline the examination process and improve image resolution, enabling earlier and more accurate diagnoses.
Researchers found that an enzyme called superoxide dismutase helps prevent inflammation and promotes lung development in premature infants. This discovery could lead to improved treatments to alleviate chronic lung disease and preserve lung function.
A recent study published in Pediatrics found that breastfeeding for at least 28 days is associated with a 20% lower risk of dying between 28 days and one year of age. Longer breastfeeding duration also showed a similar benefit, indicating that even moderate breastfeeding can have a positive impact on infant mortality rates.
A study found that babies described as difficult eaters or overeaters are more likely to eat when their mother handles food and feed themselves after receiving a bite. This relationship was not seen in non-problem eater children, suggesting an innate link to social cues.
A recent study by Cincinnati Children's Hospital Medical Center suggests that human milk can significantly reduce the risk of severe infections in extremely low birth weight infants. The research analyzed data from 1270 infants and found that those who received human milk had a lower incidence of sepsis compared to those who did not.
A study found that furosemide inhalation alleviated severe breathlessness in patients with moderate to severe chronic obstructive pulmonary disease (COPD). Additionally, researchers developed a new model for neonatal bronchopulmonary dysplasia (BPD) using nasal continuous positive airway pressure (nCPAP) therapy.
The University of Pittsburgh is developing a heart assist device for infants with severe congenital heart defects, utilizing suspended magnetic levitation technology and miniaturization. The goal is to create a bridge-to-transplant device that allows infants to recover or survive until a donor heart becomes available.
Research found that women who received dental x-rays during pregnancy had a higher risk of having low birth weight infants, especially term low birth weight (TLBW) infants. The study suggested that eliminating all dental radiography during pregnancy could reduce the prevalence of TLBW infants by up to five percent.
A simple, inexpensive blood test performed at birth can screen for immune disorders like SCID and increase survival rates. The test, which costs $50, identifies infants with a profound deficiency of lymphocytes and has been shown to be effective in identifying children with other immune disorders.
Most families enrolled in early intervention programs report a satisfactory experience, but face challenges such as long wait times and limited access. The study highlights the need for improved systems to support families with children at risk of disabilities.
Research suggests that community-acquired pneumonia patients who are discharged from the hospital may face a higher risk of mortality in the subsequent 2-3 years if they have certain predictors, such as increasing age and cardiovascular disease. The study also found no excess mortality in younger patients without accompanying diseases.
A study found that infants fed protein hydrolysate formula for seven months developed a taste preference for the formula, while those fed standard milk-based formula rejected it. Early flavor exposure influences long-term food choices.
Researchers found no signs of impending brain injury from fetal heart rate monitoring, highlighting the need for alternative diagnostic methods. White matter brain injury is a common cause of cerebral palsy, but current monitoring systems may not be effective in detecting it.
Research reveals that prenatal alcohol exposure can cause slower processing speeds and arousal-regulation problems as early as infancy. Infants of mothers who consumed large amounts of alcohol during pregnancy showed higher levels of behavioral arousal but responded more slowly to stimuli.
Research found that how couples manage parenting responsibilities when their child is 6 months old affects the quality of their marriage when their child is 3 years old. Couples who had a good relationship with each other as infants but struggled with parenting conflicts were more likely to have poorer couple relationships later on.
A study published in The Lancet found that subdural hemorrhages in full-term babies are rare and typically resolve on their own. The research suggested that forceps-assisted deliveries and other trauma during birth may increase the risk of bleeding, but even then, it is usually not a cause for concern.
A recent UCSF study found that pediatricians' clinical judgment may be more effective than strict adherence to guidelines in managing febrile illnesses in infants. The study analyzed data from 3,066 infants and found that experienced clinicians using clinical judgment may reduce unnecessary hospitalizations and improve treatment outcomes.
Researchers found that 36% of infants were hospitalized, while 64% received treatment outside the hospital. Despite guideline non-adherence, infant mortality rates remained low.
A study in St. Louis, MO found that nearly half of poor African-American babies shared a bed with their mother, increasing SIDS risk. Providing safe cribs to these families reduced this risk by 78%.
Researchers found that mothers' brain activity increased when shown pictures of their own babies compared to others, indicating involvement of the orbitofrontal cortex in maternal attachment. The study's findings suggest a link between positive emotions and maternal bonding.
Infants begin to grasp intentional action in the first year, understanding actions as goal-directed and recognizing invisible connections between people and objects. This early knowledge lays the foundation for later developments in understanding intentions.
