Articles tagged with Morbidity
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The COVID-19 pandemic led to a significant decline in life expectancy globally, with countries in Eastern Europe and the US suffering worst losses. Vaccination efforts partially mitigated these impacts, particularly for older age groups.
A large randomized clinical trial demonstrated Octagam 10% as an efficacious and well-tolerated treatment option for adult dermatomyositis patients. The study showed improved outcomes in patients with this rare disease, providing a much-needed treatment alternative.
Researchers at the University of Alabama at Birmingham found that noninvasive ventilation in nano-preterm infants did not show an advantage in reducing bronchopulmonary dysplasia or death. In contrast, infants who received invasive respiratory support had lower rates of severe intraventricular hemorrhage and death.
Participation in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is associated with improved birth outcomes, including lower infant mortality. The review also found that WIC participants are more likely to receive child preventative services, such as vaccines.
The AABB has released clinical practice guidelines for the appropriate use of COVID-19 convalescent plasma, recommending its use for nonhospitalized patients at high risk for disease progression. The guidelines suggest that CCP is most effective when transfused with high neutralizing titers early after symptom onset.
The NIH announced five cash prize winners and four honorable mentions in its Maternal Health Diagnostics Challenge. The winning technologies aim to reduce maternal morbidity and mortality, with a focus on detecting and differentiating common pregnancy-related conditions.
The American College of Physicians (ACP) has issued a position paper on the ethical use of genetic testing and precision medicine in internal medicine. The guidelines address key issues such as incidental findings, education for physicians and patients, and counseling needs. ACP emphasizes the need for ongoing surveillance and anticoag...
A new study published in JAMA Surgery found that surgeons who oversee multiple surgeries simultaneously have a higher risk of complications and death. For surgeries involving one anesthesiologist directing CRNA or resident care, those managing three to four overlapping cases saw complication rates rise by 14%.
A Rutgers study found that women are more likely to die or require repeat surgery five years after abdominal aortic aneurysm repair. The researchers highlighted the need for increased inclusion of women in aortic device creation and trial enrollment, given differences in aortic anatomy between men and women.
Children born to mothers with polycystic ovary syndrome (PCOS) are at a higher risk of developing infections, allergies, and other childhood illnesses by age 13. The study found that children of mothers with PCOS were 32% more likely to be admitted to hospital for various health problems.
Research shows increased risk of severe maternal sickness/complications associated with higher maternal age, levels of obesity, and previous Caesarean section. The study suggests that UK maternity services are adapting to meet the needs of an increasingly complex pregnant population.
A longitudinal cohort study found significant reductions in liver disease and mortality among people with HCV infection who received treatment. The study's findings suggest that continued testing, treatment, and community-based interventions could lead to the elimination of HCV infection within the next decade.
A new study found that the fourth COVID-19 vaccine reduces the risk of death among elderly individuals in long-term care facilities by 72%. The study, which included approximately 40,000 residents, also showed a significant reduction in hospitalizations and infections.
A new study found that road fatalities and injuries kill more young people than communicable and non-communicable diseases or self-harm. The number of deaths attributed to road fatalities for adolescents has increased in some countries, particularly in low and low-middle income countries.
A new study published in iScience found that the co-development of the gut microbiome, immune system, and respiratory system is correlated with a baby's respiratory health. Disruption of any of these systems resulted in greater respiratory morbidity for infants, highlighting the importance of timing in intervening with therapies.
A new modeling study found that reducing excess prevalence of low birthweight, preterm birth, or small-for-gestational-age birth in low- and middle-income countries could lead to substantial long-term human capital gains. The study estimates potential gains of 20.3 million school years and $68.8 billion in lifetime income per birth coh...
Researchers linked dietary cholesterol to exacerbation of viral infections in mice, showing that high levels of cholesterol made mice sicker when infected with influenza. The study found that dietary cholesterol increased the number of cytokine-producing immune cells in the lungs, contributing to excessive inflammation.
A nationwide study analyzing rates of percutaneous coronary intervention (PCI) for ST-elevation myocardial infarction (STEMI) found a nearly 30% decline following the COVID-19 pandemic. STEMI cases have yet to recover to pre-pandemic levels, suggesting continued hesitation among patients to seek hospital care despite having a heart att...
A new study suggests that tailoring diabetes screening for Black, Hispanic, and Asian Americans based on lower BMI thresholds and younger ages can significantly reduce disparities in diabetes diagnosis rates. This approach may improve health equity by identifying cases earlier and reducing mortality rates associated with diabetes.
