Articles tagged with Morbidity
New research reveals a significant increase in stroke risk within 3 months of cancer diagnosis, with pancreatic and lung cancers showing the highest rates. The study, published in CANCER, found that younger patients and those with advanced cancer are particularly at risk.
A global study estimates the lifetime risk of developing and dying from colorectal cancer, revealing stark disparities by country, sex, and age. The study's findings highlight the need for tailored prevention and screening strategies, with a focus on high-HDI countries and low-resource settings.
A global study led by the Institute for Health Metrics and Evaluation found that road injuries in Singapore resulted in 9,680 years of healthy life lost in 2023. The study also highlights the need for safer roads, vehicles, and enforcement to prevent deaths and serious injuries.
A new study at Tampere University found that simple risk factors like body mass index, waist-to-hip ratio, and smoking habits are better predictors of chronic disease than epigenetic clocks. This challenges the marketing claims of biological age tests, which can cost hundreds of euros.
Researchers found that older adults with multiple chronic conditions are less alike, raising questions about one-size-fits-all clinical recommendations. The study suggests basing guidelines on each person's unique multimorbidity rather than chronological age alone.
A major study reveals the incidence of acute pancreatitis in South Australia has increased to above the global average, with growth rates highest among women and those living in wealthier areas. The condition is increasingly linked to gallstones and metabolic risk factors, shifting the profile of who is at risk.
A global study led by NUS Medicine found that Singaporeans have the highest life expectancy and healthy life expectancy, but a growing number of years are spent in poor health. The morbidity gap has widened globally, with people spending more years lived with illness or disability.
Researchers found that females with live offspring had lower late-life frailty, contradicting previous theories on a potential reproductive cost. The study used companion dogs to investigate the relationship between reproduction and aging, revealing a unique link between parity and robustness.
A new Global Burden of Disease study found that people are spending more years living with chronic disease and disability as global life expectancy increases. The analysis revealed that high-income countries face the widest morbidity gaps, while women consistently live longer but spend more years in poor health.
Global road injury rates declined by 38.3% for new cases and 32.3% for deaths between 1990 and 2023, but progress was uneven across income groups. Low- and middle-income countries bear the greatest burden, with nearly six times higher mortality rates than high-income countries.
A new nationwide Austrian study found that bone fractures are often part of a complex pattern of multiple conditions, underscoring the need for consistent osteoporosis screening at the time of a fracture. Osteoporosis is not systematically documented for many fracture types, highlighting a diagnostic gap, especially in men.
A new study reveals that ancient bacterial genomes from teeth of human remains found at four hunter-gatherer cemeteries in East Siberia reconstructed the earliest forms of plague. The findings suggest that these early strains were highly lethal and carried a unique superantigen, increasing the severity of infection.
The study found that antigenically drifted viruses caused substantial morbidity and mortality, but vaccines reduced risk of influenza among vaccinated individuals. Recommended antivirals remained effective in treating the virus.
Adults with prediabetes who undergo lifestyle intervention show a lower burden of multimorbidity compared to those not receiving the intervention. Lifestyle programs can persistently reduce the development of chronic conditions in this population.
Children and adolescents in Gaza who suffered penetrating traumatic brain injury during armed conflict experienced substantial morbidity and mortality. Survivors often endured neurological impairments and long-term psychosocial challenges.
Screening with a PSA blood test reduces prostate cancer deaths by approximately 2 for every 1,000 men screened. The review found that 500 men would need to be invited to screening to prevent one prostate cancer death.
A new study suggests that both very low and very high resting heart rates are associated with an increased risk of stroke. The research found a U-shaped pattern, with stroke risk lowest at heart rates of 60-69 bpm and highest at below 50 bpm or above 90 bpm.
The American Medical Association (AMA) has developed guidelines for treating anxiety disorders in adults in primary care settings. Behavioral therapy, including cognitive-behavioral therapy (CBT), and medication, such as selective serotonin reuptake inhibitors (SSRIs), are recommended treatments.
A new method called scSurvival uses single-cell genetic data to identify which cells inside a tumor are most strongly linked to patient survival. The approach pinpoints harmful and helpful cell populations that can drive disease progression, enabling better understanding of why patients with the same cancer have different outcomes.
Primary care-based discussions on reproductive goals, immunizations, and risk-reducing interventions optimize pregnancy outcomes. Prepregnancy counseling reduces maternal morbidity and mortality, while also promoting healthy fetal development.