Researchers found that manual techniques can reduce permanent brachial plexus damage in babies by up to 50% compared to episiotomies. This approach also minimizes severe perineal injuries in mothers. The study suggests a safer and more effective alternative for managing severe shoulder dystocia during childbirth.
A four-year study published by Ohio State University researchers found that attempting a vaginal birth after C-section (VBAC) is associated with increased risk of maternal morbidity and serious obstetric complications. Despite this, many women continue to opt for VBAC due to the relatively low level of risk involved.
A new study published in the Canadian Medical Association Journal found that infants born over the weekend had a slightly elevated risk of stillbirth and neonatal death compared to those born on weekdays. The researchers suggested that selective timing of low-risk elective deliveries may explain this difference.
Recent studies suggest that pediatric influenza is a significant medical problem, causing excess hospitalizations and antibiotic prescriptions. Experts call for increased efforts to identify and vaccinate high-risk children, as well as educating parents and physicians about the importance of flu vaccination.
A European study has identified major risk factors for sudden infant death syndrome (SIDS), including prone sleeping positions and household smoking. These avoidable risk factors suggest a basis for further reductions in SIDS incidence rates through changes in infant sleep arrangements and environmental habits.
Research suggests that direct-quality indicators based on patient mortality are more effective in selecting high-performing hospitals for VLBW infants. The study found that hospitals with lower past mortality rates had significantly better outcomes, implying that volume-based standards may not accurately predict quality.
A new study by William Checkley and colleagues found that water and sanitation are key determinants of infant health in developing countries. The research, conducted on 230 Peruvian infants, revealed that inadequate water and sanitation can lead to higher rates of diarrheal episodes and stunted growth.
Environmental samples from food factories and households contained E. sakazakii, highlighting the need for preventive control measures. Health professionals should follow recommendations to handle reconstituted powdered infant formulas with care.
Researchers found that infants with reduced interferon gamma production at age 3 months and lower soluble CD14 levels at birth are 4.5 times more likely to develop recurrent wheezing. Chronic cough is also linked to abnormal release of inflammatory mediators within the airway, according to a separate study.
The use of rubella vaccine has increased globally, with 124 countries using it in their immunization programs by 2002. Surveillance for congenital rubella syndrome remains a concern, with incomplete reporting and estimated cases being only 0.1% of true total.
The incidence of pertussis among infants increased significantly between 1980 and 1999, with a 49% rise in reported cases. The majority of these cases occurred among infants under four months old, suggesting the need for improved vaccination strategies to control the spread of the disease.
Researchers found that early treatment of retinopathy of prematurity (ROP) in high-risk infants can prevent severe vision loss. The ETROP study demonstrated that premature infants who receive therapy in the early stage of the disease retain better vision than those who wait until their condition is more advanced.
The Duct Busters team repairs patent ductus arteriosus in premature newborns with high-quality surgical care, eliminating transport risks and allowing families to stay in familiar environments. The study found no significant differences in anesthesia-related complications or surgical outcomes between on-site and off-site procedures.
Researchers found that early treatment reduced the likelihood of poor vision from 19.5% to 14.5% and structural damage from 15.6% to 9.1% in high-risk premature infants. The study, published in the Archives of Ophthalmology, identified risk factors for ROP and showed that prompt treatment can prevent severe vision loss.
A five-year study in Germany found that early ultrasound screening reduced the number of subsequent hip operations from 147 to around 80-100. However, the effectiveness depends on timely screening before six weeks of age.
Research using fMRI scans found left-hemisphere activation in infant brains during speech stimulation, suggesting early language lateralization. The study challenges the long-held assumption that language dominance is progressive until puberty.
Researchers used fMRI to study infants with documented brain injury and found early evidence of left-hemisphere-dominant activation patterns during speech processing. This challenges the long-held assumption that language lateralization is progressive until puberty, instead suggesting a more complex process.
Research published in Journal of Multilingual Communication Disorders reveals that adopted Chinese children develop English language skills comparable to those of native-born peers. By age two, most children showed no evidence of delay and some had larger vocabularies.
A study found that nitric oxide can prevent lung disease and death in premature infants by reducing the risk of severe bleeding into the brain. The treatment, which involves adding small amounts of nitric oxide to oxygen, has been shown to improve survival rates and reduce the need for long-term ventilation.
A study of 327 infants found chorioamnionitis increases CP risk by 4 times, with maternal black ethnicity and older age also associated. Chorioamnionitis was present in 14% of cases and controls.
Researchers identified several factors that may enable or prevent HIV transmission through breastfeeding, including the hostile environment of saliva and immune activation in the gastrointestinal tract. Protective factors include natural killer cells, natural antibodies, and specific antibody responses.