Articles tagged with Delirium
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A recent study published in Mayo Clinic Proceedings found that reducing the depth of sedation can decrease postoperative delirium prevalence by 50% in elderly patients undergoing hip fracture repair. Lighter sedation was associated with a reduction in delirium duration, averaging almost one day per patient.
Despite significant research efforts, no effective way to prevent or treat delirium has been identified. The study found that only 13 randomized controlled studies on promising drugs were conducted from 1966 to 2008, and none of them were effective in preventing or treating delirium.
A study published in Psychosomatics found that patients with severe hypoactive delirium have the worst six-month survival rate of any class of the disease. Delirium severity, rather than motoric subtype, is associated with higher risk of mortality at six months among patients without dementia.
Researchers found that oral treatment with melatonin before surgery can significantly reduce the occurrence of emergence delirium in children. Melatonin showed a direct dose-dependent effect on emergence delirium, with lower incidence rates at higher doses.
A leading gerontologist warns that new regulations may lead to a resurgence in physical restraints, which can cause medical complications and erode two decades of progress in reducing their use. Alternative strategies, such as the Hospital Elder Life Program (HELP), are more effective in preventing falls and maintaining patient safety.
Critically ill patients who received early physical and occupational therapy had better functional outcomes, shorter ICU delirium duration, and more ventilator-free days compared to standard care. This study highlights the benefits of whole-body rehabilitation in improving survival and recovery for critically ill patients.
Research published in Neurology shows that Alzheimer's patients who develop delirium experience rapid cognitive decline, with a rate three times faster than those without. The study suggests that preventing delirium may improve or delay memory problems.
Researchers at Beth Israel Deaconess Medical Center found that an episode of delirium rapidly accelerates cognitive decline and memory loss in Alzheimer's patients. The study, which analyzed data from 408 patients, revealed that the average decline on cognitive tests nearly doubled to 4.9 points per year following an episode of delirium.
A study published in JAMA found that dexmedetomidine reduced delirium prevalence and improved extubation times compared to midazolam, a commonly used sedative drug. The medication also showed a lower risk of bradycardia but higher tachycardia rates.
A retrospective cohort analysis involving over 280,000 patients found that statin use was associated with a 28% increased risk of postoperative delirium in elderly patients. The study also revealed that longer surgeries and age over 70 years increased the risk of delirium.
A basic educational programme boosts ICU nurses' ability to screen for delirium, surpassing expert performance in a standardised format. The programme's combination of lecture and practical exercises rapidly improves the capacity for nurses to perform delirium assessments accurately.
Dexmedetomidine was found to reduce the risk of delirium and coma in ICU patients on respirators, with 4 more days alive without these conditions. Dexmedetomidine also provided sustained sedation and higher accuracy at meeting sedation goals without added cost of care.
A special section of The Journal of Gerontology: Medical Sciences explores the relationship between delirium and dementia, finding potential biomarkers for delirium and a link between anesthesia and long-term delirium. Delirium is a common complication in older adults, affecting over 4 million individuals in the US each year.
Researchers explore relationship between delirium and dementia, finding potential biomarkers, neuroimaging techniques, and cognitive reserve factors. Delirium can be a major expense to healthcare systems, but interventions can decrease its incidence.
A study found that hospitalised older patients with delirium had a 13% shorter lifespan compared to those without delirium. The researchers estimate that this equates to approximately one year of life lost per patient.
A study of 260 non-ventilated patients found that delirium is a predictor of longer hospital stays and higher mortality rates. Patients experiencing delirium had a 29% greater risk of remaining in the ICU and a 41% greater risk of prolonged hospitalization.
A study of 90 patients reveals 50% experienced delirium, with distinct clusters of symptoms including psychotic problems, cognitive impairment, and mood disturbance. Early recognition is crucial to prevent poor outcomes, as delirium can lead to increased risk of falls, infections, and mortality.
A Yale University study found that children with increased preoperative anxiety are more likely to experience delirium and new maladaptive behavioral changes after surgery. Children who are younger, more emotional, and less social are at high risk of developing these issues.
A study published in Alcoholism: Clinical & Experimental Research suggests that variants of the BDNF gene may play a role in vulnerability to alcohol withdrawal-associated delirium tremens and violence while intoxicated. The study found a significant association between the G196A polymorphism and AA genotypes/A allele frequencies in al...
A study published in JAMA found a significant link between delirium in ICU patients and increased mortality rates. The researchers also highlighted the economic burden of treating delirium in ICUs, estimating costs ranging from $4 billion to over $20 billion nationwide.
A new treatment model at Saint Louis University Hospital eliminates traditional methods for caring for elderly patients with delirium. By placing patients in a Delirium Room with constant supervision, the hospital has significantly reduced fall rates and mortality rates.
A cross-sectional study found that only 35% of elderly patients with delirium were diagnosed in the emergency department, highlighting the need for improved detection methods. The study emphasizes the importance of developing better tools to identify delirium in ER settings.
A multidisciplinary team of specialists reduced episodes of delirium by 9.9% compared to standard hospital care, with benefits also seen in improved cognition, mobility, and hearing. The program targeted risk factors such as cognitive impairment, sleep deprivation, and immobility.