A study extending pregnancy monitoring from conception to 6 weeks postpartum found nearly 10,000 cases of severe maternal complications in Canada each year. This reveals significant cases were previously missed, emphasizing the importance of postpartum care and timely interventions.
Researchers found that an increasing number of preexisting maternal chronic conditions increases the risk of severe neonatal morbidity and mortality. Women with multiple chronic conditions may benefit from preconception counseling, earlier identification of complications, and enhanced newborn supports to optimize outcomes.
A study found that TRAP laws increase maternal morbidity among fertility care patients, while states without such laws have better health outcomes. The study suggests a significant association between TRAP laws and adverse pregnancy outcomes.
A meta-analysis found nirsevimab to be associated with reduced hospitalizations and emergency department visits for lower respiratory tract infections in young children. This suggests the potential of nirsevimab to decrease respiratory-related morbidity in this population.
Experts warn that nicotine-containing products, including vapes, heated tobacco, and shisha, cause cardiovascular damage regardless of delivery system. The report highlights a rapid rise in youth addiction fueled by flavours and social media marketing.
Research shows that 77% of severely injured children are transported or transferred to pediatric trauma centers, highlighting the need for improved access and evidence-based strategies. Variability in access exists across Canadian provinces, with some areas having higher access than others.
A study published in JAMA Network Open found that older adults with chronic kidney disease or cerebrovascular disease are at double the risk for developing neuroinvasive West Nile virus infection, which can lead to paralysis and death. The study identified several risk factors, including male sex, immune suppressants, and multiple scle...
A cohort study of adults aged 45 or older with RSV infection found a significant excess risk of cardiovascular events over 1 year, comparable in magnitude to influenza infection. This highlights the importance of RSV as a potential risk factor for cardiovascular morbidity and underscores the need for vaccination to mitigate this burden.
A study by Brown University and Harvard University found that premature deaths are preventing many Americans from accessing Medicare benefits. The trend is particularly true for Black adults, who saw a 38% increase in premature deaths over the decade.
A study by the Gerald P. Murphy Cancer Foundation's Center for Exceptional Longevity Studies found that retaining gonad function can significantly impact frailty mortality risk. Male dogs with shortest testis exposure had high mortality risks, while those with longest gonad exposure showed no consequence of increasing frailty.
A new study in the Journal of Hepatology shows liver transplantation from MAiD donors yields similar survival rates as standard donation after circulatory death. This practice can significantly expand the donor pool, leading to more organs available for transplant and potentially saving thousands of lives.
The latest Global Burden of Disease study reveals declining global mortality rates, but rising youth deaths and widening health inequities. Non-communicable diseases account for nearly two-thirds of total death and disability, with ischemic heart disease, stroke, and diabetes leading the globe.
A UK Biobank study suggests that people with type 2 diabetes progress to additional chronic conditions at a faster rate than those without the condition. The study found that individuals with T2D experience a 60% higher risk of new disease diagnosis compared to those without T2D.
Rates of alcohol-induced deaths in the US nearly doubled between 1999 and 2024, reaching a record high in 2021. The largest increase was among females aged 25-34, with mortality rates rising by 255%.
A study of over 26,000 dogs reveals which diseases tend to co-occur and provide insights into canine healthcare. The network analysis suggests new connections between diseases, such as low iron and protein in the urine, and helps guide veterinary practice.
A case series of children with influenza-associated acute necrotizing encephalopathy highlights the condition's severe impact on young, previously healthy children. The study emphasizes the need for prevention, early recognition, intensive treatment, and standardized management protocols to address this critical public health concern.
A new study by NYU Langone Health researchers found that the shutdown of a significant fossil fuel pollution source near Pittsburgh, PA resulted in immediate improvements in respiratory health. Respiratory related emergency visits decreased by about 20% within weeks after the plant's closure.
A new study from Uppsala University found that most men with prostate cancer who receive recommended treatment have a good prognosis, with a lower risk of dying from prostate cancer than other causes. The study's findings highlight the importance of assessing a patient's life expectancy in choosing an appropriate treatment strategy.
Eastern equine encephalitis virus (EEEV) is a rare but deadly disease in the US, caused by a mosquito bite. People at risk include those living near swamps or marshes and outdoor workers, such as farmers and campers.
A cohort study suggests severe neonatal morbidity is a significant risk factor for childhood mortality, highlighting the importance of preventing and identifying early signs of severe conditions. Efforts to reduce mortality through infancy and late adolescence may benefit from targeted prevention strategies.