A systematic review and meta-analysis of 108 studies found that people with severe mental illness, including schizophrenia, have twice the cardiovascular-related mortality rate as the general population. The association has grown stronger over recent decades, with a possible link to changes in antipsychotic use and smoking prevalence.
A new study published in the Chinese Medical Journal assessed mortality risk in middle-aged and older Chinese individuals with multiple diseases. The study identified four multimorbidity patterns, with cardiometabolic being the most common, and found that individuals with these patterns had a significantly increased mortality risk.
Researchers at Karolinska Institutet studied long-term outcomes of bioprosthetic aortic valves implanted between 2003 and 2018. They found significant differences in performance depending on valve model, with Perimount having the lowest risk of replacement and mortality among patients
CLABSIs contribute significantly to infant morbidity and mortality in the NICU, leading to prolonged hospitalization and increased healthcare costs. The Society for Healthcare Epidemiology of America provides practical guidance on preventing CLABSI through implementation of specific strategies.
A study of vaginal births in New York State hospitals found that labor neuraxial analgesia – having an epidural or combined spinal and epidural – was associated with a decreased risk of severe maternal morbidity. The use of epidural anesthesia was linked to a 14% reduction in the risk of severe maternal morbidity, with racial and ethni...
A new study by Dr. Brian Stansfield and Dr. Jessica Gancar found a clear linear relationship between mortality and red blood cell transfusion volume in newborns on ECMO, with a 14% decrease in survival chances for every transfusion. The study suggests that reducing transfusion volumes may improve outcomes.
Adults with spinal cord injuries have a near-80% increased risk of developing psychological conditions compared to those without the injury. Chronic pain is equally negatively impacting mental health, associated with post-traumatic stress disorder and other mental health conditions in most cases.
A study of 236,000 individuals found patient- and prescription-related factors significantly linked to opioid-related fatal or nonfatal overdose. The research highlights the need for careful prescribing practices and post-discharge follow-up to prevent such overdoses.
A new study found high rates of trauma for mothers and babies from forceps and vacuum deliveries, with over 25% of forceps deliveries resulting in severe perineal tears. Researchers call for a reassessment of the safety of these birthing practices.
A new study by Carnegie Mellon University estimates that current regulatory analyses of air pollution significantly understate mortality costs among racial minorities. The study found that using race- and ethnicity-specific data increases premature mortality estimates related to PM2.5 from pollution exposure, with a $100 billion annual...
A new study reveals that poor women in rural India are more likely to die during childbirth due to lack of access to safe hospital births. The research found that only 26% of women in low-performing states deliver in hospitals, compared to 87% of those exposed to mass media.
Countries without face mask mandates experienced significantly higher COVID-19 deaths per million than those with mandates, according to a new study. Masks provided a supplementary layer of protection that could prevent unnecessary deaths.
Research suggests that severe maternal morbidity rates continue well into the late postpartum period, particularly among Black women, those with anxiety and depression. The study found alarming data showing increasing rates of maternal mortality later in the first year postpartum.
Researchers developed an AI program that accurately identified patients at risk of serious illness due to blood infections, with an accuracy rate of 82%. The technology has the potential to serve as an early warning system for doctors, enabling them to rank patients based on their risk level.
A new study reveals that childhood adversity is a major contributor to early and preventable causes of mortality and long-term physical and mental health issues. Childhood adversity was found to be associated with elevated risk for chronic diseases, including heart disease and cancer.
A new health program aims to improve pregnancy outcomes for Black patients by combining four evidence-based strategies, including racially concordant care providers and coordinated care. The five-year study will enroll 432 women and compare their experiences with usual maternity care versus a new model.
Researchers from UNC School of Medicine, MAHEC, and community partners will address racial disparities in maternal care by improving data accountability and providing community-based doula support. The study aims to decrease pregnancy complications for Black women and improve outcomes in maternal care.
The Patient-Centered Outcomes Research Institute (PCORI) has awarded $254 million to fund 28 new research studies aimed at reducing health disparities in maternal morbidity, preventing youth suicide, and improving behavioral health outcomes. Four studies will assess interventions to improve prenatal care for Black women and their child...
A study published in Obstetrics and Gynecology found that residents in majority-Black neighborhoods experience higher rates of severe pregnancy-related health problems. Neighborhood-level public health interventions may be necessary to lower these rates.
A study analyzing over 73 million hospitalizations found that site of delivery is a key factor contributing to racial disparities in maternal mortality. Black women are more likely to die from severe maternal morbidity at birth or immediately after childbirth compared to White and Hispanic women.
A study found that Medicaid expansion in 2014 NY increased maternal health, particularly for low-income and minority women. The policy intervention led to a statistically significant reduction in severe maternal morbidity.