A cross-sectional study found elevated rates of severe maternal morbidity among marginalized racial and ethnic groups with planned cesarean births. The study emphasizes the need for interventions to improve quality of care and promote equity for this population.
A new study finds that Post-Intensive Care Syndrome (PICS) can lead to long-term deficits in cognitive function and ability to perform daily activities. The study identified key risk factors, including older age, frailty, and worse baseline cognition.
The University of Texas at Arlington has launched a new Mobile Simulation Lab to tackle workforce and training challenges in rural areas. The lab, equipped with advanced patient manikins and simulation bays, will provide specialized training for local healthcare providers to expand their expertise.
The UH Portage Medical Center's heart lab and prevention programs have shown a significant reduction in ischemic heart disease mortality, especially among older adults. The study found declines of 36% in the 65-74 age group and 28% in those over 85.
A new study from Karolinska Institutet found that patients with heart failure who stop taking medications like RASi, ARNi, or MRA have a higher risk of heart-related death or hospitalization. Despite improved symptoms and pump function, continued medication is crucial to prevent complications.
A Rutgers Health study found that closely monitoring blood pressure of post-partum mothers can lead to a 68% decrease in emergency department visits. The study also showed an improvement in blood pressures throughout the six weeks postpartum and trends towards decreasing hospital readmissions for hypertension.
Emissions from SUVs and light-duty trucks cause 90% of nitrogen dioxide-related deaths, with suburban driving linked to greatest health damages. The study's findings inform geographically targeted transportation policies and climate action plans for Boston and cities nationwide.
A study of Viking skulls using CT scans reveals a range of diseases including sinus and ear infections, osteoarthritis, and dental diseases. The results provide greater understanding of the health and wellbeing of the Viking population.
A large study on preterm birth found that a maternal biomarker test can reduce neonatal morbidities by 20% and NICU admissions by 20%. The test identified high-risk pregnant individuals, who received targeted treatment and showed significant improvements in neonatal outcomes.
A study found that pregnant patients with chronic hypertension and gestational hypertension are at a higher risk of severe maternal morbidity compared to those with normal blood pressure. The researchers suggest preventing preeclampsia in these patients may reduce this risk, making them comparable to normotensive patients.
A retrospective cohort study of 44,000 individuals found associations between baseline fasting glucose levels, age, sex, and body mass index with the development of diabetes. The study highlights individual variation in diabetes risk according to commonly measured clinical variables, suggesting potential for targeted interventions.
A recent study found that effective pediatric obesity treatment is associated with lower incidences of mortality in young adulthood. The treatment was also linked to reduced long-term morbidity, such as type 2 diabetes, dyslipidemia, and hypertension.
A Swedish study found a significant decrease in infant mortality and morbidity among babies born after 41 weeks of gestation. The study showed a 47% reduction in stillbirths or infant deaths within four weeks, with researchers attributing the improvement to routine induction practices.
A recent study found that pregnant individuals with opioid use disorder enrolled in Medicaid are at a disproportionately high risk of severe maternal morbidity. Targeted interventions, such as early Medicaid enrollment and coverage continuity, may be necessary to reduce adverse outcomes in this group.
Early detection of breast cancer can lead to less intensive treatments, saving the Canadian healthcare system $459.6M over women's lifetimes and 3,499 breast cancer deaths. Screening mammograms and diagnostics costs are easily offset by earlier stage treatment.
A new study published in JAMA found that women who experience severe maternal morbidity during their first pregnancy are less likely to have more children. The research, which studied over a million women in Sweden, revealed that such events can have a lasting impact on fertility.
Women who experience severe maternal morbidity in their first birth are less likely to have a subsequent birth. Enhancing antenatal care and reproductive counseling are crucial for women with this history.
A new study from Northwestern Medicine reveals a significant increase in severe maternal morbidity and birth complications in Illinois between 2016 and 2023. The findings highlight the impact of chronic health conditions such as obesity, hypertension, and mental health disorders on pregnancy outcomes.
New research highlights additional therapies being tested for hypoxic-ischemic encephalopathy (HIE) in newborns, including agents blocking glutamate receptor activation and antioxidant drugs. While therapeutic hypothermia is effective in high-income countries, its efficacy is uncertain in low- and middle-income nations.
A new study found that pregnant people in Massachusetts who made multiple unscheduled hospital visits during pregnancy were more likely to experience severe maternal morbidity. The study revealed that nearly half of these patients visited multiple hospitals, leading to inconsistent treatment and poor maternal outcomes.