A meta-analysis of three randomized studies found that induction at 41 weeks reduces perinatal death and morbidity compared to expectant management until 42 weeks. For first-time mothers, this approach results in a lower risk of severe illness or death in babies.
A recent supplement to Annals of Internal Medicine highlights the need to address maternal mortality and morbidity in the US. Research suggests that focusing on prenatal care, addressing inequities and disparities, and improving healthcare access are crucial steps forward.
Researchers found chronic inflammation in patrilineal communities was double that of men, while hypertension rates were reversed between matrilineal and patrilineal societies. Limiting women's autonomy and resources increased the risk of chronic diseases, according to the study.
Researchers are investigating factors contributing to preterm births among Black women, including social stressors and paternal roles. Chronic stress has been linked to increased risk of preterm birth, while perceived neighborhood environments may play a more significant role in stress levels than actual area conditions.
A Canadian study found that 68% of firearm-related deaths in Ontario were from self-harm, with most occurring among older men living in rural areas. The study highlights the need for targeted prevention efforts and suicide-prevention strategies in these regions.
A study by Columbia University's Mailman School of Public Health found that Medicaid expansion reduces the percentage of low-income women going uninsured or changing insurance plans during pregnancy and postpartum. The findings suggest that expanding Medicaid can improve access to care and reduce adverse events for pregnant women.
A new scoring system developed by NIH-funded researchers standardizes patient data to compare rates of severe maternal morbidity between different hospitals and groups of patients. The study aims to aid maternal health research and efforts to improve maternal health across the country.
Researchers discovered evidence of ear infections in 15,000-year-old human remains from the Levant, peaking around 6,000 years ago due to environmental factors. The study suggests that changes in living conditions, such as increased population density and poor hygiene, contributed to the prevalence of ear infections.
A new study has found that high blood glucose levels before pregnancy can increase the risk of severe maternal morbidity and death, even in women without diabetes. The study analyzed data from over 31,000 women and found that elevated hemoglobin A1c levels were associated with a higher risk of adverse outcomes
A study analyzing NYC birth data found stark differences in severe maternal morbidity risk across neighborhoods with extreme racial and economic polarization. Black and Latina women faced the largest magnitude of associations with severe maternal morbidity.
Researchers found that life expectancy in Switzerland has increased, but the country's population who only attended compulsory schooling are living longer in poor health. The gap between men and women is also widening, with women experiencing a smaller increase in healthy years due to their higher life expectancy
Research from NYU Rory Meyers College of Nursing finds that one in 270 births experience both premature birth and severe maternal complications. The study, which examined data from California births between 2007-2012, also reveals racial disparities in health outcomes, with Black women twice as likely to have a dual burden birth.
Over the past decade, US air pollution has led to a decline in mortality impacts from fine particle (PM2.5) pollution, but ground-level ozone (O3) pollution has remained relatively unchanged. This report estimates health impacts of air pollution for every US city and highlights the need for continued efforts to reduce these pollutants.
Research found that living alone is positively associated with common mental disorders across all ages and sexes. The prevalence of people living alone was linked to an increased risk of mental health issues, with loneliness explaining 84% of the association.
New research published in CMAJ found a higher risk of severe maternal complications after cesarean delivery, particularly among women aged 35 and older. Women under 35 had 1.5 times the odds of complications, while those over 35 had almost twice as high odds.
A recent NIH-funded analysis of California hospital records found a significant increase in severe maternal morbidity among US women from diverse racial and ethnic backgrounds. The study revealed substantial disparities in life-threatening birth complications, with non-Hispanic black women facing the highest rates.
A new study finds that 9m elderly men and 14m elderly women in India suffer from disabilities, with diabetes having the highest correlation to disability. The researchers suggest that acting in a timely way to address chronic morbidity can help minimize the burden of disability.
A new study analyzing nearly 40,000 hospital stays found that women of color and those with pre-existing health conditions had higher rates of severe maternal morbidity. The study highlights the importance of targeted prevention efforts to reduce racial and ethnic disparities in care for women around the time of delivery.
A recent USDA survey of 2,545 preweaned heifer calves across 104 dairy operations has provided valuable insights into calf health and management practices in the US. The study's findings will help improve the well-being of dairy heifer calves and inform more efficient calf-rearing practices.
The USPSTF recommends intensive behavioral interventions focusing on dietary changes and increased physical activity for adults with a BMI of 30 or higher. Obesity is associated with increased risks of coronary heart disease, type 2 diabetes, various types of cancer, disability, and death, particularly among adults younger than 65 years.